School of Biomedical Sciences

Dr Cedric Lamboley

Project Manager
School of Biomedical Sciences

Cedric is part of the Launikonis Group - Muscle research.

Publications

Journal Articles (28)
Conference Papers (4)

Journal Articles

Meizoso-Huesca, Aldo, Lamboley, Cedric R., Krycer, James R., Hodson, Mark P., Hudson, James E. and Launikonis, Bradley S. (2025). Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression. Nature Communications, 16 (1) 3056, 3056. doi: 10.1038/s41467-025-58393-2
Pearce, Luke, Meizoso‐Huesca, Aldo, Seng, Crystal, Lamboley, Cedric R., Singh, Daniel P. and Launikonis, Bradley S. (2023). Ryanodine receptor activity and store‐operated Ca 2+ entry: critical regulators of Ca 2+ content and function in skeletal muscle. The Journal of Physiology, 601 (19), 4183-4202. doi: 10.1113/jp279512
Maxwell, Michael J., Thekkedam, Chris, Lamboley, Cedric, Chin, Yanni K.-Y., Crawford, Theo, Smith, Jennifer J., Liu, Junyu, Jia, Xinying, Vetter, Irina, Laver, Derek R., Launikonis, Bradley S., Dulhunty, Angela, Undheim, Eivind A. B. and Mobli, Mehdi (2023). A bivalent remipede toxin promotes calcium release via ryanodine receptor activation. Nature Communications, 14 (1) 1036, 1-13. doi: 10.1038/s41467-023-36579-w
Singh, Daniel P., Pearce, Luke, Choi, Rocky H., Meizoso-Huesca, Aldo, Wette, Stefan G., Scott, John W., Lamboley, Cedric R., Murphy, Robyn M. and Launikonis, Bradley S. (2023). Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals. Proceedings of the National Academy of Sciences, 120 (4) e2117503120, 1-12. doi: 10.1073/pnas.2117503120
Seng, Crystal, Pearce, Luke, Meizoso-Huesca, Aldo, Singh, Daniel P., Murphy, Robyn M., Lamboley, Cedric and Launikonis, Bradley S. (2022). Tiny changes in cytoplasmic [Ca2+] cause large changes in mitochondrial Ca2+: what are the triggers and functional implications?. American Journal of Physiology-Cell Physiology, 323 (4), C1285-C1289. doi: 10.1152/ajpcell.00092.2022
Lamboley, Cedric R., Pearce, Luke, Seng, Crystal, Meizoso-Huesca, Aldo, Singh, Daniel P., Frankish, Barnaby P., Kaura, Vikas, Lo, Harriet P., Ferguson, Charles, Allen, Paul D., Hopkins, Philip M., Parton, Robert G., Murphy, Robyn M., van der Poel, Chris, Barclay, Christopher J. and Launikonis, Bradley S. (2021). Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle. Science Advances, 7 (44) eabi7166, 1-15. doi: 10.1126/sciadv.abi7166
Lamboley, Cedric R., Rouffet, David M., Dutka, Travis L., McKenna, Michael J. and Lamb, Graham D. (2020). Effects of high-intensity intermittent exercise on the contractile properties of human type I and type II skeletal muscle fibers. Journal of Applied Physiology, 128 (5), 1207-1216. doi: 10.1152/japplphysiol.00014.2020
Watanabe, Daiki, Lamboley, Cedric R. and Lamb, Graham D. (2019). Effects of S-glutathionylation on the passive force-length relationship in skeletal muscle fibres of rats and humans. Journal of Muscle Research and Cell Motility, 41 (2-3), 239-250. doi: 10.1007/s10974-019-09563-5
Watanabe, Daiki, Dutka, Travis L., Lamboley, Cedric R. and Lamb, Graham D. (2019). Skeletal muscle fibre swelling contributes to force depression in rats and humans: a mechanically-skinned fibre study. Journal of Muscle Research and Cell Motility, 40 (3-4), 343-351. doi: 10.1007/s10974-019-09521-1
Lamboley, Cedric R., Xu, Hongyang, Dutka, Travis L., Hanson, Erik D., Hayes, Alan, Violet, John A., Murphy, Robyn M. and Lamb, Graham D. (2018). Effect of androgen deprivation therapy on the contractile properties of type I and type II skeletal muscle fibres in men with non-metastatic prostate cancer. Clinical and Experimental Pharmacology and Physiology, 45 (2), 146-154. doi: 10.1111/1440-1681.12873
Dutka, T. L., Mollica, J. P., Lamboley, C. R., Weerakkody, V. C., Greening, D. W., Posterino, G. S., Murphy, R. M. and Lamb, G. D. (2017). S-nitrosylation and S-glutathionylation of Cys134 on troponin I have opposing competitive actions on Ca2+ sensitivity in rat fast-twitch muscle fibers. American Journal of Physiology: Cell Physiology, 312 (3), C316-C327. doi: 10.1152/ajpcell.00334.2016
Lamboley, C. R., Wyckelsma, V. L., Perry, B. D., McKenna, M. J. and Lamb, G. D. (2016). Effect of 23-day muscle disuse on sarcoplasmic reticulum Ca2+ properties and contractility in human type i and type II skeletal muscle fibers. Journal of Applied Physiology, 121 (2), 483-492. doi: 10.1152/japplphysiol.00337.2016
Wyckelsma, Victoria L., McKenna, Michael J., Levinger, Itamar, Petersen, Aaron C., Lamboley, Cedric R. and Murphy, Robyn M. (2016). Cell specific differences in the protein abundances of GAPDH and Na+,K+-ATPase in skeletal muscle from aged individuals. Experimental Gerontology, 75, 8-15. doi: 10.1016/j.exger.2015.12.010
Lamboley, C. R., Wyckelsma, V. L., Mckenna, M. J., Murphy, R. M. and Lamb, G. D. (2016). Ca2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans. Journal of Physiology, 594 (2), 469-481. doi: 10.1113/JP271382
Lamboley, C. R., Wyckelsma, V. L., Dutka, T. L., McKenna, M. J., Murphy, R. M. and Lamb, G. D. (2015). Contractile properties and sarcoplasmic reticulum calcium content in type I and type II skeletal muscle fibres in active aged humans. Journal of Physiology, 593 (11), 2499-2514. doi: 10.1113/JP270179
Wyckelsma, V. L., McKenna, M. J., Serpiello, F. R., Lamboley, C. R., Aughey, R. J., Stepto, N. K., Bishop, D. J. and Murphy, R. M. (2015). Single-fiber expression and fiber-specific adaptability to short-term intense exercise training of Na+-K+-ATPaseα- and α-isoforms in human skeletal muscle. Journal of Applied Physiology, 118 (6), 699-706. doi: 10.1152/japplphysiol.00419.2014
Lamboley, Cédric R. H., Guena, Sandrine A. Kake, Touré, Fatou, Hébert, Camille, Yaddaden, Louiza, Nadeau, Stephanie, Bouchard, Patrice, Wei-LaPierre, Lan, Lainé, Jean, Rousseau, Eric C., Frenette, Jérôme, Protasi, Feliciano, Dirksen, Robert T. and Pape, Paul C. (2015). New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin. Journal of General Physiology, 145 (2), 127-153. doi: 10.1085/jgp.201411250
Dutka, T. L., Lamboley, C. R., Murphy, R. M. and Lamb, G. D. (2014). Acute effects of taurine on sarcoplasmic reticulum Ca2+ accumulation and contractility in human type i and type II skeletal muscle fibers. Journal of Applied Physiology, 117 (7), 797-805. doi: 10.1152/japplphysiol.00494.2014
Lamboley, C. R., Murphy, R. M., Mckenna, M. J. and Lamb, G. D. (2014). Sarcoplasmic reticulum Ca2+ uptake and leak properties, and SERCA isoform expression, in type I and type II fibres of human skeletal muscle. Journal of Physiology, 592 (6), 1381-1395. doi: 10.1113/jphysiol.2013.269373
Lamboley, C. R., Murphy, R. M., Mckenna, M. J. and Lamb, G. D. (2013). Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres. Journal of Physiology, 591 (23), 6053-6068. doi: 10.1113/jphysiol.2013.265900
Fénelon, Karine, Lamboley, Cédric R.H., Carrier, Nicole and Pape, Paul C. (2012). Calcium buffering properties of sarcoplasmic reticulum and calcium-induced Ca2+ release during the quasi-steady level of release in twitch fibers from frog skeletal muscle. Journal of General Physiology, 140 (4), 403-419. doi: 10.1085/jgp.201110730
Dutka, T. L., Lamboley, C. R., McKenna, M. J., Murphy, R. M. and Lamb, G. D. (2012). Effects of carnosine on contractile apparatus Ca 2+ sensitivity and sarcoplasmic reticulum Ca 2+ release in human skeletal muscle fibers. Journal of Applied Physiology, 112 (5), 728-736. doi: 10.1152/japplphysiol.01331.2011
Mollica, J. P., Dutka, T. L., Merry, T. L., Lamboley, C. R., Mcconell, G. K., Mckenna, M. J., Murphy, R. M. and Lamb, G. D. (2012). S-Glutathionylation of troponin I (fast) increases contractile apparatus Ca2+ sensitivity in fast-twitch muscle fibres of rats and humans. Journal of Physiology, 590 (6), 1443-1463. doi: 10.1113/jphysiol.2011.224535
Murphy, Robyn M., Vissing, Kristian, Latchman, Heidy, Lamboley, Cedric, McKenna, Michael J., Overgaard, Kristian and Lamb, Graham D. (2011). Activation of skeletal muscle calpain-3 by eccentric exercise in humans does not result in its translocation to the nucleus or cytosol. Journal of Applied Physiology, 111 (5), 1448-1458. doi: 10.1152/japplphysiol.00441.2011
Lamboley, Cédric R.H. and Pape, Paul C. (2011). The concentration of free Ca2+ in the sarcoplasmic reticulum of frog cut twitch skeletal muscle fibers estimated with tetramethylmurexide. Cell Calcium, 50 (6), 530-547. doi: 10.1016/j.ceca.2011.09.001
Goulet, Eric D. B., Rousseau, Stéphane F., Lamboley, Cédric R. H., Plante, Gérard E. and Dionne, Isabelle J. (2008). Pre-exercise hyperhydration delays dehydration and improves endurance capacity during 2 h of cycling in a temperate climate. Journal of Physiological Anthropology, 27 (5), 263-271. doi: 10.2114/jpa2.27.263
Pape, Paul C., Fénelon, Karine, Lamboley, Cédric R.H. and Stachura, Dorothy (2007). Role of calsequestrin evaluated from changes in free and total calcium concentrations in the sarcoplasmic reticulum of frog cut skeletal muscle fibres. Journal of Physiology, 581 (1), 319-367. doi: 10.1113/jphysiol.2006.126474
Lamboley, Cédric R.H., Royer, Donald and Dionne, Isabelle J. (2007). Effects of β-hydroxy-β-methylbutyrate on aerobic-performance components and body composition in college students. International Journal of Sport Nutrition and Exercise Metabolism, 17 (1), 56-69. doi: 10.1123/ijsnem.17.1.56

Conference Papers

Huesca, Aldo Meizoso, Choi, Rocky, Lamboley, Cedric, Beard, Nicole A., Blackmore, Daniel and Launikonis, Bradley S. (2025). BPS2025 - Ryanodine receptor Ca2+ leak signaling remains functionally intact and regulates energy expenditure in sedentary, aged mouse muscle. BPS2025, Los Angeles, CA, United States, 15 - 19 February 2025. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2024.11.1540
Lamboley, Cedric R., Pearce, Luke and Launikonis, Bradley S. (2020). Total Calcium Content of Sarcoplasmic Reticulum and Mitochondria in Ryanodine Receptor Variant Muscle. In: 64th Annual Meeting of the Biophysical Society, San Diego, CA United States, (98A-99A). 15-19 February 2020.
Kake-Guena, Sandrine A., Lamboley, Cedric R. H., Bouchard, Patrice, Frenette, Jerome, Rousseau, Eric, Dirksen, Robert T., Protasi, Feliciano and Pape, Paul C. (2014). New Method for Determining the Total Calcium Content of Tissue Applied to Whole Skeletal Muscles from Mice with and Without Calsequestrin Knocked Out. 58th Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 15-19, 2014. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2013.11.4033
Lamboley, Cedric R. H., Gyurkovics, Gabor and Pape, Paul C. (2013). The Rapid Repolarization of the Action Potential in Twitch Skeletal Muscle Fibers from Frog is due Almost Entirely to a Calcium-Activated K Current. 57th Annual Meeting of the Biophysical-Society, Philadelphia Pa, Feb 02-06, 2013. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2012.11.1623