Reichelt Group - Cardiac disease and therapy

The Cardiac Disease and Therapy laboratory blends advanced physiological assessment of cardiac function with leading molecular approaches for targeted, cell-specific manipulation of gene expression to understand how the heart adapts to stress in health and disease.

We have expertise in assessment of cardiac function in whole small animals (echocardiography), isolated hearts (systolic and diastolic, vascular function, ischaemic responses) and in characterisation of cell changes (enlargement, proliferation, death) in culture that allows advanced instrumentation and development of novel assessment techniques. This expertise is blended with targeted manipulation of protein expression in a time- and cell subtype-specificities manner through in vivo and in vitro gene editing, transfection and infection. We also characterise changes in cardiac biochemistry using immunocytochemistry, and RNA/DNA/protein quantification. Integrating this broad range of expertise to experiments enables us to undertake highly integrated assessment of the heart.

Reichelt group

Group Head


  • Dr Jake Russell (Postdoc)
  • Courtney Vedelago (Research Assistant)



  • Zunhan Lu (Frances)


  • Kahli Jones
  • Maddison Sawyer
  • Hui Yi Choo (Cathy)
  • Sophie Watson
  • Monique Lowes
  • Callum Tucker
  • Agalihei Sasidarakumaaran
  • Understanding how an old heart gets stiff

ARC Discovery Project DP200101152 - 2020-2022

CIA Reichelt, CIB Headrick, CIC Thomas, PI Patel

  • How tissues generate the peptide hormone angiotensin II

ARC Discovery Project DP190102072, 2019-2021

CIA Thomas, CIB Reichelt

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