Book Chapter
Foster, Simon R. and Bräuner-Osborne, Hans (2018). Investigating internalization and intracellular trafficking of GPCRs: New techniques and real-time experimental approaches. Targeting trafficking in drug development. (pp. 41-61) edited by Alfredo Ulloa-Aguirre and Ya-Xiong Tao. Cham, Switzerland: Springer. doi: 10.1007/164_2017_57
Journal Articles
Foster, Simon R. and Hudson, James E. (2024). Endothelial cells as paracrine mediators of long COVID. Nature Cardiovascular Research, 3 (10), 1181-1183. doi: 10.1038/s44161-024-00551-8
Bloxham, Conor J., Hulme, Katina D., Fierro, Fabrizio, Fercher, Christian, Pegg, Cassandra L., O'Brien, Shannon L., Foster, Simon R., Short, Kirsty R., Furness, Sebastian G. B., Reichelt, Melissa E., Niv, Masha Y. and Thomas, Walter G. (2024). Cardiac human bitter taste receptors contain naturally occurring variants that alter function. Biochemical Pharmacology, 219 115932, 115932. doi: 10.1016/j.bcp.2023.115932
Pallareti, Lisa, Rath, Tine F., Trapkov, Boris, Tsonkov, Tsonko, Nielsen, Anders Thorup, Harpsøe, Kasper, Gentry, Patrick R., Bräuner-Osborne, Hans, Gloriam, David E. and Foster, Simon R. (2023). Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139. European Journal of Pharmacology, 943 175553, 1-11. doi: 10.1016/j.ejphar.2023.175553
Pokhrel, Rina, Morgan, Alexandra, Robinson, Harley, Stone, Martin J. and Foster, Simon R. (2023). Unravelling GPCR signalling networks using global phosphoproteomics. British Journal of Pharmacology, 181 (14), 2359-2370. doi: 10.1111/bph.16052
Bhusal, Ram Prasad, Aryal, Pramod, Devkota, Shankar Raj, Pokhrel, Rina, Gunzburg, Menachem J., Foster, Simon R., Lim, Herman D., Payne, Richard J., Wilce, Matthew C. J. and Stone, Martin J. (2022). Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases. Proceedings of the National Academy of Sciences, 119 (9) e2122105119. doi: 10.1073/pnas.2122105119
Wang, Siyao, Foster, Simon R., Sanchez, Julie, Corcilius, Leo, Larance, Mark, Canals, Meritxell, Stone, Martin J. and Payne, Richard J. (2021). Glycosylation regulates N-terminal proteolysis and activity of the chemokine CCL14. ACS Chemical Biology, 16 (6), 973-981. doi: 10.1021/acschembio.1c00006
Arsova, Angela, Møller, Thor C., Hellyer, Shane D., Vedel, Line, Foster, Simon R., Hansen, Jakob L., Braüner-Osborne, Hans and Gregory, Karen J. (2021). Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias. Molecular Pharmacology, 99 (5), 328-341. doi: 10.1124/MOLPHARM.120.000185
Mills, Richard J., Humphrey, Sean J., Fortuna, Patrick R. J., Lor, Mary, Foster, Simon R., Quaife-Ryan, Gregory A., Johnston, Rebecca L., Dumenil, Troy, Bishop, Cameron, Rudraraju, Rajeev, Rawle, Daniel J., Le, Thuy, Zhao, Wei, Lee, Leo, Mackenzie-Kludas, Charley, Mehdiabadi, Neda R., Halliday, Christopher, Gilham, Dean, Fu, Li, Nicholls, Stephen J., Johansson, Jan, Sweeney, Michael, Wong, Norman C. W., Kulikowski, Ewelina, Sokolowski, Kamil A., Tse, Brian W. C., Devilée, Lynn, Voges, Holly K., Reynolds, Liam T. ... Hudson, James E. (2021). BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection. Cell, 184 (8), 2167-2182.e22. doi: 10.1016/j.cell.2021.03.026
Arsova, Angela, Møller, Thor C., Vedel, Line, Hansen, Jakob Lerche, Foster, Simon R., Gregory, Karen J. and Braüner-Osborne, Hans (2020). Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5. Molecular Pharmacology, 98 (1), 49-60. doi: 10.1124/mol.119.119032
Franck, Charlotte, Foster, Simon R., Johansen-Leete, Jason, Chowdhury, Sayeeda, Cielesh, Michelle, Bhusal, Ram Prasad, Mackay, Joel P., Larance, Mark, Stone, Martin J. and Payne, Richard J. (2020). Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition. Proceedings of the National Academy of Sciences, 117 (23), 12657-12664. doi: 10.1073/pnas.2000605117
Johansen-Leete, Jason, Passioura, Toby, Foster, Simon R., Bhusal, Ram Prasad, Ford, Daniel J., Liu, Minglong, Jongkees, Seino A. K., Suga, Hiroaki, Stone, Martin J. and Payne, Richard J. (2020). Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display. Journal of the American Chemical Society, 142 (20), 9141-9146. doi: 10.1021/jacs.0c03152
Bloxham, Conor J., Foster, Simon R. and Thomas, Walter G. (2020). A bitter taste in your heart. Frontiers in Physiology, 11 431, 431. doi: 10.3389/fphys.2020.00431
Huang, Cheng, Foster, Simon R., Shah, Anup D., Kleifeld, Oded, Canals, Meritxell, Schittenhelm, Ralf B. and Stone, Martin J. (2020). Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2. Journal of Biological Chemistry, 295 (19), 6518-6531. doi: 10.1074/jbc.RA119.012026
Hauser, Alexander S., Gloriam, David E., Bräuner-Osborne, Hans and Foster, Simon R. (2020). Novel approaches leading towards peptide GPCR de-orphanisation. British Journal of Pharmacology, 177 (5), 961-968. doi: 10.1111/bph.14950
Bhusal, Ram Prasad, Foster, Simon R. and Stone, Martin J. (2020). Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses. Protein Science, 29 (2), 420-432. doi: 10.1002/pro.3744
Foster, Simon R., Hauser, Alexander S., Vedel, Line, Strachan, Ryan T., Huang, Xi-Ping, Gavin, Ariana C., Shah, Sushrut D., Nayak, Ajay P., Haugaard-Kedström, Linda M., Penn, Raymond B., Roth, Bryan L., Bräuner-Osborne, Hans and Gloriam, David E. (2019). Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors. Cell, 179 (4), 895-908.e21. doi: 10.1016/j.cell.2019.10.010
Mos, Iris, Jacobsen, Stine E., Foster, Simon R. and Bräuner-Osborne, Hans (2019). Calcium-sensing receptor internalization is β-arrestin–dependent and modulated by allosteric ligands. Molecular Pharmacology, 96 (4), 463-474. doi: 10.1124/mol.119.116772
See Hoe, Louise E., Foster, Simon R., Wendt, Lauren, Patel, Hemal H., Headrick, John P. and Peart, Jason N. (2019). Regulation of the β-adrenergic receptor signaling pathway in sustained ligand-activated preconditioning. Journal of Pharmacology and Experimental Therapeutics, 369 (1), 37-46. doi: 10.1124/jpet.118.251660
Nøhr, Anne Cathrine, Shehata, Mohamed A., Palmer, Daniel, Pokhrel, Rina, Vallianou, Maria, Foster, Simon R., Gentry, Patrick R., Gloriam, David E. and Bräuner-Osborne, Hans (2019). Identification of a novel scaffold for a small molecule GPR139 receptor agonist. Scientific Reports, 9 (1) 3802, 3802. doi: 10.1038/s41598-019-40085-9
Roura, Eugeni and Foster, Simon R (2017). Nutrient-Sensing Biology in Mammals and Birds. Annual review of animal biosciences, 6 (1), 197-225. doi: 10.1146/annurev-animal-030117-014740
Roura, Eugeni, Foster, Simon, Winklebach, Anja, Navarro, Marta, Thomas, Walter, Campbell, Katrina and Stowasser, Michael (2016). Taste and hypertension in humans: targeting cardiovascular disease. Current Pharmaceutical Design, 22 (15), 2290-2305. doi: 10.2174/1381612822666160216151545
Donovan, Chantal, Bailey, Simon R., Tran, Jenny, Haitsma, Gertruud, Ibrahim, Zaridatul A., Foster, Simon R., Tang, Mimi L. K., Royce, Simon G. and Bourke, Jane E. (2015). Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease. American Journal of Physiology-Lung Cellular and Molecular Physiology, 309 (10), L1219-L1228. doi: 10.1152/ajplung.00156.2015
Roura, Eugeni, Aldayyani, Asya, Thavaraj, Pridhuvi, Prakash, Sangeeta, Greenway, Delma, Thomas, Walter G., Meyerhof, Wolfgang, Roudnitzky, Natacha and Foster, Simon R. (2015). Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activation. Chemical Senses, 40 (6), 427-435. doi: 10.1093/chemse/bjv024
Foster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, Dos Remedios, Cristobal G., Thomas, Walter G. and Ramialison, Mirana (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10) 1118, 1009-1027. doi: 10.1007/s00210-015-1118-1
Foster, Simon R, Roura, Eugeni, Molenaar, Peter and Thomas, Walter G. (2015). G protein-coupled receptors in cardiac biology: old and new receptors. Biophysical Reviews, 7 (1), 77-89. doi: 10.1007/s12551-014-0154-2
Foster, Simon R., Blank, Kristina, See Hoe, Louise E., Behrens, Maik, Meyerhof, Wolfgang, Peart, Jason N. and Thomas, Walter G. (2014). Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart. FASEB Journal, 28 (10), 4497-4508. doi: 10.1096/fj.14-256305
Foster, Simon R., Roura, Eugeni and Thomas, Walter G. (2014). Extrasensory perception: odorant and taste receptors beyond the nose and mouth. Pharmacology and Therapeutics, 142 (1), 41-61. doi: 10.1016/j.pharmthera.2013.11.004
James, Gregory, Foster, Simon R., Key, Brian and Beverdam, Annemiek (2013). The expression pattern of EVA1C, a novel slit receptor, is consistent with an axon guidance role in the mouse nervous system. PLoS One, 8 (9) e74115, 1-10. doi: 10.1371/journal.pone.0074115
Foster, Simon R., Porrello, Enzo R., Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D., Moritz, Karen M., Simmons, David G., Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang and Thomas, Walter G. (2013). Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart. PLoS ONE, 8 (5) e64579, e64579-1-e64579-10. doi: 10.1371/journal.pone.0064579
Bourke, J. E., Li, X., Foster, S. R., Wee, E., Dagher, H., Ziogas, J., Harris, T., Bonacci, J. V. and Stewart, A. G. (2011). Collagen remodelling by airway smooth muscle is resistant to steroids and β2-agonists. European Respiratory Journal, 37 (1), 173-182. doi: 10.1183/09031936.00008109
Conference Papers
Foster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, dos Remedios, Cris G., Thomas, Walter G. and Ramialison, Mirana (2015). Transcriptional Regulation of Taste Receptor Genes: Novel Insights From In Silico and Cardiac Gene Expression Analyses. 15th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS), Brisbane, QLD Australia, 03-05 December 2014. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/chemse/bjv008
Ward, J. E., Tran, J., Foster, S. R., Royce, S. G., Tang, M. L. and Bailey, S. R. (2009). Bronchodilator Actions of Rosiglitazone in Isolated Mouse Trachea Are PPAR gamma-Independent. NEW YORK: AMER THORACIC SOC.
Thesis
Foster, Simon R. (2013). Odorant and taste receptor systems in the heart: investigation of novel cardiac biology. PhD Thesis, School of Biomedical Sciences, The University of Queensland.