Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KAV, Tae H, Sadeghi M, Castro J, O’Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich a-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angew. Chem. Int. Ed. (2016) 55, 4692-4696.

Grishin AA*, Cuny H*, Hung A*, Clark RJ*, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ, Identifying key amino acid residues that affect alpha-conotoxin AuIB inhibition of alpha3beta4 nicotinic acetylcholine receptors, J. Biol. Chem. (2013) 288, 34428-34442.

Clark RJ#, Tan C, Preza GC, Nemeth E, Ganz T, Craik DJ, Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chem. Biol. (2011) 18, 336-343.

Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ and Craik DJ, The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angewandte Chemie (2010) 49, 6545-6548

Clark R J, Daly N L, Craik D J. Structural plasticity of the cyclic cystine knot framework: implications for biological activity and drug design. Biochemical J (2006) 394, 85-93

*Clark R J, Fischer H, Dempster L, Daly N L, Rosengren K J, Nevin S T, Daly N L, Meunier F A, Adams D J, Craik D J. Engineering stable peptide toxins by means of backbone cyclisation: stabilisation of the a-conotoxin MII. Proc. Nat. Acad. Sci. (2005) 102, 13767-13772.

Rosengren KJ, Clark RJ, Daly NL, Göransson U, Jones A, Craik DJ. Microcin J25 has a threaded sidechain-to-backbone. JACS (2003) 125, 12464-12474.

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