Professor David Craik

Schirra, Horst Joachim and Craik, David J. (2019). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance. (pp. 1195-1202) Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/1-4020-3910-7_128

Agwa, Akello J., Craik, David J. and Schroeder, Christina I. (2019). Cyclizing disulfide-rich peptides using sortase A. Methods in Molecular Biology. (pp. 29-41) edited by Timo Nuijens and Marcel Schmidt. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-9546-2_3

Craik, David J. and Peacock, Hayden (2018). Overview of NMR in drug design. Modern Magnetic Resonance. (pp. 1971-1981) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28388-3_112

Kan, Meng-Wei and Craik, David J. (2018). Trends in cyclotide research. Cyclic peptides: from bioorganic synthesis to applications. (pp. 302-339) edited by Jesko Koehnke, James Naismith and Wilfred A. van der Donk. Cambridge: Royal Society of Chemistry. doi: 10.1039/9781788010153-00302

Oguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2017). Cyclotides: plant defense toxins. Plant toxins. (pp. 221-243) edited by P Gopalakrishnakone, Célia R Carlini and Rodrigo Ligabue-Braun. Dordrecht, The Netherlands: Springer, Dordrecht. doi: 10.1007/978-94-007-6464-4

Craik, David J. and Peacock, Hayden (2017). Overview of NMR in drug design. Modern magnetic resonance. (pp. 1-11) edited by Graham A. Webb. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28275-6_112-1

Oguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2017). Cyclotides: plant defense toxins. Plant toxins. (pp. 221-242) edited by P. Gopalakrishnakone, Célia Regina Carlini and Rodrigo Ligabue-Braun. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-6464-4_7

de Veer, Simon J. and Craik, David J. (2017). Naturally occurring disulfide-rich cyclic peptides from plants and animals: Synthesis and biosynthesis. Chemical biology of natural products. (pp. 491-529) edited by David J. Newman, Gordon M. Cragg and Paul Grothaus. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315117089-14

Craik, David J., Kaas, Quentin and Wang, Conan K. (2017). A practical guide to structural aspects of macrocycles (NMR, x-ray, and modeling). Practical medicinal chemistry with macrocycles: Design, synthesis, and case studies. (pp. 25-57) edited by Eric Marsault and Mark L Peterson. Hoboken, New Jersey, United States: John Wiley & Sons. doi: 10.1002/9781119092599.ch2

Craik, David J. (2015). Overview on the discovery and applications of cyclotides. Advances in Botanical Research. (pp. 1-13) edited by Craik, DJ. Maryland Heights, United States: Academic Press. doi: 10.1016/bs.abr.2015.09.008

Henriques, Sonia Troeira and Craik, David J. (2015). Discovery of peptide drugs from natural sources. Peptide chemistry and drug design. (pp. 203-245) edited by Ben M. Dunn. Hoboken NJ, United States: John Wiley & Sons. doi: 10.1002/9781118995303.ch6

Oguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2015). Natural functions and structure-activity relationships of cyclotides. Advances in Botanical Research. (pp. 187-226) edited by Craik, DJ. Maryland Heights, United States: Academic Press. doi: 10.1016/bs.abr.2015.10.001

Akcan, Muharrem and Craik, David J. (2015). Engineering venom peptides to improve their stability and bioavailability. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. (pp. 275-289) edited by Glenn F. King. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00275

Kaas, Quentin and Craik, David J. (2014). Conotoxins and other conopeptides. Outstanding Marine Molecules: Chemistry, Biology, Analysis. (pp. 319-332) edited by Stéphane La Barre and Jean-Michel Kornprobst. Weinheim, Germany: Wiley-VCH Verlag. doi: 10.1002/9783527681501.ch14

Northfield, Susan E., Poth, Aaron, D'Souza, Charlotte and Craik, David J. (2014). Cyclotide analysis. Encyclopedia of Analytical Chemistry. (pp. 1-18) edited by Robert A. Meyers. Hoboken, NJ, USA: John Wiley & Sons. doi: 10.1002/9780470027318.a9933

Akcan, Muharrem and Craik, David J. (2013). Synthesis of cyclic disulfide-rich peptides. In Knud J. Jensen, Pernille Tofteng Shelton and Soren L. Pedersen (Ed.), Peptide synthesis and applications 2nd ed. (pp. 89-101) New York, NY, United States: Springer. doi:10.1007/978-1-62703-544-6_6

Craik, David J., Henriques, Sonia Troeira, Mylne, Joshua S. and Wang, Conan K. (2012). Cyclotide isolation and characterization. Natural product biosynthesis by microorganisms and plants, part B. (pp. 37-62) edited by David A. Hopwood. Burlington, USA: Elsevier. doi: 10.1016/B978-0-12-394291-3.00024-1

Daly, Norelle L., Gruber, Christian W., Goransson, Ulf and Craik, David J. (2011). Cystine knot folding in cyclotides. Folding of disulfide proteins. (pp. 43-61) edited by Chang, RJY and Ventura, S. New York , NY, U.S.A.: Springer. doi: 10.1007/978-1-4419-7273-6

Akcan, Muharrem and Craik, David J. (2011). Conotoxin-based leads in drug design. Peptide drug discovery and development: Translational research in academia and industry. (pp. 119-137) edited by Miguel Castanho and Nuno C. Santos. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527636730.ch5

Kaas, Quentin, Westermann, Jan-Christoph, Troeira Henriques, Sonia and Craik, David J. (2010). Antimicrobial Peptides in Plants. Antimicrobial Peptides: Discovery, Design, and Novel Therapeutic Strategies. (pp. 40-71) edited by Guangshun Wang. Wallingford, Oxfordshire, UK: CAB International. doi: 10.1079/9781845936570.0040

Craik, David J., Smith, Philippa A. and Clark, Richard James (2010). NMR-based screening and drug discovery. Burger's medicinal chemistry, drug discovery, and development. (pp. 359-437) edited by Donald J. Abraham, David P. Rotella and Alfred Burger. Hoboken, N.J.: Wiley. doi: 10.1002/0471266949

Dornenburg, Heike and Craik, David J. (2010). Cyclotides. Encyclopedia of industrial biotechnology: Bioprocess, bioseparation, and cell technology. (pp. 1849-1866) edited by Michael C. Flickinger. Hoboken, NJ United States: Wiley. doi: 10.1002/9780470054581.eib250

Wang, Conan K., Huang, Yen-Hua, Greenwood, Kathryn and Craik, David J. (2010). Membrane binding of cyclotides. Membrane-active peptides: Methods and results on structure and function. (pp. 597-672) edited by Miguel A.R.B. Castanho. La Jolla, CA, U.S.A.: International University Line.

Jan Westermann and Craik, David J. (2010). Plant peptide toxins from nonmarine environments. Comprehensive natural products II: Chemistry and biology. (pp. 257-285) edited by Mander, Lewis and Liu, Hung-Wen. Oxford,U.K.: Elsevier Science. doi: 10.1016/B978-008045382-8.00115-5

Rosengren, K. Johan, Daly, N. L. and Craik, D. J. (2009). NMR of peptide toxins. Annual reports on NMR Spectroscopy. (pp. 89-147) edited by Graham A. Webb. Oxford England U.K.: Academic Press Elsevier. doi: 10.1016/S0066-4103(09)06802-1

Daly, N. L. and Craik, D. J. (2009). Folding motifs of cystine-rich peptides. Oxidative folding of peptides and proteins. (pp. 318-344) edited by Johannes Buchner and Luis Moroder. Cambridge, UK: Royal Society of Chemistry.

Jan Westermann and Craik, David J. (2008). NMR in peptide drug development. Peptide-Based Drug Design (Methods in Molecular Biology). (pp. 87-113) edited by Laszlo Otvos. New York: Humana Press. doi: 10.1007/978-1-59745-419-3

Craik, D. J. and Clark, R. J. (2008). Structure-based Drug Design and NMR-based screening. Pharmacology from drug development to gene therapy. (pp. 225-313) edited by R. A. Meyers. Weinheim: Wiley-VCH Verlag GMBH & Co.

Schirra, H. J. and Craik, D. J. (2006). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance Part 2: Applications in Medical and Pharmaceutical Sciences. (pp. 1177-1184) edited by Graham A. Webb. Netherlands: Springer.

Cemazar, M. and Craik, D. J. (2006). NMR and Structural Genomics in the Pharmaceutical Sciences. Modern Magnetic Resonance Part 2: Applications in Medical and Pharmaceutical Sciences. (pp. 1411-1419) edited by Graham A. Webb. Netherlands: Springer.

Craik, D. J. and Clark, R. J. (2005). Structure-based drug design and NMR-based screening. Encyclopdeia of Molecular Cell Biology and Molecular Medicine. (pp. 517-605) edited by Robert A Meyers. Germany: Wiley-VCH.

Craik, D. J. and Clark, R. J. (2003). NMR and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery, Vol 1, Drug Discovery. (pp. 507-582) edited by Donald J Abraham. USA: John Wiley & Sons.

Craik, D. J. and Scanlon, M. J. (2000). Pharmaceutical Applications of NMR. Annual Reports on NMR Spectroscopy. (pp. 115-174) edited by Webb and GA. USA: Academic Press.

Craik, D. J. and Scanlon, M. J. (2000). Marine toxins as a starting point for drugs. Seafood and Freshwater Toxins Pharmacology, Physiology and Dection. (pp. 715-740) edited by Luis M Botana. New York: Marcel Dekker Inc.

Pinto, Meri Emili F., Chan, Lai Yue, Koehbach, Johannes, Devi, Seema, Gründemann, Carsten, Gruber, Christian W., Gomes, Mario, Bolzani, Vanderlan S., Cilli, Eduardo Maffud and Craik, David J. (2021). Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytes. Journal of Natural Products acs.jnatprod.0c01069. doi: 10.1021/acs.jnatprod.0c01069

Benfield, Aurélie H., Defaus, Sira, Lawrence, Nicole, Chaousis, Stephanie, Condon, Nicholas, Cheneval, Olivier, Huang, Yen-Hua, Chan, Lai Yue, Andreu, David, Craik, David J. and Henriques, Sónia Troeira (2021). Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells. Biochimica et Biophysica Acta - Biomembranes, 1863 (1) 183480, 183480. doi: 10.1016/j.bbamem.2020.183480

Peigneur, Steve, da Costa Oliveira, Cristina, de Sousa Fonseca, Flávia Cristina, McMahon, Kirsten L., Mueller, Alexander, Cheneval, Olivier, Cristina Nogueira Freitas, Ana, Starobova, Hana, Dimitri Gama Duarte, Igor, Craik, David J., Vetter, Irina, de Lima, Maria Elena, Schroeder, Christina I. and Tytgat, Jan (2021). Small cyclic sodium channel inhibitors. Biochemical Pharmacology, 183 114291, 114291. doi: 10.1016/j.bcp.2020.114291

Rehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, Durek, Thomas and Craik, David J. (2020). Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching. Angewandte Chemie ange.202013584. doi: 10.1002/ange.202013584

Tombling, Benjamin J., Lammi, Carmen, Lawrence, Nicole, Gilding, Edward K., Grazioso, Giovanni, Craik, David J. and Wang, Conan K. (2020). Bioactive cyclization optimizes the affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) peptide inhibitor. Journal of Medicinal Chemistry acs.jmedchem.0c01766. doi: 10.1021/acs.jmedchem.0c01766

Handley, Thomas N. G., Harvey, Peta J., Wang, Conan K., Lawrence, Nicole and Craik, David (2020). Cyclotide structures revealed by NMR, with a little help from X-ray crystallography. Chembiochem, 21 (24) cbic.202000315, 3463-3475. doi: 10.1002/cbic.202000315

Du, Qingdan, Huang, Yen-Hua, Bajpai, Abhishek, Frosig- Jorgensen, Majbrit, Zhao, Guangzu and Craik, David J. (2020). Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus. Journal of Natural Products, 83 (12), 3736-3743. doi: 10.1021/acs.jnatprod.0c01045

Jackson, Mark A., Nguyen, Linh T. T., Gilding, Edward K., Durek, Thomas and Craik, David J. (2020). Make it or break it: plant AEPs on stage in biotechnology. Biotechnology Advances, 45 107651, 107651. doi: 10.1016/j.biotechadv.2020.107651

Muller, Jessica A. I., Lawrence, Nicole, Chan, Lai Yue, Harvey, Peta J., Elliott, Alysha G., Blaskovich, Mark A. T., Gonçalves, Jacqueline C., Galante, Priscilla, Mortari, Marcia R., Toffoli-Kadri, Mônica C., Koehbach, Johannes and Craik, David (2020). Antimicrobial and anticancer properties of synthetic peptides derived from the wasp Parachartergus fraternus. Chembiochem : a European journal of chemical biology cbic.202000716. doi: 10.1002/cbic.202000716

Qu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6). doi: 10.1007/s00425-020-03505-z

Amiss, Anna S., Webb, Jessica R., Mayo, Mark, Currie, Bart J., Craik, David J., Henriques, Sónia Troeira and Lawrence, Nicole (2020). Safer in vitro drug screening models for melioidosis therapy development. The American journal of tropical medicine and hygiene, 103 (5), 1846-1851. doi: 10.4269/ajtmh.20-0248

Huynh, Peter N., Harvey, Peta J., Gajewiak, Joanna, Craik, David J. and Michael McIntosh, J. (2020). Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors. Biochemical Pharmacology, 181 114124, 114124. doi: 10.1016/j.bcp.2020.114124

Turner, Ashlin, Kaas, Quentin and Craik, David J. (2020). Hormone-like conopeptides – new tools for pharmaceutical design. RSC Medicinal Chemistry, 11 (11), 1235-1251. doi: 10.1039/d0md00173b

Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2020). Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science e24209. doi: 10.1002/pep2.24209

Peacock, Hayden, Henriques, Sónia Troeira, Benfield, Aurélie H., Elliott, Alysha G., Luo, Jinghui, Luccarelli, James, Nagano, Masanobu, Craik, David J. and Hamilton, Andrew D. (2020). Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activity. ChemMedChem, 15 (20) cmdc.202000474, 1932-1939. doi: 10.1002/cmdc.202000474

Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Israel, Mathilde R., Harvey, Peta J., Poth, Aaron G., Rehm, Fabian B. H., Stow, Jennifer L., Robinson, Samuel D., Yap, Kuok, Brown, Darren L., Hamilton, Brett R., Andersson, David, Craik, David J., Vetter, Irina and Durek, Thomas (2020). Neurotoxic peptides from the venom of the giant Australian stinging tree. Science Advances, 6 (38) eabb8828, 1-10. doi: 10.1126/sciadv.abb8828

Bleackley, Mark R., Vasa, Shaily, Harvey, Peta J., Shafee, Thomas M. A., Kerenga, Bomai K., Soares da Costa, Tatiana P., Craik, David J., Lowe, Rohan G. T. and Anderson, Marilyn A. (2020). Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteins. Journal of Fungi, 6 (3) 145, 145-14. doi: 10.3390/jof6030145

Wang, Conan K., Amiss, Anna S., Weidmann, Joachim and Craik, David J. (2020). Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery. Journal of Biological Chemistry, 295 (34), 12143-12152. doi: 10.1074/jbc.ra120.014168

Muratspahić, Edin, Koehbach, Johannes, Gruber, Christian W. and Craik, David J. (2020). Harnessing cyclotides to design and develop novel peptide GPCR ligands. RSC Chemical Biology, 1 (4), 177-191. doi: 10.1039/d0cb00062k

de Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition) anie.202006919. doi: 10.1002/anie.202006919

Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h

Dang, Tien T., Chan, Lai Y., Huang, Yen-Hua, Nguyen, Linh T. T., Kaas, Quentin, Huynh, Tien and Craik, David J. (2020). Exploring the sequence diversity of cyclotides from Vietnamese Viola species. Journal of Natural Products, 83 (6) acs.jnatprod.9b01218, 1817-1828. doi: 10.1021/acs.jnatprod.9b01218

Israel, Mathilde R., Dash, Thomas S., Bothe, Stefanie N., Robinson, Samuel D., Deuis, Jennifer R., Craik, David J., Lampert, Angelika, Vetter, Irina and Durek, Thomas (2020). Characterization of synthetic Tf2 as a NaV1.3 selective pharmacological probe. Biomedicines, 8 (6) 155, 155. doi: 10.3390/biomedicines8060155

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435

Du, Qingdan, Chan, Lai Y., Gilding, Edward K., Henriques, Sónia Troeira, Condon, Nicholas D., Ravipati, Anjaneya S., Kaas, Quentin, Huang, Yen-Hua and Craik, David J. (2020). Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus. Journal of Biological Chemistry, 295 (32), jbc.RA120.012627-10925. doi: 10.1074/jbc.ra120.012627

Yin, Huawu, Huang, Yen-Hua, Deprey, Kirsten, Condon, Nicholas D., Kritzer, Joshua A., Craik, David J. and Wang, Conan K. (2020). Cellular uptake and cytosolic delivery of a cyclic cystine knot scaffold. ACS Chemical Biology, 15 (6), 1650-1661. doi: 10.1021/acschembio.0c00297

Oguis, Georgianna K., Gilding, Edward K., Huang, Yen-Hua, Poth, Aaron G., Jackson, Mark A. and Craik, David J. (2020). Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions. Industrial Crops and Products, 147 112214, 112214. doi: 10.1016/j.indcrop.2020.112214

Agwa, Akello J., Tran, Poanna, Mueller, Alexander, Tran, Hue N. T., Deuis, Jennifer R., Israel, Mathilde R., McMahon, Kirsten L., Craik, David J., Vetter, Irina and Schroeder, Christina I. (2020). Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7. The Journal of Biological Chemistry, 295 (15), 5067-5080. doi: 10.1074/jbc.ra119.012281

Yu, Rilei, Wang, Jiayi, So, Lok-Yan, Harvey, Peta J., Shi, Juan, Liang, Jiazhen, Dou, Qin, Li, Xiao, Yan, Xiayi, Huang, Yen-Hua, Xu, Qingliang, Kaas, Quentin, Chow, Ho-Yin, Wong, Kwok-Yin, Craik, David J, Zhang, Xiaohua, Jiang, Tao and Wang, Yan (2020). Enhanced activity against multi-drug resistant bacteria through coapplication of an analogue of Tachyplesin I and an inhibitor of the QseC/B signaling pathway. Journal of Medicinal Chemistry, 63 (7), 3475-3484. doi: 10.1021/acs.jmedchem.9b01563

Du, Junqiao, Yap, Kuok, Chan, Lai Yue, Rehm, Fabian B. H., Looi, Fong Yang, Poth, Aaron G., Gilding, Edward K., Kaas, Quentin, Durek, Thomas and Craik, David J. (2020). A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors. Nature Communications, 11 (1) 1575, 1-11. doi: 10.1038/s41467-020-15418-2

Kan, Meng-Wei and Craik, David J. (2020). Discovery of cyclotides from Australasian plants. Australian Journal of Chemistry, 73 (4), 287-299. doi: 10.1071/ch19658

Smithies, Bronwyn J., Huang, Yen-Hua, Jackson, Mark A., Yap, Kuok, Gilding, Edward K., Harris, Karen S., Anderson, Marilyn A. and Craik, David J. (2020). Circular permutation of the native enzyme-mediated cyclization position in cyclotides. ACS Chemical Biology, 15 (4) acschembio.9b00996, 962-969. doi: 10.1021/acschembio.9b00996

Tombling, Benjamin J., Wang, Conan K. and Craik, David J. (2020). EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste. Angewandte Chemie, 132 (28) ange.201913809, 11314-11328. doi: 10.1002/ange.201913809

Turner, Ashlin H., Kaas, Quentin, Craik, David J. and Schroeder, Christina I. (2020). Early development of Monoplex pilearis and Monoplex parthenopeus (Gastropoda: Cymatiidae): biology and morphology. Organisms Diversity and Evolution, 20 (1), 51-62. doi: 10.1007/s13127-020-00432-5

Xu, Pan, Kaas, Quentin, Wu, Yong, Zhu, Xiaopeng, Li, Xincan, Harvey, Peta J., Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2020). Structure and activity studies of disulfide-deficient analogues of αO-conotoxin GeXIVA. Journal of Medicinal Chemistry, 63 (4), 1564-1575. doi: 10.1021/acs.jmedchem.9b01409

Hansen, Ida K. Ø., Isaksson, Johan, Poth, Aaron G., Hansen, Kine Ø., Andersen, Aaron J. C., Richard, Céline S. M., Blencke, Hans-Matti, Stensvåg, Klara, Craik, David J. and Haug, Tor (2020). Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens. Marine Drugs, 18 (1) 51, 1-20. doi: 10.3390/md18010051

Li, Choi Yi, Yap, Kuok, Swedberg, Joakim E., Craik, David J. and de Veer, Simon J. (2020). Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b01811, 816-826. doi: 10.1021/acs.jmedchem.9b01811

Lawrence, Nicole, Philippe, Grégoire J.-B., Harvey, Peta J., Condon, Nicholas D., Benfield, Aurélie H., Cheneval, Olivier, Craik, David J. and Troeira Henriques, Sónia (2020). Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells. RSC Chemical Biology, 1 (5), 405-420. doi: 10.1039/d0cb00099j

Troeira Henriques, Sónia, Peacock, Hayden, Benfield, Aurelie, Wang, Conan K and Craik, David J (2019). Is the mirror image a true reflection? Intrinsic membrane chirality modulates peptide binding. Journal of the American Chemical Society, 141 (51) jacs.9b11194, 20460-20469. doi: 10.1021/jacs.9b11194

Tombling, Benjamin J., Wang, Conan K. and Craik, David J. (2019). EGF-like and other disulfide-rich microdomains as therapeutic scaffolds. Angewandte Chemie International Edition, 59 (28), 11218-11232. doi: 10.1002/anie.201913809

Vernen, Felicitas, Craik, David J., Lawrence, Nicole and Troeira Henriques, Sónia (2019). Cyclic analogues of horseshoe crab peptide Tachyplesin I with anticancer and cell penetrating properties. ACS Chemical Biology, 14 (12), 2895-2908. doi: 10.1021/acschembio.9b00782

de Veer, Simon J., Kan, Meng-Wei and Craik, David J. (2019). Cyclotides: from structure to function. Chemical Reviews, 119 (24) acs.chemrev.9b00402, 12375-12421. doi: 10.1021/acs.chemrev.9b00402

Bleackley, Mark R., Dawson, Charlotte S., Payne, Jennifer A.E., Harvey, Peta J., Rosengren, K. Johan, Quimbar, Pedro, Garcia-Ceron, Donovan, Lowe, Rohan, Bulone, Vincent, van der Weerden, Nicole L, Craik, David J. and Anderson, Marilyn A. (2019). The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins. The Cell Surface, 5 100026, 100026. doi: 10.1016/j.tcsw.2019.100026

Huang, Yen-Hua, Du, Qingdan and Craik, David J. (2019). Cyclotides: disulfide-rich peptide toxins in plants. Toxicon, 172, 33-44. doi: 10.1016/j.toxicon.2019.10.244

Rehm, Fabian B. H., Harmand, Thibault J., Yap, Kuok, Durek, Thomas, Craik, David J. and Ploegh, Hidde L. (2019). Site-specific sequential protein labeling catalyzed by a single recombinant ligase. Journal of the American Chemical Society, 141 (43) jacs.9b09166, 17388-17393. doi: 10.1021/jacs.9b09166

Jin, Ai-Hua, Muttenthaler, Markus, Dutertre, Sebastien, Himaya, S.W.A., Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2019). Conotoxins: chemistry and biology. Chemical Reviews, 119 (21), 11510-11549. doi: 10.1021/acs.chemrev.9b00207

Sang, Jianrong, Kulkarni, Ketav, Watson, Gabrielle M., Ma, Xiuquan, Craik, David J., Henriques, Sónia T., Poth, Aaron G., Benfield, Aurélie H. and Wilce, Jacqueline A. (2019). Evaluation of cyclic peptide inhibitors of the Grb7 breast cancer target: small change in cargo results in large change in cellular activity. Molecules, 24 (20) 3739, 3739. doi: 10.3390/molecules24203739

Ma, He, Qiu, Peiju, Harvey, Peta J., Li, Xiao, Zhang, Zheyu, Xu, Qingliang, Liang, Jiazhen, Kaas, Quentin, Craik, David J., Yang, Jinbo, Jiang, Tao, Bi, Xiaolin and Yu, Rilei (2019). In Silico design of MDM2-targeting peptides from a naturally occurring constrained peptide. Chemmedchem, 14 (19) cmdc.201900366, 1710-1716. doi: 10.1002/cmdc.201900366

Oshiro, Karen G. N., Cândido, Elizabete S., Chan, Lai Y., Torres, Marcelo D. T., Monges, Bruna E. D., Rodrigues, Silvia G., Porto, William F., Ribeiro, Suzana M., Henriques, Sónia T., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2019). Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties. Journal of Medicinal Chemistry, 62 (17), 8140-8151. doi: 10.1021/acs.jmedchem.9b00915

Vernen, Felicitas, Harvey, Peta J., Dias, Susana A., Veiga, Ana Salomé, Huang, Yen-Hua, Craik, David J., Lawrence, Nicole and Troeira Henriques, Sónia (2019). Characterization of tachyplesin peptides and their cyclized analogues to improve antimicrobial and anticancer properties. International Journal of Molecular Sciences, 20 (17) 4184, 4184. doi: 10.3390/ijms20174184

Philippe, Grégoire J. -B., Gaspar, Diana, Sheng, Caibin, Huang, Yen-Hua, Benfield, Aurélie H., Condon, Nicholas D., Weidmann, Joachim, Lawrence, Nicole, Löwer, Alexander, Castanho, Miguel A. R. B., Craik, David J. and Troeira Henriques, Sónia (2019). Cell membrane composition drives selectivity and toxicity of designed cyclic helix-loop-helix peptides with cell penetrating and tumor suppressor properties. ACS Chemical Biology, 14 (9), 2071-2087. doi: 10.1021/acschembio.9b00593

Harris, Karen S., Guarino, Rosemary F., Dissanayake, Ravindu S., Quimbar, Pedro, McCorkelle, Owen C., Poon, Simon, Kaas, Quentin, Durek, Thomas, Gilding, Edward K., Jackson, Mark A., Craik, David J., van der Weerden, Nicole L., Anders, Robin F. and Anderson, Marilyn A. (2019). A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein. Scientific Reports, 9 (1) 10820, 10820. doi: 10.1038/s41598-019-47273-7

Tian, Sixin, Swedberg, Joakim E., Li, Choi Yi, Craik, David J. and de Veer, Simon J. (2019). Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3. ACS Medicinal Chemistry Letters, 10 (8) acsmedchemlett.9b00253, 1234-1239. doi: 10.1021/acsmedchemlett.9b00253

Cândido, Elizabete S., Cardoso, Marlon H., Chan, Lai Y., Torres, Marcelo D. T., Oshiro, Karen G. N., Porto, William F., Ribeiro, Suzana M., Haney, Evan F., Hancock, Robert E. W., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2019). Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential. ACS Infectious Diseases, 5 (7) acsinfecdis.9b00073, 1081-1086. doi: 10.1021/acsinfecdis.9b00073

Koehbach, Johannes and Craik, David J. (2019). The vast structural diversity of antimicrobial peptides. Trends in Pharmacological Sciences, 40 (7), 517-528. doi: 10.1016/j.tips.2019.04.012

Poth, Aaron G., Huang, Yen-Hua, Le, Thao T., Kan, Meng-Wei and Craik, David J. (2019). Pharmacokinetic characterization of kalata B1 and related therapeutics built on the cyclotide scaffold. International Journal of Pharmaceutics, 565, 437-446. doi: 10.1016/j.ijpharm.2019.05.001

Schmidt, Marcel, Huang, Yen-Hua, de Oliveira, Eduardo F. Texeira, Toplak, Ana, Wijma, Hein J., Janssen, Dick B., van Maarseveen, Jan H., Craik, David J. and Nuijens, Timo (2019). Efficient enzymatic cyclization of disulfide-rich peptides by using peptide ligases. ChemBioChem, 20 (12) cbic.201900033, 1524-1529. doi: 10.1002/cbic.201900033

Yin, Huawu, Craik, David J. and Wang, Conan K. (2019). Anchor residues guide form and function in grafted peptides. Angewandte Chemie International Edition, 58 (23), 7652-7656. doi: 10.1002/anie.201901572

Nicolas, Sebastien, Zoukimian, Claude, Bosmans, Frank, Montnach, Jerome, Diochot, Sylvie, Cuypers, Eva, De Waard, Stephan, Beroud, Remy, Mebs, Dietrich, Craik, David, Boturyn, Didier, Lazdunski, Michel, Tytgat, Jan and De Waard, Michel (2019). Chemical synthesis, proper folding, Na-v channel selectivity profile and analgesic properties of the spider peptide phlotoxin 1. Toxins, 11 (6) 367, 367. doi: 10.3390/toxins11060367

Yin, Huawu, Craik, David J. and Wang, Conan K. (2019). Anchor residues guide form and function in grafted peptides. Angewandte Chemie, 131 (23), 7734-7738. doi: 10.1002/ange.201901572

Chambers, Chris, Cutler, Penny, Huang, Yen-Hua, Goodchild, James A., Blythe, Judith, Wang, Conan K., Bigot, Aurélien, Kaas, Quentin, Craik, David J., Sabbadin, Davide and Earley, Fergus G. (2019). Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor. FEBS Letters, 593 (12) 1873-3468.13435, 1336-1350. doi: 10.1002/1873-3468.13435

El Hamdaoui, Yamina, Wu, Xiaosa, Clark, Richard J., Giribaldi, Julien, Anangi, Raveendra, Craik, David J., King, Glenn F., Dutertre, Sebastien, Kaas, Quentin, Herzig, Volker and Nicke, Annette (2019). Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR. Frontiers in Pharmacology, 10 (MAY) 577, 577. doi: 10.3389/fphar.2019.00577

Oguis, Georgianna K., Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2019). Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine. Frontiers in Plant Science, 10 645, 645. doi: 10.3389/fpls.2019.00645

Jackson, Mark A., Yap, Kuok, Poth, Aaron G., Gilding, Edward K., Swedberg, Joakim E., Poon, Simon, Qu, Haiou, Durek, Thomas, Harris, Karen, Anderson, Marilyn A. and Craik, David J. (2019). Rapid and scalable plant-based production of a potent plasmin inhibitor peptide. Frontiers in Plant Science, 10 602, 602. doi: 10.3389/fpls.2019.00602

Israel, Mathilde R., Tanaka, Brian S., Castro, Joel, Thongyoo, Panumart, Robinson, Samuel D., Zhao, Peng, Deuis, Jennifer R., Craik, David J., Durek, Thomas, Brierley, Stuart M., Waxman, Stephen G, Dib-Hajj, Sulayman D. and Vetter, Irina (2019). NaV1.6 regulates excitability of mechanosensitive sensory neurons. Journal of Physiology, 597 (14), 3751-3768. doi: 10.1113/JP278148

Yu, Rilei, Tae, Han‐Shen, Xu, Qingliang, Craik, David J., Adams, David J., Jiang, Tao and Kaas, Quentin (2019). Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British Journal of Pharmacology, 176 (15) bph.14698, 2750-2763. doi: 10.1111/bph.14698

Kerenga, Bomai K., McKenna, James A., Harvey, Peta J., Quimbar, Pedro, Garcia-Ceron, Donovan, Lay, Fung T., Thanh Kha Phan,, Veneer, Prem K., Vasa, Shaily, Parisi, Kathy, Shafee, Thomas M. A., van der Weerden, Nicole L., Hulett, Mark D., Craik, David J., Anderson, Marilyn A. and Bleackley, Mark R. (2019). Salt-tolerant antifungal and antibacterial activities of the corn defensin ZmD32. Frontiers in Microbiology, 10 795, 795. doi: 10.3389/fmicb.2019.00795

Rehm, Fabian B. H., Jackson, Mark A., De Geyter, Ewout, Yap, Kuok, Gilding, Edward K., Durek, Thomas and Craik, David J. (2019). Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization. Proceedings of the National Academy of Sciences, 116 (16), 7831-7836. doi: 10.1073/pnas.1901807116

Li, Choi Yi, de Veer, Simon J., White, Andrew M., Chen, Xingchen, Harris, Jonathan M., Swedberg, Joakim E. and Craik, David J. (2019). Amino acid scanning at P5′ within the Bowman–Birk inhibitory loop reveals specificity trends for diverse serine proteases. Journal of Medicinal Chemistry, 62 (7), 3696-3706. doi: 10.1021/acs.jmedchem.9b00211

Wang, Conan K. and Craik, David J. (2019). Toward structure determination of disulfide-rich peptides using chemical shift-based methods. The Journal of Physical Chemistry B, 123 (9) acs.jpcb.8b10649, 1903-1912. doi: 10.1021/acs.jpcb.8b10649

Peigneur, Steve, Cheneval, Olivier, Maiti, Mohitosh, Leipold, Enrico, Heinemann, Stefan H., Lescrinier, Eveline, Herdewijn, Piet, De Lima, Maria Elena, Craik, David J., Schroeder, Christina I. and Tytgat, Jan (2019). Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors. FASEB Journal, 33 (3), 3693-3703. doi: 10.1096/fj.201801909R

Dash, Thomas S., Shafee, Thomas, Harvey, Peta J., Zhang, Chuchu, Peigneur, Steve, Deuis, Jennifer R., Vetter, Irina, Tytgat, Jan, Anderson, Marilyn A., Craik, David J., Durek, Thomas and Undheim, Eivind A. B. (2019). A centipede toxin family defines an ancient class of CSαβ defensins. Structure, 27 (2), 315-326. doi: 10.1016/j.str.2018.10.022

Swedberg, Joakim E., Wu, Guojie, Mahatmanto, Tunjung, Durek, Thomas, Caradoc-Davies, Tom T., Whisstock, James C., Law, Ruby H. P. and Craik, David J. (2019). Highly potent and selective plasmin inhibitors based on the sunflower trypsin inhibitor-1 scaffold attenuate fibrinolysis in plasma. Journal of Medicinal Chemistry, 62 (2), 552-560. doi: 10.1021/acs.jmedchem.8b01139

Du, Junqiao, Chan, Lai Yue, Poth, Aaron G. and Craik, David J. (2019). Discovery and characterization of cyclic and acyclic trypsin inhibitors from Momordica dioica. Journal of Natural Products, 82 (2) acs.jnatprod.8b00716, 293-300. doi: 10.1021/acs.jnatprod.8b00716

Li, Choi Yi, de Veer, Simon J., Law, Ruby H. P., Whisstock, James C., Craik, David J. and Swedberg, Joakim E. (2019). Characterising the subsite specificity of urokinase-type plasminogen activator and tissue-type plasminogen activator using a sequence-defined peptide aldehyde library. ChemBioChem, 19 (1), 46-50. doi: 10.1002/cbic.201800395

Silva, Osmar N., Pinto, Michelle F. S., Viana, Juliane F. C., Freitas, Camila G., Fensterseifer, Isabel C. M., Craik, David J. and Franco, Octavio L. (2019). Evaluation of the in vitro antitumor activity of nanostructured cyclotides in polymers of Eudragit (R) L 100-55 and RS 30 D. Letters in Drug Design and Discovery, 16 (4), 437-445. doi: 10.2174/1570180815666180801115526

Pérez-Peinado, Clara, Almeida Dias, Susana, Domingues, Marco M., Benfield, Aurélie H., Freire, João Miguel, Radis-Baptista, Gandhi, Gaspar, Diana, Castanho, Miguel A. R. B., Craik, David J., Henriques, Sonia Troeira, Veiga, Ana S. and Andreu, David (2018). Mechanism of bacterial membrane permeabilization of crotalicidin (Ctn) and its fragment Ctn[15-34], antimicrobial peptides from rattlesnake venom. The Journal of Biological Chemistry, 293 (5), 1536-1549. doi: 10.1074/jbc.RA117.000125

Swedberg, Joakim E., Ghani, Hafiza Abdul, Harris, Jonathan M., de Veer, Simon J. and Craik, David J. (2018). Potent, selective, and cell-penetrating inhibitors of Kallikrein-related peptidase 4 based on the cyclic peptide MCoTI-II. ACS Medicinal Chemistry Letters, 9 (12) acsmedchemlett.8b00422, 1258-1262. doi: 10.1021/acsmedchemlett.8b00422

Lawrence, Nicole, Wu, Bin, Ligutti, Joseph, Cheneval, Olivier, Agwa, Akello Joanna, Benfield, Aurélie H., Biswas, Kaustav, Craik, David J., Miranda, Les P., Henriques, Sónia Troeira and Schroeder, Christina I. (2018). Peptide-membrane interactions affect the inhibitory potency and selectivity of spider toxins ProTx-II and GpTx-1. ACS Chemical Biology, 14 (1) acschembio.8b00989, 118-130. doi: 10.1021/acschembio.8b00989

Ramalho, Suelem D., Wang, Conan K., King, Gordon J., Byriel, Karl A., Huang, Yen-Hua, Bolzani, Vanderlan S. and Craik, David J. (2018). Synthesis, racemic x-ray crystallographic, and permeability studies of bioactive orbitides from Jatropha species. Journal of Natural Products, 81 (11) acs.jnatprod.8b00447, 2436-2445. doi: 10.1021/acs.jnatprod.8b00447

Niyomploy, Ploypat, Chan, Lai Yue, Harvey, Peta J., Poth, Aaron G., Colgrave, Michelle L. and Craik, David J. (2018). Discovery and characterization of cyclotides from Rinorea species. Journal of Natural Products, 81 (11) acs.jnatprod.8b00572, 2512-2520. doi: 10.1021/acs.jnatprod.8b00572

Yu, Jinpeng, Zhu, Xiaopeng, Harvey, Peta J., Kaas, Quentin, Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2018). Single amino acid substitution in α-conotoxin TxID reveals a specific α3β4 nicotinic acetylcholine receptor antagonist. Journal of Medicinal Chemistry, 61 (20), 9256-9265. doi: 10.1021/acs.jmedchem.8b00967

Harvey, Peta J., Kurniawan, Nyoman D., Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Van Lysebetten, Dorien, Dash, Thomas S., Hill, Justine M., Adams, David J., Durek, Thomas and Craik, David J. (2018). NMR structure of µ-conotoxin GIIIC: Leucine 18 induces local repacking of the N-terminus resulting in reduced Nav channel potency. Molecules, 23 (10) molecules23102715. doi: 10.3390/molecules23102715

Cardoso, Marlon, Cândido, Elizabete, Chan, Lai, Torres, Marcelo Der Torossian, Oshiro, Karen, Rezende, Samilla, Porto, William F., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2018). A computationally designed peptide derived from Escherichia coli as a potential drug template for antibacterial and antibiofilm therapies. ACS Infectious Diseases, 4 (12) acsinfecdis.8b00219, 1727-1736. doi: 10.1021/acsinfecdis.8b00219

Kwon, Soohyun, Duarte, Joao N., Li, Zeyang, Ling, Jingjing J., Cheneval, Olivier, Durek, Thomas, Schroeder, Christina I., Craik, David J. and Ploegh, Hidde L. (2018). Targeted delivery of cyclotides via conjugation to a nanobody. ACS Chemical Biology, 13 (10), 2973-2980. doi: 10.1021/acschembio.8b00653

Agwa, Akello J., Blomster, Linda V., Craik, David J., King, Glenn F. and Schroeder, Christina I. (2018). Efficient enzymatic ligation of inhibitor cystine knot spider venom peptides: using sortase a to form double-knottins that probe voltage-gated sodium channel NaV1.7. Bioconjugate Chemistry, 29 (10) acs.bioconjchem.8b00505, 3309-3319. doi: 10.1021/acs.bioconjchem.8b00505

Hone, Arik J., Talley, Todd T, Bobango, Janet, Huidobro Melo, Cesar, Hararah, Fuaad, Gajewiak, Joanna B., Christensen, Sean B, Harvey, Peta J., Craik, David J. and McIntosh, J. Michael (2018). Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 293 (46), 17838-17852. doi: 10.1074/jbc.ra118.005649

Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J., Craik, David J. and Kaas, Quentin (2018). Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology, 155, 288-297. doi: 10.1016/j.bcp.2018.07.007

de Veer, Simon J., Li, Choi Yi, Swedberg, Joakim E., Schroeder, Christina I. and Craik, David J. (2018). Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. European Journal of Medicinal Chemistry, 155, 695-704. doi: 10.1016/j.ejmech.2018.06.029

Lawrence, Nicole, Dennis, Adelaide S. M., Lehane, Adele M., Ehmann, Anna, Harvey, Peta J., Benfield, Aurélie H., Cheneval, Olivier, Henriques, Sónia Troeira, Craik, David J. and McMorran, Brendan J. (2018). Defense peptides engineered from human platelet factor 4 kill Plasmodium by selective membrane disruption. Cell Chemical Biology, 25 (9), 1140-+. doi: 10.1016/j.chembiol.2018.06.009

Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9

Wang, Conan K., Ghani, Hafiza Abdul, Bundock, Anna, Weidmann, Joachim, Harvey, Peta J., Edwards, Ingrid A., Schroeder, Christina I., Swedberg, Joakim E. and Craik, David J. (2018). Calcium-mediated allostery of the EGF fold. ACS Chemical Biology, 13 (6), 1659-1667. doi: 10.1021/acschembio.8b00291

Sadeghi, Mahsa, Carstens, Bodil B., Callaghan, Brid P., Daniel, James T., Tae, Han Shen, O'Donnell, Tracey, Castro, Joel, Brierley, Stuart M., Adams, David J., Craik, David J. and Clark, Richard J. (2018). Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. ACS Chemical Biology, 13 (6), 1577-1587. doi: 10.1021/acschembio.8b00190

Craik, David J. and Payne, Richard J. (2018). Emerging peptide science in Australia. Peptide Science, 110 (3) e24080, e24080. doi: 10.1002/pep2.24080

Agwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553

Wang, Conan K. and Craik, David J. (2018). Designing macrocyclic disulfide-rich peptides for biotechnological applications. Nature Chemical Biology, 14 (5), 417-427. doi: 10.1038/s41589-018-0039-y

Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018). Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 (8), 3674-3684. doi: 10.1021/acs.jmedchem.8b00170

Turner, Ashlin H., Craik, David J., Kaas, Quentin and Schroeder, Christina I. (2018). Bioactive compounds isolated from neglected predatory marine gastropods. Marine Drugs, 16 (4) 118, 118. doi: 10.3390/md16040118

Castro, Joel, Grundy, Luke, Deiteren, Annemie, Harrington, Andrea M., O'Donnell, Tracey, Maddern, Jessica, Moore, Jessi, Garcia-Caraballo, Sonia, Rychkov, Grigori Y., Yu, Rilei, Kaas, Quentin, Craik, David J., Adams, David J. and Brierley, Stuart M. (2018). Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology, 175 (12), 2384-2398. doi: 10.1111/bph.14115

Wang, Conan K., Swedberg, Joakim E., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2018). Conformational Flexibility Is a Determinant of Permeability for Cyclosporin. The Journal of Physical Chemistry. B, 122 (8), 2261-2276. doi: 10.1021/acs.jpcb.7b12419

Israel, Mathilde R., Thongyoo, Panumart, Deuis, Jennifer R., Craik, David J., Vetter, Irina and Durek, Thomas (2018). The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6. Journal of Medicinal Chemistry, 61 (4), 1730-1736. doi: 10.1021/acs.jmedchem.7b01609

Poon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422

Durek, Thomas, Shelukhina, Irina V., Tae, Han-Shen, Thongyoo, Panumart, Spirova, Ekaterina N., Kudryavtsev, Denis S., Kasheverov, Igor E., Faure, Grazyna, Corringer, Pierre-Jean, Craik, David J., Adams, David J. and Tsetlin, Victor I. (2017). Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports, 7 (1) 16606, 16606. doi: 10.1038/s41598-017-16809-0

Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sonia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017). Biochimica Et Biophysica Acta-Biomembranes, 1859 (11), 2277-2277. doi: 10.1016/j.bbamem.2017.08.008

Ojeda, Paola G. , Henriques, Sonia Troeira, Pan, Yijun, Nicolazzo, Joseph A., Craik, David J. and Wang, Conan K. (2017). Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake. Biopolymers, 108 (5) e23025, e23025. doi: 10.1002/bip.23025

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386

Agwa, Akello J., Huang, Yen-Hua, Craik, David J., Henriques, Sonia T. and Schroeder, Christina I. (2017). Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins. Toxins, 9 (8) 248, 248. doi: 10.3390/toxins9080248

Craik, David J., Lee, Meng-Han, Rehm, Fabian B.H., Tombling, Benjamin, Doffek, Benjamin and Peacock, Hayden (2017). Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic and Medicinal Chemistry, 26 (10), 2727-2737. doi: 10.1016/j.bmc.2017.08.005

Henriques, Sónia Troeira, Lawrence, Nicole, Chaousis, Stephanie, Ravipati, Anjaneya S., Cheneval, Olivier, Benfield, Aurélie H., Elliott, Alysha G., Kavanagh, Angela Maria, Cooper, Matthew A., Chan, Lai Yue, Huang, Yen-Hua and Craik, David J. (2017). Redesigned spider peptide with improved antimicrobial and anticancer properties. ACS Chemical Biology, 12 (9), 2324-2334. doi: 10.1021/acschembio.7b00459

Wu, Yong, Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Zhangsun, Manqi, Harvey, Peta J., Craik, David J., McIntosh, J. Michael and Luo, Sulan (2017). α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry, 60 (13), 5826-5833. doi: 10.1021/acs.jmedchem.7b00546

Cranfield, Charles G., Henriques, Sonia Troeira, Martinac, Boris, Duckworth, Paul, Craik, David J. and Cornell, Bruce (2017). Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes. Langmuir, 33 (26), 6630-6637. doi: 10.1021/acs.langmuir.7b01642

de Veer, Simon J., Weidmann, Joachim and Craik, David J. (2017). Cyclotides as tools in chemical biology. Accounts of Chemical Research, 50 (7), 1557-1565. doi: 10.1021/acs.accounts.7b00157

Craik, David J. and Henriques, Sonia Troeira (2017). Editorial overview. Current Opinion in Chemical Biology, 38, iv-vi. doi: 10.1016/j.cbpa.2017.05.012

Craik, David J. and Du, Junqiao (2017). Cyclotides as drug design scaffolds. Current Opinion in Chemical Biology, 38, 8-16. doi: 10.1016/j.cbpa.2017.01.018

Ravipati, Anjaneya S., Poth, Aaron G., Henriques, Sonia Troeira, Bhandari, Murari, Huang, Yen-Hua, Nino, Jaime, Colgrave, Michelle L. and Craik, David J. (2017). Understanding the diversity and distribution of cyclotides from plants of varied genetic origin. Journal of Natural Products, 80 (5), 1522-1530. doi: 10.1021/acs.jnatprod.7b00061

Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sónia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochimica et Biophysica Acta. Biomembranes, 1859 (5), 835-844. doi: 10.1016/j.bbamem.2017.01.020

Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Wu, Yong, Craik, David J. , McIntosh, J. Michael and Luo, Sulan (2017). αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype. Neuropharmacology, 127, 243-252. doi: 10.1016/j.neuropharm.2017.04.015

Kubota, Tomoya, Durek, Thomas, Dang, Bobo, Finol-Urdaneta, Rocio K., Craik, David J., Kent, Stephen B. H., French, Robert J., Bezanilla, Francisco and Correa, Ana M. (2017). Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences, 114 (10), E1857-E1865. doi: 10.1073/pnas.1700453114

Grage, Stephan L., Sani, Marc-Antoine, Cheneval, Olivier, Henriques, Sonia Troeira, Schalck, Constantin, Heinzmann, Ralf, Mylne, Joshua S., Mykhailiuk, Pavel K., Afonin, Sergii, Komarov, Igor V., Separovic, Frances, Craik, David J. and Ulrich, Anne S. (2017). Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR. Biophysical Journal, 112 (4), 630-642. doi: 10.1016/j.bpj.2016.12.040

Troeira Henriques, Sonia and Craik, David J. (2017). Cyclotide structure and function: the role of membrane binding and permeation. Biochemistry, 56 (5), 669-682. doi: 10.1021/acs.biochem.6b01212

Qu, Haiou, Smithies, Bronwyn J. , Durek, Thomas and Craik, David J. (2017). Synthesis and protein engineering applications of cyclotides. Australian Journal of Chemistry, 70 (2), 152-161. doi: 10.1071/CH16589

Swedberg, Joakim E., Li, Choi Yi, De Veer, Simon J., Wang, Conan K. and Craik, David J. (2017). Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold. Journal of Medicinal Chemistry, 60 (2), 658-667. doi: 10.1021/acs.jmedchem.6b01509

Verbandt, Sara, Henriques, Sónia Troeira, Spincemaille, Pieter, Harvey, Peta J., Chandhok, Gursimran, Sauer, Vanessa, De Coninck, Barbara, Cassiman, David, Craik, David J., Cammue, Bruno P. A., De Cremer, Kaat and Thevissen, Karin (2017). Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells. Mechanisms of Ageing and Development, 161 (B), 247-254. doi: 10.1016/j.mad.2016.07.013

Abdul Ghani, Hafiza, Henriques, Sonia Troeira, Huang, Yen-Hua, Swedberg, Joakim E. , Schroeder, Christina I. and Craik, David J. (2017). Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies. Biopolymers, 108 (1) e22927. doi: 10.1002/bip.22927

Matsuura, Helio N., Poth, Aaron G., Yendo, Anna C. A., Fett-Neto, Arthur G. and Craik, David J. (2016). Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids. Journal of Natural Products, 79 (12), 3006-3013. doi: 10.1021/acs.jnatprod.6b00492

White, Andrew M. and Craik, David J. (2016). Discovery and optimization of peptide macrocycles. Expert Opinion on Drug Discovery, 11 (12), 1151-1163. doi: 10.1080/17460441.2016.1245720

Pinto, Michelle F. S., Silva, Osmar N., Viana, Juilan C., Porto, William F., Migliolo, Ludovico, da Cunha, Nicolau B., Gomes Jr., Nelson, Fensterseifer, Isabel C. M., Colgrave, Michelle L., Craik, David J., Dias, Simoni C. and Franco, Octavio L. (2016). Characterization of a bioactive acyclotide from Palicourea rigida. Journal of Natural Products, 79 (11), 2767-2773. doi: 10.1021/acs.jnatprod.6b00270

Craik, David J. and Wang, Conan K. (2016). Forward for ICCP2015 issue of biopolymers peptide science. Biopolymers, 106 (6), 772-773. doi: 10.1002/bip.22989

Carstens, Bodil B., Swedberg, Joakim, Berecki, Geza, Adams, David J., Craik, David J. and Clark, Richard J. (2016). Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers, 106 (6), 864-875. doi: 10.1002/bip.22848

Niyomploy, Ploypat, Chan, Lai Yue, Poth, Aaron G., Colgrave, Michelle L., Sangvanich, Polkit and Craik, David J. (2016). Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miq. Biopolymers, 106 (6), 796-805. doi: 10.1002/bip.22914

Wang, Conan K. and Craik, David J. (2016). Cyclic peptide oral bioavailability: lessons from the past. Biopolymers, 106 (6), 901-909. doi: 10.1002/bip.22878

Chan, LaiYue, Craik, David J. and Daly, Norelle L. (2016). Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy. Scientific Reports, 6 (1) 35347, 35347. doi: 10.1038/srep35347

Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016). Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 (10), 2202-2212. doi: 10.1002/bit.25993

Bleackley, Mark R., Payne, Jennifer A. E., Hayes, Brigitte M. E, Durek, Thomas, Craik, David J., Shafee, Thomas M. A., Poon, Ivan K. H., Hulett, Mark D., Van Der Weerden, Nicole L. and Anderson, Marilyn A. (2016). Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant. Antimicrobial Agents and Chemotherapy, 60 (10), 6302-6312. doi: 10.1128/AAC.01479-16

Daly, Norelle L., Gunasekera, Sunithi, Clark, Richard J., Lin, Feng, Wade, John D., Anderson, Marilyn and Craik, David J. (2016). The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers, 106 (6), 825-833. doi: 10.1002/bip.22977

Craik, David J., Youn Young Shim, Goransson, Ulf, Moss, Gerard P., Tan, Ninghua, Jadhav, Pramodkumar D., Shen, Jianheng and Reaney, Martin J. T. (2016). Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim report. Biopolymers, 106 (6), 917-924. doi: 10.1002/bip.22939

Sable, Rushikesh, Durek, Thomas, Taneja, Veena, Craik, David J., Pallerla, Sandeep, Gauthier, Ted and Jois, Seetharama (2016). Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interaction. ACS Chemical Biology, 11 (8), 2366-2374. doi: 10.1021/acschembio.6b00486

Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095

Swedberg, Joakim E., Mahatmanto, Tunjung, Ghani, Hafiza Abdul, de Veer, Simon J., Schroeder, Christina I., Harris, Jonathan M. and Craik, David J. (2016). Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffold. Journal of Medicinal Chemistry, 59 (15), 7287-7292. doi: 10.1021/acs.jmedchem.6b00557

Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Price, David A., Liras, Spiros and Craik, David J. (2016). Truncated glucagon-like peptide-1 and exendin-4 α-conotoxin pl14a peptide chimeras maintain potency and α-helicity and reveal interactions vital for cAMP signaling in vitro. Journal of Biological Chemistry, 291 (30), 15778-15787. doi: 10.1074/jbc.M116.724542

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016). European Journal of Organic Chemistry, 2016 (21), 3457-3457. doi: 10.1002/ejoc.201670211

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Cyclisation of disulfide-rich conotoxins in drug design applications. European Journal of Organic Chemistry, 2016 (21), 3462-3472. doi: 10.1002/ejoc.201600402

Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016). Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 (22), 11829-11842. doi: 10.1074/jbc.M116.721662

Weidmann, Joachim and Craik, David J. (2016). Discovery, structure, function, and applications of cyclotides: circular proteins from plants. Journal of Experimental Botany, 67 (16), 4801-4812. doi: 10.1093/jxb/erw210

Wang, Conan K., Stalmans, Sofie, De Spiegeleer, Bart and Craik, David J. (2016). Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold. Journal of Peptide Science, 22 (5), 305-310. doi: 10.1002/psc.2862

Wang, Conan K., King, Gordon J., Conibear, Anne C., Ramos, Mariana C., Chaousis, Stephanie, Henriques, Sonia Troeira and Craik, David J. (2016). Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties. Journal of American Chemical Society, 138 (17), 5706-5713. doi: 10.1021/jacs.6b02575

Carstens, Bodil B., Berecki, Géza, Daniel, James T., Lee, Han Siean, Jackson, Kathryn A. V., Tae, Han-Shen, Sadeghi, Mahsa, Castro, Joel, O'Donnell, Tracy, Deiteren, Annemie, Brierley, Stuart M., Craik, David J., Adams, David J. and Clark, Richard J. (2016). Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie, 128 (15), 4770-4774. doi: 10.1002/ange.201600297

Castro, Joel, Harrington, Andrea M., Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E., Craik, David J., Adams, David J. and Brierley, Stuart M. (2016). α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut, 66 (6), 1083-1094. doi: 10.1136/gutjnl-2015-310971

Wang, Conan K., Northfield, Susan E., Huang, Yen-Hua, Ramos, Mariana C. and Craik, David J. (2016). Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold. European Journal of Medicinal Chemistry, 109, 342-349. doi: 10.1016/j.ejmech.2016.01.006

Deplazes, Evelyne, Troeira Henriques, Sonia, Smith, Jennifer J., King, Glenn F., Craik, David J., Mark, Alan E. and Schroeder, Christina I. (2016). Membrane-binding properties of gating modifier and pore-blocking toxins: membrane interaction is not a prerequisite for modification of channel gating. Biochimica et Biophysica Acta - Biomembranes, 1858 (4), 872-882. doi: 10.1016/j.bbamem.2016.02.002

Ojeda, Paola G., Wang, Conan K. and Craik, David J. (2016). Chlorotoxin: structure, activity, and potential uses in cancer therapy. Biopolymers - Peptide Science, 106 (1), 25-36. doi: 10.1002/bip.22748

Conibear, Anne C., Chaousis, Stephanie, Durek, Thomas, Rosengren, K. Johan, Craik, David J. and Schroeder, Christina I. (2016). Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization. Biopolymers, 106 (1), 89-100. doi: 10.1002/bip.22767

D'Souza, Charlotte, Henriques, Sonia Troeira, Wang, Conana K., Cheneval, Olivier, Chan, Lai Yue, Bokil, Nilesh J., Sweet, Matthew J. and Craik, David J. (2016). Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer. Biochemistry, 55 (2), 396-405. doi: 10.1021/acs.biochem.5b00529

Elliott, Alysha G., Franke, Bastian, Armstrong, David A., Craik, David J., Mylne, Joshua S. and Rosengren, K. Johan (2016). Natural structural diversity within a conserved cyclic peptide scaffold. Amino Acids, 49 (1), 1-14. doi: 10.1007/s00726-016-2333-x

Vriens, Kim, Cools, Tanne L., Harvey, Peta J., Craik, David J., Braem, Annabel, Vleugels, Jozef, Coninck, Barbara De, Cammue, Bruno P. A. and Thevissen, Karin (2016). The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms. Peptides, 75, 71-79. doi: 10.1016/j.peptides.2015.11.001

Carstens, Bodil B., Berecki, Geza, Daniel, James T., Lee, Han Siean, Jackson, Kathryn A. V., Tae, Han-Shen, Sadeghi, Mahsa, Castro, Joel, O'Donnell, Tracy, Deiteren, Annemie, Brierley, Stuart M., Craik, David J., Adams, David J. and Clark, Richard J. (2016). Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie - International Edition, 55 (15), 4692-4696. doi: 10.1002/anie.201600297

Philippe, Gregoire, Huang, Yen-Hua, Cheneval, Olivier, Lawrence, Nicole, Zhang, Zhen, Fairlie, David P., Craik, David J., Dantas De Araujo, Aline and Troeira Henriques, Sonia (2016). Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions. Biopolymers - Peptide Science, 106 (6), 853-863. doi: 10.1002/bip.22893

Wang, Conan K., Swedberg, Joakim E., Northfield, Susan E. and Craik, David J. (2015). Effects of Cyclization on Peptide Backbone Dynamics. Journal of Physical Chemistry B, 119 (52), 15821-15830. doi: 10.1021/acs.jpcb.5b11085

Harris, Karen S., Durek, Thomas, Kaas, Quentin, Poth, Aaron G., Gilding, Edward K., Conlan, Brendon F., Saska, Ivana, Daly, Norelle L., Van Der Weerden, Nicole L., Craik, David J. and Anderson, Marilyn A. (2015). Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase. Nature Communications, 6 (10199) 10199, 10199. doi: 10.1038/ncomms10199

Gilding, Edward K., Jackson, Mark A., Poth, Aaron G., Henriques, Sonia Troeira, Prentis, Peter J., Mahatmanto, Tunjung and Craik, David J. (2015). Gene coevolution and regulation lock cyclic plant defence peptides to their targets. New Phytologist, 210 (2), 717-730. doi: 10.1111/nph.13789

Akcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Mari, Frank and Craik, David J. (2015). Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Peptide Science, 104 (6), 682-692. doi: 10.1002/bip.22699

Chan, Lai Yue, Craik, David J. and Daly, Norelle L. (2015). Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration. Bioscience Reports, 35 (6) e00270, e00270-e00270. doi: 10.1042/BSR20150210

Craik, David J. (2015). Preface. Plant Cyclotides, 76, XI-XIII. doi: 10.1016/S0065-2296(15)00118-4

Ravipati, Anjaneya S., Henriques, Sónia Troeira, Poth, Aaron G., Kaas, Quentin, Wang, Conan K., Colgrave, Michelle L. and Craik, David J. (2015). Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae. ACS Chemical Biology, 10 (11), 2491-2500. doi: 10.1021/acschembio.5b00454

Burman, Robert, Yeshak, Mariamawit Y., Larsson, Sonny, Craik, David J., Rosengren, K. Johan and Goeransson, Ulf (2015). Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae. Frontiers in Plant Science, 6 (855) 855, 1-13. doi: 10.3389/fpls.2015.00855

Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Durek, Thomas, Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Liras, Spiros, Price, David A. and Craik, David J. (2015). Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists. European Journal of Medicinal Chemistry, 103, 175-184. doi: 10.1016/j.ejmech.2015.08.046

de Veer, Simon J., Wang, Conan, Harris, Jonathan M., Craik, David J. and Swedberg, Joakim E. (2015). Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library. Journal of Medicinal Chemistry, 58 (20), 8257-8268. doi: 10.1021/acs.jmedchem.5b01148

Yu, Rilei, Seymour, Victoria A. L., Berecki, Geza, Jia, Xinying, Akcan, Muharrem, Adams, David J., Kaas, Quentin and Craik, David J. (2015). Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports, 5 (Art No.: 13264) 13264, 13264. doi: 10.1038/srep13264

Henriques, Sonia Troeira, Huang, Yen-Hua, Chaousis, Stephanie, Sani, Marc-Antoine, Poth, Aaron G., Separovic, Frances and Craik, David J. (2015). The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells. Chemistry and Biology, 22 (8) 3107, 1087-1097. doi: 10.1016/j.chembiol.2015.07.012

Huang, Yen-Hua, Henriques, Sonia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin and Craik, David J. (2015). Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5 (1) 12974, 1-15. doi: 10.1038/srep12974

Himeno, Kohei, Rosengren, K. Johan, Inoue, Tomoko, Perez, Rodney H., Colgrave, Michelle L., Lee, Han Siean, Chan, Lai Y., Henriques, Sonia Troeira, Fujita, Koji, Ishibashi, Naoki, Zendo, Takeshi, Wilaipun, Pongtep, Nakayama, Jiro, Leelawatcharamas, Vichien, Jikuya, Hiroyuki, Craik, David J. and Sonomoto, Kenji (2015). Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. Biochemistry, 54 (31), 4863-4876. doi: 10.1021/acs.biochem.5b00196

Vriens, Kim, Cools, Tanne L., Harvey, Peta J., Craik, David J., Spincemaille, Pieter, Cassiman, David, Braem, Annabel, Vleugels, Jozef, Nibbering, Peter H., Drijfhout, Jan Wouter, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2015). Synergistic activity of the plant defensin HsAFP1 and caspofungin against Candida albicans biofilms and planktonic cultures. PLoS ONE, 10 (8) e0132701, 1-22. doi: 10.1371/journal.pone.0132701

Luo, Sulan, Zhangsun, Dongting, Harvey, Peta J., Kaas, Quentin, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Li, Xiaodan, Tsetlin, Victor. I., Christensen, Sean, Romero, Haylie K., McIntrye, Melissa, Dowell, Cheryl, Baxter, James, C., Elmslie, Keith S., Craik, David J. and McIntosh, Michael (2015). Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 (30), e4026-e4035. doi: 10.1073/pnas.1503617112

de Veer, Simon J., Swedberg, Joakim E., Akcan, Muharrem, Rosengren, K. Johan, Brattsand, Maria, Craik, David J. and Harris, Jonathan M. (2015). Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition. Biochemical Journal, 469 (2), 243-253. doi: 10.1042/BJ20150412

Holliday, Gemma L., Bairoch, Amos, Bagos, Pantelis G., Chatonnet, Arnaud, Craik, David J., Flinn, Robert D., Henrissat, Bernard, Landsman, David, Manning, Gerard, Nagano, Nozomi, O'Donovan, Claire, Pruitt, Kim D., Rawlings, Neil D., Saier, Milton, Sowdhamini, Ramanathan, Spedding, Michael, Srinivasan, Narayanaswamy, Vriend, Gert, Babbitt, Patricia C. and Bateman, Alex (2015). Key challenges for the creation and maintenance of specialist protein resources. Proteins: Structure, Function and Bioinformatics, 83 (6), 1005-1013. doi: 10.1002/prot.24803

Kaas, Quentin and Craik, David J. (2015). Bioinformatics-aided venomics. Toxins, 7 (6), 2159-2187. doi: 10.3390/toxins7062159

Bernath-Levin, Kalia, Nelson, Clark, Elliott, Alysha G., Jayasena, Achala S., Millar, A. Harvey, Craik, David J. and Mylne, Joshua S. (2015). Peptide macrocyclization by a bifunctional endoprotease. Chemistry and Biology, 22 (5), 571-582. doi: 10.1016/j.chembiol.2015.04.010

Wang, Conan K., Northfield, Susan Ellen, Swedberg, Joakim E., Colless, Barbara, Chaousis, Stephanie, Price, David A., Liras, Spiros and Craik, David J. (2015). Exploring experimental and computational markers of cyclic peptides: charting islands of permeability. European Journal of Medicinal Chemistry, 97, 202-213. doi: 10.1016/j.ejmech.2015.04.049

Malik, U., Silva, O. N., Fensterseifer, I. C. M., Chan, A., Clark, R. J., Franco, O. L., Daly, N. L. and Craik, D. J. (2015). In vivo efficacy of anuran rypsin inhibitory peptides against Staphylococcal Skin infection and the impact of peptide cyclization. Antimicrobial Agents and Chemotherapy, 59 (4), 2113-2121. doi: 10.1128/AAC.04324-14

Zhang, Jun, Li, Jintian, Huang, Zebo, Yang, Bing, Zhang, Xiaojie, Li, Dehua, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2015). Transcriptomic screening for cyclotides and other cysteine-rich proteins in the metallophyte Viola baoshanensis. Journal of Plant Physiology, 178, 17-26. doi: 10.1016/j.jplph.2015.01.017

Zhangsun, Dongting, Zhu, Xiaopeng, Wu, Yong, Hu, Yuanyan, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Luo, Sulan (2015). Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding. The Journal of Biological Chemistry, 290 (15), 9855-9862. doi: 10.1074/jbc.M114.632646

Haugaard-Kedstrom, Linda, Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Rinderknecht, Ernst, Wade, John D., Craik, David J. and Rosengren, Karl Johan (2015). Solution structure, aggregation behavior, and flexibility of human relaxin-2. ACS Chemical Biology, 10 (3), 891-900. doi: 10.1021/cb500918v

Huang, Yen-Hua, Chaousis, Steph, Cheneval, Olivier, Craik, David J. and Henriques, Sonia Troeira (2015). Optimization of the cyclotide framework to improve cell penetration properties. Frontiers in Pharmacology, 6 (17) 17, 1-7. doi: 10.3389/fphar.2015.00017

Babbitt, Patricia C, Bagos, Pantelis G, Bairoch, Amos, Bateman, Alex, Chatonnet, Arnaud, Chen, Mark Jinan, Craik, David J, Finn, Robert D, Gloriam, David, Haft, Daniel H, Henrissat, Bernard, Holliday, Gemma L, Isberg, Vignir, Kaas, Quentin, Landsman, David, Lenfant, Nicolas, Manning, Gerard, Nagano, Nozomi, Srinivasan, Narayanaswamy, O'Donovan, Claire, Pruitt, Kim D, Sowdhamini, Ramanathan, Rawlings, Neil D, Saier Jr., Milton H, Sharman, Joanna L, Spedding, Michael, Tsirigos, Konstantinos D, Vastermark, Ake and Vriend, Gerrit (2015). Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database The Journal of Biological Databases and Curation, 2015 (bav063) doi: 10.1093/database/bav063

Fensterseifer, Isabel C. M., Silva, Osmar N., Malik, Uru, Ravipati, Anjaneya S., Novaes, Natasha R. F., Miranda, Paolo R. R., Rodrigues, Elaine A., Moreno, Susana E., Craik, David J. and Franco, Octavio L. (2015). Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus. Peptides, 63 (3), 38-42. doi: 10.1016/j.peptides.2014.10.019

Durek, Thomas and Craik, David J. (2015). Therapeutic conotoxins: a US patent literature survey. Expert Opinion in Therapeutic Patents, 25 (10), 1159-1173. doi: 10.1517/13543776.2015.1054095

Zhang, Jun, Hua, Zhengshuang, Huang, Zebo, Chen, QiZhu, Long, Qingyun, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2014). Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases. Planta, 241 (4), 929-940. doi: 10.1007/s00425-014-2229-5

Wang, Conan K., Northfield, Susan E., Colless, Barbara, Chaousis, Stephanie, Hamernig, Ingrid, Lohman, Rink-Jan, Nielsen, Daniel S., Schroeder, Christina I., Liras, Spiros, Price, David, A., Fairlie, David and Craik, David J. (2014). Rational design and synthesis of orally bioavailable peptides guided by NMR amide temperature coefficients. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 111 (49), 17504-17509. doi: 10.1073/pnas.1417611111

Conibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c

Mahatmanto, Tunjung, Mylne, Joshua S., Poth, Aaron G., Swedberg, Joakim E., Kaas, Quentin, Schaefer, Hanno and Craik, David J. (2014). The evolution of Momordica cyclic peptides. Molecular Biology and Evolution, 32 (2), 392-405. doi: 10.1093/molbev/msu307

Vink, Simone, Daly, Norelle L., Steen, Natalie, Craik, David J. and Alewood, Paul F. (2014). Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90 (1), 308-317. doi: 10.1016/j.toxicon.2014.08.068

Nielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Hill, Timothy A., Lucke, Andrew J., Craik, David J., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Improving on nature: making a cyclic heptapeptide orally bioavailable. Angewandte Chemie - International Edition, 53 (45), 12059-12063. doi: 10.1002/anie.201405364

Taylor, Carol M., Northfield, Susan E., Wang, Conan K. and Craik, David J. (2014). Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1. Tetrahedron, 70 (42), 7669-7674. doi: 10.1016/j.tet.2014.06.058

Wang, Conan K., King, Gordon J., Northfield, Susan E., Ojeda, Paola G. and Craik, David J. (2014). Racemic and quasi-racemic x-ray structures of cyclic disulfide-rich peptide drug scaffolds. Angewandte Chemie - International Edition, 53 (42), 11236-11241. doi: 10.1002/anie.201406563

Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823

Ojeda, Paola G., Chan, Lai Y., Poth, Aaron G., Wang, Conan K. and Craik, David J. (2014). The role of disulfide bonds in structure and activity of chlorotoxin. Future Medicinal Chemistry, 6 (15), 1617-1628. doi: 10.4155/FMC.14.93

Conibear, Anne C. and Craik, David J. (2014). The chemistry and biology of theta defensins. Angewandte Chemie International Edition, 53 (40), 10612-10623. doi: 10.1002/anie.201402167

Spincemaille, Pieter, Alborzinia, Hamed, Dekervel, Jeroen, Windmolders, Petra, van Pelt, Jos, Cassiman, David, Cheneval, Olivier, Craik, David J., Schur, Julia, Ott, Ingo, Wolfl, Stefan, Cammue, Bruno P. A and Thevissen, Karin (2014). The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells. Molecules, 19 (9), 15088-15102. doi: 10.3390/molecules190915088

Wang, Conan K., Northfield, Susan E., Swedberg, Joakim E., Harvey, Peta J., Mathiowetz, Alan M., Price, David A, Liras, Spiros and Craik, David J. (2014). Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR. Journal of Physical Chemistry B, 118 (38), 11129-11136. doi: 10.1021/jp506678f

Henriques, Sonia Troeira, Huang, Yen-Hua, Chaousis, Steph, Wang, Conan and Craik, David J. (2014). Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting. Chembiochem, 15 (13), 1956-1965. doi: 10.1002/cbic.201402144

Delattin, Nicolas, De Brucker, Katrijn, Craik, David J., Cheneval, Olivier, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2014). Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation. Antimicrobial Agents and Chemotherapy, 58 (8), 4974-4977. doi: 10.1128/AAC.03336-14

Conibear, Anne C. and Craik, David J. (2014). Chemie und Biologie von Theta-Defensinen. Angewandte Chemie, 126 (40), 10786-10798. doi: 10.1002/ange.201402167

Berecki, G., Daly, N. L., Huang, Y. H., Vink, S., Craik, D. J., Alewood, P. F. and Adams, D. J. (2014). Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels. British Journal of Pharmacology, 171 (13), 3313-3327. doi: 10.1111/bph.12686

D'Souza, Charlotte, Troeira Henriques, Sonia, Wang, Conan K. and Craik, David J. (2014). Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1. European Journal of Medicinal Chemistry, 88, 10-18. doi: 10.1016/j.ejmech.2014.06.047

Cheneval, Olivier, Schroeder, Christina I., Durek, Thomas, Walsh, Phillip, Huang, Yen-Hua, Liras, Spiros, Price, David A. and Craik, David J. (2014). Fmoc-based synthesis of disulfide-rich cyclic peptides. Journal of Organic Chemistry, 79 (12), 5538-5544. doi: 10.1021/jo500699m

Paulsen, B. S., Craik, D. J., Dunstan, D. E., Stone, B. A. and Bacic, A. (2014). The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein. Carbohydrate Polymers, 106 (1), 460-468. doi: 10.1016/j.carbpol.2014.01.009

Mahatmanto, Tunjung, Poth, Aaron, Mylne, Joshua S. and Craik, David J. (2014). A comparative study of extraction methods reveals preferred solvents for cystine knot peptide isolation from Momordica cochinchinensis seeds. Fitoterapia, 95, 22-33. doi: 10.1016/j.fitote.2014.02.016

Akondi, Kalyana, Muttenthaler, Markus, Dutertre, Sébastien, Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2014). Discovery, synthesis, and structure: activity relationships of conotoxins. Chemical Reviews, Articles ASAP (11), 1-33. doi: 10.1021/cr400401e

Northfield, Susan E., Wang, Conan K., Schroeder, Christina I., Durek, Thomas, Kan, Meng-Wei, Swedberg, Joakim E. and Craik, David J. (2014). Disulﬁde-rich macrocyclic peptides as templates in drug design. European Journal of Medicinal Chemistry, 77 (2), 248-257. doi: 10.1016/j.ejmech.2014.03.011

Elliott, Alysha G., Delay, Christina, Liu, Huanle, Phua, Zaiyang, Rosengren, K. Johan, Benfield, Aurelie H., Panero, Jose L., Colgrave, Michelle L., Jayasena, Achala S., Dunse, Kerry M., Anderson, Marilyn A., Schilling, Edward E., Ortiz-Barrientos, Daniel, Craik, David J. and Mylne, Joshua S. (2014). Evolutionary origins of a bioactive peptide buried within preproalbumin. The Plant Cell, 26 (3), 981-995. doi: 10.1105/tpc.114.123620

Delattin, Nicolas, De Brucker, Katrijn, Craik, David J., Cheneval, Olivier, Frohlich, Mirjam, Veber, Matija, Girandon, Lenart, Davis, Tayla, R., Weeks, Anne E., Kumamoto, Carol A., Cos, Paul, Coenye, Tom, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2014). The plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability. Antimicrobial Agents and Chemotherapy, 58 (5), 2647-2656. doi: 10.1128/AAC.01274-13

Schroeder, Christina I., Swedberg, Joakim E., Withka, Jane M., Rosengren, K. Johan, Akcan, Muharrem, Clayton, Daniel J., Daly, Norelle L., Cheneval, Olivier, Borzilleri, Kris A., Griffor, Matt, Stock, Ingrid, Colless, Barbara, Walsh, Phillip, Sunderland, Phillip, Reyes, Allan, Dullea, Robert, Ammirati, Mark, Liu, Shenping, McClure, Kim F., Tu, Meihua, Bhattacharya, Samit K., Liras, Spiros, Price, David A. and Craik, David J. (2014). Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry and Biology, 21 (2), 284-294. doi: 10.1016/j.chembiol.2013.11.014

Lay, Fung T., Poon, Simon, McKenna, James A., Connelly, Angela A., Barbeta, Barbara L., McGinness, Bruce S., Fox, Jennifer L., Daly, Norelle L., Craik, David J., Heath, Robyn L. and Anderson, Marilyn A. (2014). The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions. BMC Plant Biology, 14 (1) 41, 41.1-41.13. doi: 10.1186/1471-2229-14-41

Conibear, Anne C., Bochen, Alexander, Rosengren, K. Johan, Stupar, Petar, Wang, Conan, Kessler, Horst and Craik, David J. (2014). The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif. ChemBioChem, 15 (3), 451-459. doi: 10.1002/cbic.201300568

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558

Jia, Xinying, Kwon, Soohyun, Wang, Ching-I Anderson, Huang, Yen-Hua, Chan, Lai Y., Tan, Chia Chia, Rosengren, K. Johan, Mulvenna, Jason P., Schroeder, Christina I. and Craik, David J. (2014). Semienzymatic cyclization of disulfide-rich peptides using sortase A. Journal of Biological Chemistry, Papers in Press (10), 1-25. doi: 10.1074/jbc.M113.539262

Luo, Sulan, Zhangsun, Dongting, Schroeder, Christina I., Zhu, Xiaopeng, Hu, Yuanyan, Wu, Yong, Weltzin, Maegan M., Eberhard, Spencer, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Whiteaker, Paul (2014). A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors. FASEB Journal, Early Edition (4), 1-12. doi: 10.1096/fj.13-244103

Craik, D. P. L. Aude, Linke, N. M., Harty, T. P., Ballance, C. J., Lucas, D. M., Steane, A. M. and Allcock, D. T. C. (2014). Microwave control electrodes for scalable, parallel, single-qubit operations in a surface-electrode ion trap. Applied Physics B: Lasers and Optics, 114 (1-2), 3-10. doi: 10.1007/s00340-013-5716-7

Moon, H., Lee, C. S., Inder, K. L., Sharma, S., Choi, E., Black, D. M., Lê Cao, K.-A., Winterford, C., Coward, J. I., Ling, M. T., Craik, D. J., Parton, R. G., Russell, P.J., Hill, M. M. and The Australian Prostate Cancer BioResource (2014). PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer. Oncogene, 33 (27), 3561-3570. doi: 10.1038/onc.2013.315

Kedarisetti, Pradyumna, Mizianty, Marcin J., Kaas, Quentin, Craik, David J. and Kurgan, Lukasz (2014). Prediction and characterization of cyclic proteins from sequences in three domains of life. Biochimica et Biophysica Acta: Proteins and Proteomics, 1844 (1), 181-190. doi: 10.1016/j.bbapap.2013.05.002

Wang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s

Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The Self-Association of the Cyclotide Kalata B2 in Solution is Guided by Hydrophobic Interactions (vol 100, pg 453, 2013). Biopolymers, 102 (1), 136-136. doi: 10.1002/bip.22443

Daly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240

Akcan, Muharrem, Stroud, Mark R., Hansen, Stacey J., Clark, Richard J., Daly, Norelle L., Craik, David J. and Olson, James M. (2013). Erratum: Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy (Journal of Medicinal Chemistry (2011) 54 (782-787) DOI: 10.1021/jm101018r). Journal of Medicinal Chemistry, 56 (23), 9807-9807. doi: 10.1021/jm4016119

Arnison, Paul G., Bibb, Mervyn J., Bierbaum, Gabriele, Bowers, Albert A., Bugni, Tim S., Bulaj, Grzegorz, Camarero, Julio A., Campopiano, Dominic J., Challis, Gregory L., Clardy, Jon, Cotter, Paul D., Craik, David J., Dawson, Michael, Dittmann, Elke, Donadio, Stefano, Dorrestein, Pieter C., Entian, Karl-Dieter, Fischbach, Michael A., Garavelli, John S., Göransson, Ulf, Gruber, Christian W., Ha, Daniel H., Hemscheidt, Thomas K., Hertweck, Christian, Hill, Colin, Horswill, Alexander R., Jaspars, Marcel, Kelly, Wendy L., Klinman, Judith P. ... Van Der Donk, Wilfred A. (2013). Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F). Natural Product Reports, 30 (12), 1568-1569. doi: 10.1039/c3np90040a

De Coninck, Barbara, Carron, Delphine, Tavormina, Patrizia, Willem, Lander, Craik, David J., Vos, Christine, Thevissen, Karin, Mathys, Janick and Cammue, Bruno P. A. (2013). Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance. Journal of Experimental Biology, 64 (17), 5297-5307. doi: 10.1093/jxb/ert295

Grishin, Anton A., Cuny, Hartmut, Hung, Andrew, Clark, Richard J., Brust, Andreas, Akondi, Kalyana, Alewood, Paul F., Craik, David J. and Adams, David J. (2013). Identifying key amino acid residues that affect alpha-conotoxin AuIB inhibition of alpha3beta4 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 288 (48), 34428-34442. doi: 10.1074/jbc.M113.512582

Koehbach, Johannes, O'Brien, Margaret, Muttenthaler, Markus, Miazzo, Marion, Akcan, Muharrem, Elliott, Alysha G., Daly, Norelle L., Harvey, Peta J., Arrowsmith, Sarah, Gunasekera, Sunithi, Smith, Terry J., Wray, Susan, Göransson, Ulf, Dawson, Philip E., Craik, David J., Freissmuth, Michael and Gruber, Christian W. (2013). Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences of the United States of America, 110 (52), 21183-21188. doi: 10.1073/pnas.1311183110

Henriques, Sónia Troeira, Thorstholm, Louise, Huang, Yen-Hua, Getz, Jennifer A., Daugherty, Patrick S. and Craik, David J. (2013). A novel quantitative kinase assay using bacterial surface display and flow cytometry. PloS One, 8 (11) e80474, e80474.1-e80474.7. doi: 10.1371/journal.pone.0080474

Luo, Sulan, Zhangsun, Dongting, Zhu, Xiaopeng, Wu, Yong, Hu, Yuanyan, Christensen, Sean, Harvey, Peta J., Akcan, Muharrem, Craik, David J. and McIntosh, Michael (2013). Characterization of a novel alpha-conotoxin TxID from Conus textile that potently blocks rat alpha3/beta4 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry, Article ASAP (13), A-I. doi: 10.1021/jm401254c

Craik, David J. and Malik, Uru (2013). Cyclotide biosynthesis (vol 17, pg 546, 2013). Current Opinion in Chemical Biology, 17 (5), 868-868. doi: 10.1016/j.cbpa.2013.09.010

He, Wen-Jun, Chan, Lai Yue, Clark, Richard J., Tang, Jun, Zeng, Guang-Zhi, Franco, Octavio L., Cantacessi, Cinzia, Craik, David J., Daly, Norelle L. and Tan, Ning-Hua (2013). Novel inhibitor cystine knot peptides from momordica charantia. PLoS ONE, 8 (10) e75334, e75334.1-e75334.10. doi: 10.1371/journal.pone.0075334

Torcato, Ines M., Huang, Yen-Hua, Franquelim, Henri G., Gaspar, Diana D., Craik, David J., Castanho, Miguel A. R. B. and Henriques, Sonia Troeira (2013). The Antimicrobial Activity of Sub3 is Dependent on Membrane Binding and Cell-Penetrating Ability. Chembiochem, 14 (15), 2013-2022. doi: 10.1002/cbic.201300274

Craik, David J. (2013). Foreword for ICCP2012 issue of Biopolymers Peptide Science Circular Proteins: never ending possibilities. Biopolymers: Peptide Science, 100 (5), iii-v. doi: 10.1002/bip.22366

Malagon, David, Botterill, Bonnie, Gray, Darren J., Lovas, Erica, Duke, Mary, Gray, Christian, Kopp, Steven R., Knott, Lyn M., McManus, Donald P., Daly, Norelle L., Mulvenna, Jason, Craik, David J. and Malcolm K Jones (2013). Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites. Biopolymers, 100 (5), 461-470. doi: 10.1002/bip.22229

Clark, Richard J., Preza, Gloria C., Tan, Chia Chia, van Dijk, Johannes W. A., Fung, Eileen, Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2013). Design, synthesis and characterisation of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers: Peptide Science, 100 (5), 519-526. doi: 10.1002/bip.22350

Gerlach, Samantha L., Göransson, Ulf, Kaas, Quentin, Craik, David J. and Gruber, Christian W. (2013). A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic and peptidomic analysis. Biopolymers: Peptide Science, 100 (5), 433-437. doi: 10.1002/bip.22258

Inserra, Marco C., Kompella, Shiva N., Vetter, Irina, Brust, Andreas, Daly, Norelle L., Cuny, Hartmut, Craik, David J., Alewood, Paul F., Adams, David J. and Lewis, Richard J. (2013). Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology, 86 (6), 791-799. doi: 10.1016/j.bcp.2013.07.016

Poth, Aaron, Chan, Lai Y. and Craik, David J. (2013). Cyclotides as grafting frameworks for protein engineering and drug design applications. Biopolymers: Peptide Science, 100 (5), 480-491. doi: 10.1002/bip.22284

Craik, David J. and Malik, Uru (2013). Cyclotide biosynthesis. Current Opinion In Chemical Biology, 17 (4), 546-554. doi: 10.1016/j.cbpa.2013.05.033

Garvey, Megan, Meehan, Sarah, Gras, Sally L., Schirra, Horst, Craik, David J., Van der Weerden, Nicole L., Anderson, Marilyn A., Gerrard, Juliet A. and Carver, John A. (2013). A radish seed antifungal peptide with a high amyloid fibril-forming propensity. Biochimica et Biophysica Acta: Proteins and Proteomics, 1834 (8), 1615-1623. doi: 10.1016/j.bbapap.2013.04.030

Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions. Peptide Science, Accepted Article (5), 1-16. doi: 10.1002/bip.22269

Craik, David J. (2013). Joseph Rudinger memorial lecture: discovery and applications of cyclotides. Journal of Peptide Science, 19 (7), 393-407. doi: 10.1002/psc.2523

Gruendemann, Carsten, Thell, Kathrin, Lengen, Karin, Garcia-Kaeufer, Manuel, Huang, Yen-Hua, Huber, Roman, Craik, David J., Schabbauer, Gernot and Gruber, Christian W. (2013). Cyclotides suppress human T-Lymphocyte proliferation by an interleukin 2-dependent mechanism. Plos One, 8 (6) e68016, e68016.1-e68016.12. doi: 10.1371/journal.pone.0068016

Getz, Jennifer A., Cheneval, Olivier, Craik, David J. and Daugherty, Patrick S. (2013). Design of a cyclotide antagonist of neuropilin-1 and-2 that potently inhibits endothelial cell migration. ACS Chemical Biology, 8 (6), 1147-1154. doi: 10.1021/cb4000585

Yu, Rilei, Kompella, Shiva N., Adams, David J., Craik, David J. and Kaas, Quentin (2013). Determination of the alpha-conotoxin Vc1.1 binding site on the alpha 9 alpha 10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry, 56 (9), 3557-3567. doi: 10.1021/jm400041h

Kaas, Quentin and Craik, David J. (2013). NMR of plant proteins. Progress in Nuclear Magnetic Resonance Spectroscopy, 71, 1-34. doi: 10.1016/j.pnmrs.2013.01.003

Cowper, Ben, Craik, David J. and Macmillan, Derek (2013). Making ends meet: chemically mediated circularization of recombinant proteins. ChemBioChem, 14 (7), 809-812. doi: 10.1002/cbic.201300105

Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A. and Daly, Norelle L. (2013). High-affinity cyclic peptide matriptase inhibitors. Journal of Biological Chemistry, 288 (19), 13885-13896. doi: 10.1074/jbc.M113.460030

Conibear, Anne C., Rosengren, K. Johan, Daly, Norelle L., Henriques, Sonia Troeira and Craik, David J. (2013). The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15), 10830-10840. doi: 10.1074/jbc.M113.451047

Torcato, Inês M., Huang, Yen-Hua, Franquelim, Henri G., Gaspar, Diana, Craik, David J., Castanho, Miguel A. R. B. and Henriques, Sonia Troeira (2013). Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria. Biochimica et Biophysica Acta, 1828 (3), 944-955. doi: 10.1016/j.bbamem.2012.12.002

Chan, Lai Yue, Zhang, Veronica M., Huang, Yen-hua, Waters, Norman C., Bansal, Paramjit S., Craik, David J. and Daly, Norelle L. (2013). Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity. Chembiochem, 14 (5), 617-624. doi: 10.1002/cbic.201300034

Akcan, Muharrem, Cao, Ying, Chongzu, Fan and Craik, David J. (2013). The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold. Bioorganic and Medicinal Chemistry, 21 (12), 3590-3596. doi: 10.1016/j.bmc.2013.02.012

Luo, Sulan, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, McIntyre, Melissa, Christensen, Sean, Akcan, Muharrem, Craik, David J. and McIntosh, J. Michael (2013). Characterization of a novel α-conotoxin from Conus textile that selectively targets alpha 6/alpha 3 beta 2 beta 3 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 288 (2), 894-902. doi: 10.1074/jbc.M112.427898

Chan, Lai Yue, He, Wenjun, Tan, Ninghua, Zeng, Guangzhi, Craik, David J. and Daly, Norelle L. (2013). A new family of cystine knot peptides from the seeds of Momordica cochinchinensis. Peptides, 39 (1), 29-35. doi: 10.1016/j.peptides.2012.09.018

Gao, Bin, Harvey, Peta J., Craik, David J., Ronjat, Michel, De Waard, Michel and Zhu, Shunyi (2013). Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold. Bioscience Reports, 33 (3) e00047, e00047.1-e00047.15. doi: 10.1042/BSR20130052

Schroeder, Christina I., Swedberg, Joakim E. and Craik, David J. (2013). Recent progress towards pharmaceutical applications of disulfide-rich cyclic peptides. Current Protein and Peptide Science, 14 (6), 532-552. doi: 10.2174/13892037113149990069

Craik, David J. and Schroeder, Christina I. (2013). Peptides from Mamba venom as pain killers. Angewandte Chemie-International Edition, 52 (11), 3071-3073. doi: 10.1002/anie.201209851

Craik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055

Conibear, Anne C., Rosengren, K. Johan, Harvey, Peta J. and Craik, David J. (2012). Structural characterization of the cyclic cystine ladder motif of θ-defensins. Biochemistry, 51 (48), 9718-9726. doi: 10.1021/bi301363a

Wang, Conan K., Wacklin, Hanna P. and Craik, David J. (2012). Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions. Journal of Biological Chemistry, 287 (52), 43884-43898. doi: 10.1074/jbc.M112.421198

Eliasen, Rasmus, Daly, Norelle L., Wulff, Birgitte S., Andresen, Thomas L., Conde-Frieboes, Kilian W. and Craik, David J. (2012). Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1. Journal of Biological Chemistry, 287 (48), 40493-40501. doi: 10.1074/jbc.M112.395442

Hall, Kristopher, Lee, Tzong-Hsien, Daly, Norelle L., Craik, David J. and Aguilar, Marie-Isabel (2012). Gly6 of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes. BBA: Biomembranes, 1818 (9), 2354-2361. doi: 10.1016/j.bbamem.2012.04.007

Henriques, Sonia Troeira, Huang, Yen-Hua, Castanho, Miguel A. R. B., Bagatolli, Luis A., Sonza, Secondo, Tachedjan, Gilda, Daly, Norelle L. and Craik, David J. (2012). Phosphatidylethanolamine-binding is a conserved feature of cyclotide-membrane interactions. Journal of Biological Chemistry, 287 (40), 33629-33643. doi: 10.1074/jbc.M112.372011

Conlan, Brendon F., Colgrave, Michelle L., Gillon, Amanda D., Guarino, Rosemary, Craik, David J. and Anderson, Marilyn A. (2012). Insights into processing and cyclization events associated with biosynthesis of the cyclic peptide kalata B1. Journal of Biological Chemistry, 287 (33), 28037-28046. doi: 10.1074/jbc.M112.347823

Daly, Norelle, David Wilson and Craik, David (2012). Cyclic peptides from plants and their promise in drug design. Australian Biochemist, 43 (2), 7-9.

Craik, David J. (2012). Protein folding: Turbo-charged crosslinking. Nature Chemistry, 4 (8), 600-602. doi: 10.1038/nchem.1417

Cemazar, M., Kwon, S., Mahatmanto, T., Ravipati, A. S. and Craik, David J. (2012). Discovery and applications of disulfide-rich cyclic peptides. Current Topics in Medicinal Chemistry, 12 (14), 1534-1545. doi: 10.2174/156802612802652484

Conibear, Anne, Daly, Norelle L. and Craik, David J. (2012). Quantification of small cyclic disulfide-rich peptides. Biopolymers, 98 (6), 518-524. doi: 10.1002/bip.22121

Mylne, Joshua S., Chan, Lai Yue, Chanson, Aurelie H., Daly, Norelle L., Schaefer, Hanno, Bailey, Timothy L., Nguyencong, Philip, Cascales, Laura and Craik, David J. (2012). Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis. Plant Cell, 24 (7), 2765-2778. doi: 10.1105/tpc.112.099085

Poth, Aaron G., Mylne, Joshua S., Grassl, Julia, Lyons, Russell E., Millar, A. Harvey, Colgrave, Michelle L. and Craik, David J. (2012). Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). Journal of Biological Chemistry, 287 (32), 27033-27046. doi: 10.1074/jbc.M112.370841

Craik, David J. and Allewell, Norma M. (2012). Thematic minireview series on circular proteins. Journal of Biological Chemistry, 287 (32), 26999-27000. doi: 10.1074/jbc.R112.390344

Schroeder, Christina I. and Craik, David J. (2012). Therapeutic potential of conopeptides. Future Medicinal Chemistry, 4 (10), 1243-1255. doi: 10.4155/FMC.12.70

Thorstholm, L. and Craik, D. J. (2012). Discovery and applications of naturally occurring cyclic peptides. Drug Discovery Today: Technologies, 9 (1), e13-e21. doi: 10.1016/j.ddtec.2011.07.005

Yu, Rilei, Kaas, Quentin and Craik, David J. (2012). Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor. The Journal of Physical Chemistry B, 116 (21), 6097-6105. doi: 10.1021/jp301352d

Zhu, Shunyi, Gao, Bin, Harvey, Peta J. and Craik, David J. (2012). Dermatophytic defensin with antiinfective potential. Proceedings of the National Academy of Sciences of the United States of America, 109 (22), 8495-8500. doi: 10.1073/pnas.1201263109

Henriques, Sonia Troeira and Craik, David J. (2012). Importance of the cell membrane on the mechanism of action of cyclotides. ACS Chemical Biology, 7 (4), 626-636. doi: 10.1021/cb200395f

Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012). Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4), 446-455. doi: 10.1016/j.toxicon.2010.12.003

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012). Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 (8) doi: 10.2174/138161212799315858

Craik, David J., Swedberg, Joakim E., Mylne, Joshua S. and Cemazar, Masa (2012). Cyclotides as a basis for drug design. Expert Opinion On Drug Discovery, 7 (3), 179-194. doi: 10.1517/17460441.2012.661554

Craik, David J. (2012). Host-defense activities of cyclotides. Toxins, 4 (2), 139-156. doi: 10.3390/toxins4020139

Franco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams. David J. and Mari, Frank (2012). RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs. Biochemical Pharmacology, 83 (3), 419-426. doi: 10.1016/j.bcp.2011.11.006

Pinto, Michelle F. S., Fensterseifer, Isabel C. M., Migliolo, Ludovico, Sousa, Daniel A., de Capdville, Guy, Arboleda, Jorge W., Colgrave, Michelle, Craik, David J., Magalhaes, Beatriz S., Dias, Simoni C. and Franco, Octavio L. (2012). Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane. The Journal of Biological Chemistry, 287 (1), 134-147. doi: 10.1074/jbc.M111.294009

Clark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3

Schroeder, Christina I., Nielsen, Katherine J., Adams, Denise A., Loughnan, Marion L., Thomas, Linda, Alewood, Paul F., Lewis, Richard J. and Craik, David J. (2012). Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers, 98 (4), 345-356. doi: 10.1002/bip.22031

Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3

Kaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012). ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 (D1), D325-D330. doi: 10.1093/nar/gkr886

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401

Sando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel and Craik, David J. (2011). A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16), 2456-2462. doi: 10.1002/cbic.201100450

Smith, Amanda B., Daly, Norelle L. and Craik, David J. (2011). Cyclotides: A patent review. Expert Opinion On Therapeutic Patents, 21 (11), 1657-1672. doi: 10.1517/13543776.2011.620606

Conibear, Anne C. and

Professor David Craik

Publications

Book Chapters

Journal Articles