Journal Articles
Bettington, Mark, Liu, Cheng, Gill, Anthony, Walker, Neal, Leggett, Barbara, Whitehall, Vicki and Rosty, Christophe (2019) BRAF V600E immunohistochemistry demonstrates that some sessile serrated lesions with adenomatous dysplasia may represent collision lesions. Histopathology, 75 1: 81-87. doi:10.1111/his.13851
Liu, Cheng, Fennell, Lochlan J., Bettington, Mark L., Walker, Neal I., Dwine, Joel, Leggett, Barbara A. and Whitehall, Vicki L. J. (2019) DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas. Clinical Epigenetics, 11 1: 90. doi:10.1186/s13148-019-0691-4
Pai, Rish K., Bettington, Mark, Srivastava, Amitabh and Rosty, Christophe (2019) An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas. Modern Pathology, . doi:10.1038/s41379-019-0280-2
McCart Reed, Amy Ellen, Kalaw, Emarene, Nones, Katia, Bettington, Mark, Lim, Malcolm, Bennett, James, Johnstone, Kate, Kutasovic, Jamie Rose, Saunus, Jodi Marie, Kazakoff, Stephen, Xu, Qinying, Wood, Scott, Holmes, Oliver, Leonard, Conrad, Reid, Lynne Estelle, Black, Debra, Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Raghavendra, Ashwini, Harvey, Kate, Cooper, Caroline, Liu, Cheng, Kalinowski, Lauren, Reid, Andrew Scott, Davidson, Morgan, Pearson, John V, Pathmanathan, Nirmala, Tse, Gary, Papadimos, David, Pathmanathan, Rajadurai, Harris, Gavin, Yamaguchi, Rin, Tan, Puay Hoon, Fox, Stephen, O'Toole, Sandra A., Simpson, Peter Thomas, Waddell, Nicola and Lakhani, Sunil R. (2018) Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications. Journal of Pathology, . doi:10.1002/path.5184
Liu, Cheng, Bettington, Mark L., Walker, Neal I., Dwine, Joel, Hartel, Gunter F., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018) CpG island methylation in sessile serrated adenomas increases with age, indicating lower risk of malignancy in young patients. Gastroenterology, . doi:10.1053/j.gastro.2018.07.012
Bettington, Mark, Rosty, Christophe, Whitehall, Vicki, Leggett, Barbara, McKeone, Diane, Pearson, Sally-Ann and Walker, Neal (2018) A morphological and molecular study of proposed early forms of the traditional serrated adenoma. Histopathology, . doi:10.1111/his.13714
Bettington, Mark, Brown, Ian, Rosty, Christophe, Walker, Neal, Liu, Cheng, Croese, John, Rahman, Tony, Pearson, Sally-Ann, McKeone, Diane, Leggett, Barbara and Whitehall, Vicki (2018) Sessile serrated adenomas in young patients may have limited risk of malignant progression. Journal of Clinical Gastroenterology, 1. doi:10.1097/MCG.0000000000001014
Liu, Cheng, Walker, Neal I., Leggett, Barbara A., Whitehall, Vicki L. J., Bettington, Mark L. and Rosty, Christophe (2017) Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry. Modern Pathology, 30 12: 1728-1738. doi:10.1038/modpathol.2017.92
Brown, Ian S., Miller, Gregory, Bettington, Mark L. and Rosty, Christophe (2017) Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn’s disease-related ileitis. Virchows Archiv, 470 5: 597-597. doi:10.1007/s00428-017-2132-0
Liu, Cheng, Mckeone, Diane M., Walker, Neal I., Bettington, Mark L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2017) GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features. Histopathology, 70 7: 1079-1088. doi:10.1111/his.13180
Bettington, Mark, Walker, Neal, Rahman, Tony, Vandeleur, Ann, Whitehall, Vicki, Leggett, Barbara and Croese, John (2017) High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice. Internal Medicine Journal, 47 3: 318-323. doi:10.1111/imj.13329
Brown, Ian S. and Bettington, Mark (2017) Doxycycline induced oesophagitis: five cases highlighting a distinctive pattern of injury. Pathology, 49 1: 90-92. doi:10.1016/j.pathol.2016.09.066
Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, McKeone, Diane, Pearson, Sally-Ann, Leggett, Barbara and Whitehall, Vicki (2016) Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma. Gut, 66 1: 97-106. doi:10.1136/gutjnl-2015-310456
Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A. and Whitehall, Vicki L. J. (2016) RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget, 7 43: 70589-70600. doi:10.18632/oncotarget.12130
Brown, Ian S., Miller, Gregory C., Bettington, Mark L. and Rosty, Christophe (2016) Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn’s disease-related ileitis. Virchows Archiv, 469 5: 1-8. doi:10.1007/s00428-016-2009-7
Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex, Jeanjean, Marie, Chong, George, Fabre, Aurelie, Olschwang, Sylviane, Faulkner, Geoffrey J., Bellos, Evangelos, Coin, Lachlan, Rioux, Kevin, Bathe, Oliver F., Wen, Xiaogang, Martin, Hilary C., Neklason, Deborah W., Davis, Sean R., Walker, Robert L., Calzone, Kathleen A., Avital, Itzhak, Heller, Theo, Koh, Christopher, Pineda, Marbin, Rudloff, Udo, Quezado, Martha, Pichurin Pavel N., Hulick, Peter J., Weissman, Scott M., Newlin, Anna, Rubinstein, Wendy S., Sampson, Jone E., Hamman, Kelly, Goldgar, David, Poplawski, Nicola, Phillips, Kerry, Schofield, Lyn, Armstrong, Jacqueline, Kiraly-Borri, Cathy, Suthers, Graeme K., Huntsman, David G., Foulkes, William D., Carneiro, Fatima, Lindor, Noralane M., Edwards, Stacey L., French, Juliet D., Waddell, Nicola, Meltzer, Paul S., Worthley, Daniel L., Schrader, Kasmintan A. and Chenevix-Trench, Georgia (2016) Point mutations in Exon 1B of APC reveal gastric adenocarcinoma and proximal polyposis of the stomach as a familial adenomatous polyposis variant. American Journal of Human Genetics, 98 5: 830-842. doi:10.1016/j.ajhg.2016.03.001
Brown, Ian S., Bettington, Mark L., Bettington, Andrew, Miller, Gregory and Rosty, Christophe (2016) Adverse histological features in malignant colorectal polyps: a contemporary series of 239 cases. Journal of Clinical Pathology, 69 4: 292-299. doi:10.1136/jclinpath-2015-203203
Bettington, Mark, Brown, Ian S. and Rosty, Christophe (2016) Serrated lesions of the appendix in serrated polyposis patients. Pathology, 48 1: 30-34. doi:10.1016/j.pathol.2015.11.012
Brown, Ian S., Bettington, Andrew, Bettington, Mark and Rosty, Christophe (2015) Self-limited coeliac-like enteropathy: a series of 18 cases highlighting another coeliac disease mimic. Histopathology, 68 2: 254-261. doi:10.1111/his.12752
Bettington, Mark L and Chetty, Runjan (2015) Traditional serrated adenoma: An update. Human Pathology, 46 7: 933-938. doi:10.1016/j.humpath.2015.04.002
Bettington, Mark L., Walker, Neal I., Rosty, Christophe, Brown, Ian S., Clouston, Andrew D., McKeone, Diane M., Pearson, Sally Ann, Klein, Kerenaftali, Leggett, Barbara A. and Whitehall, Vicki L. (2015) A clinicopathological and molecular analysis of 200 traditional serrated adenomas. Modern Pathology, 28 3: 414-427. doi:10.1038/modpathol.2014.122
Rosty, Christophe, Campbell, Catherine, Clendenning, Mark, Bettington, Mark, Buchanan, Daniel D and Brown, Ian S (2015) Do serrated neoplasms of the small intestine represent a distinct entity? Pathological findings and molecular alterations in a series of 13 cases. Histopathology, 66 3: 333-342. doi:10.1111/his.12469
Bond, Catherine E., Bettington, Mark L., Pearson, Sally-Ann, McKeone, Diane M., Leggett, Barbara A. and Whitehall, Vicki (2015) Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups. BMC Cancer, 15 1: 20. doi:10.1186/s12885-015-1011-9
Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Mckeone, Diane, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara and Whitehall, Vicki (2015) Serrated tubulovillous adenoma of the large intestine. Histopathology, 68 4: 578-587. doi:10.1111/his.12788
Whitehall, V. L. J., Dumenil, T. D., McKeone, D. M., Bond, C. E., Bettington, M. L., Buttenshaw, R. L., Bowdler, L., Montgomery, G. W., Wockner, L. F. and Leggett, B. A. (2014) Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype. Epigenetics, 9 11: 1454-1460. doi:10.4161/15592294.2014.971624
Bettington, Mark, Lakhani, Sunil R. and Ung, Owen A. (2014) Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?. ANZ Journal of Surgery, 84 10: 725-729. doi:10.1111/ans.12497
Dumenil, Troy D., Wockner, Leesa F., Bettington, Mark, Mckeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014) Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue. Genes Chromosomes and Cancer, 53 7: 537-548. doi:10.1002/gcc.22164
Brown, Ian S., Bettington, Andrew, Bettington, Mark and Rosty, Christophe (2014) Tropical sprue: revisiting an underrecognized disease. American Journal of Surgical Pathology, 38 5: 666-672. doi:10.1097/PAS.0000000000000153
Bettington, Mark, Brown, Ian S., Kumarasinghe, M. Priyanthi, De Boer, Bastiaan, Bettington, Andrew and Rosty, Christophe (2014) The challenging diagnosis of cronkhite-canada syndrome in the upper gastrointestinal tract: A series of 7 cases with clinical follow-up. American Journal of Surgical Pathology, 38 2: 215-223. doi:10.1097/PAS.0000000000000098
Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Wockner, Leesa, Whitehall, Vicki and Leggett, Barbara (2014) Critical appraisal of the diagnosis of the sessile serrated adenoma. American Journal of Surgical Pathology, 38 2: 158-166. doi:10.1097/PAS.0000000000000103
Rosty, Christophe and Bettington, Mark (2014) Serrated colorectal polyps and polyposis. Diagnostic Histopathology, 20 1: 30-37. doi:10.1016/j.mpdhp.2013.12.005
Bettington, Mark and Brown, Ian (2014) Polyps and polypoid lesions of the anus. Diagnostic Histopathology, 20 1: 38-45. doi:10.1016/j.mpdhp.2013.12.001
Bettington, Mark, Walker, Neal, Clouston, Andrew, Brown, Ian, Leggett, Barbara and Whitehall, Vicki (2013) The serrated pathway to colorectal carcinoma: current concepts and challenges. Histopathology, 62 3: 367-386. doi:10.1111/his.12055
Conference Papers
Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Pearson, Sally-Ann, McKeone, Diane, Leggett, Barbara and Whitehall, Vicki (2015). A clinicopathological and molecular analysis of 107 sessile serrated adenomas with dysplasia. In: 104th Annual Meeting of the United States and Canadian Academy of Pathology, Boston, United States, (148A-148A). 21-27 March, 2015. doi:10.1038/labinvest.2015.11
Bettington, M., Walker, N., Brown, I., Rosty, C., Clouston, A., McKeone, D., Pearson, S-A, Leggett, B. and Whitehall, V. (2014). A clinicopathological and molecular appraisal of a large series of traditional serrated adenomas. In: 103rd Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), San Diego, United States, (165A-165A). Mar 01-07, 2014. doi:10.1038/labinvest.2014.22
Bettington, M., Walker, N., Brown, I., Rosty, C., Clouston, A., Pearson, S-A, Mckeone, D., Leggett, B. and Whitehall, V. (2014). Tubulovillous adenoma with prominent architectural serration - a clinicopathological and molecular appraisal of a new subtype of colorectal polyp. In: Australian Gastroenterology Week 2014, Broadbeach, Australia, (18-18). 22-24 October 2014. doi:10.1111/jgh.12736_2
Bettington, M., Bond, C., Brown, I., Walker, N., Rosty, C., Clouston, A., Pearson, S-A, Mckeone, D., Leggett, B. and Whitehall, V. (2014). Wnt signaling in an unselected series of colorectal carcinomas. In: Australian Gastroenterology Week 2014, Broadbeach, Australia, (19-19). 22-24 October 2014. doi:10.1111/jgh.12736_2
Bettington, M., Brown, I., Walker, N., Rosty, C., Clouston, A., Pearson, S-A, Mckeone, D., Leggett, B. and Whitehall, V. (2014). Changing incidence of BRAF and KRAS mutations in colorectal carcinoma. In: Australian Gastroenterology Week 2014, Broadbeach, Australia, (18-19). 22-24 October 2014. doi:10.1111/jgh.12736_2
Thesis
Bettington, Mark (2015). A clinicopathological and molecular categorisation of serrated colorectal polyps PhD Thesis, School of Medicine, The University of Queensland. doi:10.14264/uql.2015.871