Emeritus Professor Chen Chen

Huang, Lili, Huang, Zhengxiang, Chen, Yang and Chen, Chen (2020). Neuroendocrine and metabolic regulation of plasma growth hormone secretory profiles. Neurosecretion: secretory mechanisms. (pp. 195-218) edited by Jose R. Lemos, Govindan Dayanithi. Cham, Switzerland: Springer Nature Switzerland. doi: 10.1007/978-3-030-22989-4_10

Steyn, Frederik J. and Chen, Chen (2013). Adiponectin. Handbook of biologically active peptides. (pp. 983-989) edited by Abba J. Kastin. Amsterdam, Netherlands: Academic Press/Elsevier. doi: 10.1016/B978-0-12-385095-9.00130-5

Fung, Jenny N.T. and Chen, Chen (2012). Endometrial cancer: diagnosis, treatment and prevention. Horizons in cancer research. Volume 49. (pp. 1-32) edited by Hiroto S. Watanabe. Hauppauge, NY, USA: Nova Publishers.

Zhao, Yufeng and Chen, Chen (2011). Adipsin as an adipokine. Adipokines. (pp. 20-28) edited by Victor R. Preedy and Ross J. Hunter. Enfield, NH, United States: Science Publishers.

Chen, Chen (2002). Cell biology and membrane function. Textbook of Medical Physiology. (pp. 7-26) China: People's Health Press.

Chen, Chen and Clarke, Iain J. (1999). Intracellular GHRP signalling. Growth hormone secretagogues: basic findings and clinical implications. (pp. 53-63) edited by E. Ghigo, M. Boghen, F. F. Casanueva and C. Dieguez. Amsterdam, The Netherlands: Elsevier.

Chen, Chen (1998). Introduction of a new laboratory technique to investigate roles of intracellular signal pathways in the regulation of cell membrane ion channels. Proceedings of Chinese Academy of Medical Sciences. (pp. 1-26) Beijing, China: Peking Union Medical College and Chinese Academy of Medical Sciences.

Lledo, Pierre-Marie, Kukstas, Lucy A., Chen, Chen, Vincent, Jean-Didier and Israel, Jean-Marc (1990). Ionic currents in the regulation of stimulus-secretion coupling in normal and tumoral adenohypophyseal cells. Recent advances in basic and clinical neuroendocrinology. (pp. 65-74) edited by F. F. Casanueva and C. Dieguez. Amsterdam, The Netherlands: Elsevier Science Publishers.

Geng, Shan, Yang, Shan, Tang, Xuejiao, Xue, Shiyao, Li, Ke, Liu, Dongfang, Chen, Chen, Zhu, Zhiming, Zheng, Hongting, Wang, Yuanqiang, Yang, Gangyi, Li, Ling and Yang, Mengliu (2024). Intestinal NUCB2/nesfatin-1 regulates hepatic glucose production via the MC4R-cAMP-GLP-1 pathway. The EMBO Journal, 1-21. doi: 10.1038/s44318-024-00300-4

Bo, Surina, Dan, Mu, Li, Wei and Chen, Chen (2024). The regulatory mechanism of natural polysaccharides in type 2 diabetes mellitus treatment. Drug Discovery Today, 29 (11) 104182, 104182. doi: 10.1016/j.drudis.2024.104182

Hu, Huiming, Wang, Shuwen and Chen, Chen (2024). Pathophysiological role and potential drug target of NLRP3 inflammasome in the metabolic disorders. Cellular Signalling, 122 111320, 111320. doi: 10.1016/j.cellsig.2024.111320

Wang, Weihao, Wei, Ran, Xiao, Pei, Jiang, Xun, Chen, Zihao, Huang, Jinghe, Ma, Yanhua, Gao, Danni, Shao, Jian, Yu, Jun, Zhou, Kaixin, Chen, Chen, Li, Ying, Pan, Ying, Pan, Qi, Jia, Tong and Guo, Lixin (2024). Deep Contrast Clustering Analysis to Distinguish Diabetic Complications in Elderly Chinese Patients. Diabetes/metabolism research and reviews, 40 (7) ARTN e70000. doi: 10.1002/dmrr.70000

Zhao, Meijun, Liu, Chang, Liu, Zhenye, Zuo, Yuanyuan, Chen, Chen, Shi, Shuai, Shi, Xinlin, Xie, Yining, Yang, Huiying and Chen, Yutong (2024). Myocardium-targeted liposomal delivery of the antioxidant peptide 8P against doxorubicin-induced myocardial injury. International Journal of Pharmaceutics, 663 124569, 124569. doi: 10.1016/j.ijpharm.2024.124569

Liu, Kun, Li, Yuemeng, Yin, Fanxing, Wu, Xiaoyu, Zhang, Xiaoxu, Jiang, Deying, Wang, Jian, Zhang, Zhaoxuan, Wang, Ruihua, Chen, Chen and Han, Yanshuo (2024). Elucidating thoracic aortic dissection pathogenesis: The interplay of m1A-related gene expressions and miR-16-5p/YTHDC1 Axis in NLRP3-dependent pyroptosis. International Journal of Biological Macromolecules, 274 (Part 2) 133293, 133293. doi: 10.1016/j.ijbiomac.2024.133293

Liu, Fang, Zhang, Ruiyuan, Shen, Caijia, Fu, Xinyi, Song, Yao, Lei, Yichen, Pang, Huiwen, Liu, Yang, Chen, Chen and Li, Jie (2024). Mechanism of Houpo Sanwu Decoction on preventing and treating acute gastric ulcer in rats based on stomach-brain correlation 基于胃脑相关探讨厚朴三物汤防治急性胃溃疡大鼠的作用机制. Chinese Traditional and Herbal Drugs, 55 (16), 5525-5540. doi: 10.7501/j.issn.0253-2670.2024.16.015

Wang, Weihao, Qiao, Jingtao, Zhang, Lina, Zhang, Jie, Luo, Jingyi, Chen, Chen, Wang, Xiaoxia, Jia, Peng, Zhang, Jia, Pan, Qi and Guo, Lixin (2024). Prevalence of very high cardiovascular disease risk in patients with type 2 diabetes mellitus: A population‐based cross‐sectional screening study. Diabetes, Obesity and Metabolism, 26 (10), 4251-4260. doi: 10.1111/dom.15763

Wu, Wei, Yi, Lisha, Zhang, Kai, Chen, Zipei, Shi, Caiping, Chen, Chen, Cai, Yilu, Hu, Lidan and Chen, Xiangjun (2024). Health-related quality of life measurements in children and adolescents with refractive errors: a scoping review. Advances in Ophthalmology Practice and Research, 4 (2), 84-94. doi: 10.1016/j.aopr.2024.03.001

Qiu, Sheng, Wu, Qinan, Wang, Hao, Liu, Dongfang, Chen, Chen, Zhu, Zhiming, Zheng, Hongting, Yang, Gangyi, Li, Ling and Yang, Mengliu (2024). AZGP1 in POMC neurons modulates energy homeostasis and metabolism through leptin-mediated STAT3 phosphorylation. Nature Communications, 15 (1) 3377, 1-18. doi: 10.1038/s41467-024-47684-9

Shen, Jiayi, Jiang, Lai, Wang, Kan, Wang, Anqi, Chen, Fei, Newcombe, Paul J., Haiman, Christopher A. and Conti, David V. (2024). Hierarchical joint analysis of marginal summary statistics-Part I: Multipopulation fine mapping and credible set construction. Genetic Epidemiology, 48 (6), 241-257. doi: 10.1002/gepi.22562

Bai, Xufeng, Wang, Shuwen, Shu, Limei, Cao, Qingyu, Hu, Huiming, Zhu, Yanchen and Chen, Chen (2024). Hawthorn leaf flavonoids alleviate the deterioration of atherosclerosis by inhibiting SCAP-SREBP2-LDLR pathway through sPLA2-ⅡA signaling in macrophages in mice. Journal of Ethnopharmacology, 327 118006, 118006. doi: 10.1016/j.jep.2024.118006

Yang, Jianmei and Chen, Chen (2024). Hormonal changes in PCOS. Journal of Endocrinology, 261 (1) 230342. doi: 10.1530/joe-23-0342

Yamada, Kohei, Menon, Jaivardhan A., Kim, Yaunghyun, Cheng, Changde, Chen, Wenan, Shih, Jenny A., Villasenor-Altamirano, Ana B., Chen, Xiang, Tamura, Tomoyoshi, Merriam, Louis T., Kim, Edy Y. and Weissman, Alexandra J. (2024). Protocol for immunophenotyping out-of-hospital cardiac arrest patients. Star Protocols, 5 (1) 102874, 1-24. doi: 10.1016/j.xpro.2024.102874

Geng, Nan, Dong, Siyuan, Xie, Pengpeng, Zhang, Yi, Shi, Rong, Chen, Chen, Xu, Zhao and Chen, Qun (2024). Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells. Reproductive Toxicology, 125 108556, 108556. doi: 10.1016/j.reprotox.2024.108556

Zhang, Wenyi, Yao, Jing, Chen, Chen, Wang, Jianming and Zhou, Aiyi (2024). Fetuin-B overexpression promotes inflammation in diabetic retinopathy through activating microglia and the NF-κB signaling pathway. Current Eye Research, 49 (2), 168-179. doi: 10.1080/02713683.2023.2276683

Pang, Huiwen, Wu, Youzhi, Chen, Yang, Chen, Chen, Nie, Xuqiang, Li, Peng, Huang, Guojun, Xu, Zhi Ping and Han, Felicity Y. (2024). Development of polysaccharide-coated layered double hydroxide nanocomposites for enhanced oral insulin delivery. Drug Delivery and Translational Research, 14 (9), 2345-2355. doi: 10.1007/s13346-023-01504-7

Xue, Yanan, Wei, Yue, Cao, Lan, Shi, Min, Sheng, Junqing, Xiao, Qin, Cheng, Ziwen, Luo, Tao, Jiao, Quanhui, Wu, Ailan, Chen, Chen, Zhong, Lingyun and Zhang, Changhua (2024). Protective effects of scutellaria-coptis herb couple against non-alcoholic steatohepatitis via activating NRF2 and FXR pathways in vivo and in vitro. Journal of Ethnopharmacology, 318 (Pt A) 116933, 1-18. doi: 10.1016/j.jep.2023.116933

Liu, Chang, Ding, Xuying, Xie, Yining, Chen, Chen, Zhao, Meijun, Duan, Yanming, Yuan, Guojing and Ren, Junxi (2024). Isolation and purification of Eleutherococcus sessiliflorus (Rupr. & Maxim.) S. Y. Hu peptides and study of their antioxidant effects and mechanisms. Frontiers in Pharmacology, 15 1353871. doi: 10.3389/fphar.2024.1353871

Li, Jiaxi, Li, Mei, Ke, Hao, Han, Yang, Huang, Yanhong, Zhou, Yan, Luo, Ziqiang, Chen, Chen and Feng, Dandan (2024). LEAP2 ameliorates high fat diet-impaired glucose tolerance and enhances glucose-stimulated insulin secretion from β cells through PPARγ signal pathway. Chinese Medical Journal, 137 (18), 2266-2268. doi: 10.1097/CM9.0000000000003215

Song, Yueqin, Chen, Chen and Li, Wei (2024). Ginsenoside Rb1 in cardiovascular and cerebrovascular diseases: A review of therapeutic potentials and molecular mechanisms. Chinese Herbal Medicines, 16 (4), 489-504. doi: 10.1016/j.chmed.2024.09.006

He, Yirui, Zhang, Cheng, Wu, Shaobo, Li, Ke, Zhang, Siliang, Tian, Mingyuan, Chen, Chen, Liu, Dongfang, Yang, Gangyi, Li, Ling and Yang, Mengliu (2024). Central NUCB2/nesfatin-1 signaling ameliorates liver steatosis through suppression of endoplasmic reticulum stress in the hypothalamus: Central nesfatin-1 ameliorates hepatosteatosis. Metabolism: Clinical and Experimental 156046, 156046. doi: 10.1016/j.metabol.2024.156046

Yang, Shan, Li, Yang, Tian, Mingyuan, Deng, Wuquan, Liu, Dongfang, Chen, Chen, Zhu, Zhiming, Zheng, Hongting, Yang, Gangyi, Li, Ling and Yang, Mengliu (2024). Hypothalamic P62 (SQSTM1) regulates energy balance by modulating leptin signaling. Theranostics , 14 (17), 6605-6624. doi: 10.7150/thno.96480

Liao, Qingwu, Li, Fang, Xue, Mingming, Chen, Wenan, Tao, Zhengang, Song, Yuejiao and Yuan, Ying (2023). Polydatin alleviates sepsis-induced acute lung injury via downregulation of Spi-B. Biomedical Reports, 19 (6) ARTN 102. doi: 10.3892/br.2023.1684

Li, Lin, Zhang, Ruiyuan, Hu, Yichen, Deng, Hongdan, Pei, Xu, Liu, Fang and Chen, Chen (2023). Impact of Oat (Avena sativa L.) on metabolic syndrome and potential physiological mechanisms of action: a current review. Journal of Agricultural and Food Chemistry, 71 (41), 14838-14852. doi: 10.1021/acs.jafc.3c02304

Du, Ming-Fei, Zhang, Xi, Hu, Gui-Lin, Mu, Jian-Jun, Chu, Chao, Liao, Yue-Yuan, Chen, Chen, Wang, Dan, Ma, Qiong, Yan, Yu, Jia, Hao, Wang, Ke-Ke, Sun, Yue, Niu, Ze-Jiaxin, Man, Zi-Yue, Wang, Lan, Zhang, Xiao-Yu, Luo, Wen-Jing, Gao, Wei-Hua, Li, Hao, Wu, Guan-Ji, Gao, Ke, Zhang, Jie and Wang, Yang (2023). Associations of lipid accumulation product, visceral adiposity index, and triglyceride-glucose index with subclinical organ damage in healthy Chinese adults. Frontiers in Endocrinology, 14 1164592. doi: 10.3389/fendo.2023.1164592

Xu, Yangting, Chen, Chen, Ji, Ming, Xiang, Yang, Han, Yang, Feng, Dandan and Luo, Ziqiang (2023). An online flipped classroom approach improves the physiology score and subsequent course scores of the top-performing students. Advances in Physiology Education, 47 (3), 538-547. doi: 10.1152/advan.00060.2022

Zhang, Wanlong, Zhang, Changhua, Cao, Lan, Liang, Fang, Xie, Weihua, Tao, Liang, Chen, Chen, Yang, Ming and Zhong, Lingyun (2023). Application of digital-intelligence technology in the processing of Chinese materia medica. Frontiers in Pharmacology, 14 1208055, 1-12. doi: 10.3389/fphar.2023.1208055

Li, Hongzhuo, Gu, Wenyi, Jeffery, Penny and Chen, Chen (2023). 17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells. Clinical and Translational Medicine, 13 (7) e1330, e1330. doi: 10.1002/ctm2.1330

Yang, Jianmei, Wang, Enli, Chen, Wenbin, Xu, Baihui, Chen, Chen, Zhang, Guimin and Yao, Jingchun (2023). TMT-based proteomics analysis of the intervention effect of orlistat on polycystic ovary syndrome rats induced by letrozole combined with a high-fat diet. ACS Omega, 8 (28), 24831-24840. doi: 10.1021/acsomega.3c00578

Zhang, Jing-Tian, Xie, Li-Ya, Shen, Qiong, Liu, Wei, Li, Ming-Han, Hu, Rui-Yi, Hu, Jun-Nan, Wang, Zi, Chen, Chen and Li, Wei (2023). Platycodin D stimulates AMPK activity to inhibit the neurodegeneration caused by reactive oxygen species-induced inflammation and apoptosis. Journal of Ethnopharmacology, 308 116294, 1-13. doi: 10.1016/j.jep.2023.116294

Chen, Chen and Smith, Maree T. (2023). The NLRP3 inflammasome: role in the pathobiology of chronic pain. Inflammopharmacology, 31 (4), 1589-1603. doi: 10.1007/s10787-023-01235-8

Zhang, Yue, Xian, He, Strounina, Ekaterina, Gunther, Kimberley S., Sweet, Matthew J., Chen, Chen, Yu, Chengzhong and Wang, Yue (2023). Mesoporous Organosilica Nanoparticles with Tetrasulphide Bond to Enhance Plasmid DNA Delivery. Pharmaceutics, 15 (3) 1013, 1-11. doi: 10.3390/pharmaceutics15031013

Li, Wenrong, Dong, Siyuan, Chen, Qun, Chen, Chen and Dong, Zhaoheng (2023). Corrigendum to “Selenium may suppress peripheral blood mononuclear cell apoptosis by modulating HSP70 and regulate levels of SIRT1 through reproductive hormone secretion and oxidant stress in women suffering fluorosis” [Eur. J. Pharmacol. 878 (2020) 173098]. European Journal of Pharmacology, 943 175563, 175563. doi: 10.1016/j.ejphar.2023.175563

Zhou, Xin, Wang, Yanping, Chen, Wenyun, Zhang, Hongmin, He, Yirui, Dai, Han, Hu, Wenjing, Li, Ke, Zhang, Lili, Chen, Chen, Yang, Gangyi and Li, Ling (2023). Circulating HHIP levels in women with insulin resistance and PCOS: Effects of physical activity, cold stimulation and anti-diabetic drug therapy. Journal of Clinical Medicine, 12 (3) 888, 1-17. doi: 10.3390/jcm12030888

Pang, Huiwen, Huang, Xiangquan, Xu, Zhi Ping, Chen, Chen and Han, Felicity Y. (2023). Progress in oral insulin delivery by PLGA nanoparticles for the management of diabetes. Drug Discovery Today, 28 (1) 103393, 1-11. doi: 10.1016/j.drudis.2022.103393

Chen, Qun, Kao, Xibin, Gao, Yan, Chen, Jinghong, Dong, Zhaoheng and Chen, Chen (2023). Correction to: Nitric oxide-caused rabbit chondrocyte apoptosis is linked to cytoskeletal protein proteolysis anomaly through intracellular JNK and ERK signal pathways (Molecular & Cellular Toxicology, (2023), 19, 1, (71-79), 10.1007/s13273-022-00241-1). Molecular and Cellular Toxicology, 19 (1), 219-220. doi: 10.1007/s13273-022-00282-6

Wang, Hui, Li, Zhengzheng, Liu, Yinan, Zhang, Meng, Shi, Yawen, Zhang, Ying, Mi, Ge, Wang, Mengying, He, Ying, Chen, Yonghui, Chen, Chen and Chen, Jinghong (2023). Effects of Selenoprotein S knockdown on endoplasmic reticulum stress in ATDC5 cells and gene expression profiles in hypertrophic chondrocytes. Biological Trace Element Research, 201 (4), 1965-1976. doi: 10.1007/s12011-022-03313-4

Ran, Li-Sha, Wu, Ya-Zeng, Gan, Yi-Wen, Wang, Hong-Lian, Wu, Li-Juan, Zheng, Chun-Mei, Ming, Yao, Xiong, Ran, Li, Yong-Lin, Lei, Shi-Hang, Wang, Xue, Lao, Xiao-Qing, Zhang, Hong-Min, Wang, Li, Chen, Chen and Zhao, Chang-Ying (2023). Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease. Journal of Natural Medicines, 77 (1), 73-86. doi: 10.1007/s11418-022-01647-w

Han, Yanshuo, Chen, Chen and Zhang, Jian (2023). Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease. Frontiers in Genetics, 14 1233096, 1233096. doi: 10.3389/fgene.2023.1233096

Du, Chenping, Whiddett, Rani O., Buckle, Irina, Chen, Chen, Forbes, Josephine M. and Fotheringham, Amelia K. (2022). Advanced glycation end products and inflammation in type 1 diabetes development. Cells, 11 (21) 3503, 1-18. doi: 10.3390/cells11213503

Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132

Chen, Xiaolin, Huang, Lili, Cui, Ling, Xiao, Zhuoni, Xiong, Xiaoxing and Chen, Chen (2022). Sodium–glucose cotransporter 2 inhibitor ameliorates high fat diet-induced hypothalamic–pituitary–ovarian axis disorders. The Journal of Physiology, 600 (21), 4549-4568. doi: 10.1113/jp283259

Cui, Ling, Tan, Chunlu, Huang, Lili, Wang, Weihao, Huang, Zhengxiang, Geng, Fang, Wu, Mengjun, Chen, Xiaolin, Cowley, Michael, Roelfsema, Ferdinand and Chen, Chen (2022). Dapagliflozin partially restores reproductive function in MC4R KO obese female mice. Journal of Endocrinology, 254 (2), 65-76. doi: 10.1530/joe-21-0449

Zhang, Yanjun, Bai, Guangdong, Li, Xue, Nepal, Surya, Grobler, Marthie, Chen, Chen and Ko, Ryan K. L. (2022). Preserving privacy for distributed genome-wide analysis against identity tracing attacks. IEEE Transactions on Dependable and Secure Computing, 20 (4), 1-17. doi: 10.1109/tdsc.2022.3186672

Xing, JingJing and Chen, Chen (2022). Hyperinsulinemia: beneficial or harmful or both on glucose homeostasis. American Journal of Physiology-Endocrinology and Metabolism, 323 (1), E2-E7. doi: 10.1152/ajpendo.00441.2021

Huang, Zhengxiang, Xiao, Lan, Xiao, Yin and Chen, Chen (2022). The modulatory role of growth hormone in inflammation and macrophage activation. Endocrinology, 163 (8) bqac088, 1-12. doi: 10.1210/endocr/bqac088

Xiang, Ting, Zhang, Siliang, Li, Qinge, Li, Ling, Liu, Hua, Chen, Chen, Yang, Gangyi and Yang, Mengliu (2022). GPHB5 is a biomarker in women with metabolic syndrome: results from cross-sectional and intervention studies. Frontiers in Endocrinology, 13 893142, 1-12. doi: 10.3389/fendo.2022.893142

Iversen, Edwin S., Lipton, Gary, Hart, Steven N., Lee, Kun Y., Hu, Chunling, Polley, Eric C., Pesaran, Tina, Yussuf, Amal, LaDuca, Holly, Chao, Elizabeth, Karam, Rachid, Goldgar, David E., Couch, Fergus J. and Monteiro, Alvaro N. A. (2022). An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance. Npj Genomic Medicine, 7 (1) ARTN 35. doi: 10.1038/s41525-022-00302-3

Dong, Siyuan, Yang, Yanni, He, Biqi, Xu, Zhao, Zhou, Zhaoqiang, Wang, Jinhai, Chen, Chen and Chen, Qun (2022). Effect of sodium fluoride on reproductive function through regulating reproductive hormone level and circulating SIRT1 in female rats. Biological Trace Element Research, 201 (4), 1-12. doi: 10.1007/s12011-022-03283-7

Wu, Yihao, Jiang, Deying, Zhang, Hao, Yin, Fanxing, Guo, Panpan, Zhang, Xiaoxu, Bian, Ce, Chen, Chen, Li, Shuixin, Yin, Yuhan, Böckler, Dittmar, Zhang, Jian and Han, Yanshuo (2022). N1-methyladenosine (m1A) regulation associated with the pathogenesis of abdominal aortic aneurysm through YTHDF3 modulating macrophage polarization. Frontiers in Cardiovascular Medicine, 9 883155, 1-22. doi: 10.3389/fcvm.2022.883155

Ning, Yujie, Hu, Minhan, Chen, Sijie, Zhang, Feiyu, Yang, Xiaodong, Zhang, Qingping, Gong, Yi, Huang, Ruitian, Liu, Yanli, Chen, Feihong, Pei, Leilei, Guo, Xiong, Kang, Lianke, Wang, Xinyi, Zhang, Yan and Wang, Xi (2022). Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method. Environment International, 164 ARTN 107255, 107255. doi: 10.1016/j.envint.2022.107255

Chen, Qun, Kao, Xibin, Gao, Yan, Chen, Jinghong, Dong, Zhaoheng and Chen, Chen (2022). Nitric oxide-caused rabbit chondrocyte apoptosis is linked to cytoskeletal protein proteolysis anomaly through intracellular JNK and ERK signal pathways. Molecular and Cellular Toxicology, 19 (1), 1-2. doi: 10.1007/s13273-022-00241-1

Qiu, Sheng, Liang, Zerong, Wu, Qinan, Wang, Miao, Yang, Mengliu, Chen, Chen, Zheng, Hongting, Zhu, Zhiming, Li, Ling and Yang, Gangyi (2022). Hepatic lipid accumulation induced by a high-fat diet is regulated by Nrf2 through multiple pathways. The FASEB Journal, 36 (5) e22280, e22280. doi: 10.1096/fj.202101456R

Li, Jiaxi, Huang, Pu, Xiong, Jing, Liang, Xinyue, Li, Mei, Ke, Hao, Chen, Chunli, Han, Yang, Huang, Yanhong, Zhou, Yan, Luo, Ziqiang, Feng, Dandan and Chen, Chen (2022). Serum levels of ghrelin and LEAP2 in patients with type 2 diabetes mellitus: correlation with circulating glucose and lipids. Endocrine Connections, 11 (5) e220012, 1-9. doi: 10.1530/ec-22-0012

Dai, Bo, Wang, Ziyang, Lu, Qian, Ma, Hucheng, Guissi, Nida El Islem, Wang, Yiqing, Wu, Xingyu and Cai, Huiming (2022). Unexpected detection of a submillimeter early hepatocellular carcinoma focus by intraoperative near-infrared fluorescence imaging-a case report. Annals of Translational Medicine, 10 (10) ARTN 617. doi: 10.21037/atm-22-2338

Darst, Burcu F., Hughley, Raymond, Pfennig, Aaron, Hazra, Ujani, Fan, Caoqi, Wan, Peggy, Sheng, Xin, Xia, Lucy, Andrews, Caroline, Chen, Fei, Berndt, Sonja, Kote-Jarai, Zsofia, Govindasami, Koveela, Bensen, Jeannette T., Ingles, Sue A., Rybicki, Benjamin A., Nemesure, Barbara, John, Esther M., Fowke, Jay H., Huff, Chad D., Strom, Sara S., Isaacs, William B., Park, Jong Y., Zheng, Wei, Ostrander, Elaine A., Walsh, Patrick C., Carpten, John, Sellers, Thomas A., Yamoah, Kosj ... Haiman, Christopher A. (2022). A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry. European Urology, 81 (5), 458-462. doi: 10.1016/j.eururo.2021.12.023

Xing, Jing-Jing, Mi, Xiao-Jie, Hou, Jin-Gang, Cai, En-Bo, Zheng, Si-Wen, Wang, Shi-Han, Wang, Zi, Chen, Chen and Li, Wei (2022). Maltol mitigates cisplatin-evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro. Phytotherapy Research, 36 (4), 1724-1735. doi: 10.1002/ptr.7405

Zhao, Anjiang, Li, Dan, Mao, Xiongmin, Yang, Mengliu, Deng, Wuquan, Hu, Wenjing, Chen, Chen, Yang, Gangyi and Li, Ling (2022). GNG2 acts as a tumor suppressor in breast cancer through stimulating MRAS signaling. Cell Death and Disease, 13 (3) 260, 260. doi: 10.1038/s41419-022-04690-3

Li, Kejia, Liang, Zerong, Xu, Weiwei, Dai, Han, Tian, Mingyuan, Li, Ling, Liu, Hua, Chen, Chen, Liu, Dongfang, Zheng, Hongting, Zhu, Zhiming, Yang, Gangyi and Yang, Mengliu (2022). CTRP7 is a biomarker related to insulin resistance and oxidative stress: cross-sectional and intervention studies in vivo and in vitro. Oxidative Medicine and Cellular Longevity, 2022 6877609, 1-17. doi: 10.1155/2022/6877609

Yin, Fanxing, Zhang, Hao, Guo, Panpan, Wu, Yihao, Zhao, Xinya, Li, Fangjun, Bian, Ce, Chen, Chen, Han, Yanshuo and Liu, Kun (2022). Comprehensive analysis of key m6A modification related genes and immune infiltrates in human aortic dissection. Frontiers in Cardiovascular Medicine, 9 831561, 831561. doi: 10.3389/fcvm.2022.831561

Chen, Chen, Li, Wenzhi, Yin, Mingru, Li, Menghui, Wu, Ling, Si, Jiqiang, Zhao, Leiwen, Li, Bin, Yan, Zheng and Lyu, Qifeng (2022). Does the cell number of 0PN embryos on day 3 affect pregnancy and neonatal outcomes following single blastocyst transfer?. BMC Pregnancy and Childbirth, 22 (1) 200, 1-9. doi: 10.1186/s12884-022-04492-7

Xu, Yangting, Chen, Chen, Feng, Dandan and Luo, Ziqiang (2022). A survey of college students on the preference for online teaching videos of variable durations in online flipped classroom. Frontiers in Public Health, 10 838106, 838106. doi: 10.3389/fpubh.2022.838106

Chen, Xiaolin, Xiao, Zhuoni, Cai, Yuli, Huang, Lili and Chen, Chen (2022). Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis. Trends in Endocrinology and Metabolism, 33 (3), 206-217. doi: 10.1016/j.tem.2021.12.004

Tong, Yue, Xu, Sai, Huang, Lili and Chen, Chen (2022). Obesity and insulin resistance: Pathophysiology and treatment. Drug Discovery Today, 27 (3), 822-830. doi: 10.1016/j.drudis.2021.11.001

Qiu, Jiaxin, Du, Tong, Chen, Chen, Lyu, Qifeng, Mol, Ben W., Zhao, Ming and Kuang, Yanping (2022). Impact of uterine malformations on pregnancy and neonatal outcomes of IVF/ICSI-frozen embryo transfer. Human Reproduction, 37 (3), 428-446. doi: 10.1093/humrep/deac003

Chen, Chen, Yu, Sha, Yu, Weina, Yan, Zhiguang, Jin, Wei, Si, Jiqiang, Li, Menghui, Cai, Renfei, Li, Dongying, Wang, Li, Chen, Qiuju, Kuang, Yanping, Lyu, Qifeng and Long, Hui (2022). Luteinizing hormone suppression by progestin-primed ovarian stimulation is associated with higher implantation rate for patients with polycystic ovary syndrome who underwent in vitro fertilization/intracytoplasmic sperm injection cycles: comparing with short protocol. Frontiers in Physiology, 12 744968. doi: 10.3389/fphys.2021.744968

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Yang, Jin-Kui, Lu, Jing, Yuan, Sha-Sha, Asan,, Cao, Xi, Qiu, Hai-Yan, Shi, Ting-Ting, Yang, Fang-Yuan, Li, Qian, Liu, Cui-Ping, Wu, Qian, Wang, Yu-Hui, Huang, Hai-Xia, Kayoumu, Abudurexiti, Feng, Jian-Ping, Xie, Rong-Rong, Zhu, Xiao-Rong, Liu, Chang, Yang, Guang-Ran, Zhang, Ming-Rong, Xie, Chun-Lan, Chen, Chen, Zhang, Bo, Liu, George, Zhang, Xiu-Qing and Xu, Aimin (2018). From hyper- to hypoinsulinemia and diabetes: effect of KCNH6 on insulin secretion. Cell Reports, 25 (13), 3800-3810. doi: 10.1016/j.celrep.2018.12.005

Xu, Xing-Yue, Wang, Zi, Ren, Shen, Leng, Jing, Hu, Jun-nan, Liu, Zhi, Chen, Chen and Li, Wei (2018). Improved protective effects of American ginseng berry against acetaminophen-induced liver toxicity through TNF-α-mediated caspase-3/-8/-9 signaling pathways. Phytomedicine, 51, 128-138. doi: 10.1016/j.phymed.2018.09.234

Fu, Cheng-lin, Liu, Ying, Leng, Jing, Zhang, Jing, He, Yu-fang, Chen, Chen, Wang, Zi and Li, Wei (2018). Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice. Biomedicine and Pharmacotherapy, 107, 867-877. doi: 10.1016/j.biopha.2018.08.082

Mi, Xiao-jie, Hou, Jin-gang, Wang, Zi, Han, Ye, Ren, Shen, Hu, Jun-nan, Chen, Chen and Li, Wei (2018). The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways. Scientific Reports, 8 (1) 15922, 15922. doi: 10.1038/s41598-018-34156-6

Zhang, Xinli, Yang, Jin-Kui and Chen, Chen (2018). Enhanced pulsatile growth hormone secretion and altered metabolic hormones by in vivo hexarelin treatment in streptozotocin-induced diabetic rats. International Journal of Molecular Sciences, 19 (10) 3067, 3067. doi: 10.3390/ijms19103067

Zhang, Weizhe, Hou, Jingang, Yan, Xiaotong, Leng, Jing, Li, Rongyan, Zhang, Jing, Xing, Jingjing, Chen, Chen, Wang, Zi and Li, Wei (2018). Platycodon grandiflorum saponins ameliorate cisplatin-induced acute nephrotoxicity through the NF-κB-mediated inflammation and PI3K/Akt/apoptosis signaling pathways. Nutrients, 10 (9) 1328, 1-16. doi: 10.3390/nu10091328

Zhen, Xi May, Li, Xue and Chen, Chen (2018). Metformin versus insulin for gestational diabetes: the reporting of ethnicity and a meta-analysis combining English and Chinese literatures. Obesity Medicine, 11, 48-58. doi: 10.1016/j.obmed.2018.08.001

Leng, Jing, Wang, Zi, Fu, Cheng-Lin, Zhang, Jing, Ren, Shen, Hu, Jun-Nan, Jiang, Shuang, Wang, Ying-Ping, Chen, Chen and Li, Wei (2018). NF-κB and AMPK/PI3K/Akt signaling pathways are involved in the protective effects of Platycodon grandiflorum saponins against acetaminophen-induced acute hepatotoxicity in mice. Phytotherapy Research, 32 (11), 2235-2246. doi: 10.1002/ptr.6160

May Zhen, Xi, Li, Xue and Chen, Chen (2018). Longer-term outcomes in offspring of GDM mothers treated with metformin versus insulin. Diabetes Research and Clinical Practice, 144, 82-92. doi: 10.1016/j.diabres.2018.07.002

Zhou, Yan-Dan, Hou, Jin-Gang, Liu, Wei, Ren, Shen, Wang, Ying-Ping, Zhang, Rui, Chen, Chen, Wang, Zi and Li, Wei (2018). 20(R)-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis. International Immunopharmacology, 59, 21-30. doi: 10.1016/j.intimp.2018.03.030

Hidalgo, Alejandro, Glass, Nick, Ovchinnikov, Dmitry, Yang, Seung-Kwon, Zhang, Xinli, Mazzone, Stuart, Chen, Chen, Wolvetang, Ernst and Cooper-White, Justin (2018). Modelling ischemia-reperfusion injury (IRI) in vitro using metabolically matured induced pluripotent stem cell-derived cardiomyocytes. APL Bioengineering, 2 (2) 026102, 026102. doi: 10.1063/1.5000746

Wu, Yanheng, Gu, Wenyi, Chen, Chen, Do, Son Trong and Xu, Zhi Ping (2018). Optimization of formulations consisting of layered double hydroxide nanoparticles and small interfering RNA for efficient knockdown of the target gene. ACS Omega, 3 (5), 4871-4877. doi: 10.1021/acsomega.8b00397

Yan, Xiao-Tong, Sun, Yin-Shi, Ren, Shen, Zhao, Li-Chun, Liu, Wen-Cong, Chen, Chen, Wang, Zi and Li, Wei (2018). Dietary α-mangostin provides protective effects against acetaminophen-induced hepatotoxicity in mice via Akt/mTOR-mediated inhibition of autophagy and apoptosis. International Journal of Molecular Sciences, 19 (5) 1335, 1335. doi: 10.3390/ijms19051335

McDonald, Hayley, Peart, Jason, Kurniawan, Nyoman, Galloway, Graham, Royce, Simon, Samuel, Chrishan S. and Chen, Chen (2018). Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction. Physiological Reports, 6 (9) e13699, e13699. doi: 10.14814/phy2.13699

Wang, Jie, Gu, Wenyi and Chen, Chen (2018). Knocking down insulin receptor in pancreatic beta cell lines with lentiviral-small hairpin RNA reduces glucose-stimulated insulin secretion via decreasing the gene expression of insulin, GLUT2 and Pdx1. International Journal of Molecular Sciences, 19 (4) 985, 985. doi: 10.3390/ijms19040985

Li, Wei and Chen, Chen (2018). Response to the Comments on Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice. Journal of Agricultural and Food Chemistry, 66 (7), 1734-1735. doi: 10.1021/acs.jafc.7b05975

Zhang, Xinli, Qu, Linbing, Chen, Ling and Chen, Chen (2018). Improvement of cardiomyocyte function by in vivo hexarelin treatment in streptozotocin-induced diabetic rats. Physiological Reports, 6 (4) e13612, e13612. doi: 10.14814/phy2.13612

Mosa, Rasha, Huang, Lili, Li, Hongzhuo, Grist, Michael, LeRoith, Derek and Chen, Chen (2018). Long-term treatment with the ghrelin receptor antagonist [D-Lys3]-GHRP-6 does not improve glucose homeostasis in nonobese diabetic MKR mice. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 314 (1), R71-R83. doi: 10.1152/ajpregu.00157.2017

Chen, Chen (2018). Meet our regional editor. Current Medicinal Chemistry, 25 (7), 771-771. doi: 10.2174/092986732507180315155402

Chen, Xiao-Lin and Chen, Chen (2017). Frozen section with improved H&E staining for follicular morphometric analysis of mouse ovary in oestrus cycle. Sheng li xue bao [Acta physiologica Sinica], 69 (6), 781-784.

Chen, Jiezhong, Huang, Xu-Feng, Shao, Renfu, Chen, Chen and Deng, Chao (2017). Molecular Mechanisms of Antipsychotic Drug-Induced Diabetes. Frontiers in Neuroscience, 11 (NOV) 643, 643. doi: 10.3389/fnins.2017.00643

Shi, Ting-Ting, Yang, Fang-Yuan, Liu, Chang, Cao, Xi, Lu, Jing, Zhang, Xue-Lian, Yuan, Ming-Xia, Chen, Chen and Yang, Jin-Kui (2017). Angiotensin-converting enzyme 2 regulates mitochondrial function in pancreatic β-cells. Biochemical and Biophysical Research Communications, 495 (1), 860-866. doi: 10.1016/j.bbrc.2017.11.055

Qiu, Han, Yang, Jin-Kui and Chen, Chen (2017). Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng Li Xue Bao : [Acta physiologica Sinica], 69 (5), 541-556.

Ma, Zhi-na, Liu, Zhi, Wang, Zi, Ren, Shen, Tang, Shan, Wang, Ying-ping, Xiao, Sheng-yuan, Chen, Chen and Li, Wei (2017). Supplementation of American ginseng berry extract mitigated cisplatin-evoked nephrotoxicity by suppressing ROS-mediated activation of MAPK and NF-κB signaling pathways. Food and Chemical Toxicology, 110, 62-73. doi: 10.1016/j.fct.2017.10.006

Huang, Xiao-Ting, Yue, Shao-Jie, Li, Chen, Huang, Yan-Hong, Cheng, Qing-Mei, Li, Xiao-Hong, Hao, Cai-Xia, Wang, Ling-Zhi, Xu, Jian-Ping, Ji, Ming, Chen, Chen, Feng, Dan-Dan and Luo, Zi-Qiang (2017). A Sustained Activation of Pancreatic NMDARs Is a Novel Factor of β-Cell Apoptosis and Dysfunction. Endocrinology, 158 (11), 3900-3913. doi: 10.1210/en.2017-00366

Mcdonald, H., Peart, J., Kurniawan, N.D., Galloway, G., Royce, S.G., Samuel, C.S. and Chen, C. (2017). [OP.3B.05] Hexarelin preserves myocardial function and reduces inflammation and fibrosis in a mouse model of myocardial ischemia reperfusion. Journal of Hypertension, 35 (Supplement 2), e29-e29. doi: 10.1097/01.hjh.0000523053.36429.97

Xu, Chun, Lei, Chang, Huang, Lili, Zhang, Jun, Zhang, Hongwei, Song, Hao, Yu, Meihua, Wu, Yeda, Chen, Chen and Yu, Chengzhong (2017). Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy. Chemistry of Materials, 29 (18), 7725-7732. doi: 10.1021/acs.chemmater.7b01804

Mosa, Rasha, Huang, Lili, Wu, Yeda, Fung, Chungyan, Mallawakankanamalage, Oshini, LeRoith, Derek and Chen, Chen (2017). Hexarelin, a Growth Hormone Secretagogue, Improves Lipid Metabolic Aberrations in Nonobese Insulin-Resistant Male MKR Mice. Endocrinology, 158 (10), 3174-3187. doi: 10.1210/en.2017-00168

Webster, Julie A., Yang, Zhe, Kim, Yu-Hee, Loo, Dorothy, Mosa, Rasha M., Li, Hongzhuo and Chen, Chen (2017). Collagen beta (1-O) galactosyltransferase 1 (GLT25D1) is required for the secretion of high molecular weight adiponectin and affects lipid accumulation. Bioscience Reports, 37 (3) BSR20170105, BSR20170105. doi: 10.1042/BSR20170105

Wu, Yanheng, Chen, Mingshui, Wu, Peihong, Chen, Chen, Xu, Zhi Ping and Gu, Wenyi (2017). Increased PD-L1 expression in breast and colon cancer stem cells. Clinical and Experimental Pharmacology and Physiology, 44 (5), 602-604. doi: 10.1111/1440-1681.12732

Gatford, Kathryn L., Muhlhausler, Beverly S., Huang, Lili, Sim, Pamela Su-Lin, Roberts, Claire T., Velhuis, Johannes D. and Chen, Chen (2017). Rising maternal circulating GH during murine pregnancy suggests placental regulation. Endocrine Connections, 6 (4), 260-266. doi: 10.1530/EC-17-0032

Yang, Hao Jie, Zhang, Ying, Wang, Zhi Lun, Xue, Sen Hai, Li, Si Yuan, Zhou, Xiao Rong, Zhang, Meng, Fang, Qian, Wang, Wen Jun, Chen, Chen, Deng, Xiang Hua and Chen, Jing Hong (2017). Increased Chondrocyte Apoptosis in Kashin-Beck Disease and Rats Induced by T-2 Toxin and Selenium Deficiency. Biomedical and Environmental Sciences, 30 (5), 351-362. doi: 10.3967/bes2017.046

Maugham, Michelle L., Thomas, Patrick B., Crisp, Gabrielle J., Philp, Lisa K., Shah, Esha T., Herington, Adrian C., Chen, Chen, Gregory, Laura S., Nelson, Colleen C., Seim, Inge, Jeffery, Penny L. and Chopin, Lisa K. (2017). Insights from engraftable immunodeficient mouse models of hyperinsulinaemia. Scientific Reports, 7 (1) 00443, 491. doi: 10.1038/s41598-017-00443-x

Huang, Xiao-Ting, Li, Chen, Peng, Xiang-Ping, Guo, Jia, Yue, Shao-Jie, Liu, Wei, Zhao, Fei-Yan, Han, Jian-Zhong, Huang, Yan-Hong, Yang-Li, Cheng, Qing-Mei, Zhou, Zhi-Guang, Chen, Chen, Feng, Dan-Dan and Luo, Zi-Qiang (2017). An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes. Scientific Reports, 7 (1) 44120, 44120. doi: 10.1038/srep44120

Chen, Xiaolin, Huang, Lili , Tan, Hwee Y., Li, Hongzhuo, Wan, Ying, Cowley, Michael, Veldhuis, Johannes D. and Chen, Chen (2017). Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice. Reproduction, 153 (3), 267-276. doi: 10.1530/REP-16-0341

Yang, Jin-Kui, Wang, Ying-Ying, Liu, Chang, Shi, Ting-Ting, Lu, Jing, Cao, Xi, Yang, Fang-Yuan, Feng, Jian-Ping , Chen, Chen, Ji, Li-Non and Xu, Aimin (2017). Urine proteome specific for eye damage can predict kidney damage in patients with type 2 diabetes: a case-control and a 5.3-year prospective cohort study. Diabetes Care, 40 (2), 253-260. doi: 10.2337/dc16-1529

Zhou, Li, Gao, Jing and Chen, Chen (2017). Feasibility analysis of triglyceride as a surrogate marker for insulin resistance in Chinese women with polycystic ovary syndrome. Journal of Shanghai Jiaotong University (Medical Science), 37 (1), 60-63. doi: 10.3969/j.issn.1674-8115.2017.01.013

Chen, Chen (2017). Meet our editorial board member. Current Drug Targets, 18 (7). doi: 10.2174/138945011807170428181919

Liu, Li, Zhao, Fan, Liu, Wei, Zhu, Tong, Zhang, John Z. H., Chen, Chen, Dai, Zhihui, Peng, Huisheng, Huang, Jun-Long, Hu, Qin, Bu, Wenbo and Tian, Yang (2017). An electrochemical biosensor with dual signal outputs: toward simultaneous quantification of pH and O2 in the brain upon ischemia and in a tumor during cancer starvation therapy. Angewandte Chemie (International Edition), 56 (35), 10471-10475. doi: 10.1002/anie.201705615

Tan, H. Y., Steyn, F. J., Huang, L., Cowley, M., Veldhuis, J. D. and Chen, C. (2016). Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone. Journal of Physiology, 594 (24), 7309-7326. doi: 10.1113/JP272770

Yeo, S. -H., Kyle, V., Morris, P. G., Jackman, S., Sinnett-Smith, L. C., Schacker, M., Chen, C. and Colledge, W. H. (2016). Visualisation of Kiss1 neurone distribution using a Kiss1-CRE transgenic mouse. Journal of Neuroendocrinology, 28 (11), 1-12. doi: 10.1111/jne.12435

Li, Wei, Yan, Meng-Han, Liu, Ying, Liu, Zhi, Wang, Zi, Chen, Chen, Zhang, Jing and Sun, Yin-Shi (2016). Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis. Nutrients, 8 (9) 566, 566. doi: 10.3390/nu8090566

Steyn, Frederik J., Tolle, Virginie, Chen, Chen and Epelbaum, Jacques (2016). Neuroendocrine regulation of growth hormone secretion. Comprehensive Physiology, 6 (2), 687-735. doi: 10.1002/cphy.c150002

Cheng, Feifei, Zhao, Lu, Wu, Yuanyuan, Huang, Tiantian, Yang, Gangyi, Zhang, Zhanyu, Wu, Yijia, Jia, Fang, Wu, Jinlin, Chen, Chen and Liu, Dongfang (2016). Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment. Clinical Endocrinology, 84 (3), 386-393. doi: 10.1111/cen.12950

Zhao, Yan, Zhang, Xinli, Chen, Jiezhong, Lin, Chao, Shao, Renfu, Yan, Chunxia and Chen, Chen (2016). Hexarelin protects rodent pancreatic B-cells function from cytotoxic effects of streptozotocin involving mitochondrial signalling pathways in vivo and in vitro. PLoS ONE, 11 (2) e0149730, e0149730. doi: 10.1371/journal.pone.0149730

Zhang, Yibei, Qiao, Haiou, Chen, Chen, Wang, Zhilun and Xia, Xiaodong (2016). Determination of nitrofurans metabolites residues in aquatic products by ultra-performance liquid chromatography-tandem mass spectrometry. Food Chemistry, 192, 612-617. doi: 10.1016/j.foodchem.2015.07.035

Jiang, Zhihui, Chen, Chen, Wang, Jian, Xie, Wenyan, Wang, Meng, Li, Xinsheng and Zhang, Xiaoying (2016). Purple potato (Solanum tuberosum L.) anthocyanins attenuate alcohol-induced hepatic injury by enhancing antioxidant defense. Journal of Natural Medicines, 70 (1), 45-53. doi: 10.1007/s11418-015-0935-3

Xie, T. Y., Ngo, S. T., Veldhuis, J. D., Jeffery, P. L., Chopin, L. K., Tschop, M., Waters, M. J., Tolle, V., Epelbaum, J., Chen, C. and Steyn, F. J. (2015). Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release of growth hormone in mice. Journal of Neuroendocrinology, 27 (12), 872-886. doi: 10.1111/jne.12327

Chen, Jiezhong, Xu, Tiefeng and Chen, Chen (2015). The critical roles of miR-21 in anti-cancer effects of curcumin. Annals of Translational Medicine, 3 (21) 330, 330. doi: 10.3978/j.issn.2305-5839.2015.09.20

Lv, Lixia, Chen, Hewen, Sun, Jiaying, Lu, Di, Chen, Chen and Liu, Dongfang (2015). PRMT1 promotes glucose toxicity-induced β cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells. Endocrine, 49 (3), 669-682. doi: 10.1007/s12020-015-0543-8

Carrasco-Pozo, Catalina, Gotteland, Martin, Castillo, Rodrigo L. and Chen, Chen (2015). 3,4-dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, protects against pancreatic β-cells dysfunction induced by high cholesterol. Experimental Cell Research, 334 (2), 270-282. doi: 10.1016/j.yexcr.2015.03.021

Mosa, Rasha Mofeed Habeeb, Zhang, Zhen, Shao, Renfu, Deng, Chao, Chen, Jiezhong and Chen, Chen (2015). Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases. Endocrine, 49 (2), 307-323. doi: 10.1007/s12020-015-0531-z

Yi K.J., So K.H., Hata Y., Suzuki Y., Kato D., Watanabe K., Aso H., Kasahara Y., Nishimori K., Chen, Chen, Katoh K. and Roh S.G. (2015). The regulation of oxytocin receptor gene expression during adipogenesis. Journal of Neuroendocrinology, 27 (5), 335-342. doi: 10.1111/jne.12268

Chen, Jiezhong, Gu, Wenyi, Yang, Lei, Chen, Chen, Shao, Renfu, Xu, Kewei and Xu, Zhi Ping (2015). Nanotechnology in the management of cervical cancer. Reviews in Medical Virology, 25 (S1), 72-83. doi: 10.1002/rmv.1825

Guillou, Anne, Romano, Nicola, Steyn, Frederik, Abitbol, Karine, Le Tissier, Paul, Bonnefont, Xavier, Chen, Chen, Mollard, Patrice and Martin, Agnès O. (2015). Assessment of lactotroph axis functionality in mice: longitudinal monitoring of PRL secretion by ultrasensitive-ELISA. Endocrinology, 156 (5), 1-7. doi: 10.1210/en.2014-1571

Chen, Jiezhong, Shao, Renfu and Chen, Chen (2015). Possible therapeutic implication of PDL-1/PD-1 axis in endometrial cancer. Journal of Solid Tumors, 5 (1), 10-17. doi: 10.5430/jst.v5n1p10

Chen, Chen (2015). Meet the editorial board. Current Drug Targets, 16 (3), 179-179. doi: 10.2174/138945011603150313234542

Chen, Chen (2015). Meet our editorial board member. Current Drug Targets, 16 (14), 1563-1563. doi: 10.2174/138945011614151119110133

Huang, Lili, Tan, Hwee Y., Fogarty, Matthew J., Andrews, Zane B., Veldhuis, Johannes D., Herzog, Herbert, Steyn, Frederik J. and Chen, Chen (2014). Actions of NPY, and its Y1 and Y2 receptors on pulsatile growth hormone secretion during the fed and fasted state. Journal of Neuroscience, 34 (49), 16309-16319. doi: 10.1523/JNEUROSCI.4622-13.2014

Ovchinnikov, Dmitry A.,, Hidalgo, Alejandro, Yang, Seung-Kwon, Zhang, Xinli, Hudson, James, Mazzone, Stuart B., Chen, Chen, Cooper-White, Justin J. and Wolvetang, Ernst J. (2014). Isolation of contractile cardiomyocytes from human pluripotent stem-cell-derived cardiomyogenic cultures using a human NCX1-EGFP reporter. Stem Cells and Development, 24 (1), 11-20. doi: 10.1089/scd.2014.0195

Chen, Jiezhong, Zhao, Kong-Nan, Li, Rui, Shao, Renfu and Chen, Chen (2014). Activation of PI3K/Akt/mTOR pathway and dual inhibitors of PI3K and mTOR in endometrial cancer. Current Medicinal Chemistry, 21 (26), 3070-3080. doi: 10.2174/0929867321666140414095605

Chen, Chen, Chen, Jiezhong and Zhao, Kong-Nan (2014). Signalling pathways in anti-cancer drug resistance. Current Medicinal Chemistry, 21 (26), 3007-3008. doi: 10.2174/092986732126140804160443

Zhou, Xiaorong, Wang, Zhilun, Chen, Jinghong, Wang, Wei, Song, Daiqing, Li, Siyuan, Yang, Haojie, Xue, Senhai and Chen, Chen (2014). Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency. Rheumatology International, 34 (7), 995-1004. doi: 10.1007/s00296-013-2862-5

Chen, Jiezhong, Elfiky, Aymen, Han, Mei, Chen, Chen and Saif, M. Wasif (2014). The role of Src in colon cancer and its therapeutic implications. Clinical Colorectal Cancer, 13 (1), 5-13. doi: 10.1016/j.clcc.2013.10.003

Li, Shengbin, Li, Bo, Cheng, Cheng, Xiong, Zijun, Liu, Qingbo, Lai, Jianghua, Carey, Hannah V., Zhang, Qiong, Zheng, Haibo, Zheng, Haibo, Wei, Shuguang, Zhang, Hongbo, Chang, Liao, Liu, Shiping, Zhang, Shanxin, Yu, Bing, Zeng, Xiaofan, Huo, Yong, Nie, Wenhui, Guo, Youmin, Chen, Teng, Han, Jiuqiang, Wang, Jian, Wang, Jun, Chen, Chen, Liu, Jiankang, Stambrook, Peter J., Xu, Ming, Zhang, Guojie ... Yan, Jianqun (2014). Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. Genome Biology, 15 (557) 557, 1-16. doi: 10.1186/s13059-014-0557-1

Chen, Jiezhong, Zhao, Kong-Nan and Chen, Chen (2014). The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis. Annals of Translational Medicine, 2 (1) 7, 7-7. doi: 10.3978/j.issn.2305-5839.2013.03.02

Hassouna, Rim, Zizzari, Philippe, Tomasetto, Catherine, Veldhuis, Johannes D., Fiquet, Oriane, Labarthe, Alexandra, Cognet, Julie, Steyn, Frederik, Chen, Chen, Epelbaum, Jacques and Tolle, Virginie (2014). An early reduction in GH peak amplitude in preproghrelin deficient male mice has a minor impact on linear growth. Endocrinology, 155 (9), 3561-3571. doi: 10.1210/en.2014-1126

Manzanero, Silvia, Erion, Joanna R., Santro, Tomislay, Steyn, Frederik J., Chen, Chen, Arumugam, Thiruma V. and Stranahan, Alexis M. (2014). Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery. Journal of Cerebral Blood Flow and Metabolism, 34 (5), 897-905. doi: 10.1038/jcbfm.2014.36

Chen, Jinghong, Cao, Junling, Wang, Zhilun, Ma, Tianyou, Wang, Mengying, He, Ying, Yang, Zhantian and Chen, Chen (2014). Correlation of matrix metalloproteinases and Kashin-Beck disease. Chinese Journal of Endemiology, 33 (4), 357-362.

Chen, Chen, Chen, Jinghong, Cao, Junling, Wang, Wei, Zhang, Zengtie, Yang, Zhantian, Yu, Boquan and Ma, Tianyou (2014). 大骨节病儿童软骨白细胞介素-1β、白细胞介素-6及肿瘤坏死因子-α的表达. Chinese Journal of Endemiology, 33 (4), 363-366. doi: 10.3760/cma.j.issn.2095-4255.2014.04.003

Steyn F.J., Wan Y., Clarkson J., Veldhuis J.D., Herbison A.E. and Chen C. (2013). Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice. Endocrinology, 154 (12), 4939-4945. doi: 10.1210/en.2013-1502

Steyn, F. J., Lee, Kevin, Fogarty, M. J., Veldhuis, J. D., McCombe, P. A,, Bellingham, M. C., Ngo, S. T. and Chen, C (2013). Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology, 154 (12), 4695-4706. doi: 10.1210/en.2013-1570

Chen J., Crawford R., Chen C. and Xiao Y. (2013). The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration. Tissue Engineering - Part B: Reviews, 19 (6), 516-528. doi: 10.1089/ten.teb.2012.0672

Xu Zhao, Wang Zhou, Li Jian-jun, Chen Chen, Zhang Ping-chuan, Dong Lu, Chen Jing-hong, Chen Qun, Zhang Xiao-tian and Wang Zhi-lun (2013). Protective effects of selenium on oxidative damage and oxidative stress related gene expression in rat liver under chronic poisoning of arsenic. Food and Chemical Toxicology, 58, 1-7. doi: 10.1016/j.fct.2013.03.048

Zhao, Yu-Feng, Wang, Li, Zha, Dingjun, Qiao, Li, Lu, Lianjun, Yu, Jun, Qu, Ping, Sun, Qiang, Qiu, Jianhua and Chen, Chen (2013). GW9508 inhibits insulin secretion by activating ATP-sensitive potassium channels in rat pancreatic beta-cells. Journal of Molecular Endocrinology, 51 (1), 69-77. doi: 10.1530/JME-13-0019

Steyn, F. J., Xie, T. Y., Huang, L., Ngo, S. T., Veldhuis, J. D., Waters, M. J. and Chen, C. (2013). Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. Journal of Endocrinology, 218 (2), 233-244. doi: 10.1530/JOE-13-0084

Fung, Jenny N. T., Jeffery, Penny L., Lee, John D., Seim, Inge, Roche, Deborah, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2013). Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 305 (2), E305-E313. doi: 10.1152/ajpendo.00156.2013

Chen, Jiezhong, Shao, Renfu, Zhang, Xu Dong and Chen, Chen (2013). Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics. International Journal of Nanomedicine, 8 (1), 2677-2688. doi: 10.2147/IJN.S45429

Zhao, Yufeng, Wang, Li, Qiu, Jianhua, Zha, Dingjun, Sun, Qiang and Chen, Chen (2013). Linoleic acid stimulates [Ca2+]i increase in rat pancreatic Beta-Cells through both membrane receptor- and intracellular metabolite-mediated pathways. PLoS One, 8 (4) e60255, e60255.1-e60255.9. doi: 10.1371/journal.pone.0060255

Wu, Jianghong, Chen, Chen and Zhao, Kong-Nan (2013). Phosphatidylinositol 3-kinase signaling as a therapeutic target for cervical cancer. Current Cancer Drug Targets, 13 (2), 143-156. doi: 10.2174/1568009611313020004

Du, Lai-Ling, Xie, Jia-Zhao, Cheng, Xiang-Shu, Li, Xiao-Hong, Kong, Fan-Li, Jiang, Xia, Ma, Zhi-Wei, Wang, Jian-Zhi, Chen, Chen and Zhou, Xin-Wen (2013). Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi. Age, 36 (2), 613-623. doi: 10.1007/s11357-013-9592-1

Zou, H., Gan, X. L., Linghu, L. J., Chen, C., Hu, L. N. and Zhang, Y. (2013). Intense nanosecond pulsed electric fields promote cancer cell apoptosis through centrosome-dependent pathway involving reduced level of PLK1. European Review for Medical and Pharmacological Sciences, 17 (2), 152-160.

Gu, Wenyi, Chen, Chen and Zhao, Kong-Nan (2013). Obesity-associated endometrial and cervical cancers. Frontiers in Bioscience, 5 (1) E600, 109-118. doi: 10.2741/e600

Zhao, Yufeng, Zha, Dingjun, Wang, Li, Qiao, Li, Lu, Lianjun, Mei, Lin, Chen, Chen and Qiu, Jianhua (2013). Phenotypic characterization of GPR120-expressing cells in the interstitial tissue of pancreas. Tissue and Cell, 45 (6), 421-427. doi: 10.1016/j.tice.2013.07.005

Chen, Jiezhong, Chi, Mengna, Chen, Chen and Zhang, Xu Dong (2013). Obesity and melanoma: exploring molecular links. Journal of Cellular Biochemistry, 114 (9), 1955-1961. doi: 10.1002/jcb.24549

Tan, H. Y., Huang, L., Simmons, D., Veldhuis, J. D., Steyn, F. J. and Chen, C. (2013). Hypothalamic distribution of somatostatin mRNA expressing neurones relative to pubertal and adult changes in pulsatile growth hormone secretion in mice. Journal of Neuroendocrinology, 25 (10), 910-919. doi: 10.1111/jne.12078

Ling, Liang-han, Khammy, Ouda, Byrne, Melissa, Amirahmadi, Fatemah, Foster, Anna, Li, Gefeng, Zhang, Linda, dos Remedios, Cris, Chen, Chen and Kaye, David M. (2012). Irregular rhythm adversely influences calcium handling in ventricular myocardium: implications for the interaction between heart failure and atrial fibrillation. Circulation: Heart Failure, 5 (6), 786-793. doi: 10.1161/CIRCHEARTFAILURE.112.968321

Rao, J. R., Keating, D. J., Chen, C. and Parkington, H. C. (2012). Adiponectin increases insulin content and cell proliferation in MIN6 cells via PPAR gamma-dependent and PPAR gamma-independent mechanisms. Diabetes Obesity & Metabolism, 14 (11), 983-989. doi: 10.1111/j.1463-1326.2012.01626.x

Ma, Yi, Zhang, Lin, Launikonis, Bradley S. and Chen, Chen (2012). Growth hormone secretagogues preserve the electrophysiological properties of mouse cardiomyocytes isolated from in Vitro ischemia/reperfusion heart. Endocrinology, 153 (11), 5480-5490. doi: 10.1210/en.2012-1404

Xu, Xiangbin, Ding, Fan, Pang, Jinjiang, Gao, Xue, Xu, Rong-Kun, Hao, Wei, Cao, Ji-Min and Chen, Chen (2012). Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. American Journal of Physiology Heart and Circulatory Physiology, 303 (6), H703-H711. doi: 10.1152/ajpheart.00257.2011

Chen, Jing-hong, Xue, Senghai, Li, Siyuan, Wang, Zhi-lun, Yang, Haojie, Wang, Wei, Song, Daiqing, Zhou, Xiaorong and Chen, Chen (2012). Oxidant damage in Kashin-Beck disease and a rat Kashin-Beck disease model by employing T-2 toxin treatment under selenium deficient conditions. Journal of Orthopaedic Research, 30 (8), 1229-1237. doi: 10.1002/jor.22073

Huang, L., Steyn, F. J., Tan, H. Y., Xie, T. Y., Veldhuis, J. D., Ngo, S. T. and Chen, C. (2012). The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gain. Endocrinology, 153 (9), 4380-4388. doi: 10.1210/en.2012-1178

Zhang, Xinli and Chen, Chen (2012). A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy. Endocrine, 41 (3), 398-409. doi: 10.1007/s12020-012-9623-1

Tuo, Ya, Feng, Dan Dan, Wang, Deng-Feng, Sun, Jian, Li, Sheng-Bin and Chen, Chen (2012). Long-term in vitro treatment of INS-1 rat pancreatic beta-cells by unsaturated free fatty acids protects cells against gluco- and lipotoxicities via activation of GPR40 receptors. Clinical and Experimental Pharmacology and Physiology, 39 (5), 423-428. doi: 10.1111/j.1440-1681.2012.05691.x

Ma, Yi, Zhang, Lin, Edwards, Joshua N., Launikonis, Breadley S. and Chen, Chen (2012). Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. PLoS One, 7 (4) e35265, e35265.1-e35265.9. doi: 10.1371/journal.pone.0035265

Yang, Seung-Kwon, Steyn, Frederik and Chen, Chen (2012). Influence of membrane ion channel in pituitary somatotrophs by hypothalamic regulators. Cell Calcium, 51 (3-4), 231-239. doi: 10.1016/j.ceca.2011.12.005

Steyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171

Steyn, F. J., Leong, J. W., Huang, L., Tan, H. Y., Xie, T. Y., Nelson, C., Waters, M. J., Veldhuis, J. D., Epelbaum, J. and Chen, C. (2012). GH does not modulate the early fasting-induced release of free fatty acids in mice. Endocrinology, 153 (1), 273-282. doi: 10.1210/en.2011-1681

Zou, Heng, Wang, Dengfeng, Can, Xiaoling, Jiang, Long, Chen, Chen, Hu, Lina and Zhang, Yi (2011). Low TWEAK expression is correlated to the progression of squamous cervical carcinoma. Gynecologic Oncology, 123 (1), 123-128. doi: 10.1016/j.ygyno.2011.07.003

Feng, Dan D., Yang, Seung-Kwon, Loudes, Catherine, Simon, Axelle, Al-Sarraf, Tamara, Culler, Michael, Alvear-Perez, Rodrigo, Llorens-Cortes, Catherine, Chen, Chen, Epelbaum, Jacques and Gardette, Robert (2011). Ghrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons. European Journal of Neuroscience, 34 (5), 732-744. doi: 10.1111/j.1460-9568.2011.07787.x

Wang, Li, Zhao, Yufeng, Gui, Baosong, Fu, Rongguo, Ma, Feng, Yu, Jun, Qu, Ping, Dong, Lei and Chen, Chen (2011). Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+](i) increase in pancreatic islet alpha-cells. Journal of Endocrinology, 210 (2), 173-179. doi: 10.1530/JOE-11-0132

Steyn, F. J., Huang, L., Ngo, S. T., Leong, J. W., Tan, H. Y., Xie, T. Y., Parlow, A. F., Veldhuis, J. D., Waters, M. J. and Chen, C. (2011). Development of a method for the determination of pulsatile growth hormone secretion in mice. Endocrinology, 152 (8), 3165-3171. doi: 10.1210/en.2011-0253

Tuo, Ya, Wang, Dengfeng, Li, Shengbin and Chen, Chen (2011). Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways. Endocrine, 39 (2), 128-138. doi: 10.1007/s12020-010-9432-3

Han, Xuefeng, Zhu, Yunlong, Zhao, Yufeng and Chen, Chen (2011). Ghrelin reduces voltage-gated calcium currents in GH3 cells via cyclic GMP pathways. Endocrine, 40 (2), 228-236. doi: 10.1007/s12020-011-9520-z

Wang, L., Fu, Rong-Guo, Liu, Xiao-Dan, Gui, Bao-Song, Sun, Qiang, Chen, Chen, Zhao, Yu-Feng and Dong, Lei (2010). [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. Sheng li xue bao : [Acta physiologica Sinica], 62 (6), 529-534.

Fung, Jenny N. T., Seim, Inge, Wang, Dengfeng, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2010). Expression and in vitro functions of the ghrelin axis in endometrial cancer. Hormone and Cancer, 1 (5), 245-255. doi: 10.1007/s12672-010-0047-1

Sun, Qiang, Ma, Yi, Zhang, Lin, Zhao, Yu-Feng, Zang, Wei-Jin and Chen, Chen (2010). Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes. Endocrinology, 151 (9), 4446-4454. doi: 10.1210/en.2009-1432

Wang, Dengfeng, Hu, Lina, Zhang, Guonan, Zhang, Lin and Chen, Chen (2010). G protein-coupled receptor 30 in tumor development. Endocrine, 38 (1), 29-37. doi: 10.1007/s12020-010-9363-z

Wang, Dengfeng, Fung, Jenny Nga Ting Fung, Tuo, Ya, Hu, Lina and Chen, Chen (2010). TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway. Cancer Letters, 294 (1), 91-100. doi: 10.1016/j.canlet.2010.01.027

孙强 Sun, Qiang, 胡浩 Hu, Hao, 周筠 Zhou, Jun, 于小江 Yu, Xiao-jiang, 臧伟进 Zang, Wei-jin and 陈晨 Chen, Chen (2010). 肥胖抑制素对大鼠心室肌细胞收缩及L-型钙通道的影响. Xi'an Jiaotong Daxue Xuebao (Yixue Ban), 31 (4), 447-449.

Pang, Jinjiang, Xu, Qihua, Xu, Xiangbin, Yin, Hongchao, Xu, Rongkun, Guo, Shu, Hao, Wei, Wang, Luya, Chen, Chen and Cao, Ji-Min (2010). Hexarelin suppresses high lipid diet and vitamin D3-induced atherosclerosis in the rat. Peptides, 31 (4), 630-638. doi: 10.1016/j.peptides.2009.11.007

Sun, Qiang, Zang, Wei-Jin and Chen, Chen (2010). Growth hormone secretagogues reduce transient outward K+ current via phospholipase C/protein kinase C signaling pathway in rat ventricular myocytes. Endocrinology, 151 (3), 1228-1235. doi: 10.1210/en.2009-0877

Zhao, Yu-Feng, Wang, Li, Lee, Soohyun, Sun, Qiang, Tuo, Ya, Wang, Yuemin, Pei, Jianming and Chen, Chen (2010). Cholesterol induces mitochondrial dysfunction and apoptosis in mouse pancreatic beta-cell line MIN6 cells. Endocrine, 37 (1), 76-82. doi: 10.1007/s12020-009-9275-y

Chu, Kwan Yi, Cheng, Qianni, Chen, Chen, Au, Lai Shan, Seto, Sai Wang, Tuo, Ya, Motin, Leonid, Kwan, Yiu Wa and Leung, Po Sing (2010). Angiotensin II exerts glucose-dependent effects on K-v currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors. American Journal of Physiology - Cell Physiology, 298 (2), C313-C323. doi: 10.1152/ajpcell.00575.2008

Steyn, F. J., Boehme, F., Vargas, E., Wang, K., Parkington, H. C., Rao, J. R. and Chen, C. (2009). Adiponectin Regulate Growth Hormone Secretion Via Adiponectin Receptor Mediated Ca2+ Signalling in Rat Somatotrophs In Vitro. Journal of Neuroendocrinology, 21 (8), 698-704. doi: 10.1111/j.1365-2826.2009.01887.x

Chen, Chen and Sun, Qiang (2009). Discovery and research progress of ghrelin. Journal of Xi’an Jiaotong University (Medical Sciences), 30 (2), 131-136.

Yang, Seung Kwon, Wang, Kun, Parkington, Helena and Chen, Chen (2008). Involvement of tetrodotoxin-resistant Na+ current and protein kinase C in the action of growth hormone (GH)-releasing hormone on primary cultured somatotropes from GH-green fluorescent protein transgenic mice. Endocrinology, 149 (9), 4726-4735. doi: 10.1210/en.2008-0405

Zhao, Yu-Feng, Pei, Jianming and Chen, Chen (2008). Activation of ATP-sensitive potassium channels in rat pancreatic beta-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway. Journal of Endocrinology, 198 (3), 533-540. doi: 10.1677/JOE-08-0105

Wang, J., Chen, C. and Wang, R. Y. (2008). Influence of short- and long-term treadmill exercises on levels of ghrelin, obestatin and NPY in plasma and brain extraction of obese rats. Endocrine, 33 (1), 77-83. doi: 10.1007/s12020-008-9056-z

Feng, Dan Dan, Zhao, Yufeng, Luo, Zi-Qiang, Keating, Damien and Chen, Chen (2008). Linolei acid induces Ca2+ -induced inactivation of voltage dependent Ca2+ currents in rat pancreatic beta-cells. Journal of Endocrinology, 196 (2), 377-384. doi: 10.1677/JOE-07-0426

Lepore, DA, Knight, KR, Thomas, PQ and Chen Chen (2008). Generation of growth hormone expressing cells in a vascularised bioengineered microchamber. Topics in Tissue Engineering, 4, 1-16.

Keating, Damien J., Dubach, Daphne, Zanin, Mark P., Yu, Yong, Martin, Katherine, Zhao, Yu-Feng, Chen, Chen, Port, Sı´lvia, Arbone´s, Maria L., Mittaz, Laureane and Pritchard, Melanie A. (2008). DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: Implications for Down syndrome and Alzheimer's disease. Human Molecular Genetics, 17 (7), 1020-1030. doi: 10.1093/hmg/ddm374

Smart, R., Kiely, A., Beale, M., Vargas, E., Carraher, C., Kralicek, A. V., Christie, D. L., Chen, C., Newcomb, R. D. and Warr, C. G. (2008). Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins. Insect Biochemistry and Molecular Biology, 38 (8), 770-780. doi: 10.1016/j.ibmb.2008.05.002

Quan, Annie, McGeachie, Andrew B., Keating, Damien J., van Dam, Ellen M., Rusak, Jenny, Chau, Ngoc, Malladi, Chandra S., Chen, Chen, McCluskey, Adam, Cousin, Michael A. and Robinson, Phillip J. (2007). Myristyl Trimethyl Ammonium Bromide and Octadecyl Trimethyl Ammonium Bromide Are Surface-Active Small Molecule Dynamin Inhibitors that Block Endocytosis Mediated by Dynamin I or Dynamin II. Molecular Pharmacology, 72 (6), 1425-1439. doi: 10.1124/mol.107.034207

Yang, Seung-Kwon and Chen, Chen (2007). Involvement of somatostatin receptor subtypes in membrane ion channel modification by somatostatin in pituitary somatotropes. Clinical and Experimental Pharmacology and Physiology, 34 (12), 1221-1227. doi: 10.1111/j.1440-1681.2007.04806.x

Xu, Xiangbin, Pang, Jinjiang, Yin, Hongchao, Li, Meixiu, Hao, Wei, Chen, Chen and Cao, Ji-Min (2007). Hexarelin suppresses cardiac fibroblast proliferation and collagen synthesis in rat. American Journal of Physiology - Heart and Circulatory Physiology, 293 (5), 2952-2958. doi: 10.1152/ajpheart.00004.2007

Tawadros, N., Salamonsen, L. A., Dimitriadis, L. E. and Chen, C. (2007). Facilitation of decidualization by locally produced ghrelin in the human endometrium. Molecular Human Reproduction, 13 (7), 483-489. doi: 10.1093/molehr/gam029

Zhao, Y. F. and Chen, C. (2007). Regulation of pancreatic β-cell function by adipocytes. Shengli Xuebao (Acta physiologica Sinica), 59 (3), 247-252.

Yang, Seung-Kwon, Parkington, Helena C., Epelbaum, Jacques, Keating, Damien J. and Chen, Chen (2007). Somatostatin decreases voltage-gated Ca2+ currents in GH3 cells through activation of somatostatin receptor 2. American Journal of Physiology: Endocrinology and Metabolism, 292 (6), E1863-E1870. doi: 10.1152/ajpendo.00047.2007

Zhao, Yu-Feng, Feng, Dan-Dan, Hernandez, Maria and Chen, Chen (2007). 3T3-L1 adipocytes induce dysfunction of MIN6 insulin-secreting cells via multiple pathways mediated by secretory factors in a co-culture system. Endocrine, 31 (1), 52-60. doi: 10.1007/s12020-007-0001-3

Roh, Sang-Gun, Doconto, Maria, Feng, Dan Dan and Chen, Chen (2006). Differential regulation of GHRH-receptor and GHS-receptor expression by long-term in vitro treatment of ovine pituitary cells with GHRP-2 and GHRH. Endocrine, 30 (1), 55-62. doi: 10.1385/ENDO:30:1:55

Zhao, Yu-Feng, Feng, Dan Dan and Chen, Chen (2006). Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes. International Journal of Biochemistry & Cell Biology, 38 (5-6), 804-819. doi: 10.1016/j.biocel.2005.11.008

Feng, Dan Dan, Luo, Ziqiang, Roh, Sang-gun, Hernandez, Maria, Tawadros, Neveen, Keating, Damien J and Chen ,Chen (2006). Reduction in Voltage-Gated K+ Currents in Primary Cultured Rat Pancreatic ß-Cells by Linoleic Acids. Erdocrinology, 147 (2), 674-682. doi: 10.1210/en.2005-0225

Cao, Ji-Min, Ong, Huy and Chen, Chen (2006). Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system. Trends in endocrinology and metabolism, 17 (1), 13-18. doi: 10.1016/j.tem.2005.11.004

Keating, Damien J., Chen, Chen and Pritchard, Melanie A. (2006). Alzheimer's disease and endocytic dysfunction: Clues from the Down syndrome-related proteins, DSCR1 and ITSN1. Ageing research reviews, 5 (4), 388-401. doi: 10.1016/j.arr.2005.11.001

Hong, Yeon-Hee, Nishimura, Yukihiko, Hishikawa, Daisuke, Tsuzuki, Hiroaki, Miyahara, Hisae, Gotoh, Chizu, Choi, Ki-Choon, Feng, Dan Dan, Chen Chen, Lee, Hong-Gu, Katoh, Kazuo, Roh, Sang-Gun and Sasaki, Shinichi (2005). Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology, 146 (12), 5092-5099. doi: 10.1210/en.2005-0545

Feng Han, Xue, Long Zhu, Yun, Hernandez, Maria, Keating, Damien J. and Chen Chen (2005). Ghrelin reduces voltage-gated potassium currents in GH3 cells via cyclic GMP pathways. Endocrine, 28 (2), 217-224. doi: 10.1385/ENDO:28:2:217

Yang, Seung-Kwon, Parkington, Helena C., Blake, Allan D., Keating, Damien J. and Chen, Chen (2005). Somatostatin increases voltage-gated K+ currents in GH3 cells through activation of multiple somatostatin receptors. Endocrinology, 146 (11), 4975-4984. doi: 10.1210/en.2005-0696

Xu, Xiang-Bin, Pang, Jin-Jiang, Cao, Ji-Min, Ni, Chao, Xu, Rong-Kun, Yu ,Xiao-Xia, Peng, Xiao-Zhong, Yu, Xiao-Xia, Guo, Shu, Chen, Meng-Chin and Chen, Chen (2005). GH-releasing peptides improve cardiac dysfunction and cachexia and suppress stress-related hormones and cardiomyocyte apoptosis in rats with heart failure. American Journal of Physiology- Heart And Circulatory Physiology, 289 (4), H1643-H1651. doi: 10.1152/ajpheart.01042.2004

Ishiwata, H, Katoh, K, Chen, C, Yonezawa, T, Sasaki, Y and Obara, Y (2005). Suppressing actions of butyrate on growth hormone (GH) secretion induced by GH-releasing hormone in rat anterior pituitary cells. General and Comparative Endocrinology, 143 (3), 222-230. doi: 10.1016/j.ygcen.2005.03.015

Keating, Damien J and Chen, Chen (2005). Activin A stimulates catecholamine secretion from rat adrenal chromaffin cells: A new physiological mechanism. Journal of Endocrinology, 186 (2), R1-R5. doi: 10.1677/joe.1.06301

Zhao, Yu-Feng, Keating, Damien J, Hernandez, Maria, Feng, Dan Dan, Zhu, Yulong and Chen, Chen (2005). Long-term inhibition of protein tyrosine kinase impairs electrophysiologic activity and a rapid component of exocytosis in pancreatic beta cells. Journal of Molecular Endocrinology, 35 (1), 49-59. doi: 10.1677/jme.1.01779

Yan, M., Jones, M. E. E., Hernandez, M., Dongling, L, Simpson, E. R. and Chen, C. (2005). Oestrogen Replacement in Vivo Rescues the Dysfunction of Pituitary Somatotropes in Ovariectomised Aromatase Knockout Mice. Neuroendocrinology, 81 (3), 158-166. doi: 10.1159/000086864

Xue-feng, H., Yun-Long, Z. and Chen, C. (2005). Ghrelin on the role of membrane potential in GH3 cells. Journal of Rehabilitation Theory and Practice, 11, 826-829.

Katoh, K, Matsuda, A, Ishigami, A, Yonekura, S, Ishiwata, H, Chen, C and Obara, Y (2004). Suppressing effects of bisphenol A on the secretory function of ovine anterior pituitary cells. Cell Biology International, 28 (6), 463-469. doi: 10.1016/j.cellbi.2004.03.016

Zhao, Y. F., Zhu, Y. L. and Chen, C. (2004). 3T3-L1 adipocytes reduces Kir6.2 channel expression in MIN6 insulin-secreting cells in vitro. Sheng li xue bao (Acta physiologica Sinica), 56 (2), 253-257.

Pang, J., Xu, Rong-Kun, Xu, Xiang-Bin, Cao, Ji-Min, Ni, Chao, Zhu, Wen-Ling, Asotra, Kamlesh, Chen, Meng-Chin, and Chen, C. (2004). Hexarelin Protects Rat Cardiomyocytes from Angiotensin II-induced Apoptosis in Vitro. American Journal of Physiology- Heart And Circulatory Physiology, 286 (3), 1063-1069. doi: 10.1152/ajpheart.00648.2003

Yan, Ming, Jones, Margaret E. E., Hernandez, Maria, Liu, Dongling, Simpson, Evan R. and Chen Chen (2004). Functional modification of pituitary somatotropes in the aromatase knockout mouse and the effect of estrogen replacement. Endocrinology, 145 (2), 604-612. doi: 10.1210/en.2003-0646

Yan, M., Hernandez, M., Xu, R. and Chen, C. (2004). Effect of GHRH and GHRP-2 Treatment in Vitro on GH Secretion and Levels of GH, Pituitary Transcription Factor-1, GHRH-receptor, GH-secretagogue-receptor and Somatostatin Receptor mRNAs in Ovine Pituitary Cells. European Journal of Endocrinology, 150 (2), 235-242. doi: 10.1530/eje.0.1500235

Zhao, Yu-Feng, Xu, Ruwei, Hernandez, Maria, Zhu, Yunlong and Chen Chen (2003). Distinct Intracellular Ca2+ Response to Extracellular Adenosine Triphosphate in Pancreatic -Cells in Rats and Mice. Endocrine, 22 (3), 185-192. doi: 10.1385/ENDO:22:3:185

Xu, Xiang-Bin, Cao, Ji-Min, Pang, Jing-Jiang, Xu, Rong-Kun, Ni, Chao, Zhu, Wen-Ling, Asotra, Kamlesh, Chen, Meng-Chin and Chen Chen (2003). The Positive Inotropic and Calcium-Mobilizing Effects of Growth Hormone-Releasing Peptides on Rat Heart. Endocrinology, 144 (11), 5050-5057. doi: 10.1210/en.2003-0025

Chen Chen and Xu, Ruwei (2003). The in Vitro Regulation of Growth Hormone Secretion by Orexins. Endocrine, 22 (1), 57-66. doi: 10.1385/ENDO:22:1:57

Choi, Kichoon, Roh, Sang-Gun, Hong, Yeon-Hee, Shrestha, Yogendra B, Hishikawa, Daisuke, Chen Chen, Kojima, Masayasu, Kangawa, Kenji and Sasaki, Shin-Ichi (2003). The Role of Ghrelin and Growth Hormone Secretagogues Receptor on Rat Adipogenesis. Endocrinology, 144 (3), 754-759. doi: 10.1210/en.2002-220783

Xu, Ruwei, Roh, Sang-Gun, Gong, Changhong, Hernandez, Maria, Ueta, Yoichi and Chen, Chen (2002). Orexin-B Augments Voltage-Gated L-Type Ca2+ Current via Protein Kinase C-Mediated Signalling Pathway in Ovine Somatotropes.. Neuroendocrinology, 77 (3), 141-152. doi: 10.1159/000069507

Yan, Ming, Liua, Dong Ling, Chuaa, Yeow Leng, Chen, Chen and Lim, Yean Leng (2002). Tyrosine kinase inhibitors suppress α1-adrenoceptor mediated contraction in human radial, internal mammary arteries and saphenous vein. Neuroscience letters, 333 (3), 171-174. doi: 10.1016/S0304-3940(02)00877-7

Chen, Chen (2002). The Effect of Two-Day Treatment of Primary Cultured Ovine Somatotropes with GHRP-2 on Membrane Voltage-Gated K+ Currents. Endocrinology, 143 (7), 2659-2663. doi: 10.1210/en.143.7.2659

Xu, Ruwei, Wang, Qinling, Yan, Ming, Hernandez, Maria, Gong, Chang-Hong, Boon, Wah-Chin, Murata, Yoko, Ueta, Yoichi and Chen, Chen (2002). Orexin-A Augments Voltage-Gated Ca2 Currents and Synergistically Increases Growth Hormone (GH) Secretion with GH-Releasing Hormone in Primary Cultured Ovine Somatotropes. Endocrinology, 143 (12), 4609-4619. doi: 10.1210/en.2002-220506

Liu, Dong Ling, Yan, Ming, Chua, Yeow Leng, Chen, Chen and Lim, Yean Leng (2002). Effects Of Molybdenum, Silicon And Nickel On α1-Adrenoceptor-Induced Constriction Of Rat Isolated Aorta. Clinical and Experimental Pharmacology and Physiology, 29 (5-6), 395-398. doi: 10.1046/j.1440-1681.2002.03674.x

Roh, Sang-Gun, Chen, Chen, Choi, Ki-Choon, Shrestha, Yogendra and Sasaki, Shin-Ichi (2002). Is GHRH Receptor Essential to GHRP-2-Induced GH Secretion in Primary Cultured Rat Pituitary Cells?. Endocrinology, 143 (5), 1964-1967. doi: 10.1210/en.143.5.1964

Xu, Ruwei, Zhao, Yufeng and Chen, Chen (2002). Growth hormone-releasing peptide-2 reduces inward rectifying K+ currents via a PKA-cAMP-mediated signalling pathway in ovine somatotropes. The journal of physiology, 545 (2), 421-433. doi: 10.1113/jphysiol.2002.030916

Wallace, Damian J, Chen, Chen and Marley, Philip D (2002). Histamine promotes excitability in bovine adrenal chromaffin cells by inhibiting an M-current. The journal of physiology, 540 (3), 921-939. doi: 10.1113/jphysiol.2001.013370

Chen, Chen (2002). Ion channels and intracellular signalling systems involved in the action of hypothalamic GH releasing and inhibitory hormones. Fudan Lectures in Neurobiology, 18, 63-78.

Chen, Chen (2002). Discovery, progress and future of growth hormone releasing peptides. Basic medical sciences and clinics, 22, 1-5.

Roh, SG, Nie, GY, Loneragan, K, Gertler, A and Chen, C (2001). Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells. Endocrinology, 142 (12), 5167-5171. doi: 10.1210/en.142.12.5167

Yan, M, Liu, DL, Chua, YL, Chen, C and Lim, YL (2001). Effects of micromolar concentrations of manganese, copper, and zinc on alpha(1)-adrenoceptor-mediating contraction in rat aorta. Biological Trace Element Research, 82 (1-3), 159-166. doi: 10.1385/BTER:82:1-3:159

Chen, C (2001). Multiple intracellular signallings involved in regulation of ion channels by GH releasing or inhibitory hormones in pituitary somatotropes. Progress in Natural Science, 11 (3), 161-172.

Chen, Chen (2001). Multiple intracellular signallings involved in regulation of ion channels by GH releasing or inhibitory hormones in pituitary somatotropes. Progress in Natural Science, 11 (3), 170-172.

Chen, C., Roh, S. G., Nie, G. Y., Loneragan, K., Xu, R. W., Ruan, M., Clarke, I. J., Goding, J. W. and Gertler, A. (2001). The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs. Endocrine, 14 (1), 73-78.

Chen, C, Xu, RW, Clarke, IJ, Ruan, M, Loneragan, K and Roh, SG (2000). Diverse intracellular signalling systems used by growth hormone-releasing hormone in regulating voltage-gated Ca2+ or K+ channels in pituitary somatotropes. Immunology and Cell Biology, 78 (4), 356-368. doi: 10.1046/j.1440-1711.2000.00917.x

Ishiwata, H, Nagano, M, Sasaki, Y, Chen, C and Katoh, K (2000). Short-chain fatty acids inhibit the release and content of growth hormone in anterior pituitary cells of the goat. General and Comparative Endocrinology, 118 (3), 400-406. doi: 10.1006/gcen.2000.7468

Chen, C (2000). Growth hormone secretagogue actions on the pituitary gland: Multiple receptors for multiple ligands?. Clinical and Experimental Pharmacology and Physiology, 27 (5-6), 323-329. doi: 10.1046/j.1440-1681.2000.03258.x

Xu, R., Clarke, I.J., Chen, S. and Chen, C. (2000). Growth hormone-releasing hormone decreases voltage-gated potassium currents in GH4C1 cells. Journal of Neuroendocrinology, 12 (2), 147-157. doi: 10.1046/j.1365-2826.2000.00430.x

Xu, RW, Roh, SG, Loneragan, K, Pullar, M and Chen, C (1999).

Emeritus Professor Chen Chen

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