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Mr Tyrone Humphries

PhD student
School of Biomedical Sciences
t.humphries@uq.edu.au

Publications

Journal Articles (9)
Conference Papers (4)

Journal Articles

Urquhart, Aaron J., Glass, Christian H., Humphries, Tyrone L. R., Kassianos, Andrew J., Vesey, David A., Wood, Simon T., Gobe, Glenda C. and Ellis, Robert J. (2025). Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture. Personalized Medicine, 22 (2), 83-91. doi: 10.1080/17410541.2025.2473303
Humphries, Tyrone L. R., Lee, Soobin, Urquhart, Aaron J., Vesey, David A., Micallef, Aaron S., Winterford, Clay, Kassianos, Andrew J., Galloway, Graham J., Francis, Ross S. and Gobe, Glenda C. (2025). Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with TGF‐β1. Physiological Reports, 13 (4) e70249. doi: 10.14814/phy2.70249
Humphries, Tyrone L. R., Gobe, Glenda C., Urquhart, Aaron J., Ellis, Robert J., Galloway, Graham J., Vesey, David A. and Francis, Ross S. (2024). Identifying biochemical changes in the kidney using proton nuclear magnetic resonance in an adenine diet chronic kidney disease mouse model. NMR in Biomedicine, 37 (12) e5257, e5257. doi: 10.1002/nbm.5257
Urquhart, Aaron J., Del Vecchio, Sharon J., Lukas, Darren, Ellis, Robert J., Humphries, Tyrone L.R., Ng, Keng Lim, Samaratunga, Hemamali, Galloway, Graham J., Gobe, Glenda C., Wood, Simon T. and Mountford, Carolyn E. (2023). Isovalerylglycine and α-Ketobutyrate are novel biomarkers that discriminate clear cell renal cell carcinoma in biopsy specimens using two-dimensional magnetic resonance spectroscopy. Advances in Biomarker Sciences and Technology, 5, 68-75. doi: 10.1016/j.abst.2023.08.001
Humphries, Tyrone L.R., Vesey, David A., Galloway, Graham J., Gobe, Glenda C. and Francis, Ross S. (2023). Identifying disease progression in chronic kidney disease using proton magnetic resonance spectroscopy. Progress in Nuclear Magnetic Resonance Spectroscopy, 134-135, 52-64. doi: 10.1016/j.pnmrs.2023.04.001
Humphries, Tyrone L. R., Shen, Kunyu, Iyer, Abishek, Johnson, David W., Gobe, Glenda C., Nikolic-Paterson, David, Fairlie, David P. and Vesey, David A. (2021). PAR2-induced tissue factor synthesis by primary cultures of human kidney tubular epithelial cells is modified by glucose availability. International Journal of Molecular Sciences, 22 (14) 7532, 1-12. doi: 10.3390/ijms22147532
Iyer, Abishek, Humphries, Tyrone L. R., Owens, Evan P., Zhao, Kong-Nan, Masci, Paul P., Johnson, David W., Nikolic-Paterson, David, Gobe, Glenda C., Fairlie, David P. and Vesey, David A. (2021). PAR2 activation on human kidney tubular epithelial cells induces tissue factor synthesis, that enhances blood clotting. Frontiers in Physiology, 12 615428, 615428. doi: 10.3389/fphys.2021.615428
Humphries, Tyrone L.R., Johnson, Lambro A., Masci, Paul P., Gobe, Glenda C. and Vesey, David A. (2021). Progress curve analysis of microtitre plate plasma clotting assays. Assessment of tissue factor levels. Analytical Biochemistry, 614 114060, 114060. doi: 10.1016/j.ab.2020.114060
Owens, Evan, Tan, Ken-Soon, Ellis, Robert, Del Vecchio, Sharon, Humphries, Tyrone, Lennan, Erica, Vesey, David, Healy, Helen, Hoy, Wendy and Gobe, Glenda (2020). Development of a biomarker panel to distinguish risk of progressive chronic kidney disease. Biomedicines, 8 (12) 606, 606-16. doi: 10.3390/biomedicines8120606

Conference Papers

Humphries, Tyrone, Dong, Xin, Watson, Julia, Mountford, Carolyn, Ellis, Robert, Vesey, David, Galloway, Graham, Gobe, Glenda and Francis, Ross (2023). Evaluating kidney fibrosis using in vivo 1h magnetic resonance spectroscopy in patients with chronic kidney disease and live donors. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4–6 September 2023. Richmond, VIC Australia: John Wiley & Sons.
Humphries, Tyrone, Gobe, Glenda, Urquhart, Aaron, Vesey, David, Ellis, Robert, Galloway, Graham and Francis, Ross (2023). Changes in energy metabolism in the kidney with tubulointerstitial fibrosis: an ex vivo whole tissue 2d-cosy approach. 60th ERA Congress, Milan, Italy, 15-18 June 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ndt/gfad063c_4344
Humphries, Tyrone, Gobe, Glenda, Urquhart, Aaron, Galloway, Graham, Vesey, David and Francis, Ross (2022). Identifying biochemical changes in the kidney using nuclear magnetic resonance in an adenine-diet chronic kidney disease mouse model. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), 0nline, 17–19 October 2022. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14099
Owens, E., Hoy, W., Tan, K., Lennan, E., Cameron, A., Humphries, T., Ellis, R., Healy, H. and Gobe, G. (2020). Biomarkers that predict progression of chronic kidney disease more accurately than established clinical parameters. Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Online, 28 November - 2 December 2020. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/nep.13798
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