Publications
Journal Articles
Wiegmans, Adrian P., Ward, Ambber, Ivanova, Ekaterina, Duijf, Pascal H. G., Adams, Mark N., Najib, Idris Mohd, Van Oosterhout, Romy, Sadowski, Martin C., Kelly, Greg, Morrical, Scott W., O’Byrne, Ken, Lee, Jason S. and Richard, Derek J. (2021). Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer. NAR Cancer, 3 (2), zcab022. doi: 10.1093/narcan/zcab022
Ham, Sunyoung, Lima, Luize G., Chai, Edna Pei Zhi, Muller, Alexandra, Lobb, Richard J., Krumeich, Sophie, Wen, Shu Wen, Wiegmans, Adrian P. and Moeller, Andreas (2018). Breast cancer-derived exosomes alter macrophage polarization via gp130/STAT3 signaling. Frontiers in Immunology, 9 (MAY) 871. doi: 10.3389/fimmu.2018.00871
Betts, Joshua A., Moradi Marjaneh, Mahdi, Al-Ejeh, Fares, Lim, Yi Chieh, Shi, Wei, Sivakumaran, Haran, Tropee, Romain, Patch, Ann.-Marie, Clark, Michael B., Bartonicek, Nenad, Wiegmans, Adrian P., Hillman, Kristine M., Kaufmann, Susanne, Bain, Amanda L., Gloss, Brian S., Crawford, Joanna, Kazakoff, Stephen, Wani, Shivangi, Wen Shu W., Day, Bryan, Moller, Andreas, Cloonan, Nicole, Pearson,John, Brown, Melissa A., Mercer, Timothy R., Waddell, Nicola, Khanna, Kum Kum, Dray, Eloise, Dinger, Marcel E. ... French, Juliet D. (2017). Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage. American Journal of Human Genetics, 101 (2), 255-266. doi: 10.1016/j.ajhg.2017.07.007
Lobb, Richard J., van Amerongen, Rosa, Wiegmans, Adrian, Ham, Sunyoung, Larsen, Jill E. and Moller, Andreas (2017). Exosomes derived from mesenchymal non-small cell lung cancer cells promote chemoresistance. International Journal of Cancer, 141 (3), 614-620. doi: 10.1002/ijc.30752
Peters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Wiegmans, A. P., Lim, H. F., Milevskiy, M. J. G., Azimi, I., Davis, F. M., Northwood, K. S., Pera, E., Marcial, D. L., Dray, E., Waterhouse, N. J., Cabot, P. J., Gonda, T. J., Kenny, P. A., Brown, M. A., Khanna, K. K., Roberts-Thomson, S. J. and Monteith, G. R. (2017). Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells. Oncogene, 36 (46), 6490-6500. doi: 10.1038/onc.2017.234
Wiegmans, Adrian P., Miranda, Mariska, Wen, Shu Wen, Al-Ejeh, Fares and Moller, Andreas (2016). RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy. Oncotarget, 7 (37), 60087-60100. doi: 10.18632/oncotarget.11065
Johnston, Rebecca L., Wockner, Leesa, McCart Reed, Amy E., Wiegmans, Adrian, Chenevix-Trench, Georgia, Khanna, Kum Kum, Lakhani, Sunil R. and Smart, Chanel E. (2016). High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations. Breast Cancer Research, 18 (18) 18, 1-18. doi: 10.1186/s13058-016-0681-9
Bessette, Darrell C., Tilch, Erik, Seidens, Tatjana, Quinn, Michael C. J., Wiegmans, Adrian P., Shi, Wei, Cocciardi, Sibylle, McCart-Reed, Amy, Saunus, Jodi M., Simpson, Peter T., Grimmond, Sean M., Lakhani, Sunil R., Khanna, Kum Kum, Waddell, Nic, Al-Ejeh, Fares and Chevenvix-Trench, Georgia (2015). Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib. PLoS One, 10 (5) e0125232, e0125232-e0125232. doi: 10.1371/journal.pone.0125232
Al-Ejeh, Fares, Shi, Wei, Miranda, Mariska, Simpson, Peter T., Vargas, Ana Cristina, Song, Sarah, Wiegmans, Adrian P., Swarbrick, Alex, Welm, Alana L., Brown, Michael P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2013). Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor. Journal of Nuclear Medicine, 54 (6), 913-921. doi: 10.2967/jnumed.112.111534