Book Chapter
Simmons, Jacinta L., Ng, Mei Fong, Neuendorf, Hannah M. and Boyle, Glen M. (2021). Anoikis resistance in melanoma. Anoikis: how the extracellular matrix regulates life-or-death decisions. (pp. 137-160) edited by Steven M. Frisch. Cham, Switzerland: Springer . doi: 10.1007/978-3-030-73856-3_7
Journal Articles
Cullen, Jason K, Yap, Pei-Yi, Ferguson, Blake, Bruce, Zara C, Koyama, Motoko, Handoko, Herlina, Hendrawan, Kevin, Simmons, Jacinta L, Brooks, Kelly M, Johns, Jenny, Wilson, Emily S, de Souza, Marjorie M A, Broit, Natasa, Stewart, Praphaporn, Shelley, Daniel, McMahon, Tracey, Ogbourne, Steven M, Nguyen, Tam Hong, Lim, Yi Chieh, Pagani, Alberto, Appendino, Giovanni, Gordon, Victoria A, Reddell, Paul W, Boyle, Glen M and Parsons, Peter G (2024). Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade. Journal for ImmunoTherapy of Cancer, 12 (4) e006602, e006602. doi: 10.1136/jitc-2022-006602
Kong, Dehui, Fahrenhorst-Jones, Tyler, Kuo, Andy, Simmons, Jacinta L., Tan, Lendl, Burns, Jed M., Pierens, Gregory K., Li, Rui, West, Nicholas P., Boyle, Glen M., Smith, Maree T., Savage, G. Paul and Williams, Craig M. (2023). seco-1-Azacubane-2-carboxylic acid: derivative scope and comparative biological evaluation. The Journal of Organic Chemistry, 89 (1), 798-803. doi: 10.1021/acs.joc.3c02333
Neuendorf, Hannah M., Simmons, Jacinta L. and Boyle, Glen M. (2023). Therapeutic targeting of anoikis resistance in cutaneous melanoma metastasis. Frontiers in Cell and Developmental Biology, 11 1183328, 1183328. doi: 10.3389/fcell.2023.1183328
Rashidieh, Behnam, Bain, Amanda Louise, Tria, Simon Manuel, Sharma, Sowmya, Stewart, Cameron Allan, Simmons, Jacinta Ley, Apaja, Pirjo M., Duijf, Pascal H. G., Finnie, John and Khanna, Kum Kum (2023). Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice. Experimental Hematology and Oncology, 12 (1) 4, 1-4. doi: 10.1186/s40164-022-00365-z
Hamilton, Karina D., Czajkowski, Daniel, Kong, Nicolas J., Tran, Trong D., Gustafson, Kirk R., Pauly, Gary, Boyle, Glen M., Simmons, Jacinta L., Steadman, Robert, Moseley, Ryan, Brooks, Peter R., Ogbourne, Steven M. and Russell, Fraser D. (2022). Anti-fibrotic potential of tomentosenol A, a constituent of cerumen from the Australian native stingless bee, Tetragonula carbonaria. Antioxidants, 11 (8) 1604, 1-15. doi: 10.3390/antiox11081604
Fane, Mitchell E., Chhabra, Yash, Spoerri, Loredana, Simmons, Jacinta L., Ludwig, Raquelle, Bonvin, Elise, Goding, Colin R., Sturm, Richard A., Boyle, Glen M., Haass, Nikolas K., Piper, Michael and Smith, Aaron G. (2022). Reciprocal regulation of BRN2 and NOTCH1/2 signaling synergistically drives melanoma cell migration and invasion. Journal of Investigative Dermatology, 142 (7), 1845-1857. doi: 10.1016/j.jid.2020.12.039
Ng, Mei Fong, Simmons, Jacinta L. and Boyle, Glen M. (2022). Heterogeneity in melanoma. Cancers, 14 (12) 3030, 1-19. doi: 10.3390/cancers14123030
Simmons, Jacinta L., Neuendorf, Hannah M. and Boyle, Glen M. (2022). BRN2 and MITF together impact AXL expression in melanoma. Experimental Dermatology, 31 (1), 89-93. doi: 10.1111/exd.14225
Cullen, Jason K., Boyle, Glen M., Yap, Pei-Yi, Elmlinger, Stefan, Simmons, Jacinta L., Broit, Natasa, Johns, Jenny, Ferguson, Blake, Maslovskaya, Lidia A., Savchenko, Andrei I., Mirzayans, Paul Malek, Porzelle, Achim, Bernhardt, Paul V., Gordon, Victoria A., Reddell, Paul W., Pagani, Alberto, Appendino, Giovanni, Parsons, Peter G. and Williams, Craig M. (2021). Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes. Scientific Reports, 11 (1) 207, 207. doi: 10.1038/s41598-020-80397-9
Pierce, Carly J., Simmons, Jacinta L., Broit, Natasa, Karunarathne, Deshapriya, Ng, Mei Fong and Boyle, Glen M. (2020). BRN2 expression increases anoikis resistance in melanoma. Oncogenesis, 9 (7) 64, 64. doi: 10.1038/s41389-020-00247-1
Cullen, Jason K., Simmons, Jacinta L., Parsons, Peter G. and Boyle, Glen M. (2020). Topical treatments for skin cancer. Advanced Drug Delivery Reviews, 153, 54-64. doi: 10.1016/j.addr.2019.11.002
Sinha, Debottam, Kalimutho, Murugan, Bowles, Josephine, Chan, Ai-Leen, Merriner, D. Jo, Bain, Amanda L., Simmons, Jacinta L., Freire, Raimundo, Lopez, J Alejandro, Hobbs, Robin M., O'Bryan, Moira K. and Khanna, Kum Kum (2018). Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. The FASEB Journal, 32 (9), 4984-4999. doi: 10.1096/fj.201701096RR
Simmons, Jacinta L., Pierce, Carly J., Al-Ejeh, Fares and Boyle, Glen M. (2017). MITF and BRN2 contribute to metastatic growth after dissemination of melanoma. Scientific Reports, 7 (1) 10909, 10909. doi: 10.1038/s41598-017-11366-y
Fane, Mitchell E., Chhabra, Yash, Hollingsworth, David E. J., Simmons, Jacinta L., Spoerri, Loredana, Oh, Tae Gyu, Chauhan, Jagat, Chin, Toby, Harris, Lachlan, Harvey, Tracey J., Muscat, George E. O., Goding, Colin R., Sturm, Richard A., Haass, Nikolas K., Boyle, Glen M., Piper, Michael and Smith, Aaron G. (2017). NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF. EBioMedicine, 16, 63-75. doi: 10.1016/j.ebiom.2017.01.013
Warren, Timothy A., Broit, Natasa, Simmons, Jacinta L., Pierce, Carly J., Chawla, Sharad, Lambie, Duncan L. J., Quagliotto, Gary, Brown, Ian S., Parsons, Peter G., Panizza, Benedict J. and Boyle, Glen M. (2016). Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process. Scientific Reports, 6 (34081) 34081, 34081. doi: 10.1038/srep34081
Simmons, Jacinta L., Pierce, Carly J. and Boyle, Glen M. (2014). Evidence for an Alternatively Spliced MITF Exon 2 Variant. Journal of Investigative Dermatology, 134 (4), 1166-1168. doi: 10.1038/jid.2013.426
Armando van der Horst, Jacinta Simmons and Kum Kum Khanna (2009). Cep55 stabilization is required for normal execution of cytokinesis. Cell Cycle, 8 (22), 3742-3749. doi: 10.4161/cc.8.22.10047
Simmons, Jacinta, Tamplin, Mark L., Jenson, Ian and Sumner, John (2008). Effect of incubation temperature on aerobic plate counts of beef and sheep carcasses. Journal of Food Protection, 71 (2), 373-375. doi: 10.4315/0362-028X-71.2.373
Conference Paper
Cullen, Jason, Yap, Pei-Yi, Ferguson, Blake, Bruce, Zara, Koyama, Motoko, Handoko, Herlina, Simmons, Jacinta, Johns, Jenny, D’Souza, Marjorie, Broit, Natasa, Stewart, Praphaporn, Shelley, Daniel, McMahon, Tracey, Ogbourne, Steven, Lim, Yi Chieh, Appendino, Giovanni, Gordon, Victoria, Reddell, Paul, Boyle, Glen and Parsons, Peter (2022). Tigilanol tiglate is a naturally occurring small molecule oncolytic that effectively ablates tumors via intratumoural injection and can enhance response to immune checkpoint blockade. SITC 37th Annual Meeting (SITC 2022), Boston, MA United States, 8-12 November 2022. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2022-sitc2022.1121
Thesis
Simmons, Jacinta Ley (2013). Understanding the roles of CEP55 and alphaB-Crystallin in oncogenesis. PhD Thesis, School of Medicine, The University of Queensland.