Dr Prajakta Kulkarni
Postdoctoral Research Fellow
School of Biomedical Sciences
Prajakta is part of the Pagan group which studies targeted protein degradation.
Journal Articles
Nguyen‐Dien, Giang Thanh, Kozul, Keri‐Lyn, Cui, Yi, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Ooi, Soo Siang, Marzio, Antonio, Carrodus, Nissa, Zuryn, Steven, Pagano, Michele, Parton, Robert G, Lazarou, Michael, Millard, S Sean, Taylor, Robert W, Collins, Brett M, Jones, Mathew JK and Pagan, Julia K (2023). FBXL4
suppresses mitophagy by restricting the accumulation of
NIX
and
BNIP3
mitophagy receptors. The EMBO Journal. doi: 10.15252/embj.2022112767
Makhoul, Christian, Gosavi, Prajakta and Gleeson, Paul A. (2019). Golgi dynamics: The morphology of the mammalian Golgi apparatus in health and disease. Frontiers in Cell and Developmental Biology, 7, 1-7. doi: 10.3389/fcell.2019.00112
Makhoul, Christian, Gosavi, Prajakta, Duffield, Regina, Delbridge, Bronwen, Williamson, Nicholas A. and Gleeson, Paul A. (2019). Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Molecular Biology of the Cell, 30 (3), 370-386. doi: 10.1091/mbc.e18-05-0313
Makhoul, Christian, Gosavi, Prajakta and Gleeson, Paul A. (2018). The Golgi architecture and cell sensing. Biochemical Society Transactions, 46 (5), 1063-1072. doi: 10.1042/bst20180323
Gosavi, Prajakta, Houghton, Fiona J., McMillan, Paul J., Hanssen, Eric and Gleeson, Paul A. (2018). The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. Journal of Cell Science, 131 (3), 1-15. doi: 10.1242/jcs.211987
Gosavi, Prajakta (2018). First person - Prajakta Gosavi. Journal of Cell Science, 131 (3), 1-2. doi: 10.1242/jcs.215640
Gurjar, Mansa, Raychaudhuri, Kumarkrishna, Mahadik, Snehal, Reddy, Divya, Atak, Apurva, Shetty, Trupti, Rao, Kruthi, Karkhanis, Mansi S., Gosavi, Prajakta, Sehgal, Lalit, Gupta, Sanjay and Dalal, Sorab N. (2018). Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin2. Biochemical and Biophysical Research Communications, 495 (1), 768-774. doi: 10.1016/j.bbrc.2017.11.085
Gosavi, Prajakta, Kundu, Samrat T., Khapare, Nileema, Sehgal, Lalit, Karkhanis, Mansi S. and Dalal, Sorab N. (2010). E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly. Cellular and Molecular Life Sciences, 68 (8), 1439-1454. doi: 10.1007/s00018-010-0531-3
Kundu, Samrat T., Gosavi, Prajakta, Khapare, Nileema, Patel, Rachana, Hosing, Amol S., Maru, Girish B., Ingle, Arvind, DeCaprio, James A. and Dalal, Sorab N. (2008). Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis. International Journal of Cancer, 123 (10), 2303-2314. doi: 10.1002/ijc.23797
Conference Paper
Gurjar, M. C., Raychaudhuri, K., Mahadik, S., Atak, A., Sehgal, L., Karkhanis, M., Gosavi, P. and Dalal, S. N. (2014). Plakophilin3 expression results in an increase in the level of desmosomal components and the formation of calcium independent desmosomes. FEBS EMBO 2014 Conference, Paris, France, 30 August - 4 September 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.