Honorary Professor James Hudson
Honorary Professor
School of Biomedical Sciences
QIMR Berghofer
Book Chapters
Mills, Richard J., Voges, Holly K., Porrello, Enzo R. and Hudson, James E. (2017). Cryoinjury model for tissue injury and repair in bioengineered human striated muscle. In Skeletal Muscle Development (pp. 209-224) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7283-8_15
Hudson, James E., Christalla, Peter and Zimmermann, Wolfram-Hubertus (2013). Pluripotent Stem Cell-Derived Cardiomyocytes for Industrial and Clinical Applications. Modern Biopharmaceuticals: Recent Success Stories. (pp. 57-76) Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527669417.ch3
Journal Articles
Hunter, Christopher R. and Hudson, James E. (2025). Macrophage Containing Cardiac Organoids for Studying Inflammatory Programmes Driving Cardiovascular Disease. Current Cardiology Reports, 27 (1) 97. doi: 10.1007/s11886-025-02246-3
Laskary, Andrew R., Hudson, James E. and Porrello, Enzo R. (2025). Designing multicellular cardiac tissue engineering technologies for clinical translation. Seminars in Cell & Developmental Biology, 171 103612, 103612. doi: 10.1016/j.semcdb.2025.103612
Pocock, Mark W., Reid, Janice D., Robinson, Harley R., Charitakis, Natalie, Krycer, James R., Foster, Simon R., Fitzsimmons, Rebecca L., Lor, Mary, Devilée, Lynn A. C., Batho, Christopher A. P., Tuano, Natasha, Howden, Sara E., Vlahos, Katerina, Watt, Kevin I., Piers, Adam T., Bibby, Kaitlyn, McNamara, James W., Sutton, Rebecca, Iaprintsev, Valerii, Mathew, Jacob, Voges, Holly K., Fortuna, Patrick R. J., Bass-Stringer, Sebastian, Vivien, Celine, Rae, James, Parton, Robert G., Firulli, Anthony B., Lisowski, Leszek, Huckstep, Hannah ... Hudson, James E. (2025). Maturation of human cardiac organoids enables complex disease modeling and drug discovery. Nature Cardiovascular Research, 1-20. doi: 10.1038/s44161-025-00669-3
Meizoso-Huesca, Aldo, Lamboley, Cedric R., Krycer, James R., Hodson, Mark P., Hudson, James E. and Launikonis, Bradley S. (2025). Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression. Nature Communications, 16 (1) 3056, 3056. doi: 10.1038/s41467-025-58393-2
Krycer, James R., Plan, Manuel, Stoll, Thomas, Laskary, Andrew R., Hodson, Mark P. and Hudson, James E. (2025). Tackling pressure fluctuations in ultra-high performance liquid chromatography to robustly resolve and analyse polar metabolites. Journal of Biological Chemistry, 301 (3) 108283, 108283. doi: 10.1016/j.jbc.2025.108283
Devilée, Lynn A. C., Salama, Abou bakr M., Miller, Jessica M., Reid, Janice D., Ou, Qinghui, Baraka, Nourhan M., Abou Farraj, Kamal, Jamal, Madiha, Nong, Yibing, Rosengart, Todd K., Andres, Douglas, Satin, Jonathan, Mohamed, Tamer M. A., Hudson, James E. and Abouleisa, Riham R. E. (2025). Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity. npj Regenerative Medicine, 10 (1) 1, 1. doi: 10.1038/s41536-025-00389-z
Orlowska, Marta K., Lor, Mary, Fitzsimmons, Rebecca L., Robinson, Harley, Delcheva, Iliana, Williams, Daniel, Priest, Craig and Hudson, James E. (2025). Robust and consistent bonding of polydimethylsiloxane to polystyrene cell culture plates. APL Materials, 13 (1) 011127. doi: 10.1063/5.0249862
Foster, Simon R. and Hudson, James E. (2024). Endothelial cells as paracrine mediators of long COVID. Nature Cardiovascular Research, 3 (10), 1181-1183. doi: 10.1038/s44161-024-00551-8
Periasamy, Parthiban, Joseph, Craig, Campos, Adrian, Rajandran, Sureka, Batho, Christopher, Hudson, James E., Sivakumaran, Haran, Kore, Hitesh, Datta, Keshava, Yeong, Joe and Gowda, Harsha (2024). Regulation of non-canonical proteins from diverse origins through the nonsense-mediated mRNA decay pathway. Proteomics, 24 (18) 2300361. doi: 10.1002/pmic.202300361
Tan, Joycelyn, Virtue, Sam, Norris, Dougall M, Conway, Olivia J, Yang, Ming, Bidault, Guillaume, Gribben, Christopher, Lugtu, Fatima, Kamzolas, Ioannis, Krycer, James R, Mills, Richard J, Liang, Lu, Pereira, Conceição, Dale, Martin, Shun-Shion, Amber S, Baird, Harry JM, Horscroft, James A, Sowton, Alice P, Ma, Marcella, Carobbio, Stefania, Petsalaki, Evangelia, Murray, Andrew J, Gershlick, David C, Nathan, James A, Hudson, James E, Vallier, Ludovic, Fisher-Wellman, Kelsey H, Frezza, Christian, Vidal-Puig, Antonio and Fazakerley, Daniel J (2024). Limited oxygen in standard cell culture alters metabolism and function of differentiated cells. EMBO Journal, 43 (11), 2127-2165. doi: 10.1038/s44318-024-00084-7
Orlowska, Marta K., Krycer, James R., Reid, Janice D., Mills, Richard J., Doran, Michael R. and Hudson, James E. (2024). A miniaturized culture platform for control of the metabolic environment. Biomicrofluidics, 18 (2) 024101, 024101. doi: 10.1063/5.0169143
Friedman, Clayton E., Cheetham, Seth W., Negi, Sumedha, Mills, Richard J., Ogawa, Masahito, Redd, Meredith A., Chiu, Han Sheng, Shen, Sophie, Sun, Yuliangzi, Mizikovsky, Dalia, Bouveret, Romaric, Chen, Xiaoli, Voges, Holly K., Paterson, Scott, De Angelis, Jessica E., Andersen, Stacey B., Cao, Yuanzhao, Wu, Yang, Jafrani, Yohaann M.A., Yoon, Sohye, Faulkner, Geoffrey J., Smith, Kelly A., Porrello, Enzo, Harvey, Richard P., Hogan, Benjamin M., Nguyen, Quan, Zeng, Jian, Kikuchi, Kazu, Hudson, James E. and Palpant, Nathan J. (2023). HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function. Developmental Cell, 59 (1), 91-107.e1. doi: 10.1016/j.devcel.2023.11.012
Voges, Holly K., Mills, Richard J., Porrello, Enzo R. and Hudson, James E. (2023). Generation of vascularized human cardiac organoids for 3D in vitro modeling. STAR Protocols, 4 (3) 102371, 1-21. doi: 10.1016/j.xpro.2023.102371
Kok, Cindy Y., Tsurusaki, Shinya, Cabanes-Creus, Marti, Igoor, Sindhu, Rao, Renuka, Skelton, Rhys, Liao, Sophia H.Y., Ginn, Samantha L., Knight, Maddison, Scott, Suzanne, Mietzsch, Mario, Fitzsimmons, Rebecca, Miller, Jessica, Mohamed, Tamer M.A., McKenna, Robert, Chong, James J.H., Hill, Adam P., Hudson, James E., Alexander, Ian E., Lisowski, Leszek and Kizana, Eddy (2023). Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes. Molecular Therapy - Methods and Clinical Development, 30, 459-473. doi: 10.1016/j.omtm.2023.08.010
ter Huurne, Menno, Parker, Benjamin L., Liu, Ning Qing, Qian, Elizabeth Ling, Vivien, Celine, Karavendzas, Kathy, Mills, Richard J., Saville, Jennifer T., Abu-Bonsrah, Dad, Wise, Andrea F., Hudson, James E., Talbot, Andrew S., Finn, Patrick F., Martini, Paolo G.V., Fuller, Maria, Ricardo, Sharon D., Watt, Kevin I., Nicholls, Kathy M., Porrello, Enzo R. and Elliott, David A. (2023). GLA-modified RNA treatment lowers GB3 levels in iPSC-derived cardiomyocytes from Fabry-affected individuals. The American Journal of Human Genetics, 110 (9), 1600-1605. doi: 10.1016/j.ajhg.2023.07.013
Chiang, Ivy K. N., Humphrey, David, Mills, Richard J., Kaltzis, Peter, Pachauri, Shikha, Graus, Matthew, Saha, Diptarka, Wu, Zhijian, Young, Paul, Sim, Choon Boon, Davidson, Tara, Hernandez‐Garcia, Andres, Shaw, Chad A., Renwick, Alexander, Scott, Daryl A., Porrello, Enzo R., Wong, Emily S., Hudson, James E., Red‐Horse, Kristy, del Monte‐Nieto, Gonzalo and Francois, Mathias (2023). Sox7‐positive endothelial progenitors establish coronary arteries and govern ventricular compaction. EMBO reports, 24 (10) e55043, 1-21. doi: 10.15252/embr.202255043
Voges, Holly K., Foster, Simon R., Reynolds, Liam, Parker, Benjamin L., Devilée, Lynn, Quaife-Ryan, Gregory A., Fortuna, Patrick R.J., Mathieson, Ellen, Fitzsimmons, Rebecca, Lor, Mary, Batho, Christopher, Reid, Janice, Pocock, Mark, Friedman, Clayton E., Mizikovsky, Dalia, Francois, Mathias, Palpant, Nathan J., Needham, Elise J., Peralta, Marina, Monte-Nieto, Gonzalo del, Jones, Lynelle K., Smyth, Ian M., Mehdiabadi, Neda R., Bolk, Francesca, Janbandhu, Vaibhao, Yao, Ernestene, Harvey, Richard P., Chong, James J.H., Elliott, David A. ... Hudson, James E. (2023). Vascular cells improve functionality of human cardiac organoids. Cell Reports, 42 (5) 112322, 112322. doi: 10.1016/j.celrep.2023.112322
Katsuno-Kambe, Hiroko, Hudson, James E., Voges, Holly K. and Yap, Alpha S. (2023). Protocol to transfer epithelial acini between different extracellular matrices and orient fibril organization. STAR Protocols, 4 (1) 102077, 102077. doi: 10.1016/j.xpro.2023.102077
McNamara, James W., Parker, Benjamin L., Voges, Holly K., Mehdiabadi, Neda R., Bolk, Francesca, Ahmad, Feroz, Chung, Jin D., Charitakis, Natalie, Molendijk, Jeffrey, Zech, Antonia T. L., Lal, Sean, Ramialison, Mirana, Karavendzas, Kathy, Pointer, Hayley L., Syrris, Petros, Lopes, Luis R., Elliott, Perry M., Lynch, Gordon S., Mills, Richard J., Hudson, James E., Watt, Kevin I., Porrello, Enzo R. and Elliott, David A. (2023). Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle. Nature Cardiovascular Research, 2 (2), 159-173. doi: 10.1038/s44161-023-00219-9
Molendijk, Jeffrey, Blazev, Ronnie, Mills, Richard J., Ng, Yaan-Kit, Watt, Kevin I., Chau, Daryn, Gregorevic, Paul, Crouch, Peter J., Hilton, James B.W., Lisowski, Leszek, Zhang, Peixiang, Reue, Karen, Lusis, Aldons J., Hudson, James, James, David E., Seldin, Marcus M. and Parker, Benjamin L. (2022). Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function. eLife, 11 e82951, 1-32. doi: 10.7554/elife.82951
Boikova, Aleksandra, Bywater, Megan J., Quaife-Ryan, Gregory A., Straube, Jasmin, Thompson, Lucy, Ascanelli, Camilla, Littlewood, Trevor D., Evan, Gerard I., Hudson, James E. and Wilson, Catherine H. (2022). HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes. Frontiers in Cardiovascular Medicine, 9 948281, 1-15. doi: 10.3389/fcvm.2022.948281
Mehdiabadi, Neda R., Boon Sim, Choon, Phipson, Belinda, Kalathur, Ravi K.R., Sun, Yuliangzi, Vivien, Celine J., ter Huurne, Menno, Piers, Adam T., Hudson, James E., Oshlack, Alicia, Weintraub, Robert G., Konstantinov, Igor E., Palpant, Nathan J., Elliott, David A. and Porrello, Enzo R. (2022). Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy. Circulation, 146 (14), 1105-1108. doi: 10.1161/circulationaha.121.057763
Krycer, James R., Lor, Mary, Fitzsimmons, Rebecca L. and Hudson, James E. (2022). A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium. Journal of Biological Chemistry, 298 (2) 101547, 1-9. doi: 10.1016/j.jbc.2021.101547
Rashidieh, Behnam, Shohayeb, Belal, Bain, Amanda Louise, Fortuna, Patrick R. J., Sinha, Debottam, Burgess, Andrew, Mills, Richard, Adams, Rachael C., Lopez, J. Alejandro, Blumbergs, Peter, Finnie, John, Kalimutho, Murugan, Piper, Michael, Hudson, James Edward, Ng, Dominic C. H. and Khanna, Kum Kum (2021). Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. PLoS Genetics, 17 (10) e1009334, 1-31. doi: 10.1371/journal.pgen.1009334
Katsuno-Kambe, Hiroko, Teo, Jessica L., Ju, Robert J., Hudson, James, Stehbens, Samantha J. and Yap, Alpha S. (2021). Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation. eLife, 10 e67915. doi: 10.7554/elife.67915
Shen, Sophie, Sun, Yuliangzi, Matsumoto, Maika, Shim, Woo Jun, Sinniah, Enakshi, Wilson, Sean B., Werner, Tessa, Wu, Zhixuan, Bradford, Stephen T., Hudson, James, Little, Melissa H., Powell, Joseph, Nguyen, Quan and Palpant, Nathan J. (2021). Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation. Trends in Molecular Medicine, 27 (12), 1135-1158. doi: 10.1016/j.molmed.2021.09.006
Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xiao, Di, Alzubaidi, Mubarak A.H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E. ... Palpant, Nathan J. (2021). Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury. Circulation, 144 (12), 947-960. doi: 10.1161/circulationaha.121.054360
Raad, Farah S., Khan, Taukeer A., Esser, Tilman U., Hudson, James E., Seth, Bhakti Irene, Fujita, Buntaro, Gandamala, Ravi, Tietze, Lutz F. and Zimmermann, Wolfram H. (2021). Chalcone‐supported cardiac mesoderm induction in human pluripotent stem cells for heart muscle engineering. ChemMedChem, 16 (21) cmdc.202100222, 3300-3305. doi: 10.1002/cmdc.202100222
Zhuang, Aowen, Calkin, Anna C., Lau, Shannen, Kiriazis, Helen, Donner, Daniel G., Liu, Yingying, Bond, Simon T., Moody, Sarah C., Gould, Eleanor A.M., Colgan, Timothy D., Carmona, Sergio Ruiz, Inouye, Michael, de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., Gregorevic, Paul, Gao, Xiao-Ming, Du, Xiao-Jun, McMullen, Julie R. and Drew, Brian G. (2021). Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner. iScience, 24 (6) 102537, 102537. doi: 10.1016/j.isci.2021.102537
Mills, Richard J., Humphrey, Sean J., Fortuna, Patrick R. J., Lor, Mary, Foster, Simon R., Quaife-Ryan, Gregory A., Johnston, Rebecca L., Dumenil, Troy, Bishop, Cameron, Rudraraju, Rajeev, Rawle, Daniel J., Le, Thuy, Zhao, Wei, Lee, Leo, Mackenzie-Kludas, Charley, Mehdiabadi, Neda R., Halliday, Christopher, Gilham, Dean, Fu, Li, Nicholls, Stephen J., Johansson, Jan, Sweeney, Michael, Wong, Norman C. W., Kulikowski, Ewelina, Sokolowski, Kamil A., Tse, Brian W. C., Devilée, Lynn, Voges, Holly K., Reynolds, Liam T. ... Hudson, James E. (2021). BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection. Cell, 184 (8), 2167-2182.e22. doi: 10.1016/j.cell.2021.03.026
Sim, Choon Boon, Phipson, Belinda, Ziemann, Mark, Rafehi, Haloom, Mills, Richard J., Watt, Kevin I., Abu-Bonsrah, Kwaku D., Kalathur, Ravi K.R., Voges, Holly K., Dinh, Doan T., Ter Huurne, Menno, Vivien, Celine J., Kaspi, Antony, Kaipananickal, Harikrishnan, Hidalgo, Alejandro, Delbridge, Leanne M.D., Robker, Rebecca L., Gregorevic, Paul, Dos Remedios, Cristobal G., Lal, Sean, Piers, Adam T., Konstantinov, Igor E., Elliott, David A., El-Osta, Assam, Oshlack, Alicia, Hudson, James E. and Porrello, Enzo R. (2021). Sex-specific control of human heart maturation by the progesterone receptor. Circulation, 143 (16), 1614-1628. doi: 10.1161/CIRCULATIONAHA.120.051921
Quaife-Ryan, Gregory A., Mills, Richard J., Lavers, George, Voges, Holly K., Vivien, Celine J., Elliott, David A., Ramialison, Mirana, Hudson, James E. and Porrello, Enzo R. (2020). β-catenin drives distinct transcriptional networks in proliferative and non-proliferative cardiomyocytes. Development (Cambridge, England), 147 (22) dev193417, dev193417. doi: 10.1242/dev.193417
Ng, Dominic C.H., Richards, Dominic K., Mills, Richard J., Ho, Uda Y., Perks, Hannah L., Tucker, Callum R., Voges, Holly K., Pagan, Julia K. and Hudson, James E. (2020). Centrosome reduction promotes terminal differentiation of human cardiomyocytes. Stem Cell Reports, 15 (4), 817-826. doi: 10.1016/j.stemcr.2020.08.007
Blazev, Ronnie, Ashwood, Christopher, Abrahams, Jodie L., Chung, Long H., Francis, Deanne, Yang, Pengyi, Watt, Kevin I., Qian, Hongwei, Quaife-Ryan, Gregory A., Hudson, James E., Gregorevic, Paul, Thaysen-Andersen, Morten and Parker, Benjamin L. (2020). Integrated glycoproteomics identifies a role of -glycosylation and galectin-1 on myogenesis and muscle development. Molecular and Cellular Proteomics, 20 100030, 1-14. doi: 10.1074/mcp.ra120.002166
Batho, Christopher A. P., Mills, Richard J. and Hudson, James E. (2020). Metabolic regulation of human pluripotent stem cell-derived cardiomyocyte maturation. Current Cardiology Reports, 22 (8) 73. doi: 10.1007/s11886-020-01303-3
Zafeiriou, Maria-Patapia, Bao, Guobin, Hudson, James, Halder, Rashi, Blenkle, Alica, Schreiber, Marie-Kristin, Fischer, Andre, Schild, Detlev and Zimmermann, Wolfram-Hubertus (2020). Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids. Nature Communications, 11 (1) 3791, 3791. doi: 10.1038/s41467-020-17521-w
Mills, Richard J. and Hudson, James E. (2020). There's no I in team: cellular crosstalk enhances in vitro cardiac maturation. Cell Stem Cell, 26 (6), 799-801. doi: 10.1016/j.stem.2020.05.009
Bywater, Megan J., Burkhart, Deborah L., Straube, Jasmin, Sabò, Arianna, Pendino, Vera, Hudson, James E., Quaife-Ryan, Gregory A., Porrello, Enzo R., Rae, James, Parton, Robert G., Kress, Theresia R., Amati, Bruno, Littlewood, Trevor D., Evan, Gerard I. and Wilson, Catherine H. (2020). Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature Communications, 11 (1) 1827, 1827. doi: 10.1038/s41467-020-15552-x
Mills, Richard and Hudson, James (2020). An in vitro model of myocardial infarction. Nature Biomedical Engineering, 4 (4), 366-367. doi: 10.1038/s41551-020-0550-9
Sreejit, Gopalkrishna, Abdel-Latif, Ahmed, Athmanathan, Baskaran, Annabathula, Rahul, Dhyani, Ashish, Noothi, Sunil K, Quaife-Ryan, Gregory A., Al-Sharea, Annas, Pernes, Gerard, Dragoljevic, Dragana, Lal, Hind, Schroder, Kate, Hanaoka, Beatriz Y., Raman, Chander, Grant, Maria B., Hudson, James E., Smyth, Susan, Porrello, Enzo R., Murphy, Andrew J. and Nagareddy, Prabhakara R. (2020). Neutrophil-derived S100A8/A9 amplify granulopoiesis following myocardial infarction. Circulation, 141 (13), 1080-1094. doi: 10.1161/CIRCULATIONAHA.119.043833
Thavapalachandran, Sujitha, Grieve, Stuart M., Hume, Robert D., Le, Thi Yen Loan, Raguram, Kalyan, Hudson, James E., Pouliopoulos, Jim, Figtree, Gemma A., Dye, Rafael P., Barry, Anthony M., Brown, Paula, Lu, Juntang, Coffey, Sean, Kesteven, Scott H., Mills, Richard J., Rashid, Fairooj N., Taran, Elena, Kovoor, Pramesh, Thomas, Liza, Denniss, Alan Robert, Kizana, Eddy, Asli, Naisana S., Xaymardan, Munira, Feneley, Michael P., Graham, Robert M., Harvey, Richard P. and Chong, James J. H. (2020). Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction. Science Translational Medicine, 12 (524) eaay2140, eaay2140. doi: 10.1126/scitranslmed.aay2140
Arasaratnam, Deevina, Bell, Katrina M., Sim, Choon Boon, Koutsis, Kathy, Anderson, David J., Qian, Elizabeth L., Stanley, Edouard G., Elefanty, Andrew G., Cheung, Michael M., Oshlack, Alicia, White, Anthony J., Abi Khalil, Charbel, Hudson, James E., Porrello, Enzo R. and Elliott, David A. (2019). Publisher Correction: The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome (Scientific Reports, (2019), 9, 1, (15928), 10.1038/s41598-019-52280-9). Scientific Reports, 9 (1) 20269. doi: 10.1038/s41598-019-55970-6
Arasaratnam, Deevina, Bell, Katrina M., Sim, Choon Boon, Koutsis, Kathy, Anderson, David J., Qian, Elizabeth L., Stanley, Edouard G., Elefanty, Andrew G., Cheung, Michael M., Oshlack, Alicia, White, Anthony J., Khalil, Charbel Abi, Hudson, James E., Porrello, Enzo R. and Elliott, David A. (2019). The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome. Scientific Reports, 9 (1) 15928, 15928. doi: 10.1038/s41598-019-52280-9
Vivien, Celine J., Pichol-Thievend, Cathy, Sim, Choon Boon, Smith, Jacob B., Bower, Neil, Hogan, Benjamin M., Hudson, James E., Francois, Mathias and Porrello, Enzo R. (2019). Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context. Npj Regenerative Medicine, 4 (1) 18, 18. doi: 10.1038/s41536-019-0079-2
Le, Thi Yen Loan, Pickett, Hilda A., Yang, Andrian, Ho, Joshua W. K., Thavapalachandran, Sujitha, Igoor, Sindhu, Yang, Sile F., Farraha, Melad, Voges, Holly K., Hudson, James E., dos Remedios, Cristobal G., Bryan, Tracy M., Kizana, Eddy and Chong, James J. H. (2019). Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells. Scientific Reports, 9 (1) 10579, 10579. doi: 10.1038/s41598-019-47022-w
Mills, Richard J., Parker, Benjamin L., Quaife-Ryan, Gregory A., Voges, Holly K., Needham, Elise J., Bornot, Aurelie, Ding, Mei, Andersson, Henrik, Polla, Magnus, Elliott, David A., Drowley, Lauren, Clausen, Maryam, Plowright, Alleyn T., Barrett, Ian P., Wang, Qing-Dong, James, David E., Porrello, Enzo R. and Hudson, James E. (2019). Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway. Cell Stem Cell, 24 (6), 895-907. doi: 10.1016/j.stem.2019.03.009
Mills, Richard J., Parker, Benjamin L., Monnot, Pauline, Needham, Elise. J., Vivien, Celine J., Ferguson, Charles, Parton, Robert G., James, David E., Porrello, Enzo R. and Hudson, James E. (2019). Development of a human skeletal micro muscle platform with pacing capabilities. Biomaterials, 198, 217-227. doi: 10.1016/j.biomaterials.2018.11.030
Mills, Richard J. and Hudson, James E. (2019). Bioengineering adult human heart tissue: how close are we?. APL Bioengineering, 3 (1) 010901, 010901. doi: 10.1063/1.5070106
Friedman, Clayton E., Nguyen, Quan, Lukowski, Samuel W., Helfer, Abbigail, Chiu, Han Sheng, Miklas, Jason, Levy, Shiri, Suo, Shengbao, Han, Jing-Dong Jackie, Osteil, Pierre, Peng, Guangdun, Jing, Naihe, Baillie, Greg J., Senabouth, Anne, Christ, Angelika N., Bruxner, Timothy J., Murry, Charles E., Wong, Emily S., Ding, Jun, Wang, Yuliang, Hudson, James, Ruohola-Baker, Hannele, Bar-Joseph, Ziv, Tam, Patrick P.L., Powell, Joseph E. and Palpant, Nathan J. (2018). Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation. Cell Stem Cell, 23 (4), 586-598. doi: 10.1016/j.stem.2018.09.009
Anderson, David J., Kaplan, David I., Bell, Katrina M., Koutsis, Katerina, Haynes, John M., Mills, Richard J., Phelan, Dean G., Qian, Elizabeth L., Leitoguinho, Ana Rita, Arasaratnam, Deevina, Labonne, Tanya, Ng, Elizabeth S., Davis, Richard P., Casini, Simona, Passier, Robert, Hudson, James E., Porrello, Enzo R., Costa, Mauro W., Rafii, Arash, Curl, Clare L., Delbridge, Lea M., Harvey, Richard P., Oshlack, Alicia, Cheung, Michael M., Mummery, Christine L., Petrou, Stephen, Elefanty, Andrew G., Stanley, Edouard G. and Elliott, David A. (2018). NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nature Communications, 9 (1) 1373, 1373. doi: 10.1038/s41467-018-03714-x
Dang, Louis T., Tondl, Markus, Chiu, Man Ho H., Revote, Jerico, Paten, Benedict, Tano, Vincent, Tokolyi, Alex, Besse, Florence, Quaife-Ryan, Greg, Cumming, Helen, Drvodelic, Mark J., Eichenlaub, Michael P., Hallab, Jeannette C., Stolper, Julian S., Rossello, Fernando J., Bogoyevitch, Marie A., Jans, David A., Nim, Hieu T., Porrello, Enzo R., Hudson, James E. and Ramialison, Mirana (2018). TrawlerWeb: an online de novo motif discovery tool for next-generation sequencing datasets. BMC Genomics, 19 (1) 238, 238. doi: 10.1186/s12864-018-4630-0
Mills, Richard J, Voges, Holly K, Porrello, Enzo R and Hudson, James E (2018). Disease modeling and functional screening using engineered heart tissue. Current Opinion in Physiology, 1, 80-88. doi: 10.1016/j.cophys.2017.08.003
Hudson, James E. and Porrello, Enzo R. (2017). FunSel mesenchymal stromal cells stay for the party. Circulation, 136 (16), 1525-1527. doi: 10.1161/CIRCULATIONAHA.117.030795
Mills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114
Quaife-Ryan, Gregory A, Sim, Choon Boon, Ziemann, Mark, Kaspi, Antony, Rafehi, Haloom, Ramialison, Mirana, El-Osta, Assam, Hudson, James E and Porrello, Enzo R (2017). Multicellular Transcriptional Analysis of Mammalian Heart Regeneration. Circulation, 136 (12), 1123-1139. doi: 10.1161/CIRCULATIONAHA.117.028252
Kaakinen, Mika, Reichelt, Melissa E., Ma, Zhibin, Ferguson, Charles, Martel, Nick, Porrello, Enzo R., Hudson, James E., Thomas, Walter G., Parton, Robert G. and Headrick, John P. (2017). Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity. Basic Research in Cardiology, 112 (3) 24, 24. doi: 10.1007/s00395-017-0613-6
Tiburcy, Malte, Hudson, James E., Balfanz, Paul, Schlick, Susanne, Meyer, Tim, Liao, Mei-Ling Chang, Levent, Elif, Raad, Farah, Zeidler, Sebastian, Wingender, Edgar, Riegler, Johannes, Wang, Mouer, Gold, Joseph D., Kehat, Izhak, Wettwer, Erich, Ravens, Ursula, Dierickx, Pieterjan, van Laake, Linda W., Goumans, Marie Jose, Khadjeh, Sara, Toischer, Karl, Hasenfuss, Gerd, Couture, Larry A., Unger, Andreas, Linke, Wolfgang A., Araki, Toshiyuki, Neel, Benjamin, Keller, Gordon, Gepstein, Lior ... Zimmermann, Wolfram-Hubertus (2017). Defined engineered human myocardium with advanced maturation for applications in heart failure modelling and repair. Circulation, 135 (19), 1832-1847. doi: 10.1161/CIRCULATIONAHA.116.024145
Hudson, James E. and Porrello, Enzo R. (2017). Periostin paves the way for neonatal heart regeneration. Cardiovascular Research, 113 (6), 556-558. doi: 10.1093/cvr/cvx039
Voges, Holly K., Mills, Richard J., Elliott, David A., Parton, Robert G., Porrello, Enzo R. and Hudson, James E. (2017). Development of a human cardiac organoid injury model reveals innate regenerative potential. Development, 144 (6), 1118-1127. doi: 10.1242/dev.143966
Vivien, Celine J, Hudson, James E and Porrello, Enzo R (2016). Evolution, comparative biology and ontogeny of vertebrate heart regeneration. NPJ Regenerative medicine, 1 (1) 16012, 16012. doi: 10.1038/npjregenmed.2016.12
Vivien, Celine J., Hudson, James E. and Porrello, Enzo R. (2016). Evolution, comparative biology and ontogeny of vertebrate heart regeneration. NPJ Regenerative Medicine, 1 16012, 1-14. doi: 10.1038/npjregenmed.2016.12
Titmarsh, Drew M., Glass, Nick R., Mills, Richard J., Hidalgo, Alejandro, Wolvetang, Ernst J., Porrello, Enzo R., Hudson, James E. and Cooper-White, Justin J. (2016). Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays. Scientific Reports, 6 (1) 24637, 24637. doi: 10.1038/srep24637
Quaife-Ryan, Gregory A., Sim, Choon Boon, Porrello, Enzo R. and Hudson, James E. (2016). Resetting the epigenome for heart regeneration. Seminars in Cell and Developmental Biology, 58, 2-13. doi: 10.1016/j.semcdb.2015.12.021
Sim, Choon Boon, Ziemann, Mark, Kaspi, Antony, Harikrishnan, K. N., Ooi, Jenny, Khurana, Ishant, Chang, Lisa, Hudson, James E., El-Osta, Assam and Porrello, Enzo R. (2015). Dynamic changes in the cardiac methylome during postnatal development.. Faseb Journal, 4 (4), 1329-1343. doi: 10.1096/fj.14-264093
Ovchinnikov, Dmitry A.,, Hidalgo, Alejandro, Yang, Seung-Kwon, Zhang, Xinli, Hudson, James, Mazzone, Stuart B., Chen, Chen, Cooper-White, Justin J. and Wolvetang, Ernst J. (2014). Isolation of contractile cardiomyocytes from human pluripotent stem-cell-derived cardiomyogenic cultures using a human NCX1-EGFP reporter. Stem Cells and Development, 24 (1), 11-20. doi: 10.1089/scd.2014.0195
Hudson, James E. and Porrello, Enzo R. (2013). The non-coding road towards cardiac regeneration. Journal of Cardiovascular Translational Research, 6 (6), 909-923. doi: 10.1007/s12265-013-9486-8
Titmarsh, Drew M., Hudson, James E., Hidalgo, Alejandro, Elefanty, Andrew G., Stanley, Edouard G., Wolvetang, Ernst J. and Cooper-White, Justin J. (2012). Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation. PLoS One, 7 (12) e52405, e52405.1-e52405.12. doi: 10.1371/journal.pone.0052405
Frith, Jessica E., Mills, Richard J., Hudson, James E. and Cooper-White, Justin J. (2012). Tailored integrin-extracellular matrix interactions to direct human mesenchymal stem cell differentiation. Stem Cells and Development, 21 (13), 2442-2456. doi: 10.1089/scd.2011.0615
Hudson, James, Titmarsh, Drew, Hidalgo, Alejandro, Wolvetang, Ernst and Cooper-White, Justin (2012). Primitive cardiac cells from human embryonic stem cells. Stem Cells and Development, 21 (9), 1513-1523. doi: 10.1089/scd.2011.0254
Christalla, Peter, Hudson, James E. and Zimmermann, Wolfram-Hubertus (2012). The cardiogenic niche as a fundamental building block of engineered myocardium. Cells Tissues Organs, 195 (1-2), 82-93. doi: 10.1159/000331407
Hudson, James E. and Zimmermann, Wolfram-Hubertus (2011). Tuning Wnt-signaling to enhance cardiomyogenesis in human embryonic and induced pluripotent stem cells. Journal of Molecular and Cellular Cardiology, 51 (3), 277-279. doi: 10.1016/j.yjmcc.2011.06.011
Hudson, James E., Brooke, Gary, Blair, Chris, Wolvetang, Ernst and Cooper-White, Justin John (2011). Development of myocardial constructs using modulus-matched acrylated polypropylene glycol triol substrate and different nonmyocyte cell populations. Tissue Engineering Part A: Tissue Engineering, 17 (17-18), 2279-2289. doi: 10.1089/ten.tea.2010.0743
Hudson, James E., Mills, Richard J., Frith, Jessica E., Brooke, Gary, Jaramillo-Ferrada, Pamela, Wolvetang, Ernst J. and Cooper-White, Justin J. (2011). A defined medium and substrate for expansion of human mesenchymal stromal cell progenitors that enriches for osteo- and chondrogenic precursors. Stem Cells and Development, 20 (1), 77-87. doi: 10.1089/scd.2009.0497
Mills, Richard J., Frith, Jessica E., Hudson, James E. and Cooper-White, Justin J. (2011). Effect of geometric challenges on cell migration. Tissue Engineering. Part C. Methods, In press (10), 999-1010. doi: 10.1089/ten.tec.2011.0138
Hudson, James E., Frith, Jessica E., Donose, Bogdan C., Rondeau, Elisabeth, Mills, Richard J., Wolvetang, Ernst J., Brooke, Gary P. and Cooper-White, Justin J. (2010). A synthetic elastomer based on acrylated polypropylene glycol triol with tunable modulus for tissue engineering applications. Biomaterials, 31 (31), 7937-7947. doi: 10.1016/j.biomaterials.2010.07.007
Markway, BD, Tan, GK, Brooke, G, Hudson, JE, Cooper-White, JJ and Doran, MR (2010). Enhanced chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in low oxygen environment micropellet cultures. Cell Transplantation, 19 (1), 29-42. doi: 10.3727/096368909X478560
Rowlands, Andrew, Hudson, James and Cooper-White, Justin J. (2007). From scrawny to brawny: the quest for neomusculogenesis; smart surfaces and scaffolds for muscle tissue engineering. Expert Review of Medical Devices, 4 (5), 709-728. doi: 10.1586/17434440.4.5.709
Conference Papers
Laskary, A., Brizard, C., Donner, D., Fitzsimmons, R., Piers, A., Watt, K., Mehdiabadi, N., Pointer, H., Hudson, J. and Porrello, E. (2024). Bioengineering Hypoxia Tolerant Human Heart Tissue with Vascularisation Potential for Transplantation. 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.030
Mellor, K., Koutsifeli, P., Varma, U., Curl, C., Janssens, J., Raaijmakers, A., Mills, R., Hudson, J., Porrello, E., Bell, J., Weeks, K. and Delbridge, L. (2024). Glycophagy is an Effective Therapeutic Target to Remediate Diastolic Dysfunction in Diabetic Heart Disease. 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.767
Pocock, Mark, Fitzsimmons, Rebecca, Lor, Mary, Foster, Simon, Doran, Michael R., Mills, Richard J. and Hudson, James E (2023). Functional Modelling Of Arrhythmias With Human Cardiac Organoids. American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023, Boston, MA United States, 31 July - 3 August 2023. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/res.133.suppl_1.p1034
Nguyen, Quan H., Lukowski, Samuel W., Chiu, Han S., Friedman, Clayton E., Senabouth, Anne, Crowhurst, Liam, Bruxner, Timothy J. C., Christ, Angelika N., Hudson, James, Ding, Jun, Bar-Joseph, Ziv, Tam, Patrick P. L., Palpant, Nathan J. and Powell, Joseph E. (2018). Genetic networks modulating cell fate specification and contributing to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution. Human Genome Meeting 2018, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications LLP. doi: 10.1186/s40246-018-0138-6
Ryan, Quaife-G., Ma, Z., Sim, C., Ramialison, M., Thomas, W., Hudson, J. and Porrello, E. (2016). Cellular transcriptomic analysis of multiple cardiac lineages during heart development and regeneration. 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide, SA Australia, 4 – 7 August 2016. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2016.06.079
Hidalgo-Gonzalez, Alejandro, Ovchinnikov, Dmitry A., Hudson, James, Cooper-White, Justin and Ernst, Wolvetang (2013). A Separable Upstream Promoter of the Slc8a1 (NCX1) Gene Efficiently Marks Cardiac Cell Populations Derived from Human Pluripotent Stem Cells. Scientific Sessions of the American Heart Association on Basic Cardiovascular Sciences, Las Vegas Nv, 22 - 25 July 2013. Baltimore, MD United States: Lippincott Williams & Wilkins.
Frith, Jessica E., Hudson, James E. and Cooper-White, Justin J. (2011). Conference scene: A bright future for tissue engineering and regenerative medicine in the Asia Pacific region. London, United Kingdom: Future Medicine. doi: 10.2217/rme.11.7
Hudson, James, Mills, Richard, Brooke, Gary and Cooper-White, Justin (2009). A degradable biopolymer with tunable modulus for control of human bone marrow mesenchymal stem cells. ISSCR 7th Annual Meeting, Barcelona, Spain, 8 – 11 July 2009. Deerfield, Illinois: International Society for Stem Cell Research.