Associate Professor Dominic Ng
Associate Professor
School of Biomedical Sciences
+61 7 336 53077
Dr Dominic Ng heads the kinase biology lab.
Researcher biography
Dr Dominic Ng graduated with a BSc (Hons) and gained his PhD from the University of Western Australia. His doctoral studies, conducted in the laboratory of Assoc. Prof. Marie Bogoyevitch, were focused on cardiomyocyte signalling mechanisms regulating pathological tissue growth (ie cardiac hypertrophy). He continued his research training in Singapore as a post-doctoral research fellow based at the Institute of Molecular and Cell Biology, the flagship institute of Singapore's science agency (A*STAR) located at the world renowned Biopolis research precinct. During this time, his research interests turned to the complex regulation of the cytoskeleton and their functions in development and disease.
He returned to the Australian medical research community on an NHMRC Peter Doherty Fellowship (2006-2010) followed by a Faculty Trust Roper Fellowship (2011-2012). In this time, Dominic established an independent research program focused on complex signalling regulation of microtubule organization. In 2013, Dominic was appointed as a Senior Research Fellow, supported by an ARC Future Fellowship (2013-2016) at the Department of Biochemistry within the Bio21 Institute, University of Melbourne. In 2015, Dominic relocated his research group to the School of Biomedical Science, University of Queensland and is currently appointed as an ARC Future Fellow and Senior Lecturer.
Book Chapter
Ng, Dominic Chi Hiung and Byrne, Frances (2012). Stathmin and cancer. Cytoskeleton and Human Disease. (pp. 259-284) edited by Maria Kavallaris. New York, NY USA: Humana Press. doi: 10.1007/978-1-61779-788-0_14
Journal Articles
Yan, Yu, Sankar, Baradwaj Simha, Mirza, Bilal, Ng, Dominic C. M., Pelletier, Alexander R., Huang, Sarah D., Wang, Wei, Watson, Karol, Wang, Ding and Ping, Peipei (2024). Missing Values in Longitudinal Proteome Dynamics Studies: Making a Case for Data Multiple Imputation. Journal of Proteome Research, 23 (9), 4151-4162. doi: 10.1021/acs.jproteome.4c00263
Didan, Yuliia, Ghomlaghi, Milad, Nguyen, Lan K. and Ng, Dominic C. H. (2024). Stress pathway outputs are encoded by pH-dependent clustering of kinase components. Nature Communications, 15 (1) 6614, 1-16. doi: 10.1038/s41467-024-50638-w
Nguyen-Dien, Giang Thanh, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Kozul, Keri-Lyn, Ooi, Soo Siang, Eldershaw, Denaye N, Weeratunga, Saroja, Liu, Meihan, Jones, Mathew JK, Millard, S Sean, Ng, Dominic CH, Pagano, Michele, Bonfim-Melo, Alexis, Schneider, Tobias, Komander, David, Lazarou, Michael, Collins, Brett M and Pagan, Julia K (2024). PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4. EMBO Reports, 25 (8), 3324-3347. doi: 10.1038/s44319-024-00181-y
Pandi, Boomathi, Brenman, Stella, Black, Alexander, Ng, Dominic C. M., Lau, Edward and Lam, Maggie P. Y. (2024). Tissue usage preference and intrinsically disordered region remodeling of alternative splicing derived proteoforms in the heart. Journal of Proteome Research, 23 (8), 3161-3173. doi: 10.1021/acs.jproteome.3c00789
Yan, Yu, Wang, Dean, Xin, Ruiqi, Soriano, Raine A., Ng, Dominic C. M., Wang, Wei and Ping, Peipei (2023). Protocol for the prediction, interpretation, and mutation evaluation of post-translational modification using MIND-S. Star Protocols, 4 (4) 102682, 1-10. doi: 10.1016/j.xpro.2023.102682
Yan, Yu, Jiang, Jyun-Yu, Fu, Mingzhou, Wang, Ding, Pelletier, Alexander R., Sigdel, Dibaka, Ng, Dominic C. M., Wang, Wei and Ping, Peipei (2023). MIND-S is a deep-learning prediction model for elucidating protein post-translational modifications in human diseases. Cell Reports Methods, 3 (3) 100430, 1-19. doi: 10.1016/j.crmeth.2023.100430
Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5
Rashidieh, Behnam, Shohayeb, Belal, Bain, Amanda Louise, Fortuna, Patrick R. J., Sinha, Debottam, Burgess, Andrew, Mills, Richard, Adams, Rachael C., Lopez, J. Alejandro, Blumbergs, Peter, Finnie, John, Kalimutho, Murugan, Piper, Michael, Hudson, James Edward, Ng, Dominic C. H. and Khanna, Kum Kum (2021). Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. PLoS Genetics, 17 (10) e1009334, 1-31. doi: 10.1371/journal.pgen.1009334
Ng, Dominic C. H., Ho, Uda Y. and Grounds, Miranda D. (2021). Cilia, centrosomes and skeletal muscle. International Journal of Molecular Sciences, 22 (17) 9605, 9605. doi: 10.3390/ijms22179605
Ding, Qiao, Chaplin, Justin, Morris, Matthew J., Hilliard, Massimo A., Wolvetang, Ernst, Ng, Dominic C. H. and Noakes, Peter G. (2021). TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cells. Frontiers in Cell and Developmental Biology, 9 611601, 611601. doi: 10.3389/fcell.2021.611601
Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5
Zhi, Yiqiang, Zhou, Xiaokun, Yu, Jurui, Yuan, Ling, Zhang, Hongsheng, Ng, Dominic C. H., Xu, Zhiheng and Xu, Dan (2021). Pathophysiological significance of WDR62 and JNK signaling in human diseases. Frontiers in Cell and Developmental Biology, 9 640753, 640753. doi: 10.3389/fcell.2021.640753
Ng, Dominic C.H., Richards, Dominic K., Mills, Richard J., Ho, Uda Y., Perks, Hannah L., Tucker, Callum R., Voges, Holly K., Pagan, Julia K. and Hudson, James E. (2020). Centrosome reduction promotes terminal differentiation of human cardiomyocytes. Stem Cell Reports, 15 (4), 817-826. doi: 10.1016/j.stemcr.2020.08.007
Shohayeb, Belal, Ho, Uda Y., Hassan, Halah, Piper, Michael and Ng, Dominic C. H. (2020). The spindle-associated microcephaly protein, WDR62, is required for neurogenesis and development of the hippocampus. Frontiers in Cell and Developmental Biology, 8 549353, 549353. doi: 10.3389/fcell.2020.549353
Shohayeb, Belal, Mitchell, Naomi, Millard, S. Sean, Quinn, Leonie M. and Ng, Dominic C.H. (2020). Elevated levels of Drosophila Wdr62 promote glial cell growth and proliferation through AURKA signalling to AKT and MYC. Biochimica et Biophysica Acta - Molecular Cell Research, 1867 (7) 118713, 118713. doi: 10.1016/j.bbamcr.2020.118713
Shohayeb, Belal, Ho, Uda, Yeap, Yvonne Y., Parton, Robert G., Millard, Sean S., Xu, Zhiheng, Piper, Michael and Ng, Dominic C. H. (2020). The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Human Molecular Genetics, 29 (2), 248-263. doi: 10.1093/hmg/ddz281
Moslehi, Maryam, Ng, Dominic C. H. and Bogoyevitch, Marie A. (2019). Pathogenic E2K mutation of doublecortin X (DCX) alters microtubule stabilisation and actin filament association. Biochemical and Biophysical Research Communications, 513 (3), 540-545. doi: 10.1016/j.bbrc.2019.04.005
Moslehi, Maryam, Ng, Dominic C. H. and Bogoyevitch, Marie A. (2019). Doublecortin X (DCX) serine 28 phosphorylation is a regulatory switch, modulating association of DCX with microtubules and actin filaments. Biochimica et Biophysica Acta - Molecular Cell Research, 1866 (4), 638-649. doi: 10.1016/j.bbamcr.2019.01.003
Hoque, Ashfaqul, Williamson, Nicholas A., Ameen, S. Sadia, Ciccotosto, Giuseppe D., Hossain, M. Iqbal, Oakhill, Jonathan S., Ng, Dominic C. H., Ang, Ching-Seng and Cheng, Heung-Chin (2019). Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death. Cell Death and Disease, 10 (3) 213, 213. doi: 10.1038/s41419-019-1445-0
Xu, Dan, Yao, Minghui, Wang, Yaqing, Yuan, Ling, Hoeck, Joerg D., Yu, Jingwen, Liu, Liang, Yeap, Yvonne Y. C., Zhang, Weiya, Zhang, Feng, Feng, Yinghang, Ma, Tiantian, Wang, Yujie, Ng, Dominic C. H., Niu, Xiaoyin, Su, Bing, Behrens, Axel and Xu, Zhiheng (2018). MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. Plos Biology, 16 (12) e2006613, e2006613. doi: 10.1371/journal.pbio.2006613
Woodman, Owen L., Chin, Kai Yee, Thomas, Colleen J., Ng, Dominic C. H. and May, Clive N. (2018). Flavonols and flavones - protecting against myocardial ischemia/reperfusion injury by targeting protein kinases. Current Medicinal Chemistry, 25 (34), 4402-4415. doi: 10.2174/0929867325666180326161730
Shohayeb, Belal, Diab, Mohamed, Ahmed, Mazen and Ng, Dominic Chi Hiung (2018). Factors that influence adult neurogenesis as potential therapy. Translational Neurodegeneration, 7 (1) 4, 1-19. doi: 10.1186/s40035-018-0109-9
Chin, Kai Yee, Silva, Lokugan S., Darby, Ian A., Ng, Dominic C. H. and Woodman, Owen L. (2018). Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2. International Journal of Cardiology, 254, 265-271. doi: 10.1016/j.ijcard.2017.11.101
Shohayeb, Belal, Lim, Nicholas Rui, Ho, Uda, Xu, Zhiheng, Dottori, Mirella, Quinn, Leonie and Ng, Dominic Chi Hiung (2017). The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development. Molecular Neurobiology, 55 (7), 5409-5424. doi: 10.1007/s12035-017-0778-x
Moslehi, Maryam, Ng, Dominic C. H. and Bogoyevitch, Marie A. (2017). Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus. Scientific Reports, 7 (1) 5245, 5245. doi: 10.1038/s41598-017-05340-x
Lim, Nicholas R., Shohayeb, Belal, Zaytseva, Olga, Mitchell, Naomi, Millard, S. Sean, Ng, Dominic C. H. and Quinn, Leonie M. (2017). Glial-specific functions of microcephaly protein WDR62 and interaction with the mitotic kinase AURKA are essential for Drosophila brain growth. Stem Cell Reports, 9 (1), 32-41. doi: 10.1016/j.stemcr.2017.05.015
Fife, C. M., Sagnella, S. M., Teo, W. S., Po'Uha, S. T., Byrne, F. L., Yeap, Y. Y. C., Ng, D. C. H., Davis, T. P., McCarroll, J. A. and Kavallaris, M. (2017). Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration. Intensive Care Medicine, 36 (4), 501-511. doi: 10.1038/onc.2016.220
Alshawaf, Abdulah J., Antonic, Ana, Skafidas, Efstratios, Ng, Dominic Chi-Hung and Dottori, Mirella (2017). WDR62 regulates early neural and glial progenitor specification of human pluripotent stem cells. Stem Cells International, 2017 7848932, 7848932-9. doi: 10.1155/2017/7848932
Hoque, Ashfaqul, Hossain, M. Iqbal, Ameen, S. Sadia, Ang, Ching-Seng, Williamson, Nicholas, Ng, Dominic C. H., Chueh, Anderly C., Roulston, Carli and Cheng, Heung-Chin (2016). A beacon of hope in stroke therapy - blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies. Pharmacology and Therapeutics, 160, 159-179. doi: 10.1016/j.pharmthera.2016.02.009
Lau, Edward, Cao, Quan, Ng, Dominic C. M., Bleakley, Brian J., Dincer, T. Umut, Bot, Brian M., Wang, Ding, Liem, David A., Lam, Maggie P. Y., Ge, Junbo and Ping, Peipei (2016). A large dataset of protein dynamics in the mammalian heart proteome. Scientific Data, 3 (1) ARTN 160015. doi: 10.1038/sdata.2016.15
Lim, Nicholas R., Yeap, Yvonne Y. C., Ang, Ching-Seng, Williamson, Nicholas A., Bogoyevitch, Marie A., Quinn, Leonie M. and Ng, Dominic C. H. (2016). Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation. Cell Cycle, 15 (3), 413-424. doi: 10.1080/15384101.2015.1127472
Thomas, Colleen J., Lim, Nicholas R., Kedikaetswe, Alphious, Yeap, Yvonne Y., Woodman, Owen L., Ng, Dominic C. H. and May, Clive N. (2015). Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3′,4′-dihydroxyflavonol. European Journal of Pharmacology, 758, 53-59. doi: 10.1016/j.ejphar.2015.03.054
Birnie, Kimberly A., Yip, Yan Y., Ng, Dominic C. H., Kirschner, Michaela B., Reid, Glen, Prele, Cecilia M., Musk, Arthur W. (Bill), Lee, Y. C. Gary, Thompson, Philip J., Mutsaers, Steven E. and Badrian, Bahareh (2015). Loss of miR-223 and JNK signaling contribute to elevated Stathmin in malignant pleural mesothelioma. Molecular Cancer Research, 13 (7), 1106-1118. doi: 10.1158/1541-7786.MCR-14-0442
Bell, James R., Raaijmakers, Antonia J. A., Curl, Claire L., Reichelt, Melissa E., Harding, TristanW., Bei, Aier, Ng, Dominic C. H., Erickson, Jeffrey R., Petroff, Martin Vila, Harrap, Stephen B. and Delbridge, Lea M. D. (2015). Cardiac CaMKIIδ splice variants exhibit target signaling specificity and confer sex-selective arrhythmogenic actions in the ischemic-reperfused heart. International Journal of Cardiology, 181, 288-296. doi: 10.1016/j.ijcard.2014.11.159
Lim, Nicholas R., Yeap, Yvonne Y. C., Zhao, Teresa T., Yip, Yan Y., Wong, Shu C., Xu, Dan, Ang, Ching-Seng, Williamson, Nicholas A., Xu, Zhiheng, Bogoyevitch, Marie A. and Ng, Dominic C. H. (2015). Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules. Journal of Cell Science, 128 (3), 527-540. doi: 10.1242/jcs.157537
Hossaina, M. Iqbal, Hoquel, Ashfaqul, Lessene, Guillaume, Kamaruddin, M. Aizuddin, Chu, Percy W. Y., Ng, Ivan H. W., Irtegun, Sevgi, Ng, Dominic C. H., Bogoyevitch, Marie A., Burgess, Antony W., Hill, Andrew F. and Cheng, Heung-Chin (2015). Dual role of Src kinase in governing neuronal survival. Brain Research, 1594, 1-14. doi: 10.1016/j.brainres.2014.10.040
Wang, Ding, Liem, David A., Lau, Edward, Ng, Dominic C. M., Bleakley, Brian J., Cadeiras, Martin, Deng, Mario C., Lam, Maggie P. Y. and Ping, Peipei (2014). Characterization of human plasma proteome dynamics using deuterium oxide. Proteomics Clinical Applications, 8 (7-8), 610-619. doi: 10.1002/prca.201400038
Zong, Nobel, Ping, Peipei, Lau, Edward, Choi, Howard J. H., Ng, Dominic C. M., Meyer, David, Fang, Caiyun, Li, Haomin, Wang, Ding, Zelaya, Ivette M., Yates, John R. and Lam, Maggie P. Y. (2014). Lysine ubiquitination and acetylation of human cardiac 20S proteasomes. Proteomics Clinical Applications, 8 (7-8), 590-594. doi: 10.1002/prca.201400029
Yip, Yan Y., Yeap, Yvonne Y. C., Bogoyevitch, Marie A. and Ng, Dominic C. H. (2014). Differences in c-Jun N-terminal kinase recognition and phosphorylation of closely related stathmin-family members. Biochemical and Biophysical Research Communications, 446 (1), 248-254. doi: 10.1016/j.bbrc.2014.02.101
Misheva, Mariya, Kaur, Gurpreet, Ngoei, Kevin R. W., Yeap, Yvonne Y., Ng, Ivan H. W., Wagstaff, Kylie M., Ng, Dominic C. H., Jans, David A. and Bogoyevitch, Marie A. (2014). Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress. BBA- Molecular Cell Research, 1843 (2), 253-264. doi: 10.1016/j.bbamcr.2013.10.017
Yip, Yan Y., Yeap, Yvonne Y. C., Bogoyevitch, Marie A. and Ng, Dominic C. H. (2014). CAMP-dependent protein kinase and c-jun n-terminal kinase mediate stathmin phosphorylation for the maintenance of interphase microtubules during osmotic stress. Journal of Biological Chemistry, 289 (4), 2157-2169. doi: 10.1074/jbc.M113.470682
Lim, Nicholas R., Thomas, Colleen J., Silva, Lokugan S., Yeap, Yvonne Y., Yap, Suwan, Bell, James R., Delbridge, Lea M. D., Bogoyevitch, Marie A., Woodman, Owen L., Williams, Spencer J., May, Clive N. and Ng, Dominic C. H. (2013). Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38MAPK signalling involves CaMKII inhibition. Biochemical Journal, 456 (2), 149-161. doi: 10.1042/BJ20121538
Ngoei, Kevin R. W., Ng, Dominic C. H., Gooley, Paul R., Fairlie, David P., Stoermer, Martin J. and Bogoyevitch, Marie A. (2013). Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1834 (6), 1077-1088. doi: 10.1016/j.bbapap.2013.02.001
Hossain, M. Iqbal, Roulston, Carli L., Kamaruddin, M. Aizuddin, Chu, Percy W. Y., Ng, Dominic C. H., Dusting, Gregory J., Bjorge, Jeffrey D., Williamson, Nicholas A., Fujita, Donald J., Cheung, Steve N., Chan, Tung O., Hill, Andrew F. and Cheng, Heung-Chin (2013). A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity. Journal of Biological Chemistry, 288 (14), 9696-9709. doi: 10.1074/jbc.M112.419713
Bogoyevitch, Marie A., Yeap, Yvonne Y. C., Qu, Zhengdong, Ngoei, Kevin R., Yip, Yan Y., Zhao, Teresa T., Heng, Julian I. and Ng, Dominic C. H. (2012). WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression. Journal of Cell Science, 125 (21), 5096-5109. doi: 10.1242/jcs.107326
Ng, Ivan H. W., Ng, Dominic C. H., Jans, David A. and Bogoyevitch, Marie A. (2012). Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes. Biochemical Journal, 447 (1), 125-136. doi: 10.1042/BJ20120941
Ramdzan, Yasmin M., Polling, Saskia, Chia, Cheryl P. Z., Ng, Ivan H. W., Ormsby, Angelique R., Croft, Nathan P., Purcell, Anthony W., Bogoyevitch, Marie A., Ng, Dominic C. H., Gleeson, Paul A. and Hatters, Danny M. (2012). Tracking protein aggregation and mislocalization in cells with flow cytometry. Nature Methods, 9 (5), 467-470. doi: 10.1038/nmeth.1930
Waardenberg, Ashley J., Bernardo, Bianca C., Ng, Dominic C. H., Shepherd, Peter R., Cemerlang, Nelly, Sbroggio, Mauro, Wells, Christine A., Dalrymple, Brian P., Brancaccio, Mara, Lin, Ruby C. Y. and McMullen, Julie R. (2011). Phosphoinositide 3-Kinase (PI3K(p110 alpha))directly regulates key components of the Z-disc and cardiac structure. Journal of Biological Chemistry, 286 (35), 30837-30846. doi: 10.1074/jbc.M111.271684
Thomas, Colleen J., Ng, Dominic C. H., Patsikatheodorou, Nikolas, Limengka, Yuliardy, Lee, Matthew W. K., Darby, Ian A., Woodman, Owen L. and May, Clive N. (2011). Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK. European Journal of Pharmacology, 658 (2-3), 160-167. doi: 10.1016/j.ejphar.2011.02.041
Ngoei, Kevin R. W., Catimel, Bruno, Church, Nicole, Lio, Daisy S., Dogovski, Con, Perugini, Matthew A., Watt, Paul M., Cheng, Heung-Chin, Ng, Dominic C. H. and Bogoyevitch, Marie A. (2011). Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide. Biochemical Journal, 434 (3), 399-413. doi: 10.1042/BJ20101244
Ng, Dominic C. H., Ng, Ivan H. W., Yeap, Yvonne Y. C., Badrian, Bahareh, Tsoutsman, Tatiana, McMullen, Julie R., Semsarian, Christopher and Bogoyevitch, Marie A. (2011). Opposing actions of extracellular signal-regulated kinase (ERK) and signal transducer and activator of transcription 3 (STAT3) in regulating microtubule stabilization during cardiac hypertrophy. Journal of Biological Chemistry, 286 (2), 1576-1587. doi: 10.1074/jbc.M110.128157
Meyerowitz, Jodi, Parker, Sarah J., Vella, Laura J., Ng, Dominic C. H., Price, Katherine A., Liddell, Jeffrey R., Caragounis, Aphrodite, Li, Qiao-Xin, Masters, Colin L., Nonaka, Takashi, Hasegawa, Masato, Bogoyevitch, Marie A., Kanninen, Katja M., Crouch, Peter J. and White, Anthony R. (2011). C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress. Molecular Neurodegeneration, 6 (57) 57. doi: 10.1186/1750-1326-6-57
Yeap, Yvonne Y. C., Ng, Ivan H. W., Badrian, Bahareh, Nguyen, Tuong-Vi, Yip, Yan Y., Dhillon, Amardeep S., Mutsaers, Steven E., Silke, John, Bogoyevitch, Marie A. and Ng, Dominic C. H. (2010). c-Jun N-terminal kinase/c-Jun inhibits fibroblast proliferation by negatively regulating the levels of stathmin/oncoprotein 18. Biochemical Journal, 430 (2), 345-354. doi: 10.1042/BJ20100425
Ng, Dominic C. H., Zhao, Teresa T., Yeap, Yvonne Y. C., Ngoei, Kevin R. and Bogoyevitch, Marie A. (2010). c-Jun N-terminal kinase phosphorylation of stathmin confers protection against cellular stress. Journal of Biological Chemistry, 285 (37), 29001-29013. doi: 10.1074/jbc.M110.128454
Bogoyevitch, Marie A., Ngoei, Kevin R. W., Zhao, Teresa T., Yeap, Yvonne Y. C. and Ng, Dominic C. H. (2010). c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1804 (3), 463-475. doi: 10.1016/j.bbapap.2009.11.002
Ng, Dominic C. H., Lim, Cheh P., Lin, Bao H., Zhang, Tong and Cao, Xinmin (2010). SCG10-like protein (SCLIP) is a STAT3-interacting protein involved in maintaining epithelial morphology in MCF-7 breast cancer cells. Biochemical Journal, 425 (1), 95-105. doi: 10.1042/BJ20091213
Teng, Terk Shin, Lin, Baohong, Manser, Ed, Ng, Dominic Chi Hiung and Cao, Xinmin (2009). Stat3 promotes directional cell migration by regulating Rac1 activity via its activator βPIX. Journal of Cell Science, 122 (22), 4150-4159. doi: 10.1242/jcs.057109
Tsoutsman, Tatiana, Kelly, Matthew, Ng, Dominic C. H., Tan, Ju-En, Tu, Emily, Lam, Lien, Bogoyevitch, Marie A., Seidman, Christine E., Seidman, J. G. and Semsarian, Christopher (2008). Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy. Circulation, 117 (14), 1820-1831. doi: 10.1161/CIRCULATIONAHA.107.755777
Ng, Dominic C. H., Gebski, Bijanka L., Grounds, Miranda D. and Bogoyevitch, Marie A. (2008). Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition. Cell Motility and the Cytoskeleton, 65 (1), 40-58. doi: 10.1002/cm.20242
Ng, Dominic Chi Hiung, Lin, Bao Hong, Lim, Cheh Peng, Huang, Guochang, Zhang, Tong, Poli, Valerie and Cao, Xinmin (2006). Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. Journal of Cell Biology, 172 (2), 245-257. doi: 10.1083/jcb.200503021
Grounds, Haslett R., Ng, Dominic C. H. and Bogoyevitch, Marie A. (2005). Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology. Journal of Cellular Biochemistry, 95 (3), 529-542. doi: 10.1002/jcb.20441
Huang, Guochang, Lu, Hao, Hao, Aijun, Ng, Dominic C. H., Ponniah, Sathivel, Guo, Ke, Lufei, Chengchen, Zeng, Qi and Cao, Xinmin (2004). GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Molecular and Cellular Biology, 24 (19), 8447-8456. doi: 10.1128/MCB.24.19.8447-8456.2004
Ng, Dominic C.H., Court, Naomi W., Dos Remedios, Cristobal G. and Bogoyevitch, Marie A. (2003). Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts. Cardiovascular Research, 57 (2), 333-346. doi: 10.1016/S0008-6363(02)00664-8
Bogoyevitch, Marie A., Kendrick, Tulene S., Ng, Dominic C.H. and Barr, Renae K. (2002). Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery. DNA and Cell Biology, 21 (12), 879-894. doi: 10.1089/104454902762053846
Bogojevitch, Marie A., Thien, Marilyn and Ng, Dominic C. H. (2001). Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid. Journal of Biochemistry and Molecular Biology, 34 (6), 517-525.
Ng, Dominic C. H., Long, Carlin S. and Bogoyevitch, Marie A. (2001). A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology. Journal of Biological Chemistry, 276 (31), 29490-29498. doi: 10.1074/jbc.M100699200
Ng, Dominic C. H. and Bogoyevitch, Marie A. (2000). The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3. Journal of Biological Chemistry, 275 (52), 40856-40866. doi: 10.1074/jbc.M004639200
Bogoyevitch, Marie A., Ng, Dominic C.H., Court, Naomi W., Draper, Karen A., Dhillon, Amardeep and Abas, Lindy (2000). Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 32 (8), 1469-1480. doi: 10.1006/jmcc.2000.1187