Associate Professor Juliet French
Honorary Associate Professor
School of Biomedical Sciences
QIMR Berghofer
Journal Articles
Rivera, Isela Sarahi, French, Juliet D., Bitar, Mainá, Sivakumaran, Haran, Nair, Sneha, Kaufmann, Susanne, Hillman, Kristine M., Moradi Marjaneh, Mahdi, Beesley, Jonathan and Edwards, Stacey L. (2024). GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers. PLOS Genetics, 20 (11) ARTN e1011490, e1011490. doi: 10.1371/journal.pgen.1011490
Wang, Lu, Bitar, Mainá, Lu, Xue, Jacquelin, Sebastien, Nair, Sneha, Sivakumaran, Haran, Hillman, Kristine M., Kaufmann, Susanne, Ziegman, Rebekah, Casciello, Francesco, Gowda, Harsha, Rosenbluh, Joseph, Edwards, Stacey L. and French, Juliet D. (2024). CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair. Molecular Cancer, 23 (1) 101. doi: 10.1186/s12943-024-02021-y
Du, Xiaofeng, McManus, Donald P., French, Juliet D., Sivakumaran, Haran, Johnston, Rebecca L., Kondrashova, Olga, Fogarty, Conor E., Jones, Malcolm K. and You, Hong (2023). Lentiviral transduction-based CRISPR/Cas9 editing of Schistosoma mansoni acetylcholinesterase. Current Genomics, 24 (3), 155-170. doi: 10.2174/1389202924666230823094608
Bitar, Mainá, Rivera, Isela Sarahi, Almeida, Isabela, Shi, Wei, Ferguson, Kaltin, Beesley, Jonathan, Lakhani, Sunil R., Edwards, Stacey L. and French, Juliet D. (2023). Redefining normal breast cell populations using long noncoding RNAs. Nucleic Acids Research, 51 (12), 6389-6410. doi: 10.1093/nar/gkad339
Tuano, Natasha K., Beesley, Jonathan, Manning, Murray, Shi, Wei, Perlaza-Jimenez, Laura, Malaver-Ortega, Luis F., Paynter, Jacob M., Black, Debra, Civitarese, Andrew, McCue, Karen, Hatzipantelis, Aaron, Hillman, Kristine, Kaufmann, Susanne, Sivakumaran, Haran, Polo, Jose M., Reddel, Roger R., Band, Vimla, French, Juliet D., Edwards, Stacey L., Powell, David R., Chenevix-Trench, Georgia and Rosenbluh, Joseph (2023). CRISPR screens identify gene targets at breast cancer risk loci. Genome Biology, 24 (1) 59, 1-23. doi: 10.1186/s13059-023-02898-w
Du, Xiaofeng, McManus, Donald P., French, Juliet D., Collinson, Natasha, Sivakumaran, Haran, MacGregor, Skye R., Fogarty, Conor E., Jones, Malcolm K. and You, Hong (2023). CRISPR interference for sequence-specific regulation of fibroblast growth factor receptor A in Schistosoma mansoni. Frontiers in Immunology, 13 1105719, 1-14. doi: 10.3389/fimmu.2022.1105719
Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann ... Fletcher, Olivia (2021). CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4), 842-854. doi: 10.1038/s41416-020-01185-w
Du, Xiaofeng, McManus, Donald P., French, Juliet D., Jones, Malcolm K. and You, Hong (2021). CRISPR/Cas9: A new tool for the study and control of helminth parasites. BioEssays, 43 (1) 2000185, 1-12. doi: 10.1002/bies.202000185
French, J. D. and Edwards, S. L. (2020). The role of noncoding variants in heritable disease. Trends in Genetics, 36 (11), 880-891. doi: 10.1016/j.tig.2020.07.004
Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Shi, Wei, Hillman, Kristine M., Kaufmann, Susanne, Hussein, Nehal, Kar, Siddhartha, Lima, Luize G., Ham, Sunyoung, Möller, Andreas, Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). eQTL Colocalization Analyses Identify NTN4 as a Candidate Breast Cancer Risk Gene. American Journal of Human Genetics, 107 (4), 778-787. doi: 10.1016/j.ajhg.2020.08.006
Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). Non-coding RNAs underlie genetic predisposition to breast cancer. Genome Biology, 21 (1) 7, 7. doi: 10.1186/s13059-019-1876-z
Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lima, Luize G., Hillman, Kristine M., Kaufmann, Susanne, Tuano, Natasha, Hussein, Nehal, Ham, Sunyoung, Mukhopadhyay, Pamela, Kazakoff, Stephen, Lee, Jason S., Michailidou, Kyriaki, Barnes, Daniel R., Antoniou, Antonis C., Fachal, Laura, Dunning, Alison M., Easton, Douglas F., Waddell, Nicola, Rosenbluh, Joseph, Möller, Andreas, Chenevix-Trench, Georgia, French, Juliet D. and Edwards, Stacey L. (2020). Chromatin interactome mapping at 139 independent breast cancer risk signals. Genome Biology, 21 (1) 8, 8. doi: 10.1186/s13059-019-1877-y
Fachal, Laura, Aschard, Hugues, Beesley, Jonathan, Barnes, Daniel R., Allen, Jamie, Kar, Siddhartha, Pooley, Karen A., Dennis, Joe, Michailidou, Kyriaki, Turman, Constance, Soucy, Penny, Lemaçon, Audrey, Lush, Michael, Tyrer, Jonathan P., Ghoussaini, Maya, Marjaneh, Mahdi Moradi, Jiang, Xia, Agata, Simona, Aittomäki, Kristiina, Alonso, M. Rosario, Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arason, Adalgeir, Arndt, Volker, Aronson, Kristan J., Arun, Banu K., Auber, Bernd, Auer, Paul L. ... Dunning, Alison M. (2020). Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52 (1), 56-73. doi: 10.1038/s41588-019-0537-1
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Homologous recombination DNA repair defects in PALB2-associated breast cancers. npj Breast Cancer, 5 (1) 23. doi: 10.1038/s41523-019-0115-9
McCabe, Mark J., Gauthier, Marie-Emilie A., Chan, Chia-Ling, Thompson, Tanya J., De Sousa, Sunita M.C., Puttick, Clare, Grady, John P., Gayevskiy, Velimir, Tao, Jiang, Ying, Kevin, Cipponi, Arcadi, Deng, Niantao, Swarbrick, Alex, Thomas, Melissa L., Lord, Reginald V., Johns, Amber L., Kohonen-Corish, Maija, O’Toole, Sandra A., Clark, Jonathan, Mueller, Simon A., Gupta, Ruta, McCormack, Ann I., Dinger, Marcel E., Cowley, Mark J., Aghmesheh, Morteza, Amor, David, Andrews, Lesley, Antill, Yoland, Armitage, Shane ... Young, Mary-Anne (2019). Development and validation of a targeted gene sequencing panel for application to disparate cancers. Scientific Reports, 9 (1) 17052, 17052. doi: 10.1038/s41598-019-52000-3
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Publisher Correction: Homologous recombination DNA repair defects in PALB2-associated breast cancers (npj Breast Cancer, (2019), 5, 1, (23), 10.1038/s41523-019-0115-9). npj Breast Cancer, 5 (1) 44. doi: 10.1038/s41523-019-0140-8
Figlioli, Gisella, Bogliolo, Massimo, Catucci, Irene, Caleca, Laura, Lasheras, Sandra Viz, Pujol, Roser, Kiiski, Johanna I., Muranen, Taru A., Barnes, Daniel R., Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K., Leslie, Goska, Aalfs, Cora M., Balleine, Rosemary, Baxter, Robert, Braye, Stephen, Carpenter, Jane, Dahlstrom, Jane, Forbes, John, Lee, C. Soon, Marsh, Deborah, Morey, Adrienne, Pathmanathan, Nirmala, Scott, Rodney, Simpson, Peter, Spigelman, Allan, Wilcken, Nicholas, Yip, Desmond ... Peterlongo, Paolo (2019). The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. npj Breast Cancer, 5 (1) 38, 38. doi: 10.1038/s41523-019-0127-5
Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C., kConFab, Sexton, Adrienne, Christian, Alice, Trainer, Alison, Spigelman, Allan, Fellows, Andrew, Shelling, Andrew, De Fazio, Anna, Blackburn, Anneke, Crook, Ashley, Meiser, Bettina, Patterson, Briony, Clarke, Christine, Saunders, Christobel, Hunt, Clare, Scott, Clare, Amor, David, Marsh, Deborah, Edkins, Edward ... Antill, Yoland (2018). Heritable DNA methylation marks associated with susceptibility to breast cancer. Nature Communications, 9 (1) 867. doi: 10.1038/s41467-018-03058-6
Milevskiy, Michael J. G., Sandhu, Gurveen K., Wronski, Anna, Korbie, Darren, Brewster, Brooke L., Shewan, Annette, Edwards, Stacey L., French, Juliet D. and Brown, Melissa A. (2018). MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer. Oncotarget, 9 (71), 33577-33588. doi: 10.18632/oncotarget.26094
Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Cowper-Sal Lari, Richard, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Børge G, Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2018). Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999)). Nature communications, 9 (1) 16193. doi: 10.1038/ncomms16193
Michailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha, Bolla, Manjeet K, Wang, Qin, Tyrer, Jonathan, Dicks, Ed, Lee, Andrew, Wang, Zhaoming, Allen, Jamie, Keeman, Renske, Eilber, Ursula, French, Juliet D, Qing Chen, Xiao, Fachal, Laura, McCue, Karen, McCart Reed, Amy E, Ghoussaini, Maya, Carroll, Jason S, Jiang, Xia, Finucane, Hilary, Adams, Marcia ... Easton, Douglas F (2017). Association analysis identifies 65 new breast cancer risk loci. Nature, 551 (7678), 92-94. doi: 10.1038/nature24284
Betts, Joshua A., Moradi Marjaneh, Mahdi, Al-Ejeh, Fares, Lim, Yi Chieh, Shi, Wei, Sivakumaran, Haran, Tropee, Romain, Patch, Ann.-Marie, Clark, Michael B., Bartonicek, Nenad, Wiegmans, Adrian P., Hillman, Kristine M., Kaufmann, Susanne, Bain, Amanda L., Gloss, Brian S., Crawford, Joanna, Kazakoff, Stephen, Wani, Shivangi, Wen Shu W., Day, Bryan, Moller, Andreas, Cloonan, Nicole, Pearson,John, Brown, Melissa A., Mercer, Timothy R., Waddell, Nicola, Khanna, Kum Kum, Dray, Eloise, Dinger, Marcel E. ... French, Juliet D. (2017). Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage. American Journal of Human Genetics, 101 (2), 255-266. doi: 10.1016/j.ajhg.2017.07.007
Powell, Joseph E., Fung, Jenny N., Shakhbazov, Konstantin, Sapkota, Yadav, Cloonan, Nicole, Hemani, Gibran, Hillman, Kristine M., Kaufmann, Susanne, Luong, Hien T., Bowdler, Lisa, Painter, Jodie N., Holdsworth-Carson, Sarah J., Visscher, Peter M., Dinger, Marcel E., Healey, Martin, Nyholt, Dale R., French, Juliet D., Edwards, Stacey L., Rogers, Peter A. W. and Montgomery, Grant W. (2016). Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339. Human Molecular Genetics, 25 (22), 5046-5058. doi: 10.1093/hmg/ddw320
Ghoussaini, Maya, French, Juliet D., Michailidou, Kyriaki, Nord, Silje, Beesley, Jonathan, Canisus, Sander, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lee, Jason S., Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Milne, Roger L., Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara ... kConFab/AOCS Investigators (2016). Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. American Journal of Human Genetics, 99 (4), 903-911. doi: 10.1016/j.ajhg.2016.07.017
Darabi, Hatef, Beesley, Jonathan, Droit, Arnaud, Kar, Siddhartha, Nord, Silje, Marjaneh, Mahdi Moradi, Soucy, Penny, Michailidou, Kyriaki, Ghoussaini, Maya, Wahl, Hanna Fues, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Alonso, M. Rosario, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Benitez, Javier, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Broeks, Annegien, Bruening, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Choi, Ji-Yeob, Conroy, Don M. ... Dunning, Alison M. (2016). Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs). Scientific Reports, 6 ARTN 32512. doi: 10.1038/srep32512
Milevskiy, Michael J. G., Al-Ejeh, Fares, Saunus, Jodi M., Northwood, Korinne S., Bailey, Peter J., Betts, Joshua A., McCart Reed, Amy E., Nephew, Kenneth P., Stone, Andrew, Gee, Julia M. W., Dowhan, Dennis H., Dray, Eloise, Shewan, Annette M., French, Juliet D., Edwards, Stacey L., Clark, Susan J., Lakhani, Sunil R. and Brown, Melissa A. (2016). Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer. Human Molecular Genetics, 25 (15), 3269-3283. doi: 10.1093/hmg/ddw177
Painter, Jodie N., Kaufmann, Susanne, O'Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B. and Edwards, Stacey L. (2016). A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding. American Journal of Human Genetics, 98 (6), 1159-1169. doi: 10.1016/j.ajhg.2016.04.012
Cheng, Timothy H. T., Thompson, Deborah J., O'Mara, Tracy A., Painter, Jodie N., Glubb, Dylan M., Flach, Susanne, Lewis, Annabelle, French, Juliet D., Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W., Nyholt, Dale R., Ahmed, Shahana, Healey, Catherine S., Shah, Mitul, Dennis, Joe, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander ... Spurdle, Amanda B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature Genetics, 48 (6), 667-674. doi: 10.1038/ng.3562
Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001
Wronski, A., Sandhu, G. K., Milevskiy, M. J., Brewster, B. L., Bridge, J. A., Shewan, A. M., Edwards, S. L., French, J. D. and Brown, M. A. (2016). MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland. Oncogenesis, 5 (4) e218, e218.1-e218.9. doi: 10.1038/oncsis.2016.27
Dunning, Alison M., Michailidou, Kyriaki, Kuchenbaecker, Karoline B., Thompson, Deborah, French, Juliet D., Beesley, Jonathan, Healey, Catherine S., Kar, Siddhartha, Pooley, Karen A., Lopez-Knowles, Elena, Dicks, Ed, Barrowdale, Daniel, Sinnott-Armstrong, Nicholas A., Sallari, Richard C., Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Marjaneh, Mahdi Moradi, Lee, Jason S., Hills, Margaret, Jarosz, Monika, Drury, Suzie, Canisius, Sander, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Hopper, John L., Southey, Melissa C., Broeks, Annegien ... Edwards, Stacey L. (2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics, 48 (4), 374-386. doi: 10.1038/ng.3521
French, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047
Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Dörk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., García-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, Dos-Santos-silva, Isabel, Sawyer, Elinor J. ... Zeps, N. (2016). RAD51B in familial breast cancer. PLoS One, 11 (5) e0153788, e0153788. doi: 10.1371/journal.pone.0153788
Painter J.N., O'Mara T.A., Batra J., Cheng T., Lose F.A., Dennis J., Michailidou K., Tyrer J.P., Ahmed S., Ferguson K., Healey C.S., Kaufmann S., Hillman K.M., Walpole C., Moya L., Pollock P., Jones A., Howarth K., Martin L., Gorman M., Hodgson S., De Polanco M.M.E., Sans M., Carracedo A., Castellvi-Bel S., Rojas-Martinez A., Santos E., Teixeira M.R., Carvajal-Carmona L. ... Spurdle A.B. (2015). Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics, 24 (5), 1478-1492. doi: 10.1093/hmg/ddu552
Stirzaker, Clare, Zotenko, Elena, Song, Jenny Z., Qu, Wenja, Nair, Shalima, Locke, Warwick J., Stone, Andrew Stone, Armstrong, Nicola J., Robinson, Mark D., Dobrovic, Alexander, Avery-Kiejda, Kelly A., Peters, Kate M., French, Juliet D., Stein, Sandra, Korbie, Darren J., Trau, Matt, Forbes, John F., Scott, Rodney J., Brown, Melissa A., Francis, Glenn D. and Clark, Susan J. (2015). Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value. Nature Communications, 6 (5899) 5899, 1-11. doi: 10.1038/ncomms6899
Glubb, Dylan, Maranian, Mel J., Michailidou, Kyriaki, Pooley, Karen A., Meyer, Kerstin, Kar, Siddhartha, Carlebur, Saskia, O'Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Canisius, Sander, Hopper, John L., Southey, Melissa C., Tsimiklis, Helen, Apicella, Carmel, Schmidt, Marjanka K., Broeks, Annegien, Hogervorst, Frans B., van der Schoot, C. Ellen, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter, Ruebner, Matthias, Ekici, Arif B., Beckmann, Matthias W. ... French, Juliet D. (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics, 96 (1), 5-20. doi: 10.1016/j.ajhg.2014.11.009
Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Lari, Richard Cowper-Sal, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Borge G., Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5 (1) 4999, 4999.1-4999.12. doi: 10.1038/ncomms5999
Meyer, Kerstin B., O'Reilly, Martin, Michailidou, Kyriaki, Carlebur, Saskia, Edwards, Stacey L., French, Juliet D., Prathalingham, Radhika, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, de Santiago, Ines, Hopper, John L., Tsimiklis, Helen, Apicella, Carmel, Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Van 't Veer, Laura J., Hogervorst, Frans B., Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter A., Lux, Michael P., Ekici, Arif B., Beckmann, Matthias W., Peto, Julian, dos Santos Silva, Isabel ... Easton, Douglas F. (2013). Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1. American Journal of Human Genetics, 93 (6), 1046-1060. doi: 10.1016/j.ajhg.2013.10.026
Edwards, Stacey L., Beesley, Jonathan, French, Juliet D. and Dunning, Alison M. (2013). Beyond GWASs: illuminating the dark road from association to function. American Journal of Human Genetics, 93 (5), 779-797. doi: 10.1016/j.ajhg.2013.10.012
French, Juliet D., Ghoussaini, Maya, Edwards, Stacey L., Meyer, Kerstin B., Michailidou, Kyriaki, Ahmed, Shahana, Khan, Sofia, Maranian, Mel J., O'Reilly, Martin, Hillman, Kristine M., Betts, Joshua A., Carro, Thomas, Bailey, Peter J., Dicks, Ed, Beesley, Jonathan, Tyrer, Jonathan, Maia, Ana-Teresa, Beck, Andrew, Knoblauch, Nicholas W., Chen, Constance, Kraft, Peter, Barnes, Daniel, Gonzalez-Neira, Anna, Rosario Alonso, M., Herrero, Daniel, Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Luccarini, Craig ... Dunning, Alison M. (2013). Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. American Journal of Human Genetics, 92 (4), 489-503. doi: 10.1016/j.ajhg.2013.01.002
Bojesen, Stig E., Pooley, Karen A., Johnatty, Sharon E., Beesley, Jonathan, Michailidou, Kyriaki, Tyrer, Jonathan P., Edwards, Stacey L., Pickett, Hilda A., Shen, Howard C., Smart, Chanel E., Hillman, Kristine M., Mai, Phuong L., Lawrenson, Kate, Stutz, Michael D., Lu, Yi, Karevan, Rod, Woods, Nicholas, Johnston, Rebecca L., French, Juliet D., Chen, Xiaoqing, Weischer, Maren, Nielsen, Sune F., Maranian, Melanie J., Ghoussaini, Maya, Ahmed, Shahana, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Dennis, Joe ... Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) (2013). Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics, 45 (4), 371-384. doi: 10.1038/ng.2566
Betts, Joshua A., French, Juliet D., Brown, Melissa A. and Edwards, Stacey L. (2012). Long-range transcriptional regulation of breast cancer genes. Genes, Chromosomes and Cancer, 52 (2), 113-125. doi: 10.1002/gcc.22020
Brewster, Brooke L., Rossiello, Francesca, French, Juliet D., Edwards, Stacey L., Wong, Ming, Wronski, Ania, Whiley, Phillip, Waddell, Nic, Chen, Xiaowei, Bove, Betsy, kConFab, Hopper, John L., John, Esther M., Andrulis, Irene, Daly, Mary, Volorio, Sara, Bernard, Loris, Peissel, Bernard, Manoukian, Siranoush, Barile, Monica, Pizzamiglio, Sara, Verderio, Paolo, Spurdle, Amanda B., Radice, Paolo, Godwin, Andrew K., Southey, Melissa C., Brown, Melissa A. and Peterlongo, Paolo (2012). Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site. Human Mutation, 33 (12), 1665-1675. doi: 10.1002/humu.22159
Smart, Chanel E., Askarian Amiri, Marjan E., Wronski, Ania, Dinger, Marcel E., Crawford, Joanna, Ovchinnikov, Dmitry A., Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Song, Sarah, Wiesner, Christiane, French, Juliet D., Dave, Richa K., da Silva, Leonard, Purdon, Amy, Andrew, Megan, Mattick, John S., Lakhani, Sunil R., Brown, Melissa A. and Kellie, Stuart (2012). Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors. PLoS One, 7 (7) e40742, e40742.1-e40742.13. doi: 10.1371/journal.pone.0040742
Peters, Kate M., Edwards, Stacey L., Nair, Shalima S., French, Juliet D., Bailey, Peter J., Salkield, Kathryn, Stein, Sandra, Wagner, Sarah, Francis, Glenn D., Clark, Susan J. and Brown, Melissa A. (2012). Androgen receptor expression predicts breast cancer survival: The role of genetic and epigenetic events. BMC Cancer, 12 (132) 132, 1-10. doi: 10.1186/1471-2407-12-132
Wee, E.J.H., Peters, K., Nair, S.S., Hulf, T., Stein, S., Wagner, S., Bailey, P., Lee, S.Y., Qu, W.J., Brewster, B., French, J.D., Dobrovic, A., Francis, G.D., Clark, S.J. and Brown, M.A. (2012). Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in adva. Oncogene, 31 (38), 4182-4195. doi: 10.1038/onc.2011.584
Askarian-Amiri, Marjan E., Crawford, Joanna, French, Juliet D., Smart, Chanel E., Smith, Martin A., Clark, Michael B., Ru, Kelin, Mercer, Tim R., Thompson, Ella R., Lakhani, Sunil R., Vargas, Ana C., Campbell, Ian G., Brown, Melissa A., Dinger, Marcel E. and Mattick, John S. (2011). SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA, 17 (5), 878-891. doi: 10.1261/rna.2528811
Smart, C.E., Wronski, A., French, J.D., Edwards, S.L., Asselin-Labat, M.L., Waddell, N., Peters, K., Brewster, B.L., Brooks, K., Simpson, K., Manning, N., Lakhani, S.R., Grimmond, S., Lindeman, G.J., Visvader, J.E. and Brown, M.A. (2011). Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. Oncogene, 30 (13), 1597-1607. doi: 10.1038/onc.2010.538
Pettigrew, C. A., French, J. D., Saunus, J. M., Edwards, S. L., Sauer, A. V., Smart, C. E., Lundstrom, H. T., Wiesner, C., Spurdle, A. B., Rothnagel, J. A. and Brown, M. A. (2010). Identification and functional analysis of novel BRCA1 transcripts, including mouse Brca1-Iris and human pseudo-BRCA1. Breast Cancer Research and Treatment, 119 (1), 239-247. doi: 10.1007/s10549-008-0256-2
Lim, Elgene, Vaillant, Francois, Wu, Di, Forrest, Natalie C., Pal, Bhupinder, Hart, Adam H., Asselin-Labat, Marie-Liesse, Gyorki, David E., Ward, Teresa, Partanen, Audrey, Feleppa, Frank, Huschtscha, Lily I., Thorne, Heather J., kConFab, Fox, Stephen B., Yan, Max, French, Juliet D., Brown, Melissa A., Smyth, Gordon K., Visvader, Jane E. and Lindemann, G. J. (2009). Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nature Medicine, 15 (8), 907-913. doi: 10.1038/nm.2000
Saunus, J., French, J.D., Edwards, S.L., Beveridge, D.J., Hatchell, E.C., Wagner, S.A., Stein, S.R., Davidson, A., Simpson, K.J., Francis, G.D., Leedman, P.J. and Brown, M.A. (2008). Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR. Cancer Research, 68 (22), 9469-9478. doi: 10.1158/0008-5472.CAN-08-1159
Smart, Chanel E., Clarke, Catherine, Brooks, Kelly M., Raghavendra, Ashwini, Brewster, Brooke L., French, Juliet D., Hetherington, Rehan, Fleming, Jean S., Rothnagel, Joseph A., Wainwright, Brandon, Lakhani, Sunil R. and Brown, Melissa A. (2008). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Breast Cancer Research and Treatment, 112 (2), 237-241. doi: 10.1007/s10549-007-9859-2
Tan-Wong, Sue Mei, French, Juliet D., Proudfoot, Nicholas J. and Brown, Melissa A. (2008). Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene. Proceedings of the National Academy of Sciences of the United States of America, 105 (13), 5160-5165. doi: 10.1073/pnas.0801048105
French, J.D. and Brown, M.A. (2008). Breast cancer type 1 susceptibility protein. CurrentBioData
Lovelock, Paul K., Wong, Ee Ming, Sprung, Carl N., Marsh, Anna, Hobson, Karen, French, Juliet D., Southey, Melissa, kConFab Investigators, Sculley, Tom, Pandeya, Nirmala, Brown, Melissa A., Chenevix-Trench, Georgia, Spurdle, Amanda B. and McKay, Michael J. (2007). Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability. Breast Cancer Research and Treatment, 104 (3), 257-266. doi: 10.1007/s10549-006-9415-5
Saunus, Jodi M., Edwards, Stacey L., French, Juliet D., Smart, Chanel E. and Brown, Melissa A. (2007). Regulation of BRCA1 messenger RNA stability in human epithelial cell lines and during cell cycle progression. FEBS Letters, 581 (18), 3435-3442. doi: 10.1016/j.febslet.2007.06.046
French, Juliet D., Dunn, Jasmyn, Smart, Chanel E., Manning, Nathan and Brown, Melissa A. (2006). Disruption of BRCA I function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines. Genes Chromosomes and Cancer, 45 (3), 277-289. doi: 10.1002/gcc.20290
French, J., Stirling, R., Walsh, M. and Kennedy, H. D. (2002). The expression of Ras-GTPase activating protein SH3 domain-binding proteins, G3BPs, in human breast cancers. Histochemical Journal, 34 (5), 223-231. doi: 10.1023/A:1021737413055
Kennedy, D., French, J., Guitard, E., Ru, K. L., Tocque, B. and Mattick, J. (2002). Characterization of G3BPs: Tissue specific expression, chromosomal localisation and rasGAP(120) binding studies. Journal of Cellular Biochemistry, 84 (1), 173-187. doi: 10.1002/jcb.1277
Conference Papers
Brown, M. A., French, J. D., Edwards, S. L., Peters, K. M., Wronski, A., Smart, C. E., Brewster, B. L., Wee, J. E., Waddell, N. and Francis, G. D. (2010). Identification of novel biomarkers for breast cancer, including brca1-associated breast cancer. IMPAKT Breast Cancer Conference 2010, Brussels, Belgium, MAY 06-08, 2010. Oxford, England, U.K.: Oxford University Press. doi: 10.1093/annonc/mdq145
French, J. D., Tan-Wong, S. M., Edwards, S., Smart, C. E., Proudfoot, N. J. and Brown, M. A. (2008). Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene. Fifth European Gordon Research Conference on Mammary Gland Biology, Lucca (Barga), Italy, 1-6 June 2008.
French, J. D., Edwards, S. L., Saunus, J. M., Tan-Wong, S. M., Brewster, B., Hardie, K. M., Leedman, P. J., Proudfoot, N. J. and Brown, M. A. (2008). Identification of functional regulatory elements in the non-coding regions of the BRCA1 gene. kConFab Familial Breast Cancer conference 2008, Couran Cove, Queensland, 2008.
Brewster, B., Brown, M. A., Edwards, S. L., French, J. D., Leedman, P., Proudfoot, N. J., Saunus, J. M., Southey, M., Tavtigian, S and Wong, S. M. (2007). Identification of novel mutation targets in the breast cancer susceptibility gene BRCA1 and genes that encode regulators of BRCA1. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.
French, J. D., Wong, S. M., Saunus, J. M., Smart, C. E., Proudfoot, N. J. and Brown, M. A. (2007). Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene. Australian Breast Cancer Conference 2007, Melbourne, Australia, 19-20 November 2007.
Brewster, Brooke, Brooks, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Gordon Research Conference: Mammary Gland Biology, Newport, RI, 10-15 June 2007.
Smart, C. E., Clarke, C., Brooks, K. M., Raghavendra, A., Brewster, B. L., French, J. D., Hetherington, R., Fleming, J. S., Rothnagel, J. A., Wainwright, B., Lakhani, S. R. and Brown, M. A. (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Australian Breast Cancer Conference, Melbourne, Australia, 2007.
Brewster, Brooke, Brooke, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.
Saunus, Jodi M., French, Juliet D., Edwards, Stacey L., Beveridge, Dianne J., Hatchell, Esme C., Wagner, Sarah A., Gason, Alexandra A., Simpson, Kaylene J., Leedman, Peter J. and Brown, Melissa A. (2006). Identification of RNA-binding proteins that regulate BRCA1 expression. Familial Cancer 2006: Research and Practice. A combined meeting of kConFab, Australian Ovarian Cancer Study (AOCS) and the Family Cancer Clinics of Australia and New Zealand, Couran Cove, South Stradbroke Island, Queensland, Australia, 16-19 August 2006. Kathleen Cuningham Foundation Consortium (kConFab).
Saunus, Jodi M., Wardrop, Stacey L., French, Juliet D., Beveridge, Dianne J., Hatchell, Esme C., Dinnis, Diane M., Gason, Alexandra A., Simpson, Kaylene J., Leedman, Peter J. and Brown, Melissa A. (2006). Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R. ComBio 2006, Brisbane, Queensland, Australia, 24-28 September, 2006.
Brown, M. A., Chenevix-Trench, G., French, J. D., Hobson, K., KConFab Investigators, Lovelock, P. K., Marsh, A., McKay, M., Pandeya, N., Sculley, T., Southey, M. C., Sprung, C. N., Spurdle, A. B. and Wong, E. M. (2005). Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell line phenotypic variability. Familial Cancer 2005: Research and Practice, Couran Cove, 30 August - 3 September, 2005.
French, J. D., Saunus, J. M., Wardrop, S. L. and Brown, M. A. (2005). Regulation of BRCA1 by Heregulin. Familial Cancer 2005: Research and Practice, Couran Cove, 30 Aug - 3 Sept, 2005.
Wardrop, S. L., Saunus, J. M., French, J. D., Leedman, P. J. and Brown, M. A. (2005). Transcriptional and post-transcriptional regulation of the breast cancer susceptibility gene 1 (BRCA1). National Cancer Research Institute Conference, Birmingham, UK, 2-5 Oct, 2005.
Saunus, J. M., Wardrop, S. L., French, J. D., Beveridge, D. J., Hatchell, E. C., Gason, A. A., Simpson, K.J., Leedman, P. J. and Brown, M. A. (2005). Hur post-transcriptionally regulates BRCA1: involvement of elements in the BRCA1 3' untranslated region. Molecular Approaches to Controlling Cancer, New York, 3-5 June, 2005.
Jawerth, J., French, J., Lopez, J. A., Turtle, C. J., Hart, D.J. N. and Kennedy, D. (2002). G3BP and Breast Cancer Immunotherapy. International Symposium on Recent Trends in Inflammation Research, Yeugnam University, Korea, 2002.
French, J., Manning, N.W., Robinson, S. E., Karunaratne, S. M., Reddel, R. and Brown, M. A. (2002). Investigating a role for BRCA1 in telomere maintenance. Australian Telomere Workshop, Sydney, Australia, 2002. Kent Town, South Australia:
Kennedy, H. D., French, J., Verhagen, A. and Mattick, J. S. (1999). The ras-GTPase-Activating protein SH3-Domain-binding family of proteins (G3BPs):Implications in ras-GAP120 signalling to RNA-stability and cancer progression. ComBio 99, Conrad Jupiters, Gold Coast, 27th - 30th September, 1999. Kent Town, SA: Aust. Society for Biochemistry & Molecular Biology.
Generic Document
French, J. D. and Brown, M. A. (2007). An invited review for Targeted Proteins Database. Current Biodata.
Thesis
French, Juliet Danielle (2003). Characterisation of the G3BP family of proteins. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland. doi: 10.14264/106643