Journal Articles
Cuní-López, Carla, Stewart, Romal, Quek, Hazel and White, Anthony R. (2022). Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases. Cells, 11 (10), 1662. doi: 10.3390/cells11101662
Quek, Hazel, Cuní-López, Carla, Stewart, Romal, Colletti, Tiziana, Notaro, Antonietta, Nguyen, Tam Hong, Sun, Yifan, Guo, Christine C., Lupton, Michelle K., Roberts, Tara L., Lim, Yi Chieh, Oikari, Lotta E., La Bella, Vincenzo and White, Anthony R. (2022). ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression. Journal of Neuroinflammation, 19 (1) 58. doi: 10.1186/s12974-022-02421-1
Aguilar-Morante, Diana, Gómez-Cabello, Daniel, Quek, Hazel, Liu, Tianqing, Hamerlik, Petra and Lim, Yi Chieh (2022). Therapeutic opportunities of disrupting genome integrity in adult diffuse glioma. Biomedicines, 10 (2) 332. doi: 10.3390/biomedicines10020332
Nikesitch, Nicholas, Rebeiro, Patricia, Ho, Lye Lin, Pothula, Srinivasa, Wang, Xin Maggie, Khong, Tiffany, Quek, Hazel, Spencer, Andrew, Lee, Cheok Soon, Roberts, Tara L. and Ling, Silvia C. W. (2021). The role of chaperone-mediated autophagy in bortezomib resistant multiple myeloma. Cells, 10 (12) 3464. doi: 10.3390/cells10123464
Milligan Armstrong, Ayeisha, Porter, Tenielle, Quek, Hazel, White, Anthony, Haynes, John, Jackaman, Connie, Villemagne, Victor, Munyard, Kylie, Laws, Simon M., Verdile, Giuseppe and Groth, David (2021). Chronic stress and Alzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia. Biological Reviews, 96 (5) brv.12750, 2209-2228. doi: 10.1111/brv.12750
Xiao, Lin, Somers, Klaartje, Murray, Jayne, Pandher, Ruby, Karsa, Mawar, Ronca, Emma, Bongers, Angelika, Terry, Rachael, Ehteda, Anahid, Gamble, Laura D., Issaeva, Natalia, Leonova, Katerina I., O'Connor, Aisling, Mayoh, Chelsea, Venkat, Pooja, Quek, Hazel, Brand, Jennifer, Kusuma, Frances K., Pettitt, Jessica A., Mosmann, Erin, Kearns, Adam, Eden, Georgina, Alfred, Stephanie, Allan, Sophie, Zhai, Lei, Kamili, Alvin, Gifford, Andrew J., Carter, Daniel R., Henderson, Michelle J. ... Haber, Michelle (2021). Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma. Clinical Cancer Research, 27 (15), 4338-4352. doi: 10.1158/1078-0432.ccr-20-2357
Lai, Hui-Chi, James, Alexander, Luff, John, De Souza, Paul, Quek, Hazel, Ho, Uda, Lavin, Martin F. and Roberts, Tara L. (2020). Regulation of RNA degradation pathways during the lipopolysaccharide response in macrophages. Journal of Leukocyte Biology, 109 (3) JLB.2AB0420-151RR, 593-603. doi: 10.1002/JLB.2AB0420-151RR
Oikari, Lotta E., Pandit, Rucha, Stewart, Romal, Cuní-López, Carla, Quek, Hazel, Sutharsan, Ratneswary, Rantanen, Laura M., Oksanen, Minna, Lehtonen, Sarka, de Boer, Carmela Maria, Polo, Jose M., Götz, Jürgen, Koistinaho, Jari and White, Anthony R. (2020). Altered brain endothelial cell phenotype from a familial alzheimer mutation and its potential implications for amyloid clearance and drug delivery. Stem Cell Reports, 14 (5), 924-939. doi: 10.1016/j.stemcr.2020.03.011
Lim, Yi Chieh, Ensbey, Kathleen S., Offenhäuser, Carolin, D'souza, Rochelle C. J., Cullen, Jason K., Stringer, Brett W., Quek, Hazel, Bruce, Zara C., Kijas, Amanda, Cianfanelli, Valentina, Mahboubi, Bijan, Smith, Fiona, Jeffree, Rosalind L., Wiesmüeller, Lisa, Wiegmans, Adrian P., Bain, Amanda, Lombard, Fanny J., Roberts, Tara L., Khanna, Kum Kum, Lavin, Martin F., Kim, Baek, Hamerlik, Petra, Johns, Terrance G., Coster, Mark J., Boyd, Andrew W. and Day, Bryan W. (2020). Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore. Neuro-Oncology, 22 (2), 216-228. doi: 10.1093/neuonc/noz159
Ho, Uda, Luff, John, James, Alexander, Lee, Cheok Soon, Quek, Hazel, Lai, Hui-Chi, Apte, Simon, Lim, Yi Chieh, Lavin, Martin F. and Roberts, Tara L. (2019). SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. Journal of Cellular and Molecular Medicine, 23 (12) jcmm.14685, 8151-8160. doi: 10.1111/jcmm.14685
Choo, Xin Yi, Liddell, Jeffrey R., Huuskonen, Mikko T., Grubman, Alexandra, Moujalled, Diane, Roberts, Jessica, Kysenius, Kai, Patten, Lauren, Quek, Hazel, Oikari, Lotta E., Duncan, Clare, James, Simon A., McInnes, Lachlan E., Hayne, David J., Donnelly, Paul S., Pollari, Eveliina, Vähätalo, Suvi, Lejavová, Katarína, Kettunen, Mikko I., Malm, Tarja, Koistinaho, Jari, White, Anthony R. and Kanninen, Katja M. (2018). Cu(atsm) Attenuates Neuroinflammation. Frontiers in Neuroscience, 12 (SEP) 668. doi: 10.3389/fnins.2018.00668
Lim, Yi Chieh, Quek, Hazel, Offenhäuser, Carolin, Fazry, Shazrul, Boyd, Andrew, Lavin, Martin, Roberts, Tara and Day, Bryan (2018). ATM inhibition prevents interleukin-6 from contributing to the proliferation of glioblastoma cells after ionizing radiation. Journal of Neuro-Oncology, 138 (3), 509-518. doi: 10.1007/s11060-018-2838-0
Quek, Hazel, Lim, Yi Chieh, Lavin, Martin F and Roberts, Tara L (2018). PIKKing a way to regulate inflammation. Immunology and Cell Biology, 96 (1), 8-20. doi: 10.1111/imcb.1001
Khameneh, Hanif Javanmard, Ho, Adrian W S, Spreafico, Roberto, Derks, Heidi, Quek, Hazel Q Y and Mortellaro, Alessandra (2017). The Syk-NFAT-IL-2 pathway in dendritic cells is required for optimal sterile immunity elicited by alum adjuvants. Journal of Immunology, 198 (1), 196-204. doi: 10.4049/jimmunol.1600420
Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. Journal of Leukocyte Biology, 101 (4), 927-947. doi: 10.1189/jlb.4VMA0716-316R
Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. Human Molecular Genetics, 26 (1), 109-123. doi: 10.1093/hmg/ddw371
Conference Papers
James, A., Luff, J., Ho, U., Quek, H., Lavin, M. and Roberts, T. (2016). SMG1 is a regulator of toll-like receptor responses. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016.
Quek, H., Luff, J., Cheung, K., Kozlov, S., Gatei, M., Lee, C. S., Bellingham, M., Noakes, P., Lim, Y. C., Barnett, N., Dingwall, S., Wolvetang, E., Mashimo, T., Roberts, T. and Lavin, M. (2016). Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200
Roberts, Tara L., Ho, Uda, Luff, John, James, Alex, Apte, Simon, Quek, Hazel and Lavin, Martin F. (2015). The roles of SMG1 and ATM in stress responses, inflammation and blood cancers. *, *, *. ATHENS: SPANDIDOS PUBL LTD.
Reberio, Patricia, James, Alexander, Ling, Silvia, Lee, C. Soon, Ho, Uda, Luff, John, Quek, Hazel, Lavin, Martin and Roberts, Tara (2015). ATM and SMG1 are tumour suppressors which co- regulate blood cancer development and cellular responses to DNA damage and oxidative stress. XVI International Workshop on ChronicLymphocytic Leukemia 2015, Sydney, Australia, 6–9 September 2015. United Kingdom: Taylor & Francis. doi: 10.3109/10428194.2015.1080893
Thesis
Quek, Hazel (2016). The Employment of Rat Models to Understand Neurodegeneration in Ataxia- Telangiectasia. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.940