Role in lab

I am a biomedical research scientist in the Scott laboratory, with over ten years of laboratory experience in molecular genetics and neurobiology. I am currently leading a project on the autism spectrum.

Research Interests

My research interests are in the development and function of the cerebellum, in addition to the role that genetic factors play in causing phenotypical changes to cerebellar growth, foliation, molecular patterning, and function. Currently I am investigating the link between cerebellar dysfunction and autism spectrum disorder. This research is funded by consecutive grants from the Simons Foundation Autism Research Initiative.

Current project/s 

The impact of autism-risk genes on the behaviour and neurological function of zebrafish larvae

Published papers (updated through uq espace)

Constantin, Lena (2016) The role of microRNAs in cerebellar development and autism spectrum disorder during embryogenesis. Molecular Neurobiology, 1-16. doi:10.1007/s12035-016-0220-9

Constantin, Lena, Constantin, Myrna and Wainwright, Brandon J. (2016) MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell development. Genetics, 202 3: 1105-+. doi:10.1534/genetics.115.184176

Constantin, Lena and Wainwright, Brandon J. (2015) MicroRNAs promote granule cell expansion in the cerebellum through Gli2. Cerebellum, 14 6: 688-698. doi:10.1007/s12311-015-0672-x

Constantin, Lena (2011). The Role of Dicer in Cerebellar Development and Hedgehog-Mediated Medulloblastoma PhD Thesis, Institute for Molecular Bioscience, The University of Queensland [Thesis].

Researcher biography

I am a biomedical researcher at The University of Queensland, with over ten years of laboratory experience in molecular genetics and neurobiology. My research interests are in the development and function of the cerebellum, in addition to the role that genetic factors play in causing phenotypical changes to cerebellar growth, foliation, molecular patterning, and function. Currently I am investigating the link between cerebellar dysfunction and autism spectrum disorder. This research is funded by consecutive grants from the Simons Foundation Autism Research Initiative.