Bellingham Lab - Projects

Mechanisms of neurological disease:

• Pathogenesis and treatment of motor neuron disease in animal models
• Electrophysiology of neurotransmitter receptors and ion channels in motor neurons and other central neurons
• Developmental changes in and mechanisms of short and long term synaptic plasticity
• Neurobiology of addiction and relapse
• Neurobiology of autism

Synaptic transmission:

• Electrophysiology of neurotransmitter receptors and ion channels in motor neurons and other central neurons
• Developmental changes in and mechanisms of short and long term synaptic plasticity

Neurotransmitter receptors and ion currents in CNS neurones:

• Neurotransmitter receptor modulation of motor neurones - neuropharmacology and second messenger systems
• Effects of anaethetic agents on motor neuron excitability

Rhythmic control of movements:

• Role of glycine and GABA A receptors in programmed cell death of motor neurones and rhythmic movements
• Studies of ion currents controlling rhythm generation and computer models of single neurones and rhythmic networks