Bellingham Group - Neurobiology of motor behaviour
In the Bellingham Lab, we investigate the electrophysiology of synaptic transmission, ion currents and central pattern generation in CNS neurones
Current research focuses on the electrophysiology of central nervous system neurones using various in vitro slice preparations, patch clamp techniques, imaging, molecular biology and computer modelling.
Mechanisms of neurological disease:
- Pathogenesis and treatment of motor neuron disease in animal models
- Electrophysiology of neurotransmitter receptors and ion channels in motor neurons and other central neurons
- Developmental changes in and mechanisms of short and long term synaptic plasticity
- Neurobiology of addiction and relapse
- Neurobiology of autism
Synaptic transmission:
- Electrophysiology of neurotransmitter receptors and ion channels in motor neurons and other central neurons
- Developmental changes in and mechanisms of short and long term synaptic plasticity
Neurotransmitter receptors and ion currents in CNS neurones:
- Neurotransmitter receptor modulation of motor neurones - neuropharmacology and second messenger systems
- Effects of anaethetic agents on motor neuron excitability
Rhythmic control of movements:
- Role of glycine and GABA A receptors in programmed cell death of motor neurones and rhythmic movements
- Studies of ion currents controlling rhythm generation and computer models of single neurones and rhythmic networks
Find out more about our diverse range of research interests.