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Dr Jackson Thorp

j.thorp@uq.edu.au

Publications

Journal Articles (16)
Conference Paper (1)
Thesis (1)

Journal Articles

Woodward, Damian J., Thorp, Jackson G., Middeldorp, Christel M., Akóṣílè, Wọlé, Derks, Eske M. and Gerring, Zachary F. (2025). Leveraging pleiotropy for the improved treatment of psychiatric disorders. Molecular Psychiatry, 30 (2) 4314, 705-721. doi: 10.1038/s41380-024-02771-7
Wormington, Briar, Thorp, Jackson G., Gerring, Zachary F., Scott, James G., Akosile, Wole and Derks, Eske M. (2024). The genetic architecture of substance use and its diverse correlations with mental health traits. Psychiatry Research, 342 116200, 116200. doi: 10.1016/j.psychres.2024.116200
García-Marín, Luis M., Campos, Adrian I., Diaz-Torres, Santiago, Rabinowitz, Jill A., Ceja, Zuriel, Mitchell, Brittany L., Grasby, Katrina L., Thorp, Jackson G., Agartz, Ingrid, Alhusaini, Saud, Ames, David, Amouyel, Philippe, Andreassen, Ole A., Arfanakis, Konstantinos, Arias-Vasquez, Alejandro, Armstrong, Nicola J., Athanasiu, Lavinia, Bastin, Mark E., Beiser, Alexa S., Bennett, David A., Bis, Joshua C., Boks, Marco P. M., Boomsma, Dorret I., Brodaty, Henry, Brouwer, Rachel M., Buitelaar, Jan K., Burkhardt, Ralph, Cahn, Wiepke, Calhoun, Vince D. ... Rentería, Miguel E. (2024). Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. Nature Genetics, 56 (11), 1-12. doi: 10.1038/s41588-024-01951-z
Adams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/s0033291724001880
Woodward, Damian J., Thorp, Jackson G., Akóṣílè, Wọlé, Ong, Jue-Sheng, Gamazon, Eric R., Derks, Eske M. and Gerring, Zachary F. (2023). Identification of drug repurposing candidates for the treatment of anxiety: a genetic approach. Psychiatry Research, 326 115343, 1-11. doi: 10.1016/j.psychres.2023.115343
Thorp, Jackson G., Gerring, Zachary F., Colodro-Conde, Lucía, Byrne, Enda M., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2023). The association between trauma exposure, polygenic risk and individual depression symptoms. Psychiatry Research, 321 115101, 1-8. doi: 10.1016/j.psychres.2023.115101
Thorp, Jackson G, Mitchell, Brittany L., Gerring, Zachary F, Ong, Jue-Sheng, Gharahkhani, Puya, Derks, Eske M. and Lupton, Michelle K. (2022). Genetic evidence that the causal association of educational attainment with reduced risk of Alzheimer's disease is driven by intelligence. Neurobiology of Aging, 119, 127-135. doi: 10.1016/j.neurobiolaging.2022.07.011
Derks, Eske M., Thorp, Jackson G. and Gerring, Zachary F. (2022). Ten challenges for clinical translation in psychiatric genetics. Nature Genetics, 54 (10), 1457-1465. doi: 10.1038/s41588-022-01174-0
Aman, Asma M., García-Marín, Luis M., Thorp, Jackson G., Campos, Adrian I., Cuellar-Partida, Gabriel, Martin, Nicholas G.. and Rentería, Miguel E. (2022). Phenome-wide screening of the putative causal determinants of depression using genetic data. Human Molecular Genetics, 31 (17), 2887-2898. doi: 10.1093/hmg/ddac081
Wormington, Briar, Thorp, Jackson G., Scott, James G. and Derks, Eske M. (2022). Influences on the genetic relationship between cannabis use and schizophrenia: the role of the externalizing spectrum. Schizophrenia Bulletin, 48 (6), 1318-1326. doi: 10.1093/schbul/sbac095
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8
Mitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988
Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9
Vaissiere, James, Thorp, Jackson G., Ong, Jue-Sheng, Ortega-Alonzo, Alfredo and Derks, Eske M. (2020). Exploring phenotypic and genetic overlap between cannabis use and schizotypy. Twin Research and Human Genetics, 23 (4), 221-227. doi: 10.1017/thg.2020.68
Mitchell, Brittany L., Thorp, Jackson G., Evans, David M., Nyholt, Dale R., Martin, Nicholas G. and Lupton, Michelle K. (2020). Exploring the genetic relationship between hearing impairment and Alzheimer's disease. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 12 (1) e12108, 1-10. doi: 10.1002/dad2.12108
Thorp, Jackson G., Marees, Andries T., Ong, Jue-Sheng, An, Jiyuan, MacGregor, Stuart and Derks, Eske M. (2019). Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Psychological Medicine, 50 (14), 1-12. doi: 10.1017/s0033291719002526

Conference Paper

Thorp, Jackson G., Mitchell, Brittany L., Gerring, Zachary F., Ong, Jue‐Sheng, Gharahkhani, Puya, Derks, Eske M. and Lupton, Michelle K. (2022). Genetic evidence that the causal association of educational attainment with reduced risk of Alzheimer’s disease is driven by intelligence. Alzheimer's Association International Conference (AAIC) 2022, San Diego, CA United States, 31 July - 4 August 2022. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/alz.061144

Thesis

Thorp, Jackson Grant (2023). Embracing complexity in psychiatric genetics: investigating heterogeneity and pleiotropy in depression and major psychiatric disorders. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/6f8acc1
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