Associate Professor Mark Bellingham
Associate Professor
School of Biomedical Sciences
+61 7 336 53122
Associate Professor Mark Bellingham heads the neurobiology of motor behaviour lab, and is a network member of the MND Collective at UQ.
Researcher biography
Electrophysiology of synaptic transmission, ion currents and central pattern generation in CNS neurones.
Current research focuses on the electrophysiology of central nervous system neurones using various in vitro slice and in vivo preparations, patch clamp techniques, imaging, molecular biology and computer modelling.
Projects include :
- Neurobiology of motor control
- Motor neuron disease
- Synaptic transmission in the cochlear nucleus
- Potassium currents in the brainstem and cerebellum
- Rhythmic control of breathing movements
Book Chapters
Ngo, Shyuan T. and Bellingham, Mark C. (2013). Neurophysiological recording of the compound muscle action potential for motor unit number estimation in mice. Stimulation and inhibition of neurons. (pp. 225-235) edited by Pilowsky, Paul M., Farnham, Melissa M. J. and Fong, Angelina Y.. New York, NY United States: Humana Press. doi: 10.1007/978-1-62703-233-9_13
Kanjhan, Refik and Bellingham, Mark C. (2013). Neurobiotin electroporation for combined structural and functional analysis of neurons in developing mouse brain slices. Stimulation and inhibition of neurons. (pp. 151-165) edited by Pilowsky, Paul M., Farnham, Melissa M. J. and Fong, Angelina Y.. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-233-9_9
Bellingham, Mark C. (2013). Pharmacological dissection of G protein-mediated second messenger cascades in neurons. Stimulation and inhibition of neurons. (pp. 61-106) edited by Pilowsky, Paul M., Farnham, Melissa M. J. and Fong, Angelina Y.. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-233-9_5
Berger, A. J., Bayliss, D. A., Bellingham, M. C., Umemiya, M. and Viana, F. (1995). Postnatal development of hypoglossal motoneuron intrinsic properties. Control of the Cardiovascular and Respiratory Systems in Health and Disease. (pp. 63-71) edited by C. Tissa Kappagoda and Marc P. Kaufman. Singapore, Singapore: Springer Singapore. doi: 10.1007/978-1-4615-1895-2_7
Journal Articles
Cheung, Sang Won, Willis, Emily F., Simmons, David G., Bellingham, Mark C. and Noakes, Peter G. (2024). Phagocytosis of aggrecan-positive perineuronal nets surrounding motor neurons by reactive microglia expressing MMP-9 in TDP-43Q331K ALS model mice. Neurobiology of Disease, 200 106614, 1-13. doi: 10.1016/j.nbd.2024.106614
Fogarty, Matthew J., Drieberg-Thompson, Joy R., Bellingham, Mark C. and Noakes, Peter G. (2024). Timeline of hypoglossal motor neuron death and intrinsic tongue muscle denervation in high-copy number SOD1G93A mice. Frontiers in Neurology, 15 1422943, 1-7. doi: 10.3389/fneur.2024.1422943
Cheung, Sang Won, Bhavnani, Ekta, Simmons, David G., Bellingham, Mark C. and Noakes, Peter G. (2024). Perineuronal nets are phagocytosed by MMP‐9 expressing microglia and astrocytes in the SOD1G93A ALS mouse model. Neuropathology and Applied Neurobiology, 50 (3) e12982, 1-19. doi: 10.1111/nan.12982
Cheung, Sang Won, Bhavnani, Ekta, Simmons, David G., Bellingham, Mark C. and Noakes, Peter G. (2024). Cover Image, Volume 50, Issue 3. Neuropathology and Applied Neurobiology, 50 (3). doi: 10.1111/nan.12993
Qian, Lei, Rawashdeh, Oliver, Kasas, Leda, Milne, Michael R., Garner, Nicholas, Sankorrakul, Kornraviya, Marks, Nicola, Dean, Matthew W., Kim, Pu Reum, Sharma, Aanchal, Bellingham, Mark C. and Coulson, Elizabeth J. (2022). Cholinergic basal forebrain degeneration due to sleep-disordered breathing exacerbates pathology in a mouse model of Alzheimer’s disease. Nature Communications, 13 (1) 6543, 1-18. doi: 10.1038/s41467-022-33624-y
Bolneo, Erika, Chau, Pak Yan S., Noakes, Peter G. and Bellingham, Mark C. (2022). Investigating the role of GABA in neural development and disease using mice lacking GAD67 or VGAT genes. International Journal of Molecular Sciences, 23 (14) 7965, 1-18. doi: 10.3390/ijms23147965
Gaik, Monika, Kojic, Marija, Stegeman, Megan R., Öncü‐Öner, Tülay, Kościelniak, Anna, Jones, Alun, Mohamed, Ahmed, Chau, Pak Yan Stefanie, Sharmin, Sazia, Chramiec‐Głąbik, Andrzej, Indyka, Paulina, Rawski, Michał, Biela, Anna, Dobosz, Dominika, Millar, Amanda, Chau, Vann, Ünalp, Aycan, Piper, Michael, Bellingham, Mark C., Eichler, Evan E., Nickerson, Deborah A., Güleryüz, Handan, Abbassi, Nour El Hana, Jazgar, Konrad, Davis, Melissa J., Mercimek‐Andrews, Saadet, Cingöz, Sultan, Wainwright, Brandon J. and Glatt, Sebastian (2022). Functional divergence of the two Elongator subcomplexes during neurodevelopment. EMBO Molecular Medicine, 14 (7) e15608, e15608. doi: 10.15252/emmm.202115608
Parker, Sandra E., Bellingham, Mark C. and Woodruff, Trent M. (2022). Complement drives circuit modulation in the adult brain. Progress in Neurobiology, 214 102282, 102282. doi: 10.1016/j.pneurobio.2022.102282
Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2021). Size-dependent dendritic maladaptations of hypoglossal motor neurons in SOD1G93A mice. Anatomical Record, 304 (7), 1562-1581. doi: 10.1002/ar.24542
Sharmin, Sazia, Pradhan, Jonu, Zhang, Zhe, Bellingham, Mark, Simmons, David and Piper, Michael (2021). Perineuronal net abnormalities in Slc13a4+/- mice are rescued by postnatal administration of N-acetylcysteine. Experimental Neurology, 342 113734, 1-16. doi: 10.1016/j.expneurol.2021.113734
Pradhan, Jonu and Bellingham, Mark C. (2021). Neurophysiological mechanisms underlying cortical hyper-excitability in amyotrophic lateral sclerosis: a review. Brain Sciences, 11 (5) 549, 10-10. doi: 10.3390/brainsci11050549
Klenowski, Paul M., Fogarty, Matthew J., Drieberg-Thompson, Joy R., Bellingham, Mark C. and Bartlett, Selena E. (2021). Reduced Inhibitory Inputs On Basolateral Amygdala Principal Neurons Following Long-Term Alcohol Consumption. Neuroscience, 452, 219-227. doi: 10.1016/j.neuroscience.2020.10.039
Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2019). Size-dependent vulnerability of lumbar motor neuron dendritic degeneration in SOD1(G93A) mice. The Anatomical Record, 303 (5) ar.24255, 1455-1471. doi: 10.1002/ar.24255
Pradhan, Jonu, Noakes, Peter G. and Bellingham, Mark C. (2019). The Role of Altered BDNF/TrkB Signaling in Amyotrophic Lateral Sclerosis. Frontiers in Cellular Neuroscience, 13 368, 368. doi: 10.3389/fncel.2019.00368
Thakre, Prajwal P. and Bellingham, Mark C. (2019). Capsaicin causes robust reduction in glycinergic transmission to rat hypoglossal motor neurons via a TRPV1-independent mechanism. Journal of Neurophysiology, 121 (4), 1535-1542. doi: 10.1152/jn.00059.2019
Lau, Cora, Thakre, Prajwal P. and Bellingham, Mark C. (2019). Alfaxalone Causes Reduction of Glycinergic IPSCs, but Not Glutamatergic EPSCs, and Activates a Depolarizing Current in Rat Hypoglossal Motor Neurons. Frontiers in Cellular Neuroscience, 13 100, 100. doi: 10.3389/fncel.2019.00100
Hou, Lili, Bellingham, Mark C., Huang, Yong, Zhang, Pengyu, Zhou, Xin and Zhang, Min (2019). Central inspiratory activity rhythmically activates synaptic currents of airway vagal preganglionic neurons in neonatal rats. Neuroscience Letters, 694, 231-237. doi: 10.1016/j.neulet.2018.11.024
Klenowski, Paul M., Wright, Sophie E., Mu, Erica W.H., Noakes, Peter G., Lavidis, Nickolas A., Bartlett, Selena E., Bellingham, Mark C. and Fogarty, Matthew J. (2017). Investigating methodological differences in the assessment of dendritic morphology of basolateral amygdala principal neurons – a comparison of Golgi-Cox and neurobiotin electroporation techniques. Brain Sciences, 7 (12) 165, 1-12. doi: 10.3390/brainsci7120165
Thakre, Prajwal P. and Bellingham, Mark C. (2017). Capsaicin enhances glutamatergic synaptic transmission to neonatal rat hypoglossal motor neurons via a TRPV1-independent mechanism. Frontiers in Cellular Neuroscience, 11 (383) 383, 383. doi: 10.3389/fncel.2017.00383
Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2017). Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model. Frontiers in Neuroscience, 11 (NOV) 609, 1-16. doi: 10.3389/fnins.2017.00609
Shariff, Masroor, Klenowski, Paul, Morgan, Michael, Patkar, Omkar, Mu, Erica, Bellingham, Mark, Belmer, Arnauld and Bartlett, Selena E. (2017). Binge-like sucrose consumption reduces the dendritic length and complexity of principal neurons in the adolescent rat basolateral amygdala. PLoS One, 12 (8) e0183063, e0183063. doi: 10.1371/journal.pone.0183063
Fogarty, Matthew J., Kanjhan, Refik, Yanagawa, Yuchio, Noakes, Peter G. and Bellingham, Mark C. (2017). Alterations in hypoglossal motor neurons due to GAD67 and VGAT deficiency in mice. Experimental Neurology, 289, 117-127. doi: 10.1016/j.expneurol.2016.12.004
Klenowski, Paul M., Fogarty, Matthew J., Shariff, Masroor, Belmer, Arnauld, Bellingham, Mark C. and Bartlett, Selena E. (2016). Increased synaptic excitation and abnormal dendritic structure of prefrontal cortex layer V pyramidal neurons following prolonged binge-like consumption of ethanol. eNeuro, 3 (6) e0248, ENEURO.0248-16.2016. doi: 10.1523/eneuro.0248-16.2016
Fogarty, Matthew J., Klenowski, Paul M., Lee, John D., Drieberg-Thompson, Joy R., Bartlett, Selena E., Ngo, Shyuan T., Hilliard, Massimo A., Bellingham, Mark C. and Noakes, Peter G. (2016). Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis. Scientific Reports, 6 (1) 37968, 37968. doi: 10.1038/srep37968
Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. Journal of Leukocyte Biology, 101 (4), 927-947. doi: 10.1189/jlb.4VMA0716-316R
Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. Human Molecular Genetics, 26 (1), 109-123. doi: 10.1093/hmg/ddw371
Fogarty, Matthew J., Mu, Erica W. H., Noakes, Peter G., Lavidis, Nickolas A. and Bellingham, Mark C. (2016). Marked changes in dendritic structure and spine density precede significant neuronal death in vulnerable cortical pyramidal neuron populations in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica Communications, 4 (77) 77, 1-21. doi: 10.1186/s40478-016-0347-y
Klenowski, Paul M., Shariff, Masroor R., Belmer, Arnauld, Fogarty, Matthew J., Mu, Erica H. W., Bellingham, Mark C. and Bartlett, Selena E. (2016). Prolonged consumption of sucrose in a binge-like manner alters the morphology of medium spiny neurons in the nucleus accumbens shell. Frontiers in Behavioral Neuroscience, 10 (MAR) 54, 54.1-54.10. doi: 10.3389/fnbeh.2016.00054
Patkar, Omkar L., Belmer, Arnauld, Holgate, Joan Y., Tarren, Josephine R., Shariff, Masroor R., Morgan, Michael, Fogarty, Matthew J., Bellingham, Mark C., Bartlett, Selena E. and Klenowski, Paul M. (2016). The antihypertensive drug pindolol attenuates long-term but not short-term binge-like ethanol consumption in mice. Addiction Biology, 22 (3), 679-691. doi: 10.1111/adb.12359
Fogarty, Matthew J., Kanjhan, Refik, Bellingham, Mark C. and Noakes, Peter G. (2016). Glycinergic neurotransmission: A potent regulator of embryonic motor neuron dendritic morphology and synaptic plasticity. Journal of Neuroscience, 36 (1), 80-87. doi: 10.1523/JNEUROSCI.1576-15.2016
Kanjhan, Refik, Noakes, Peter G. and Bellingham, Mark C. (2016). Emerging roles of filopodia and dendritic spines in motoneuron plasticity during development and disease. Neural Plasticity, 2016 3423267, 3423267.1-3423267.31. doi: 10.1155/2016/3423267
Kanjhan, Refik, Fogarty, Matthew J., Noakes, Peter G. and Bellingham, Mark C. (2015). Developmental changes in the morphology of mouse hypoglossal motor neurons. Brain Structure and Function, 221 (7), 1-32. doi: 10.1007/s00429-015-1130-8
Klenowski, Paul M., Fogarty, Matthew J., Belmer, Arnauld, Noakes, Peter G., Bellingham, Mark C. and Bartlett, Selena E. (2015). Structural and functional characterization of dendritic arbors and GABaergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala. Journal of Neurophysiology, 114 (2), 942-957. doi: 10.1152/jn.00824.2014
Fogarty, Matthew J., Noakes, Peter G. and Bellingham, Mark C. (2015). Motor cortex layer V pyramidal neurons exhibit dendritic regression, spine loss, and increased synaptic excitation in the presymptomatic hSOD1G93A mouse model of amyotrophic lateral sclerosis. Journal of Neuroscience, 35 (2), 643-647. doi: 10.1523/JNEUROSCI.3483-14.2015
Fogarty, Matthew J., Yanagawa, Yuchio, Obata, Kunihiko, Bellingham, Mark C. and Noakes, Peter G. (2015). Genetic absence of the vesicular inhibitory amino acid transporter differentially regulates respiratory and locomotor motor neuron development. Brain Structure and Function, 220 (1), 525-540. doi: 10.1007/s00429-013-0673-9
Steyn, F. J., Lee, Kevin, Fogarty, M. J., Veldhuis, J. D., McCombe, P. A,, Bellingham, M. C., Ngo, S. T. and Chen, C (2013). Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology, 154 (12), 4695-4706. doi: 10.1210/en.2013-1570
Fogarty, Matthew J., Hammond, Luke A., Kanjhan, Refik, Bellingham, Mark C. and Noakes, Peter G. (2013). A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs. Frontiers in Neural Circuits, 7 (OCT) 153, 1-18. doi: 10.3389/fncir.2013.00153
Lau, C., Ranasinghe, M. G., Shiels, I., Keates, H., Pasloske, K. and Bellingham, M. C. (2013). Plasma pharmacokinetics of alfaxalone after a single intraperitoneal or intravenous injection of Alfaxan((R)) in rats. Journal of Veterinary Pharmacology and Therapeutics, 36 (5), 516-520. doi: 10.1111/jvp.12055
Bellingham, Mark C. (2013). Pre- and postsynaptic mechanisms underlying inhibition of hypoglossal motor neuron excitability by riluzole. Journal of Neurophysiology, 110 (5), 1047-1061. doi: 10.1152/jn.00587.2012
Fogarty, Matthew J., Smallcombe, Karen L., Yanagawa, Yuchio, Obata, Kunihiko, Bellingham, Mark C. and Noakes, Peter G. (2013). Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development. PLoS One, 8 (2) e56257, e56257. doi: 10.1371/journal.pone.0056257
Ngo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028
Ireland, Matthew F., Funk, Gregory D. and Bellingham, Mark C. (2012). Muscarinic acetylcholine receptors enhance neonatal mouse hypoglossal motoneuron excitability in vitro. Journal of Applied Physiology, 113 (7), 1024-1039. doi: 10.1152/japplphysiol.00699.2011
Steyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171
Kanjhan, Refik and Bellingham, Mark C. (2011). Penetratin peptide potentiates endogenous calcium-activated chloride currents in Xenopus oocytes. Journal of Membrane Biology, 241 (1), 21-29. doi: 10.1007/s00232-011-9359-5
Bellingham, Mark C. (2011). A review of the neural mechanisms of action and clinical efficiency of Riluzole in treating Amyotrophic Lateral Sclerosis: What have we learned in the last decade?. CNS Neuroscience and Therapeutics, 17 (1), 4-31. doi: 10.1111/j.1755-5949.2009.00116.x
Kanjhan, Refik, Pow, David V., Noakes, Peter G. and Bellingham, Mark C. (2010). The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges. Journal of Molecular Histology, 41 (6), 315-323. doi: 10.1007/s10735-010-9293-3
van Zundert, B., Peuscher, M. H., Hynynen, M., Chen, A., Neve, R. L., Brown, R. H., Constantine-Paton, M. and Bellingham, M. C. (2008). Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis. Journal of Neuroscience, 28 (43), 10864-10874. doi: 10.1523/JNEUROSCI.1340-08.2008
Noakes, P. G., Smallcombe, K., Arata, A., Obata, A., Davies, J. and Bellingham, M. C. (2007). GABA-deficient mice produce regional alterations in motoneuron survival during neural development. The Society for Neuroscience Abstracts, 27 (33).
Mills, P.C., Woodall, P.F., Bellingham, M.C., Noad, M.J. and Lloyd, S. (2007). Using group learning to promote integration and cooperative learning between Asian and Australian second-year Veterinary Science students. Journal of Veterinary Medical Education, 34 (3), 350-355. doi: 10.3138/jvme.34.3.350
Fuller, Paula I., Reddrop, Courtney, Rodger, Jennifer, Bellingham, Mark C. and Phillips, Jacqueline K. (2006). Differential expression of the NMDA NR2B receptor subunit in motoneuron populations susceptible and resistant to amyotrophic lateral sclerosis. Neuroscience Letters, 399 (1-2), 157-161. doi: 10.1016/j.neulet.2006.01.051
Noakes, P. G., Smallcombe, K. L., Kanjhan, R., Arata, A., Banks, G., Obata, K., Betz, H. and Bellingham, M. C. (2006). Developmental regulation of the neuromotor circuit: peripheral and central synaptic influences in motoneuron numbers and innervation of muscle. Proceedings of the Australian Society for Biochemistry and Molecular Biology, 38, SYM-57-03-SYM-57-03.
Kanjhan, Refik, Hryciw, Deanne H., Yun, C. Chris, Bellingham, Mark C. and Poronnik, Philip (2006). Postnatal developmental expression of the PDZ scaffolds Na+-H+ exchanger regulatory factors 1 and 2 in the rat cochlea. Cell And Tissue Research, 323 (1), 53-70. doi: 10.1007/s00441-005-0051-x
Kanjhan, R., Coulson, E. J., Adams, D. J. and Bellingham, M. C. (2005). Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner. Journal of Pharmacology And Experimental Therapeutics, 314 (3), 1353-1361. doi: 10.1124/jpet.105.085928
Banks, Glen B., Kanjhan, Refik, Wiese, Stefan, Kneussel, Matthias, Wong, Loke M., O'Sullivan, Gregory, Sendtner, Michael, Bellingham, Mark C., Betz, Heinrich and Noakes, Peter G. (2005). Erratum: Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. Journal of Neuroscience, 25 (11), 3018-3021.
Banks, GB, Kanjhan, R, Wiese, S, Kneussel, M, Wong, LM, O'Sullivan, G, Sendtner, M, Bellingham, MC, Betz, H and Noakes, PG (2005). Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. Journal of Neuroscience, 25 (5), 1249-1259. doi: 10.1523/JNEUROSCI.1786-04.2005
Kanjhan, Refik, Anselme, Amy, Noakes, Peter and Bellingham, Mark (2004). Postnatal changes in TASK-1 and TREK-1 expression in rat brain stem and cerebellum. Neuroreport, 15 (8), 1321-1324. doi: 10.1097/01.wnr.0000127462.15985.dc
Kanjhan, Refik, Balke, Caroline, Housley, Gary, Bellingham, Mark and Noakes, Peter (2004). Developmental expression of two-pore domain K+ channels, TASK-1 and TREK-1, in the rat cochlea. Neuroreport, 15 (3), 437-441. doi: 10.1097/01.wnr.0000114978.66165.39
Ireland, M. F., Noakes, P. G. and Bellingham, M. C. (2004). P2x(7)-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms. Neuroscience, 128 (2), 269-280. doi: 10.1016/j.neuroscience.2004.06.014
Knight, D, Bellingham, MC and Lavidis, NA (2004). The effect of N-ethylmaleimide on transmitter release from the skeletal neuromuscular junction of Bufo marinus. Synapse, 53 (3), 151-158. doi: 10.1002/syn.20044
Bellingham, MC and Ireland, MF (2002). Contribution of cholinergic systems to state-dependent modulation of respiratory control. Respiratory Physiology & Neurobiology, 131 (1-2), 135-144. doi: 10.1016/S1569-9048(02)00043-5
Bellingham, M. C. (2000). Australian Neuroscience Society--20th Annual Meeting. 30 January-2 February 2000, Melbourne, Australia. IDrugs : the investigational drugs journal, 3 (5), 490-2.
Bellingham, M. C. (2000). Australian Neuroscience Society - 20th Annual Meeting. IDrugs, 3 (5), 490-492.
Bellingham, MC (1999). Synaptic inhibition of cat phrenic motoneurons by internal intercostal nerve stimulation. Journal of Neurophysiology, 82 (3), 1224-1232.
Bellingham, M C (1999). Synaptic inhibition of cat phrenic motoneurons by internal intercostal nerve stimulation. Journal of neurophysiology, 82 (3), 1224-32. doi: 10.1152/jn.1999.82.3.1224
Bellingham, MC and Walmsley, B (1999). A novel presynaptic inhibitory mechanism underlies paired pulse depression at a fast central synapse. Neuron, 23 (1), 159-170. doi: 10.1016/S0896-6273(00)80762-X
Bellingham, MC (1998). Driving respiration: The respiratory central pattern generator. Clinical and Experimental Pharmacology and Physiology, 25 (10), 847-856. doi: 10.1111/j.1440-1681.1998.tb02166.x
Bellingham, MC, Lim, R and Walmsley, B (1998). Developmental changes in EPSC quantal size and quantal content at a central glutamatergic synapse in rat. Journal of Physiology, 511 (3), 861-869. doi: 10.1111/j.1469-7793.1998.861bg.x
Baraban, SC, Bellingham, MC, Berger, AJ and Schwartzkroin, PA (1997). Osmolarity modulates K+ channel function on rat hippocampal interneurons but not CA1 pyramidal neurons. Journal of Physiology-London, 498 (3), 679-689. doi: 10.1113/jphysiol.1997.sp021892
Bellingham, MC and Berger, AJ (1996). Presynaptic depression of excitatory synaptic inputs to rat hypoglossal motoneurons by muscarinic M2 receptors. Journal of Neurophysiology, 76 (6), 3758-3770. doi: 10.1152/jn.1996.76.6.3758
Singer, JH, Bellingham, MC and Berger, AJ (1996). Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin. Journal of Neurophysiology, 76 (2), 799-807. doi: 10.1152/jn.1996.76.2.799
Schmidt, C, Bellingham, MC and Richter, DW (1995). Adenosinergic Modulation of Respiratory Neurons and Hypoxic Responses in the Anesthetized Cat. Journal of Physiology-London, 483 (3), 769-781. doi: 10.1113/jphysiol.1995.sp020621
Ballanyi, K, Muckenhoff, K, Bellingham, MC, Okada, Y, Scheid, P and Richter, DW (1994). Activity-Related Ph Changes in Respiratory Neurons and Glial-Cells of Cats. Neuroreport, 6 (1), 33-36. doi: 10.1097/00001756-199412300-00010
Bellingham, MC and Berger, AJ (1994). Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro. Neuroscience Letters, 177 (1-2), 143-146. doi: 10.1016/0304-3940(94)90065-5
Dick, TE, Bellingham, MC and Richter, DW (1994). Pontine respiratory neurons in anesthetized cats. Brain Research, 636 (2), 259-269. doi: 10.1016/0006-8993(94)91025-1
Bayliss, DA, Viana, F, Bellingham, MC and Berger, AJ (1994). Characteristics and Postnatal-Development of a Hyperpolarization-Activated Inward Current in Rat Hypoglossal Motoneurons In-Vitro. Journal of Neurophysiology, 71 (1), 119-128. doi: 10.1152/jn.1994.71.1.119
Ballanyi, K., Mückenhoff, K., Bellingham, M. C., Okada, Y., Scheid, P. and Rioter, D. W. (1994). pH changes in respiratory neurons: A phenomenon at the search of a function. NeuroReport, 6 (1). doi: 10.1097/00001756-199412300-00001
Klages, S, Bellingham, MC and Richter, DW (1993). Late Expiratory Inhibition of Stage-2 Expiratory Neurons in the Cat - a Correlate of Expiratory Termination. Journal of Neurophysiology, 70 (4), 1307-1315. doi: 10.1152/jn.1993.70.4.1307
Mückenhoff, K., Schreiber, S., Kawai, A., Scheid, P., Ballanyi, K., Bellingham, M. and Richter, D. W. (1993). Meßsystem zur Bestimmung schneller intrazellulärer pH-Signale. Biomedizinische Technik, 38 (s1), 307-308. doi: 10.1515/bmte.1993.38.s1.307
Bellingham, MC and Lipski, J (1992). Morphology and electrophysiology of superior laryngeal nerve afferents and postsynaptic neurons in the medulla oblongata of the cat. Neuroscience, 48 (1), 205-216. doi: 10.1016/0306-4522(92)90349-7
Richter, DW, Bischoff, A, Anders, K, Bellingham, M and Windhorst, U (1991). Response of the Medullary Respiratory Network of the Cat to Hypoxia. Journal of Physiology-London, 443 (1), 231-256. doi: 10.1113/jphysiol.1991.sp018832
Bellingham, MC and Lipski, J (1990). Respiratory interneurons in the C5 segment of the spinal cord of the cat. Brain Research, 533 (1), 141-146. doi: 10.1016/0006-8993(90)91807-S
Bellingham, MC, Lipski, J and Voss, MD (1989). Synaptic inhibition of phrenic motoneurons evoked by stimulation of the superior laryngeal nerve. Brain Research, 486 (2), 391-395. doi: 10.1016/0006-8993(89)90530-1
Lipski, J, Bellingham, MC, West, MJ and Pilowsky, P (1988). Limitations of the Technique of Pressure Microinjection of Excitatory Amino-Acids for Evoking Responses From Localized Regions of the Cns. Journal of Neuroscience Methods, 26 (2), 169-179. doi: 10.1016/0165-0270(88)90166-5
Conference Papers
Kotapati, Charan , Bellingham, Mark C. and Cardoso, Fernanda C. (2022). Idiosyncratic treatment of motor neuron disease: selective inhibition of voltage-gated sodium channels using spider venom peptide (ProTX-III) to treat motor neuron disease. Pathogens and Natural Toxins e-Conference section Diagnostics and Therapeutics From Natural Toxins, Brisbane, Australia, 1 July - 31 August 2022.
Pradhan, Jonu, Noakes, Peter G. and Bellingham, Mark C. (2018). IVT-14 Layer V pyramidal neurons showing synaptic hyper-excitability has altered TrkB receptor signaling in SOD1G3A mouse model of ALS. 29th International Symposium on ALS/MND, Glasgow, Scotland, 7-9 December 2018. Abingdon, Oxfordshire, United Kingdom: Taylor & Francis. doi: 10.1080/21678421.2018.1510569
Cardoso, Fernanda C., Bellingham, Mark C., King, Glenn F. and Lewis, Richard J. (2017). Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017.
Thakre, P. and Bellingham, M. (2017). Alfaxalone alters inhibitory but not excitatory synaptic transmission or action potential firing in rat hypoglossal motor neurons. ISN-ESN Meeting, Paris France, 20-24 August 2017. Chichester, West Sussex United Kingdom: Wiley.
Quek, H., Luff, J., Cheung, K., Kozlov, S., Gatei, M., Lee, C. S., Bellingham, M., Noakes, P., Lim, Y. C., Barnett, N., Dingwall, S., Wolvetang, E., Mashimo, T., Roberts, T. and Lavin, M. (2016). Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200
Ajayi, I., Mills, P., Bellingham, M., Silburn, P. and Subramanian, H. (2015). Hippocampal influence on the respiratory and cardiovascular system. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, Aug 23-27, 2015. HOBOKEN: WILEY-BLACKWELL.
Qian, L., Marks, N., Sharma, A., Bellingham, M. and Coulson, E. (2015). Cholinergic dysfunction of mesopontine tegmentum is involved in the development of Alzheimer's disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, QLD, Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13189
Klenowski, P. M., Holgate, J., Bellingham, M., Molenaar, P. and Bartlett, S. (2013). The role of beta1 adrenoceptors in the development of alcohol dependence. Neuroscience 2013: 43rd Annual Meeting of the Society for Neuroscience, San Diego, CA, USA, 9-13 November, 2013.
Fogarty, M. J., Hammond, L. A., Kanjhan, R., Bellingham, M. C. and Noakes, P. G. (2013). A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment. Neuroscience 2013: 43rd Annual Meeting of the Society for Neuroscience, San Diago, CA, United States, 9-13 November, 2012.
Klenowski, Paul, Holgate, Joan, Bellingham, Mark, Molenaar, Peter and Bartlett, Selena E. (2013). Investigating the Contribution of Beta1 Adrenoceptors in the Development of Alcohol Dependence. The Australasian Professional Society on Alcohol and other Drugs Conference, Brisbane, Australia, 24 -27 November 2013. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing Ltd.. doi: 10.1111/dar.12077
Butt, E. A., Bellingham, M. C. and Lavidis, N. A. (2012). Plant derived chemicals alleviate the effects of chronic stress on neuronal morphology and synaptic plasticity of hippocampal neurons. Neuroscience 2012: 42nd Annual Meeting of the Society for Neuroscience, New Orleans, LA, USA, 13-17 October, 2012. Washington, DC, United States: Society for Neuroscience.
McCombe, Pamela, Ngo, Shuyan, Bellingham, Mark, Pettitt, Anthony and Henderson, Robert (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd Annual Meeting of the American-Academy-of-Neurology, Honolulu, HI, U.S.A., APR 09-16, 2011. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins.
Steyn, F.J., Ngo, S.T., Buckley, A.J., Leong, J.W., Veldhuis, J.D., McCombe, P.A., Chen, C. and Bellingham, M.C. (2011). Pulsatile Growth Hormone Secretion in the SOD1G93A Mouse Model of ALS. Endocrine Society of Australia Annual Scientific Meeting, Perth Convention and Exhibition Centre, Perth, Western Australia, 28-31 August.
Ngo, S. T., Steyn, F. J., Buckley, A. J., Leong, J. W., Veldhuis, J. D., Chen, C., McCombe, P. A. and Bellingham, M. C. (2011). Pulsatile growth hormone secretion in the SOD1G93A mouse model of ALS resembles growth hormone deficiency in ALS patients. 22nd International ALS/MND Symposium, Sydney, Australia, 30 November - 2 December 2011.
Ngo, S. T., Bellingham, M. C., Pettitt, A. N., Ridall, P. G., Henderson, R. D. and McCombe, P. A. (2011). Comparison of motor unit number estimation by Bayesian statistical MUNE with histological counting of motor unit numbers. 22nd International ALS/MND Symposium, Sydney, Australia, 30 November - 2 December 2011.
Ngo, S. T., Baumann, F., Pettitt, A. N., Ridall, P. G., Henderson, R. D., McCombe, P. A. and Bellingham, M. C. (2011). Estimation of Motor Unit Loss in Amyotrophic Lateral Sclerosis (ALS). Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand, 31 January -3 February 2011.
McCombe, P., Ngo, S., Bellingham, M., Pettitt, A. and Henderson, R. (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd AAN Annual Meeting, Honolulu, HI, United States, 9-16 April 2011.
Ngo, S.T., Bellingham, M.C., Baumann, F., Pettitt, A.N., Ridall, P.G., Henderson, R.D. and McCombe, P.A. (2010). Bayesian Motor Unit Number Estimation in the SOD1G93A mouse. Forum of European Neuroscience, AMSTERDAM NETHERLANDS, 3/7/2010-7/7/2010.
Noakes, Peter G., Smallcombe, Karen, Davis, Jonathan and Bellingham, Mark C. (2006). A lack of GABA produces regional alterations in motoneuron activity, motoneuron survival and innervation of mice during neural development. ComBio 2006, Brisbane, Australia, 24-28 September, 2006. Online:
Arata, A., Obata, K., Davies, J., Bellingham, M. and Noakes, P. G. (2006). Decrease in spontaneous activity and cell death of the brachial motoneurons in GAD67-deficient mouse embryo. 29th Annual Meeting of the Japan Neuroscience Society, Kyoto, Japan, 19-21 July 2006. Clare: Elsevier Ireland Ltd. doi: 10.1016/j.neures.2006.04.004
Kanjhan, R., Pow, D.V., Birt, J.B., Noakes, P.G. and Bellingham, M.C. (2004). A new marker for the meningeo-glial network: a two pore domain K channel TASK1. Australian Neuroscience Society - 24th Annual Meeting, Melbourne, Australia, 27-30 January, 2004. Amsterdam: Elsevier/North-Holland.
Wong, L. M., Kanjhan, R., Bellingham, M. C. and Noakes, P. G. (2004). Hypoglossal and spinal motor neural activity in gephyrin-deficient versus wild-type mice. Australian Neuroscience Society, 24th Annual Meeeting, Melbourne, Australia, 27-30 January, 2004. Australia: Australian Neuroscience Society.
Noakes, Peter G., Kanjhan, Refik, Balke, Caroline L., Nguyen, Thanh T., Housley, G. and Bellingham, Mark C. (2004). Expression of two pore domain K channels TASK1 and TREK1, in the rat cochlea: implications for Tinnitus. Australian Neuroscience Society Meeting 24th Annual Meeting, Melbourne, 27-30 January, 2004. Melbourne: Australian Neuroscience Society.
Bellingham, M. C., Kanjhan, R., Huang, L. C., Housley, G. D., Lipski, J., Funk, G. D. and Noakes, P. G. (2004). Locaization of TASK1 and TREK1 Two Pore Domain K Channels and P2Y2 and P2Y4 Receptors in Rat Hypoglossal Motoneurons. 24th Annual Meeting of the Australian Neuroscience Society, Melbourne, Australia, 27-30 January, 2004. Melbourne: Australian Neuroscience Inc.
Birt, J., Ireland, M., Knight, D., Noakes, P. G. and Bellingham, M. (2003). P2X7 receptors enhance excitatory central synaptic transmission. Australian Neuroscience Society 23rd Annual Meeting, Adelaide, 28-31 January, 2003. Australia: Australian Neuroscience Sociey Inc..
Noakes, P. G., Koshi, K., Frugier, T., White, M., Bellingham, M. and Mclennan I. (2003). The Use of Cell Type Specific Knockout Mice to Study the Roles of Synaptic Signalling Molecules in the Nervous System. Australian Neurological Society Annual Conference, Adelaide, 2003.
Banks, G., Bellingham, M., Kneussel, M., Sullivan, M., Betz, H. and Noakes, P. (2003). Motoneuron survival in the absence of GABA and glycine neurotransmission during embryonic development. Australian Neuroscience Society 23rd Annual Meeting, Adelaide, 28-31 January, 2003. Australia: Australian Neuroscience Sociey.
Knight, D., Ireland, M. F., Bellingham, M. C. and Noakes, P. G. (2002). Role of P2X7 receptors in transmitter release in mice. Society for Neuroscience Annual Meeting 2002, Orlando, Florida, 2-7 November, 2002. Washington , DC: Society for Neuroscience.
Bellingham, M. C. (2001). Developmental changes in short-term synaptic plasticity at a central auditory synapse. 21st Meeting of the Australian Neuroscience Society, Brisbane, 28-31 January 2001. Sydney: ANS.
Noakes, P. G., Banks, G., Choy, P. T., Lavidis, N. A. and Bellingham, M. C. (2001). Motoneuron cell death, branching and muscle activity in agrin-deficient mice. 31st Annual Meeting of the Society for Neuroscience, San Diego, 10-15 November 2001. USA: Society for Neuroscience.
Bellingham, M. C. (2001). Rapid developmental regulation of presynaptic factors governing synaptic transmission and plasticity at central synapses. 14th Biennial Meeting of the Int. Society for Dev. Neuroscience, Sydney, 31/1 - 4/2 2002. United Kingdom: Pergamon.
Bellingham, M. C., Funk, G. D., Ireland, M., Miles, G. B., Robinson, D. M. and Selvaratnam, S. R. (2001). Contribution of cholinergic systems to state-dependent modulation of respiratory networks. Neural Control of Breathing Satellite Meeting, Rotorua, New Zealand, 1-4 September, 2001. London, United Kingdom: BioMed Central. doi: 10.1186/rr112
Knight, D., Bellingham, M. C. and Lavidis, N. A. (2000). Effect of N-Ethylmaleimide on transmitter release at the skeletal neuromuscular junction of Bufo Marinus. Society for Neuroscience, New Orleans, LA, USA, 4-9 November 2000. USA: Society for Neuroscience.
Bellingham, Mark C. and Funk, Greg D. (2000). Cholinergic modulation of respiratory brain-stem neurons and its function in sleep-wake state determination. Australian Neuroscience Society Symposium on Nervous Control of Breathing, Hobart, Australia, January/February 1999. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1046/j.1440-1681.2000.03192.x
Richter, DW, Bellingham, MC and Schmidt, C (1992). Maintenance of the Respiratory Rhythm During Normoxia and Hypoxia. 5Th Oxford Conf On Control of Breathing and its Modelling Perspective, Fuji Japan, Sep 17-19, 1991. NEW YORK: PLENUM PRESS DIV PLENUM PUBLISHING CORP.
Data Collection
Coulson, Elizabeth, Qian, Lei, Bellingham, Mark, Georgeson, Thomas, Garner, Nicholas and Dean, Matthew (2022). Cholinergic basal forebrain degeneration due to sleep-disordered breathing project source data. The University of Queensland. (Dataset) doi: 10.48610/81462a6