Journal Articles
Rivera, Isela Sarahi, French, Juliet D., Bitar, Mainá, Sivakumaran, Haran, Nair, Sneha, Kaufmann, Susanne, Hillman, Kristine M., Moradi Marjaneh, Mahdi, Beesley, Jonathan and Edwards, Stacey L. (2024). GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers. PLOS Genetics, 20 (11) ARTN e1011490, e1011490. doi: 10.1371/journal.pgen.1011490
Wang, Lu, Bitar, Mainá, Lu, Xue, Jacquelin, Sebastien, Nair, Sneha, Sivakumaran, Haran, Hillman, Kristine M., Kaufmann, Susanne, Ziegman, Rebekah, Casciello, Francesco, Gowda, Harsha, Rosenbluh, Joseph, Edwards, Stacey L. and French, Juliet D. (2024). CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair. Molecular Cancer, 23 (1) 101. doi: 10.1186/s12943-024-02021-y
Bitar, Mainá, Rivera, Isela Sarahi, Almeida, Isabela, Shi, Wei, Ferguson, Kaltin, Beesley, Jonathan, Lakhani, Sunil R., Edwards, Stacey L. and French, Juliet D. (2023). Redefining normal breast cell populations using long noncoding RNAs. Nucleic Acids Research, 51 (12), 6389-6410. doi: 10.1093/nar/gkad339
Tuano, Natasha K., Beesley, Jonathan, Manning, Murray, Shi, Wei, Perlaza-Jimenez, Laura, Malaver-Ortega, Luis F., Paynter, Jacob M., Black, Debra, Civitarese, Andrew, McCue, Karen, Hatzipantelis, Aaron, Hillman, Kristine, Kaufmann, Susanne, Sivakumaran, Haran, Polo, Jose M., Reddel, Roger R., Band, Vimla, French, Juliet D., Edwards, Stacey L., Powell, David R., Chenevix-Trench, Georgia and Rosenbluh, Joseph (2023). CRISPR screens identify gene targets at breast cancer risk loci. Genome Biology, 24 (1) 59, 1-23. doi: 10.1186/s13059-023-02898-w
Morphis, Allison C., Edwards, Stacey L., Erdenebat, Purevsuren, Kumar, Lalit and Li, Jian (2022). Auxin-inducible degron system reveals temporal-spatial roles of HSF-1 and its transcriptional program in lifespan assurance. Frontiers in Aging, 3 899744, 1-14. doi: 10.3389/fragi.2022.899744
Amici, David R., Ansel, Daniel J., Metz, Kyle A., Smith, Roger S., Phoumyvong, Claire M., Gayatri, Sitaram, Chamera, Tomasz, Edwards, Stacey L., O'Hara, Brendan P., Srivastava, Shashank, Brockway, Sonia, Takagishi, Seesha R., Cho, Byoung-Kyu, Goo, Young Ah, Kelleher, Neil L., Ben-Sahra, Issam, Foltz, Daniel R., Li, Jian and Mendillo, Marc L. (2022). C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways. Proceedings of the National Academy of Sciences of the United States of America, 119 (27) e2111262119, 1-12. doi: 10.1073/pnas.2111262119
Quinn, Michael CJ, McCue, Karen, Shi, Wei, Johnatty, Sharon E., Beesley, Jonathan, Civitarese, Andrew, O'Mara, Tracy A, Glubb, Dylan M, Tyrer, Jonathan P, Armasu, Sebastian M., Ong, Jue-Sheng, Gharahkhani, Puya, Lu, Yi, Gao, Bo, Patch, Ann-Marie, Fasching, Peter A., Beckmann, Matthias W., Lambrechts, Diether, Vergote, Ignace, Velez Edwards, Digna, Beeghly-Fadiel, Alicia, Benitez, Javier, Garcia, Maria J, Goodman, Marc T., Dork, Thilo, Durst, Matthias, Modugno, Francesmary, Moysich, Kirsten, du Bois, Andreas ... Chenevix-Trench, Georgia (2021). Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Cancer Epidemiology Biomarkers and Prevention, 30 (9), 1669-1680. doi: 10.1158/1055-9965.epi-20-1817
Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann ... Fletcher, Olivia (2021). CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4), 842-854. doi: 10.1038/s41416-020-01185-w
French, J. D. and Edwards, S. L. (2020). The role of noncoding variants in heritable disease. Trends in Genetics, 36 (11), 880-891. doi: 10.1016/j.tig.2020.07.004
Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Shi, Wei, Hillman, Kristine M., Kaufmann, Susanne, Hussein, Nehal, Kar, Siddhartha, Lima, Luize G., Ham, Sunyoung, Möller, Andreas, Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). eQTL Colocalization Analyses Identify NTN4 as a Candidate Breast Cancer Risk Gene. American Journal of Human Genetics, 107 (4), 778-787. doi: 10.1016/j.ajhg.2020.08.006
Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). Non-coding RNAs underlie genetic predisposition to breast cancer. Genome Biology, 21 (1) 7, 7. doi: 10.1186/s13059-019-1876-z
Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lima, Luize G., Hillman, Kristine M., Kaufmann, Susanne, Tuano, Natasha, Hussein, Nehal, Ham, Sunyoung, Mukhopadhyay, Pamela, Kazakoff, Stephen, Lee, Jason S., Michailidou, Kyriaki, Barnes, Daniel R., Antoniou, Antonis C., Fachal, Laura, Dunning, Alison M., Easton, Douglas F., Waddell, Nicola, Rosenbluh, Joseph, Möller, Andreas, Chenevix-Trench, Georgia, French, Juliet D. and Edwards, Stacey L. (2020). Chromatin interactome mapping at 139 independent breast cancer risk signals. Genome Biology, 21 (1) 8, 8. doi: 10.1186/s13059-019-1877-y
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Homologous recombination DNA repair defects in PALB2-associated breast cancers. npj Breast Cancer, 5 (1) 23. doi: 10.1038/s41523-019-0115-9
McCabe, Mark J., Gauthier, Marie-Emilie A., Chan, Chia-Ling, Thompson, Tanya J., De Sousa, Sunita M.C., Puttick, Clare, Grady, John P., Gayevskiy, Velimir, Tao, Jiang, Ying, Kevin, Cipponi, Arcadi, Deng, Niantao, Swarbrick, Alex, Thomas, Melissa L., Lord, Reginald V., Johns, Amber L., Kohonen-Corish, Maija, O’Toole, Sandra A., Clark, Jonathan, Mueller, Simon A., Gupta, Ruta, McCormack, Ann I., Dinger, Marcel E., Cowley, Mark J., Aghmesheh, Morteza, Amor, David, Andrews, Lesley, Antill, Yoland, Armitage, Shane ... Young, Mary-Anne (2019). Development and validation of a targeted gene sequencing panel for application to disparate cancers. Scientific Reports, 9 (1) 17052, 17052. doi: 10.1038/s41598-019-52000-3
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Publisher Correction: Homologous recombination DNA repair defects in PALB2-associated breast cancers (npj Breast Cancer, (2019), 5, 1, (23), 10.1038/s41523-019-0115-9). npj Breast Cancer, 5 (1) 44. doi: 10.1038/s41523-019-0140-8
Figlioli, Gisella, Bogliolo, Massimo, Catucci, Irene, Caleca, Laura, Lasheras, Sandra Viz, Pujol, Roser, Kiiski, Johanna I., Muranen, Taru A., Barnes, Daniel R., Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K., Leslie, Goska, Aalfs, Cora M., Balleine, Rosemary, Baxter, Robert, Braye, Stephen, Carpenter, Jane, Dahlstrom, Jane, Forbes, John, Lee, C. Soon, Marsh, Deborah, Morey, Adrienne, Pathmanathan, Nirmala, Scott, Rodney, Simpson, Peter, Spigelman, Allan, Wilcken, Nicholas, Yip, Desmond ... Peterlongo, Paolo (2019). The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. npj Breast Cancer, 5 (1) 38, 38. doi: 10.1038/s41523-019-0127-5
Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C., kConFab, Sexton, Adrienne, Christian, Alice, Trainer, Alison, Spigelman, Allan, Fellows, Andrew, Shelling, Andrew, De Fazio, Anna, Blackburn, Anneke, Crook, Ashley, Meiser, Bettina, Patterson, Briony, Clarke, Christine, Saunders, Christobel, Hunt, Clare, Scott, Clare, Amor, David, Marsh, Deborah, Edkins, Edward ... Antill, Yoland (2018). Heritable DNA methylation marks associated with susceptibility to breast cancer. Nature Communications, 9 (1) 867. doi: 10.1038/s41467-018-03058-6
Milevskiy, Michael J. G., Sandhu, Gurveen K., Wronski, Anna, Korbie, Darren, Brewster, Brooke L., Shewan, Annette, Edwards, Stacey L., French, Juliet D. and Brown, Melissa A. (2018). MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer. Oncotarget, 9 (71), 33577-33588. doi: 10.18632/oncotarget.26094
Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Cowper-Sal Lari, Richard, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Børge G, Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2018). Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999)). Nature communications, 9 (1) 16193. doi: 10.1038/ncomms16193
Burke, Leslie J., Sevcik, Jan, Gambino, Gaetana, Tudini, Emma, Mucaki, Eliseos J., Shirley, Ben C., Whiley, Phillip, Parsons, Michael T., De Leeneer, Kim, Gutiérrez-Enríquez, Sara, Santamariña, Marta, Caputo, Sandrine M., Santana dos Santos, Elizabeth, Soukupova, Jana, Janatova, Marketa, Zemankova, Petra, Lhotova, Klara, Stolarova, Lenka, Borecka, Mariana, Moles-Fernández, Alejandro, Manoukian, Siranoush, Bonanni, Bernardo, Edwards, Stacey L., Blok, Marinus J., van Overeem Hansen, Thomas, Rossing, Maria, Diez, Orland, Vega, Ana, Claes, Kathleen B.M. ... ENIGMA Consortium (2018). BRCA1 and BRCA2 5′ noncoding region variants identified in breast cancer patients alter promoter activity and protein binding. Human Mutation, 39 (12), 2025-2039. doi: 10.1002/humu.23652
Michailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha, Bolla, Manjeet K, Wang, Qin, Tyrer, Jonathan, Dicks, Ed, Lee, Andrew, Wang, Zhaoming, Allen, Jamie, Keeman, Renske, Eilber, Ursula, French, Juliet D, Qing Chen, Xiao, Fachal, Laura, McCue, Karen, McCart Reed, Amy E, Ghoussaini, Maya, Carroll, Jason S, Jiang, Xia, Finucane, Hilary, Adams, Marcia ... Easton, Douglas F (2017). Association analysis identifies 65 new breast cancer risk loci. Nature, 551 (7678), 92-94. doi: 10.1038/nature24284
Betts, Joshua A., Moradi Marjaneh, Mahdi, Al-Ejeh, Fares, Lim, Yi Chieh, Shi, Wei, Sivakumaran, Haran, Tropee, Romain, Patch, Ann.-Marie, Clark, Michael B., Bartonicek, Nenad, Wiegmans, Adrian P., Hillman, Kristine M., Kaufmann, Susanne, Bain, Amanda L., Gloss, Brian S., Crawford, Joanna, Kazakoff, Stephen, Wani, Shivangi, Wen Shu W., Day, Bryan, Moller, Andreas, Cloonan, Nicole, Pearson,John, Brown, Melissa A., Mercer, Timothy R., Waddell, Nicola, Khanna, Kum Kum, Dray, Eloise, Dinger, Marcel E. ... French, Juliet D. (2017). Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage. American Journal of Human Genetics, 101 (2), 255-266. doi: 10.1016/j.ajhg.2017.07.007
Powell, Joseph E., Fung, Jenny N., Shakhbazov, Konstantin, Sapkota, Yadav, Cloonan, Nicole, Hemani, Gibran, Hillman, Kristine M., Kaufmann, Susanne, Luong, Hien T., Bowdler, Lisa, Painter, Jodie N., Holdsworth-Carson, Sarah J., Visscher, Peter M., Dinger, Marcel E., Healey, Martin, Nyholt, Dale R., French, Juliet D., Edwards, Stacey L., Rogers, Peter A. W. and Montgomery, Grant W. (2016). Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339. Human Molecular Genetics, 25 (22), 5046-5058. doi: 10.1093/hmg/ddw320
Darabi, Hatef, Beesley, Jonathan, Droit, Arnaud, Kar, Siddhartha, Nord, Silje, Marjaneh, Mahdi Moradi, Soucy, Penny, Michailidou, Kyriaki, Ghoussaini, Maya, Wahl, Hanna Fues, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Alonso, M. Rosario, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Benitez, Javier, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Broeks, Annegien, Bruening, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Choi, Ji-Yeob, Conroy, Don M. ... Dunning, Alison M. (2016). Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs). Scientific Reports, 6 ARTN 32512. doi: 10.1038/srep32512
Milevskiy, Michael J. G., Al-Ejeh, Fares, Saunus, Jodi M., Northwood, Korinne S., Bailey, Peter J., Betts, Joshua A., McCart Reed, Amy E., Nephew, Kenneth P., Stone, Andrew, Gee, Julia M. W., Dowhan, Dennis H., Dray, Eloise, Shewan, Annette M., French, Juliet D., Edwards, Stacey L., Clark, Susan J., Lakhani, Sunil R. and Brown, Melissa A. (2016). Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer. Human Molecular Genetics, 25 (15), 3269-3283. doi: 10.1093/hmg/ddw177
Painter, Jodie N., Kaufmann, Susanne, O'Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B. and Edwards, Stacey L. (2016). A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding. American Journal of Human Genetics, 98 (6), 1159-1169. doi: 10.1016/j.ajhg.2016.04.012
Cheng, Timothy H. T., Thompson, Deborah J., O'Mara, Tracy A., Painter, Jodie N., Glubb, Dylan M., Flach, Susanne, Lewis, Annabelle, French, Juliet D., Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W., Nyholt, Dale R., Ahmed, Shahana, Healey, Catherine S., Shah, Mitul, Dennis, Joe, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander ... Spurdle, Amanda B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature Genetics, 48 (6), 667-674. doi: 10.1038/ng.3562
Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001
Wronski, A., Sandhu, G. K., Milevskiy, M. J., Brewster, B. L., Bridge, J. A., Shewan, A. M., Edwards, S. L., French, J. D. and Brown, M. A. (2016). MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland. Oncogenesis, 5 (4) e218, e218.1-e218.9. doi: 10.1038/oncsis.2016.27
Dunning, Alison M., Michailidou, Kyriaki, Kuchenbaecker, Karoline B., Thompson, Deborah, French, Juliet D., Beesley, Jonathan, Healey, Catherine S., Kar, Siddhartha, Pooley, Karen A., Lopez-Knowles, Elena, Dicks, Ed, Barrowdale, Daniel, Sinnott-Armstrong, Nicholas A., Sallari, Richard C., Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Marjaneh, Mahdi Moradi, Lee, Jason S., Hills, Margaret, Jarosz, Monika, Drury, Suzie, Canisius, Sander, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Hopper, John L., Southey, Melissa C., Broeks, Annegien ... Edwards, Stacey L. (2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics, 48 (4), 374-386. doi: 10.1038/ng.3521
French, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047
Vicente, Cristina T., Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Mitchell, Hayley, Bain, Lisa, Glubb, Dylan M., Lee, Jason S., French, Juliet D. and Ferreira, Manuel A. R. (2015). Long-range modulation of PAG1 expression by 8q21 allergy risk variants. American Journal of Human Genetics, 97 (2) 1909, 329-336. doi: 10.1016/j.ajhg.2015.06.010
Edwards, Stacey L., Poongavanam, Vasanthanathan, Kanwar, Jagat R., Roy, Kislay, Hillman, Kristine M., Prasad, Neerati, Leth-Larsen, Rikke, Petersen, Michael, Marusic, Maja, Plavec, Janez, Wengel, Jesper and Veedu, Rakesh N. (2015). Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition. Chemical Communications, 51 (46), 9499-9502. doi: 10.1039/c5cc02756j
Painter J.N., O'Mara T.A., Batra J., Cheng T., Lose F.A., Dennis J., Michailidou K., Tyrer J.P., Ahmed S., Ferguson K., Healey C.S., Kaufmann S., Hillman K.M., Walpole C., Moya L., Pollock P., Jones A., Howarth K., Martin L., Gorman M., Hodgson S., De Polanco M.M.E., Sans M., Carracedo A., Castellvi-Bel S., Rojas-Martinez A., Santos E., Teixeira M.R., Carvajal-Carmona L. ... Spurdle A.B. (2015). Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics, 24 (5), 1478-1492. doi: 10.1093/hmg/ddu552
Glubb, Dylan, Maranian, Mel J., Michailidou, Kyriaki, Pooley, Karen A., Meyer, Kerstin, Kar, Siddhartha, Carlebur, Saskia, O'Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Canisius, Sander, Hopper, John L., Southey, Melissa C., Tsimiklis, Helen, Apicella, Carmel, Schmidt, Marjanka K., Broeks, Annegien, Hogervorst, Frans B., van der Schoot, C. Ellen, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter, Ruebner, Matthias, Ekici, Arif B., Beckmann, Matthias W. ... French, Juliet D. (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics, 96 (1), 5-20. doi: 10.1016/j.ajhg.2014.11.009
Darabi, Hatef, Mccue, Karen, Beesley, Jonathan, Michailidou, Kyriaki, Nord, Silje, Kar, Siddhartha, Humphreys, Keith, Thompson, Deborah, Ghoussaini, Maya, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Canisius, Sander, Scott, Christopher G., Apicella, Carmel, Hopper, John L., Southey, Melissa C., Stone, Jennifer, Broeks, Annegien, Schmidt, Marjanka K., Scott, Rodney J., Lophatananon, Artitaya, Muir, Kenneth, Beckmann, Matthias W., Ekici, Arif B., Fasching, Peter A., Heusinger, Katharina, dos-Santos-Silva, Isabel, Peto, Julian ... Chenevix-Trench, Georgia (2015). Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. American Journal of Human Genetics, 97 (1), 22-34. doi: 10.1016/j.ajhg.2015.05.002
Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Lari, Richard Cowper-Sal, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Borge G., Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5 (1) 4999, 4999.1-4999.12. doi: 10.1038/ncomms5999
Meyer, Kerstin B., O'Reilly, Martin, Michailidou, Kyriaki, Carlebur, Saskia, Edwards, Stacey L., French, Juliet D., Prathalingham, Radhika, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, de Santiago, Ines, Hopper, John L., Tsimiklis, Helen, Apicella, Carmel, Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Van 't Veer, Laura J., Hogervorst, Frans B., Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter A., Lux, Michael P., Ekici, Arif B., Beckmann, Matthias W., Peto, Julian, dos Santos Silva, Isabel ... Easton, Douglas F. (2013). Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1. American Journal of Human Genetics, 93 (6), 1046-1060. doi: 10.1016/j.ajhg.2013.10.026
Edwards, Stacey L., Beesley, Jonathan, French, Juliet D. and Dunning, Alison M. (2013). Beyond GWASs: illuminating the dark road from association to function. American Journal of Human Genetics, 93 (5), 779-797. doi: 10.1016/j.ajhg.2013.10.012
Mercer, Tim R., Edwards, Stacey L., Clark, Michael B., Neph, Shane J., Wang, Hao, Stergachis, Andrew B., John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S., Ruan, Yijun, Nielsen, Lars K., Mattick, John S. and Stamatoyannopoulos, John A. (2013). DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements. Nature Genetics, 45 (8), 852-859. doi: 10.1038/ng.2677
Bojesen, Stig E., Pooley, Karen A., Johnatty, Sharon E., Beesley, Jonathan, Michailidou, Kyriaki, Tyrer, Jonathan P., Edwards, Stacey L., Pickett, Hilda A., Shen, Howard C., Smart, Chanel E., Hillman, Kristine M., Mai, Phuong L., Lawrenson, Kate, Stutz, Michael D., Lu, Yi, Karevan, Rod, Woods, Nicholas, Johnston, Rebecca L., French, Juliet D., Chen, Xiaoqing, Weischer, Maren, Nielsen, Sune F., Maranian, Melanie J., Ghoussaini, Maya, Ahmed, Shahana, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Dennis, Joe ... Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) (2013). Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics, 45 (4), 371-384. doi: 10.1038/ng.2566
French, Juliet D., Ghoussaini, Maya, Edwards, Stacey L., Meyer, Kerstin B., Michailidou, Kyriaki, Ahmed, Shahana, Khan, Sofia, Maranian, Mel J., O'Reilly, Martin, Hillman, Kristine M., Betts, Joshua A., Carro, Thomas, Bailey, Peter J., Dicks, Ed, Beesley, Jonathan, Tyrer, Jonathan, Maia, Ana-Teresa, Beck, Andrew, Knoblauch, Nicholas W., Chen, Constance, Kraft, Peter, Barnes, Daniel, Gonzalez-Neira, Anna, Rosario Alonso, M., Herrero, Daniel, Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Luccarini, Craig ... Dunning, Alison M. (2013). Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. American Journal of Human Genetics, 92 (4), 489-503. doi: 10.1016/j.ajhg.2013.01.002
Wheeler, Megan, Chardon, Antoine, Goubet, Astrid, Morihiro, Kunihiko, Tsan, Sze Yee, Edwards, Stacey L., Kodama, Tetsuya, Obika, Satoshi and Veedu, Rakesh N. (2012). Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases. Chemical Communications, 48 (89), 11020-11022. doi: 10.1039/C2CC36464F
Betts, Joshua A., French, Juliet D., Brown, Melissa A. and Edwards, Stacey L. (2012). Long-range transcriptional regulation of breast cancer genes. Genes, Chromosomes and Cancer, 52 (2), 113-125. doi: 10.1002/gcc.22020
Brewster, Brooke L., Rossiello, Francesca, French, Juliet D., Edwards, Stacey L., Wong, Ming, Wronski, Ania, Whiley, Phillip, Waddell, Nic, Chen, Xiaowei, Bove, Betsy, kConFab, Hopper, John L., John, Esther M., Andrulis, Irene, Daly, Mary, Volorio, Sara, Bernard, Loris, Peissel, Bernard, Manoukian, Siranoush, Barile, Monica, Pizzamiglio, Sara, Verderio, Paolo, Spurdle, Amanda B., Radice, Paolo, Godwin, Andrew K., Southey, Melissa C., Brown, Melissa A. and Peterlongo, Paolo (2012). Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site. Human Mutation, 33 (12), 1665-1675. doi: 10.1002/humu.22159
Lauridsen, Lasse H., Shamaileh, Hadi A., Edwards, Stacey L., Taran, Elena and Veedu, Rakesh N. (2012). Rapid one-step selection method for generating nucleic acid aptamers: Development of a DNA aptamer against α-bungarotoxin. PLoS One, 7 (7) e41702, e41702.1-e41702.6. doi: 10.1371/journal.pone.0041702
Crouzier, Lucile, Dubois, Camille, Edwards, Stacey L., Lauridsen, Lasse H., Wengel, Jesper and Veedu, Rakesh N. (2012). Efficient reverse transcription using locked Nucleic Acid Nucleotides towards the evolution of Nuclease resistant RNA Aptamers. PLoS One, 7 (4), e35990-1-e35990-5. doi: 10.1371/journal.pone.0035990
Peters, Kate M., Edwards, Stacey L., Nair, Shalima S., French, Juliet D., Bailey, Peter J., Salkield, Kathryn, Stein, Sandra, Wagner, Sarah, Francis, Glenn D., Clark, Susan J. and Brown, Melissa A. (2012). Androgen receptor expression predicts breast cancer survival: The role of genetic and epigenetic events. BMC Cancer, 12 (132) 132, 1-10. doi: 10.1186/1471-2407-12-132
Dubois, Camille, Campbell, Meghan A., Edwards, Stacey L., Wengel, Jesper and Veedu, Rakesh N. (2012). Stepping towards highly flexible aptamers: Enzymatic recognition studies of unlocked nucleic acid nucleotides. Chemical Communications, 44 (44), 5503-5505. doi: 10.1039/c2cc31316b
Smart, C.E., Wronski, A., French, J.D., Edwards, S.L., Asselin-Labat, M.L., Waddell, N., Peters, K., Brewster, B.L., Brooks, K., Simpson, K., Manning, N., Lakhani, S.R., Grimmond, S., Lindeman, G.J., Visvader, J.E. and Brown, M.A. (2011). Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. Oncogene, 30 (13), 1597-1607. doi: 10.1038/onc.2010.538
Pettigrew, C. A., French, J. D., Saunus, J. M., Edwards, S. L., Sauer, A. V., Smart, C. E., Lundstrom, H. T., Wiesner, C., Spurdle, A. B., Rothnagel, J. A. and Brown, M. A. (2010). Identification and functional analysis of novel BRCA1 transcripts, including mouse Brca1-Iris and human pseudo-BRCA1. Breast Cancer Research and Treatment, 119 (1), 239-247. doi: 10.1007/s10549-008-0256-2
Saunus, J., French, J.D., Edwards, S.L., Beveridge, D.J., Hatchell, E.C., Wagner, S.A., Stein, S.R., Davidson, A., Simpson, K.J., Francis, G.D., Leedman, P.J. and Brown, M.A. (2008). Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR. Cancer Research, 68 (22), 9469-9478. doi: 10.1158/0008-5472.CAN-08-1159
Edwards, Stacey L., Brough, Rachel, Lord, Christopher J., Natrajan, Rachael, Vatcheva, Radost, Levine, Douglas A., Boyd, Jeff, Reis, Jorge S. and Ashworth, Alan (2008). Resistance to therapy caused by intragenic deletion in BRCA2. Nature, 451 (7182), 1111-1115. doi: 10.1038/nature06548
Saunus, Jodi M., Edwards, Stacey L., French, Juliet D., Smart, Chanel E. and Brown, Melissa A. (2007). Regulation of BRCA1 messenger RNA stability in human epithelial cell lines and during cell cycle progression. FEBS Letters, 581 (18), 3435-3442. doi: 10.1016/j.febslet.2007.06.046
Wardrop, Stacey L., Brown, Melissa A. and kConFab Investigators (2005). Identification of two evolutionarily conserved and functional regulatory elements in intron 2 of the human BRCA1 gene. Genomics, 86 (3), 316-328. doi: 10.1016/j.ygeno.2005.05.006
Wardrop, S. L., Wells, C., Ravasi, T., Hume, D. A. and Richardson, D. R. (2002). Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism. Journal of Leukocyte Biology, 71 (1), 99-106. doi: 10.1189/jlb.71.1.99
Wardrop, S. L., Watts, R. N. and Richardson, D. R. (2000). Nitrogen monoxide activates iron regulatory protein 1 RNA - binding activity by two possible mechanisms: effect on the [4Fe-4S] cluster and iron mobilization from cells. Biochemistry, 39 (10), 2748-2758. doi: 10.1021/bi991099t
Wardrop, S. L. and Richardson, D. R. (2000). Interferon-γ and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages. European Journal of Biochemistry, 267 (22), 6586-6593. doi: 10.1046/j.1432-1327.2000.01752.x
Wardrop, S., Fowler, A., O'Callaghan, ., Giffard, P. and Timms, P. (1999). Characterization of the koala biovar of Chlamydia pneumoniae at four gene loci - ompAVD4 ompB, 16S rRNA, groESL spacer region. Systematic and Applied Microbiology, 22 (1), 22-27. doi: 10.1016/S0723-2020(99)80024-1
Wardrop, S. L. and Richardson, D. R. (1999). The effect of intracellular iron concentration and nitrogen monoxide on NRAMP2 expression and non-transferrin-bound iron uptake. European Journal of Biochemistry, 263 (1), 41-49. doi: 10.1046/j.1432-1327.1999.00447.x
Conference Papers
Shang, Hanqing, Ansari, Sarah, Dhar, Shweta, Irranejadparizi, Mahdieh, Edwards, Stacey, Honkomp, Jessica, Siehr, Meagan, Aiena, Bethany, Nikityn, Mary, Bearden, Diana, Menefee, Deleene and Bushan, Sita (2024). A Multidisciplinary Telehealth Approach to Breast Cancer Prevention in a Veteran Population. San Antonio Breast Cancer Symposium, San Antonio Tx, Dec 05-09, 2023. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.SABCS23-PO3-27-09
French, J. D., Johnatty, S. E., Lu, Y., Beesley, J., Gao, B., Henderson, M. J., Russell, A. J., Hillman, K. M., Kaufmann, S., Sivakumaran, H., Lee, J. S., Meyer, K. B., Chenevix-Trench, G., DeFazio, A., Macgregor, S. and Edwards, S. L. (2015). Genome-wide association study identifies PSIP1 associated with progression-free survival in epithelial ovarian cancer. HOBOKEN: WILEY-BLACKWELL.
Brown, M. A., French, J. D., Edwards, S. L., Peters, K. M., Wronski, A., Smart, C. E., Brewster, B. L., Wee, J. E., Waddell, N. and Francis, G. D. (2010). Identification of novel biomarkers for breast cancer, including brca1-associated breast cancer. IMPAKT Breast Cancer Conference 2010, Brussels, Belgium, MAY 06-08, 2010. Oxford, England, U.K.: Oxford University Press. doi: 10.1093/annonc/mdq145
French, J. D., Tan-Wong, S. M., Edwards, S., Smart, C. E., Proudfoot, N. J. and Brown, M. A. (2008). Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene. Fifth European Gordon Research Conference on Mammary Gland Biology, Lucca (Barga), Italy, 1-6 June 2008.
French, J. D., Edwards, S. L., Saunus, J. M., Tan-Wong, S. M., Brewster, B., Hardie, K. M., Leedman, P. J., Proudfoot, N. J. and Brown, M. A. (2008). Identification of functional regulatory elements in the non-coding regions of the BRCA1 gene. kConFab Familial Breast Cancer conference 2008, Couran Cove, Queensland, 2008.
Brewster, B., Brown, M. A., Edwards, S. L., French, J. D., Leedman, P., Proudfoot, N. J., Saunus, J. M., Southey, M., Tavtigian, S and Wong, S. M. (2007). Identification of novel mutation targets in the breast cancer susceptibility gene BRCA1 and genes that encode regulators of BRCA1. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.
Saunus, Jodi M., Wardrop, Stacey L., French, Juliet D., Beveridge, Dianne J., Hatchell, Esme C., Dinnis, Diane M., Gason, Alexandra A., Simpson, Kaylene J., Leedman, Peter J. and Brown, Melissa A. (2006). Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R. ComBio 2006, Brisbane, Queensland, Australia, 24-28 September, 2006.
Saunus, Jodi M., French, Juliet D., Edwards, Stacey L., Beveridge, Dianne J., Hatchell, Esme C., Wagner, Sarah A., Gason, Alexandra A., Simpson, Kaylene J., Leedman, Peter J. and Brown, Melissa A. (2006). Identification of RNA-binding proteins that regulate BRCA1 expression. Familial Cancer 2006: Research and Practice. A combined meeting of kConFab, Australian Ovarian Cancer Study (AOCS) and the Family Cancer Clinics of Australia and New Zealand, Couran Cove, South Stradbroke Island, Queensland, Australia, 16-19 August 2006. Kathleen Cuningham Foundation Consortium (kConFab).
Saunus, J. M., Wardrop, S. L., French, J. D., Beveridge, D. J., Hatchell, E. C., Gason, A. A., Simpson, K.J., Leedman, P. J. and Brown, M. A. (2005). Hur post-transcriptionally regulates BRCA1: involvement of elements in the BRCA1 3' untranslated region. Molecular Approaches to Controlling Cancer, New York, 3-5 June, 2005.
Wardrop, S. L., Saunus, J. M., French, J. D., Leedman, P. J. and Brown, M. A. (2005). Transcriptional and post-transcriptional regulation of the breast cancer susceptibility gene 1 (BRCA1). National Cancer Research Institute Conference, Birmingham, UK, 2-5 Oct, 2005.
French, J. D., Saunus, J. M., Wardrop, S. L. and Brown, M. A. (2005). Regulation of BRCA1 by Heregulin. Familial Cancer 2005: Research and Practice, Couran Cove, 30 Aug - 3 Sept, 2005.
Wardrop, S. L., Lane, T. and Brown, M. A. (2002). Identification of critical regulatory elements in the breast cancer susceptibility (BRCA1) gene. ComBio 2002, Sydney, Australia, 29 September - 3 October, 2002. Kent Town, South Australia:
Saunus, J. M., Wardrop, S. L. and Brown, M. A. (2002). Identification of cis and trans regulators in the BRCA1 3'untranslated region. ComBio 2002, Sydney, Australia, 29 September - 3 October, 2002. Kent Town, South Australia:
Wardrop, S. and Richardson, D. R. (1999). Lipopolysaccaride and/or interferon-g regulate the expression of Nramp2, Nramp1 and the tranferrin receptor independently of the iron-regulatory protein in macrophages: A possible role of Nramp2 in host defence?. Proceedings of the International Conference on Oxidative Pathways in Health and Disease, Veterinary Fac. Conference Cen., Univ. of Sydney, 1 - 4 Dec,1999. Sydney: Univ. of Sydney.
Wardrop, S., Watts, R. N. and Richardson, D. R. (1999). The mechanisms involved in nitrogen monoxide (NO) mediated iron-regulatory protein 1 (IRP1) activation and cellular iron mobilization. ComBio99, Conrad Jupiter's, Gold Coast, Qld., 27 - 30 Sept,1999. Kent Town, SA: Sally Jay Conferences.
Wardrop, S. and Richardson, D. R. (1999). Interferon-g and lipopolysaccharide differentially regulate the expression of the iron transporter Nramp2 in macrophages. BomBio99, Conrad Jupiter's, Gold Coast, Qld., 27 - 30 Sept, 1999. Kent Town, SA: Sally Jay Conferences.
Wardrop, S. and Richardson, D. R. (1999). The iron transporter Nramp2 is not regulated like the tranferrin receptor in LMTK-fibroblasts: The roles of non-iron responsive element (IRE) and the IRE-containing Nramp2 mRNA transcripts. ComBio99, Conrad Jupiter's, Gold Coast, Qld., 27 - 30 Sept, 1999. Kent Town, SA: Sally Jay Conferences.
Wardrop, S., Watts, R. N. and Richardson, D. R. (1999). Nitrogen monoxide (NO) activates IRP1-RNA binding by two possible mechanisms - a direct effect on the FES cluster and iron release from cells. Bioiron'99, Sorrento Palace, Sorrento - Naples, Italy, 23 - 28 May 1999. Italy: SGC.
Thesis
Wardrop, Stacey Leanne (2002). Regulation of molecules involved in cellular iron homeostasis and transport. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/105887