In vivo axonal transport in ALS mice

Dr Andrew Tosolini is postdoctoral Research Associate under the guidance of Professor Giampietro Schiavo in the Department of Neuromuscular Diseases at Queen Square Institute of Neurology, UCL, London. His projects focuses on the cell biology of motor neurons in health and disease. Andrew has been working on determining the mechanisms governing axonal transport in vulnerable and resistant motor neurons in motor neuron disease/amyotrophic lateral sclerosis. In addition, his project also explores spinal cord circuitry to understand the mechanisms of transcytosis and neuron-to-neuron communication.

He completed a Bachelor of Medical Science with Honours in Neuroscience (2010) and a PhD in Anatomy (2015) at the University of New South Wales (UNSW), Sydney. His PhD project was under Dr Renee Morris in a spinal cord injury lab and focused on characterising the spatial organisation between skeletal muscles and their innervating motor neurons. This served as a vital tool to use the muscle as a conduit to deliver therapeutic genes to the innervating spinal motor neurons. Andrew was awarded the Dean’s Merit List for his outstanding contribution to research as a postgraduate student from the Faculty of Medicine.