Associate Professor Frederic Gachon

Tronstad, Oystein, Zangerl, Barbara, Patterson, Sue, Flaws, Dylan, Yerkovich, Stephanie, Szollosi, Irene, White, Nicole, Garcia-Hansen, Veronica, Leonard, Francisca Rodriguez, Weger, Benjamin D., Gachon, Frédéric, Brain, David, Lavana, Jayshree, Hodgson, Carol and Fraser, John F. (2024). The effect of an improved ICU physical environment on outcomes and post-ICU recovery—a protocol. Trials, 25 (1) 376. doi: 10.1186/s13063-024-08222-6

Ding, Lu, Weger, Benjamin D., Liu, Jieying, Zhou, Liyuan, Lim, Yenkai, Wang, Dongmei, Xie, Ziyan, Liu, Jing, Ren, Jing, Zheng, Jia, Zhang, Qian, Yu, Miao, Weger, Meltem, Morrison, Mark, Xiao, Xinhua and Gachon, Frédéric (2024). Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspring. iScience, 27 (7) 110343, 110343. doi: 10.1016/j.isci.2024.110343

Gachon, Frédéric (2024). Steve Brown's legacy: tools to study the individual human molecular circadian clock and its regulation. European Journal of Neuroscience, 60 (2), 3823-3827. doi: 10.1111/ejn.16335

Gachon, Fred (2023). A gene-by-sex interaction contributes to liver disease susceptibility in women. Nature Medicine, 29 (10), 2422-2423.

Weger, Meltem, Weger, Benjamin D. and Gachon, Frédéric (2023). Understanding circadian dynamics: current progress and future directions for chronobiology in drug discovery. Expert Opinion on Drug Discovery, 18 (8), 893-901. doi: 10.1080/17460441.2023.2224554

Delbès, Anne-Sophie, Quiñones, Mar, Gobet, Cédric, Castel, Julien, Denis, Raphaël G. P., Berthelet, Jérémy, Weger, Benjamin D., Challet, Etienne, Charpagne, Aline, Metairon, Sylviane, Piccand, Julie, Kraus, Marine, Rohde, Bettina H., Bial, John, Wilson, Elizabeth M., Vedin, Lise-Lotte, Minniti, Mirko E., Pedrelli, Matteo, Parini, Paolo, Gachon, Frédéric and Luquet, Serge (2023). Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior. Science Advances, 9 (20) eadf2982, 1-14. doi: 10.1126/sciadv.adf2982

Bignon, Yohan, Wigger, Leonore, Ansermet, Camille, Weger, Benjamin D., Lagarrigue, Sylviane, Centeno, Gabriel, Durussel, Fanny, Götz, Lou, Ibberson, Mark, Pradervand, Sylvain, Quadroni, Manfredo, Weger, Meltem, Amati, Francesca, Gachon, Frédéric and Firsov, Dmitri (2023). Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock. Journal of Clinical Investigation, 133 (8) e167133, 1-17. doi: 10.1172/JCI167133

Miguel-Aliaga, Irene, Vunjak-Novakovic, Gordana, Stephenson, Erin J., Gachon, Frederic, Milagre, Inês, Mills, Evanna, Rubin, Joshua B. and Kelava, Iva (2022). Voicing the need to consider sex-specific differences in research. Developmental Cell, 57 (24), 2675-2678. doi: 10.1016/j.devcel.2022.11.018

Wang, Alison S., Steers, Nicholas J., Parab, Adwaita R., Gachon, Frédéric, Sweet, Matthew J. and Mysorekar, Indira U. (2022). Timing is everything: impact of development, ageing and circadian rhythm on macrophage functions in urinary tract infections. Mucosal Immunology, 15 (6), 1-13. doi: 10.1038/s41385-022-00558-z

Jouffe, Céline, Weger, Benjamin D., Martin, Eva, Atger, Florian, Weger, Meltem, Gobet, Cédric, Ramnath, Divya, Charpagne, Aline, Morin-Rivron, Delphine, Powell, Elizabeth E., Sweet, Matthew J., Masoodi, Mojgan, Uhlenhaut, N. Henriette and Gachon, Frédéric (2022). Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. Proceedings of the National Academy of Sciences, 119 (10) e2200083119, e2200083119. doi: 10.1073/pnas.2200083119

Weger, Meltem, Weger, Benjamin D. and Gachon, Frédéric (2022). The mechanisms and physiological consequences of diurnal hepatic cell size fluctuations: a brief review. Cellular Physiology and Biochemistry, 56 (S2), 1-11. doi: 10.33594/000000489

Ansermet, Camille, Centeno, Gabriel, Bignon, Yohan, Ortiz, Daniel, Pradervand, Sylvain, Garcia, Andy, Menin, Laure, Gachon, Frédéric, Yoshihara, Hikari AI. and Firsov, Dmitri (2021). Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes. Kidney International, 101 (3), 563-573. doi: 10.1016/j.kint.2021.11.016

Weger, Benjamin D. and Gachon, Frédéric (2021). The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiation. Acta Physiologica, 231 (3) e13576, e13576. doi: 10.1111/apha.13576

Weger, Benjamin D., Gobet, Cédric, David, Fabrice P. A., Atger, Florian, Martin, Eva, Phillips, Nicholas E., Charpagne, Aline, Weger, Meltem, Naef, Felix and Gachon, Frédéric (2021). Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms. Proceedings of the National Academy of Sciences, 118 (3) e2015803118, 1-12. doi: 10.1073/pnas.2015803118

Pulido, Robert S., Munji, Roeben N., Chan, Tamara C., Quirk, Clare R., Weiner, Geoffrey A., Weger, Benjamin D., Rossi, Meghan J., Elmsaouri, Sara, Malfavon, Mario, Deng, Aaron, Profaci, Caterina P., Blanchette, Marie, Qian, Tongcheng, Foreman, Koji L., Shusta, Eric V., Gorman, Michael R., Gachon, Frédéric, Leutgeb, Stefan and Daneman, Richard (2020). Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genes. Neuron, 108 (5), 937-952.e7. doi: 10.1016/j.neuron.2020.09.002

Cederroth, Christopher, Gachon, Frédéric and Canlon, Barbara (2020). Time to listen: circadian impact on auditory research. Current Opinion in Physiology, 18, 95-99. doi: 10.1016/j.cophys.2020.09.005

Weger, Meltem, Weger, Benjamin D, Schink, Andrea, Takamiya, Masanari, Stegmaier, Johannes, Gobet, Cédric, Parisi, Alice, Kobitski, Andrei Yu, Mertes, Jonas, Krone, Nils, Strähle, Uwe, Nienhaus, Gerd Ulrich, Mikut, Ralf, Gachon, Frédéric, Gut, Philipp and Dickmeis, Thomas (2020). MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. eLife, 9 e57068, 1-35. doi: 10.7554/elife.57068

Mauvoisin, Daniel and Gachon, Frédéric (2020). Proteomics in circadian biology. Journal of Molecular Biology, 432 (12), 3565-3577. doi: 10.1016/j.jmb.2019.12.004

Gobet, Cédric, Weger, Benjamin Dieter, Marquis, Julien, Martin, Eva, Neelagandan, Nagammal, Gachon, Frédéric and Naef, Felix (2020). Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver. Proceedings of the National Academy of Sciences, 117 (17), 9630-9641. doi: 10.1073/pnas.1918145117

Weger, Benjamin D., Rawashdeh, Oliver and Gachon, Frédéric (2019). At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual development. BioEssays, 41 (9) 1900059, e1900059. doi: 10.1002/bies.201900059

Cederroth, Christopher R., Albrecht, Urs, Bass, Joseph, Brown, Steven A., Dyhrfjeld-Johnsen, J., Gachon, Frederic, Green, Carla B., Hastings, Michael H., Helfrich-Förster, Charlotte, Hogenesch, John B., Lévi, Francis, Loudon, Andrew, Lundkvist, Gabriella B., Meijer, Johanna H., Rosbash, Michael, Takahashi, Joseph S., Young, Michael and Canlon, Barbara (2019). Medicine in the Fourth Dimension. Cell Metabolism, 30 (2), 238-250. doi: 10.1016/j.cmet.2019.06.019

Cederroth, Christopher R., Park, Jung-sub, Basinou, Vasiliki, Weger, Benjamin D., Tserga, Evangelia, Sarlus, Heela, Magnusson, Anna K., Kadri, Nadir, Gachon, Frédéric and Canlon, Barbara (2019). Circadian regulation of cochlear sensitivity to noise by circulating glucocorticoids. Current Biology, 29 (15), 2477-2487.e6. doi: 10.1016/j.cub.2019.06.057

Weger, Benjamin D and Gachon, Frédéric (2019). Microbiota and the clock: sexual dimorphism matters!. Aging, 11 (12), 3893-3894. doi: 10.18632/aging.102051

Gachon, Frédéric (2019). Protéomique circadienne. Biologie aujourd'hui, 212 (3-4), 55-59. doi: 10.1051/jbio/2018025

Weger, Benjamin D, Gobet, Cédric, Yeung, Jake, Martin, Eva, Jimenez, Sonia, Betrisey, Bertrand, Foata, Francis, Berger, Bernard, Balvay, Aurélie, Foussier, Anne, Charpagne, Aline, Boizet-Bonhoure, Brigitte, Chou, Chieh Jason, Naef, Felix and Gachon, Frédéric (2019). The mouse microbiome is required for sex-specific diurnal rhythms of gene expression and metabolism. Cell Metabolism, 29 (2), 362-382. doi: 10.1016/j.cmet.2018.09.023

Almoosawi, Suzana, Vingeliene, Snieguole, Gachon, Frederic, Voortman, Trudy, Palla, Luigi, Johnston, Jonathan D, Van Dam, Rob Martinus, Darimont, Christian and Karagounis, Leonidas G (2018). Chronotype: implications for epidemiologic studies on chrono-nutrition and cardiometabolic health. Advances in Nutrition , 10 (1), 30-42. doi: 10.1093/advances/nmy070

Gachon, Frederic, Yeung, Jake and Naef, Felix (2018). Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock. Genes & Development, 32 (21-22), 1359-1360. doi: 10.1101/gad.320911.118

Mermet, Jérôme, Yeung, Jake, Hurni, Clémence, Mauvoisin, Daniel, Gustafson, Kyle, Jouffe, Céline, Nicolas, Damien, Emmenegger, Yann, Gobet, Cédric, Franken, Paul, Gachon, Frédéric and Naef, Félix (2018). Clock-dependent chromatin topology modulates circadian transcription and behavior. Genes & Development, 32 (5-6), 347-358. doi: 10.1101/gad.312397.118

Yeung, Jake, Mermet, Jérôme, Jouffe, Céline, Marquis, Julien, Charpagne, Aline, Gachon, Frédéric and Naef, Felix (2017). Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs. Genome Research, 28 (2), 182-191. doi: 10.1101/gr.222430.117

Sinturel, Flore and Gachon, Frederic (2017). Diurnal liver mass is associated with ribosome biogenesis. Oncotarget, 8 (57), 96476-96477. doi: 10.18632/oncotarget.22255

Loizides-Mangold, Ursula, Perrin, Laurent, Vandereycken, Bart, Betts, James A., Walhin, Jean-Philippe, Templeman, Iain, Chanon, Stéphanie, Weger, Benjamin D., Durand, Christine, Robert, Maud, Paz Montoya, Jonathan, Moniatte, Marc, Karagounis, Leonidas G., Johnston, Jonathan D., Gachon, Frédéric, Lefai, Etienne, Riezman, Howard and Dibner, Charna (2017). Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro. Proceedings of the National Academy of Sciences, 114 (41), E8565-E8574. doi: 10.1073/pnas.1705821114

Hughes, Michael E., Abruzzi, Katherine C., Allada, Ravi, Anafi, Ron, Arpat, Alaaddin Bulak, Asher, Gad, Baldi, Pierre, de Bekker, Charissa, Bell-Pedersen, Deborah, Blau, Justin, Brown, Steve, Ceriani, M. Fernanda, Chen, Zheng, Chiu, Joanna C., Cox, Juergen, Crowell, Alexander M., DeBruyne, Jason P., Dijk, Derk-Jan, DiTacchio, Luciano, Doyle, Francis J., Duffield, Giles E., Dunlap, Jay C., Eckel-Mahan, Kristin, Esser, Karyn A., FitzGerald, Garret A., Forger, Daniel B., Francey, Lauren J., Fu, Ying-Hui, Gachon, Frédéric ... Hogenesch, John B. (2017). Guidelines for genome-scale analysis of biological rhythms. Journal of Biological Rhythms, 32 (5), 380-393. doi: 10.1177/0748730417728663

Gaspar, Ludmila, Howald, Cedric, Popadin, Konstantin, Maier, Bert, Mauvoisin, Daniel, Moriggi, Ermanno, Gutierrez-Arcelus, Maria, Falconnet, Emilie, Borel, Christelle, Kunz, Dieter, Kramer, Achim, Gachon, Frederic, Dermitzakis, Emmanouil T., Antonarakis, Stylianos E. and Brown, Steven A. (2017). The genomic landscape of human cellular circadian variation points to a novel role for the signalosome. Elife, 6 e24994. doi: 10.7554/eLife.24994

Mauvoisin, Daniel, Atger, Florian, Dayon, Loic, Galindo, Antonio Nunez, Wang, Jingkui, Martin, Eva, Da Silva, Laetitia, Montoliu, Ivan, Collino, Sebastiano, Martin, Francois-Pierre, Ratajczak, Joanna, Canto, Carles, Kussmann, Martin, Naef, Felix and Gachon, Frederic (2017). Circadian and feeding rhythms orchestrate the diurnal liver acetylome. Cell Reports, 20 (7), 1729-1743. doi: 10.1016/j.celrep.2017.07.065

Mauvoisin, Daniel and Gachon, Frederic (2017). Mise en évidence de la physiologie rythmique du foie par protéomique nucléaire. Medecine Sciences, 33 (6-7), 573-576. doi: 10.1051/medsci/20173306005

Sinturel, Flore, Gerber, Alan, Mauvoisin, Daniel, Wang, Jingkui, Gatfield, David, Stubblefield, Jeremy J., Green, Carla B., Gachon, Frederic and Schibler, Ueli (2017). Diurnal oscillations in liver mass and cell size accompany ribosome assembly cycles. Cell, 169 (4), 651-663. doi: 10.1016/j.cell.2017.04.015

Gachon, Frederic, Loizides-Mangold, Ursula, Petrenko, Volodymyr and Dibner, Charna (2017). Glucose homeostasis: regulation by peripheral circadian clocks in rodents and humans. Endocrinology, 158 (5), 1074-1084. doi: 10.1210/en.2017-00218

Sobel, Jonathan Aryeh, Krier, Irina, Andersin, Teemu, Raghav, Sunil, Canella, Donatella, Gilardi, Federica, Kalantzi, Alexandra Styliani, Rey, Guillaume, Weger, Benjamin, Gachon, Frederic, Dal Peraro, Matteo, Hernandez, Nouria, Schibler, Ueli, Deplancke, Bart and Naef, Felix (2017). Transcriptional regulatory logic of the diurnal cycle in the mouse liver. Plos Biology, 15 (4) e2001069, e2001069. doi: 10.1371/journal.pbio.2001069

Atger, Florian, Mauvoisin, Daniel, Weger, Benjamin, Gobet, Cedric and Gachon, Frederic (2017). Regulation of mammalian physiology by interconnected circadian and feeding rhythms. Frontiers in Endocrinology, 8 (MAR) 42. doi: 10.3389/fendo.2017.00042

Petrenko, Volodymyr, Saini, Camille, Giovannoni, Laurianne, Gobet, Cedric, Sage, Daniel, Unser, Michael, Masson, Mounia Heddad, Gu, Guoqiang, Bosco, Domenico, Gachon, Frederic, Philippe, Jacques and Dibner, Charna (2017). Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression. Genes and Development, 31 (4), 383-398. doi: 10.1101/gad.290379.116

Wang, Jingkui, Mauvoisin, Daniel, Martin, Eva, Atger, Florian, Galindo, Antonio Nunez, Dayon, Loic, Sizzano, Federico, Palini, Alessio, Kussmann, Martin, Waridel, Patrice, Quadroni, Manfredo, Dulic, Vjekoslav, Naef, Felix and Gachon, Frederic (2017). Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver. Cell Metabolism, 25 (1), 102-117. doi: 10.1016/j.cmet.2016.10.003

Weger, Benjamin D., Weger, Meltem, Goerling, Benjamin, Schink, Andrea, Gobet, Cedric, Keime, Celine, Poschet, Gernot, Jost, Bernard, Krone, Nils, Hell, Ruediger, Gachon, Frederic, Luy, Burkhard and Dickmeis, Thomas (2016). Extensive regulation of diurnal transcription and metabolism by glucocorticoids. PLoS Genetics, 12 (12) e1006512, e1006512. doi: 10.1371/journal.pgen.1006512

Jouffe, Celine, Gobet, Cedric, Martin, Eva, Metairon, Sylviane, Morin-Rivron, Delphine, Masoodi, Mojgan and Gachon, Frederic (2016). Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism. Scientific Reports, 6 (1) 24631. doi: 10.1038/srep24631

Pouly, Daniel, Chenaux, Sebastien, Martin, Virginie, Babis, Maja, Koch, Rafael, Nagoshi, Emi, Katanaev, Vladimir L., Gachon, Frederic and Staub, Olivier (2016). USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level. Plos One, 11 (1) e0145155, e0145155. doi: 10.1371/journal.pone.0145155

Atger, Florian, Gobet, Cedric, Marquis, Julien, Martin, Eva, Wang, Jingkui, Weger, Benjamin, Lefebvre, Gregory, Descombes, Patrick, Naef, Felix and Gachon, Frederic (2015). Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 112 (47), E6579-E6588. doi: 10.1073/pnas.1515308112

Dibner, Charna and Gachon, Frederic (2015). Circadian dysfunction and obesity: is leptin the missing link?. Cell Metabolism, 22 (3), 359-360. doi: 10.1016/j.cmet.2015.08.008

Mauvoisin, Daniel, Dayon, Loic, Gachon, Frederic and Kussmann, Martin (2015). Proteomics and circadian rhythms: it's all about signaling!. Proteomics, 15 (2-3), 310-317. doi: 10.1002/pmic.201400187

Tokonami, Natsuko, Mordasini, David, Pradervand, Sylvain, Centeno, Gabriel, Jouffe, Celine, Maillard, Marc, Bonny, Olivier, Gachon, Frederic, Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S. and Firsov, Dmitri (2014). Local renal circadian clocks control fluid-electrolyte homeostasis and BP. Journal of the American Society of Nephrology, 25 (7), 1430-1439. doi: 10.1681/ASN.2013060641

Mauvoisin, Daniel, Wang, Jingkui, Jouffe, Celine, Martin, Eva, Atger, Florian, Waridel, Patrice, Quadroni, Manfredo, Gachon, Frederic and Naef, Felix (2014). Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 111 (1), 167-172. doi: 10.1073/pnas.1314066111

Dallmann, Robert, Brown, Steven A. and Gachon, Frederic (2014). Chronopharmacology: new insights and therapeutic implications. Annual Review of Pharmacology and Toxicology, 54 (1), 339-361. doi: 10.1146/annurev-pharmtox-011613-135923

Jouffe, Celine, Cretenet, Gaspard, Symul, Laura, Martin, Eva, Atger, Florian, Naef, Felix and Gachon, Frederic (2013). The circadian clock coordinates ribosome biogenesis. Plos Biology, 11 (1) e1001455, e1001455. doi: 10.1371/journal.pbio.1001455

Gachon, Frederic, Leuenberger, Nicolas, Claudel, Thierry, Gos, Pascal, Jouffe, Celine, Olela, Fabienne Fleury, du Jeu, Xavier de Mollerat, Wahli, Walter and Schibler, Ueli (2011). Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity. Proceedings of the National Academy of Sciences of the United States of America, 108 (12), 4794-4799. doi: 10.1073/pnas.1002862108

Gachon, Frederic and Firsov, Dmitri (2011). The role of circadian timing system on drug metabolism and detoxification. Expert Opinion On Drug Metabolism and Toxicology, 7 (2), 147-158. doi: 10.1517/17425255.2011.544251

Wang, Qing, Maillard, Marc, Schibler, Ueli, Burnier, Michel and Gachon, Frederic (2010). Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 299 (4), R1013-R1019. doi: 10.1152/ajpregu.00241.2010

Gachon, Frederic and Bonnefont, Xavier (2010). Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?. Aging, 2 (2), 101-106. doi: 10.18632/aging.100123

Cretenet, Gaspard, Le Clech, Mikael and Gachon, Frederic (2010). Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liver. Cell Metabolism, 11 (1), 47-57. doi: 10.1016/j.cmet.2009.11.002

Claudel, Thierry, Cretenet, Gaspard, Saumet, Anne and Gachon, Frederic (2007). Crosstalk between xenobiotics metabolism and circadian clock. Febs Letters, 581 (19), 3626-3633. doi: 10.1016/j.febslet.2007.04.009

Gachon, Frederic (2007). Physiological function of PARbZip circadian clock-controlled transcription factors. Annals of Medicine, 39 (8), 562-571. doi: 10.1080/07853890701491034

Benito, Adalberto, Gutierrez, Olga, Pipaon, Carlos, Real, Pedro J., Gachon, Frederic, Ritchie, Alistair E. and Fernandez-Luna, Jose L. (2006). A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. Journal of Biological Chemistry, 281 (50), 38351-38357. doi: 10.1074/jbc.M607004200

Gachon, Frédéric, Olela, Fabienne Fleury, Schaad, Olivier, Descombes, Patrick and Schibler, Ueli (2006). The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metabolism, 4 (1), 25-36. doi: 10.1016/j.cmet.2006.04.015

Gachon, Frédéric, Nagoshi, Emi, Brown, Steven A., Ripperger, Juergen and Schibler, Ueli (2004). The mammalian circadian timing system: from gene expression to physiology. Chromosoma, 113 (3) doi: 10.1007/s00412-004-0296-2

Frédéric Gachon, Philippe Fonjallaz, Francesca Damiola, Pascal Gos, Tohru Kodama, Jozsef Zakany, Denis Duboule, Brice Petit, Mehdi Tafti and Ueli Schibler (2004). The loss of circadian PAR bZip transcription factors results in epilepsy. Genes and Development, 18 (12), 1397-1412. doi: 10.1101/gad.301404

Gaudray, Gilles, Gachon, Frederic, Basbous, Jihane, Biard-Piechaczyk, Martine, Devaux, Christian and Mesnard, Jean-Michael (2002). The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. Journal of Virology, 76 (24), 12813-12822. doi: 10.1128/JVI.76.24.12813-12822.2002

Gachon, F., Devaux, C. and Mesnard, J. M. (2002). Activation of HTLV-1 transcription in the presence of tax is independent of the acetylation of CREB-2 (ATF-4). Virology, 299 (2), 271-278. doi: 10.1006/viro.2002.1501

Gachon, Frédéric, Gaudray, Gilles, Thébault, Sabine, Basbous, Jihane, Koffi, Joseph Aman, Devaux, Christian and Mesnard, Jean-Michel (2001). The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP). FEBS Letters, 502 (1-2), 57-62. doi: 10.1016/S0014-5793(01)02646-1

Gachon, F, Thebault, S, Peleraux, A, Devaux, C and Mesnard, JM (2000). Molecular interactions involved in the transactivation of the human T- cell leukemia virus type 1 promoter mediated by tax and CREB-2 (ATF-4). Molecular and Cellular Biology, 20 (10), 3470-3481. doi: 10.1128/MCB.20.10.3470-3481.2000

Thebault, Sabine, Gachon, Frederic, Lemasson, Isabelle, Devaux, Christian and Mesnard, Jean-Michel (2000). Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression. Journal of Biological Chemistry, 275 (7), 4848-4857. doi: 10.1074/jbc.275.7.4848

Gachon, F., Peleraux, A., Thebault, S., Dick, J., Lemasson, I., Devaux, C. and Mesnard, J. M. (1998). CREB-2, a cellular CRE-Dependent transcription repressor, functions in association with tax as an activator of the human T-cell leukemia virus type 1 promoter. Journal of Virology, 72 (10), 8332-8337.

Fonseka, Sachini, Weger, Benjamin D., Weger, Meltem, Martel, Nick, Hall, Thomas Edward, Varasteh Moradi, Shayli, Gabriel, Christian H., Kramer, Achim, Ferguson, Charles, Fernández-Rojo, Manuel A., Alexandrov, Kirill, Rawashdeh, Oliver, McMahon, Kerrie-Ann, Gachon, Frederic and Parton, Robert G. (2022). A role for caveolar proteins in regulation of the circadian clock.

Associate Professor Frederic Gachon

Publications

Journal Articles

Preprints