Book Chapters
Mills, Richard J., Voges, Holly K., Porrello, Enzo R. and Hudson, James E. (2017). Cryoinjury model for tissue injury and repair in bioengineered human striated muscle. In Skeletal Muscle Development (pp. 209-224) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7283-8_15
Hudson, James E., Christalla, Peter and Zimmermann, Wolfram-Hubertus (2013). Pluripotent Stem Cell-Derived Cardiomyocytes for Industrial and Clinical Applications. Modern Biopharmaceuticals: Recent Success Stories. (pp. 57-76) Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527669417.ch3
Journal Articles
Quaife-Ryan, Gregory A., Mills, Richard J., Lavers, George, Voges, Holly K., Vivien, Celine J., Elliott, David A., Ramialison, Mirana, Hudson, James E. and Porrello, Enzo R. (2020). β-catenin drives distinct transcriptional networks in proliferative and non-proliferative cardiomyocytes. Development (Cambridge, England), 147 (22), dev193417. doi: 10.1242/dev.193417
Ng, Dominic C.H., Richards, Dominic K., Mills, Richard J., Ho, Uda Y., Perks, Hannah L., Tucker, Callum R., Voges, Holly K., Pagan, Julia K. and Hudson, James E. (2020). Centrosome reduction promotes terminal differentiation of human cardiomyocytes. Stem Cell Reports, 15 (4), 817-826. doi: 10.1016/j.stemcr.2020.08.007
Blazev, Ronnie, Ashwood, Christopher, Abrahams, Jodie L., Chung, Long H., Francis, Deanne, Yang, Pengyi, Watt, Kevin I., Qian, Hongwei, Quaife-Ryan, Gregory A., Hudson, James E., Gregorevic, Paul, Thaysen-Andersen, Morten and Parker, Benjamin L. (2020). Integrated glycoproteomics identifies a role of -glycosylation and galectin-1 on myogenesis and muscle development. Molecular and Cellular Proteomics, 20 100030, mcp.RA120.002166. doi: 10.1074/mcp.ra120.002166
Batho, Christopher A. P., Mills, Richard J. and Hudson, James E. (2020). Metabolic Regulation of Human Pluripotent Stem Cell-Derived Cardiomyocyte Maturation. Current Cardiology Reports, 22 (8) 73. doi: 10.1007/s11886-020-01303-3
Zafeiriou, Maria-Patapia, Bao, Guobin, Hudson, James, Halder, Rashi, Blenkle, Alica, Schreiber, Marie-Kristin, Fischer, Andre, Schild, Detlev and Zimmermann, Wolfram-Hubertus (2020). Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids. Nature Communications, 11 (1) 3791, 3791. doi: 10.1038/s41467-020-17521-w
Mills, Richard J. and Hudson, James E. (2020). There's No I in Team: Cellular Crosstalk Enhances In Vitro Cardiac Maturation. Cell Stem Cell, 26 (6), 799-801. doi: 10.1016/j.stem.2020.05.009
Bywater, Megan J., Burkhart, Deborah L., Straube, Jasmin, Sabò, Arianna, Pendino, Vera, Hudson, James E., Quaife-Ryan, Gregory A., Porrello, Enzo R., Rae, James, Parton, Robert G., Kress, Theresia R., Amati, Bruno, Littlewood, Trevor D., Evan, Gerard I. and Wilson, Catherine H. (2020). Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature Communications, 11 (1) 1827, 1827. doi: 10.1038/s41467-020-15552-x
Mills, Richard and Hudson, James (2020). An in vitro model of myocardial infarction. Nature Biomedical Engineering, 4 (4), 366-367. doi: 10.1038/s41551-020-0550-9
Sreejit, Gopalkrishna, Abdel-Latif, Ahmed, Athmanathan, Baskaran, Annabathula, Rahul, Dhyani, Ashish, Noothi, Sunil K, Quaife-Ryan, Gregory A., Al-Sharea, Annas, Pernes, Gerard, Dragoljevic, Dragana, Lal, Hind, Schroder, Kate, Hanaoka, Beatriz Y., Raman, Chander, Grant, Maria B., Hudson, James E., Smyth, Susan, Porrello, Enzo R., Murphy, Andrew J. and Nagareddy, Prabhakara R. (2020). Neutrophil-derived S100A8/A9 amplify granulopoiesis following myocardial infarction. Circulation, 141 (13), 1080-1094. doi: 10.1161/CIRCULATIONAHA.119.043833
Thavapalachandran, Sujitha, Grieve, Stuart M., Hume, Robert D., Le, Thi Yen Loan, Raguram, Kalyan, Hudson, James E., Pouliopoulos, Jim, Figtree, Gemma A., Dye, Rafael P., Barry, Anthony M., Brown, Paula, Lu, Juntang, Coffey, Sean, Kesteven, Scott H., Mills, Richard J., Rashid, Fairooj N., Taran, Elena, Kovoor, Pramesh, Thomas, Liza, Denniss, Alan Robert, Kizana, Eddy, Asli, Naisana S., Xaymardan, Munira, Feneley, Michael P., Graham, Robert M., Harvey, Richard P. and Chong, James J. H. (2020). Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction. Science Translational Medicine, 12 (524) eaay2140, eaay2140. doi: 10.1126/scitranslmed.aay2140
Arasaratnam, Deevina, Bell, Katrina M., Sim, Choon Boon, Koutsis, Kathy, Anderson, David J., Qian, Elizabeth L., Stanley, Edouard G., Elefanty, Andrew G., Cheung, Michael M., Oshlack, Alicia, White, Anthony J., Abi Khalil, Charbel, Hudson, James E., Porrello, Enzo R. and Elliott, David A. (2019). Publisher Correction: The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome (Scientific Reports, (2019), 9, 1, (15928), 10.1038/s41598-019-52280-9). Scientific Reports, 9 (1) 20269. doi: 10.1038/s41598-019-55970-6
Arasaratnam, Deevina, Bell, Katrina M., Sim, Choon Boon, Koutsis, Kathy, Anderson, David J., Qian, Elizabeth L., Stanley, Edouard G., Elefanty, Andrew G., Cheung, Michael M., Oshlack, Alicia, White, Anthony J., Khalil, Charbel Abi, Hudson, James E., Porrello, Enzo R. and Elliott, David A. (2019). The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome. Scientific Reports, 9 (1) 15928, 15928. doi: 10.1038/s41598-019-52280-9
Vivien, Celine J., Pichol-Thievend, Cathy, Sim, Choon Boon, Smith, Jacob B., Bower, Neil, Hogan, Benjamin M., Hudson, James E., Francois, Mathias and Porrello, Enzo R. (2019). Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context. Npj Regenerative Medicine, 4 (1) 18, 18. doi: 10.1038/s41536-019-0079-2
Le, Thi Yen Loan, Pickett, Hilda A., Yang, Andrian, Ho, Joshua W. K., Thavapalachandran, Sujitha, Igoor, Sindhu, Yang, Sile F., Farraha, Melad, Voges, Holly K., Hudson, James E., dos Remedios, Cristobal G., Bryan, Tracy M., Kizana, Eddy and Chong, James J. H. (2019). Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells. Scientific Reports, 9 (1) 10579, 10579. doi: 10.1038/s41598-019-47022-w
Mills, Richard J., Parker, Benjamin L., Quaife-Ryan, Gregory A., Voges, Holly K., Needham, Elise J., Bornot, Aurelie, Ding, Mei, Andersson, Henrik, Polla, Magnus, Elliott, David A., Drowley, Lauren, Clausen, Maryam, Plowright, Alleyn T., Barrett, Ian P., Wang, Qing-Dong, James, David E., Porrello, Enzo R. and Hudson, James E. (2019). Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway. Cell Stem Cell, 24 (6), 895-907. doi: 10.1016/j.stem.2019.03.009
Mills, Richard J., Parker, Benjamin L., Monnot, Pauline, Needham, Elise. J., Vivien, Celine J., Ferguson, Charles, Parton, Robert G., James, David E., Porrello, Enzo R. and Hudson, James E. (2019). Development of a human skeletal micro muscle platform with pacing capabilities. Biomaterials, 198, 217-227. doi: 10.1016/j.biomaterials.2018.11.030
Mills, Richard J. and Hudson, James E. (2019). Bioengineering adult human heart tissue: how close are we?. APL Bioengineering, 3 (1), 010901. doi: 10.1063/1.5070106
Friedman, Clayton E., Nguyen, Quan, Lukowski, Samuel W., Helfer, Abbigail, Chiu, Han Sheng, Miklas, Jason, Levy, Shiri, Suo, Shengbao, Han, Jing-Dong Jackie, Osteil, Pierre, Peng, Guangdun, Jing, Naihe, Baillie, Greg J., Senabouth, Anne, Christ, Angelika N., Bruxner, Timothy J., Murry, Charles E., Wong, Emily S., Ding, Jun, Wang, Yuliang, Hudson, James, Ruohola-Baker, Hannele, Bar-Joseph, Ziv, Tam, Patrick P.L., Powell, Joseph E. and Palpant, Nathan J. (2018). Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation. Cell Stem Cell, 23 (4), 586-598. doi: 10.1016/j.stem.2018.09.009
Anderson, David J., Kaplan, David I., Bell, Katrina M., Koutsis, Katerina, Haynes, John M., Mills, Richard J., Phelan, Dean G., Qian, Elizabeth L., Leitoguinho, Ana Rita, Arasaratnam, Deevina, Labonne, Tanya, Ng, Elizabeth S., Davis, Richard P., Casini, Simona, Passier, Robert, Hudson, James E., Porrello, Enzo R., Costa, Mauro W., Rafii, Arash, Curl, Clare L., Delbridge, Lea M., Harvey, Richard P., Oshlack, Alicia, Cheung, Michael M., Mummery, Christine L., Petrou, Stephen, Elefanty, Andrew G., Stanley, Edouard G. and Elliott, David A. (2018). NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nature Communications, 9 (1) 1373, 1373. doi: 10.1038/s41467-018-03714-x
Dang, Louis T., Tondl, Markus, Chiu, Man Ho H., Revote, Jerico, Paten, Benedict, Tano, Vincent, Tokolyi, Alex, Besse, Florence, Quaife-Ryan, Greg, Cumming, Helen, Drvodelic, Mark J., Eichenlaub, Michael P., Hallab, Jeannette C., Stolper, Julian S., Rossello, Fernando J., Bogoyevitch, Marie A., Jans, David A., Nim, Hieu T., Porrello, Enzo R., Hudson, James E. and Ramialison, Mirana (2018). TrawlerWeb: an online de novo motif discovery tool for next-generation sequencing datasets. BMC Genomics, 19 (1) 238, 238. doi: 10.1186/s12864-018-4630-0
Mills, Richard J, Voges, Holly K, Porrello, Enzo R and Hudson, James E (2018). Disease modeling and functional screening using engineered heart tissue. Current Opinion in Physiology, 1, 80-88. doi: 10.1016/j.cophys.2017.08.003
Hudson, James E. and Porrello, Enzo R. (2017). FunSel mesenchymal stromal cells stay for the party. Circulation, 136 (16), 1525-1527. doi: 10.1161/CIRCULATIONAHA.117.030795
Mills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114
Quaife-Ryan, Gregory A, Sim, Choon Boon, Ziemann, Mark, Kaspi, Antony, Rafehi, Haloom, Ramialison, Mirana, El-Osta, Assam, Hudson, James E and Porrello, Enzo R (2017). Multicellular Transcriptional Analysis of Mammalian Heart Regeneration. Circulation, 136 (12), 1123-1139. doi: 10.1161/CIRCULATIONAHA.117.028252
Kaakinen, Mika, Reichelt, Melissa E., Ma, Zhibin, Ferguson, Charles, Martel, Nick, Porrello, Enzo R., Hudson, James E., Thomas, Walter G., Parton, Robert G. and Headrick, John P. (2017). Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity. Basic Research in Cardiology, 112 (3) 24, 24. doi: 10.1007/s00395-017-0613-6
Tiburcy, Malte, Hudson, James E., Balfanz, Paul, Schlick, Susanne, Meyer, Tim, Liao, Mei-Ling Chang, Levent, Elif, Raad, Farah, Zeidler, Sebastian, Wingender, Edgar, Riegler, Johannes, Wang, Mouer, Gold, Joseph D., Kehat, Izhak, Wettwer, Erich, Ravens, Ursula, Dierickx, Pieterjan, van Laake, Linda W., Goumans, Marie Jose, Khadjeh, Sara, Toischer, Karl, Hasenfuss, Gerd, Couture, Larry A., Unger, Andreas, Linke, Wolfgang A., Araki, Toshiyuki, Neel, Benjamin, Keller, Gordon, Gepstein, Lior ... Zimmermann, Wolfram-Hubertus (2017). Defined engineered human myocardium with advanced maturation for applications in heart failure modelling and repair. Circulation, 135 (19), 1832-1847. doi: 10.1161/CIRCULATIONAHA.116.024145
Hudson, James E. and Porrello, Enzo R. (2017). Periostin paves the way for neonatal heart regeneration. Cardiovascular Research, 113 (6), 556-558. doi: 10.1093/cvr/cvx039
Voges, Holly K., Mills, Richard J., Elliott, David A., Parton, Robert G., Porrello, Enzo R. and Hudson, James E. (2017). Development of a human cardiac organoid injury model reveals innate regenerative potential. Development, 144 (6), 1118-1127. doi: 10.1242/dev.143966
Vivien, Celine J, Hudson, James E and Porrello, Enzo R (2016). Evolution, comparative biology and ontogeny of vertebrate heart regeneration. NPJ Regenerative medicine, 1 (1) 16012, 16012. doi: 10.1038/npjregenmed.2016.12
Vivien, Celine J., Hudson, James E. and Porrello, Enzo R. (2016). Evolution, comparative biology and ontogeny of vertebrate heart regeneration. NPJ Regenerative Medicine, 1 doi: doi:10.1038/npjregenmed.2016.12
Titmarsh, Drew M., Glass, Nick R., Mills, Richard J., Hidalgo, Alejandro, Wolvetang, Ernst J., Porrello, Enzo R., Hudson, James E. and Cooper-White, Justin J. (2016). Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays. Scientific Reports, 6 (1) 24637, 24637. doi: 10.1038/srep24637
Quaife-Ryan, Gregory A., Sim, Choon Boon, Porrello, Enzo R. and Hudson, James E. (2016). Resetting the epigenome for heart regeneration. Seminars in Cell and Developmental Biology, 58, 2-13. doi: 10.1016/j.semcdb.2015.12.021
Sim, Choon Boon, Ziemann, Mark, Kaspi, Antony, Harikrishnan, K. N., Ooi, Jenny, Khurana, Ishant, Chang, Lisa, Hudson, James E., El-Osta, Assam and Porrello, Enzo R. (2015). Dynamic changes in the cardiac methylome during postnatal development.. Faseb Journal, 4 (4), 1329-1343. doi: 10.1096/fj.14-264093
Ovchinnikov, Dmitry A.,, Hidalgo, Alejandro, Yang, Seung-Kwon, Zhang, Xinli, Hudson, James, Mazzone, Stuart B., Chen, Chen, Cooper-White, Justin J. and Wolvetang, Ernst J. (2014). Isolation of contractile cardiomyocytes from human pluripotent stem-cell-derived cardiomyogenic cultures using a human NCX1-EGFP reporter. Stem Cells and Development, 24 (1), 11-20. doi: 10.1089/scd.2014.0195
Hudson, James E. and Porrello, Enzo R. (2013). The non-coding road towards cardiac regeneration. Journal of Cardiovascular Translational Research, 6 (6), 909-923. doi: 10.1007/s12265-013-9486-8
Titmarsh, Drew M., Hudson, James E., Hidalgo, Alejandro, Elefanty, Andrew G., Stanley, Edouard G., Wolvetang, Ernst J. and Cooper-White, Justin J. (2012). Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation. PLoS One, 7 (12) e52405, e52405.1-e52405.12. doi: 10.1371/journal.pone.0052405
Frith, Jessica E., Mills, Richard J., Hudson, James E. and Cooper-White, Justin J. (2012). Tailored integrin-extracellular matrix interactions to direct human mesenchymal stem cell differentiation. Stem Cells and Development, 21 (13), 2442-2456. doi: 10.1089/scd.2011.0615
Hudson, James, Titmarsh, Drew, Hidalgo, Alejandro, Wolvetang, Ernst and Cooper-White, Justin (2012). Primitive cardiac cells from human embryonic stem cells. Stem Cells and Development, 21 (9), 1513-1523. doi: 10.1089/scd.2011.0254
Christalla, Peter, Hudson, James E. and Zimmermann, Wolfram-Hubertus (2012). The cardiogenic niche as a fundamental building block of engineered myocardium. Cells Tissues Organs, 195 (1-2), 82-93. doi: 10.1159/000331407
Hudson, James E. and Zimmermann, Wolfram-Hubertus (2011). Tuning Wnt-signaling to enhance cardiomyogenesis in human embryonic and induced pluripotent stem cells. Journal of Molecular and Cellular Cardiology, 51 (3), 277-279. doi: 10.1016/j.yjmcc.2011.06.011
Hudson, James E., Brooke, Gary, Blair, Chris, Wolvetang, Ernst and Cooper-White, Justin John (2011). Development of myocardial constructs using modulus-matched acrylated polypropylene glycol triol substrate and different nonmyocyte cell populations. Tissue Engineering Part A: Tissue Engineering, 17 (17-18), 2279-2289. doi: 10.1089/ten.tea.2010.0743
Hudson, James E., Mills, Richard J., Frith, Jessica E., Brooke, Gary, Jaramillo-Ferrada, Pamela, Wolvetang, Ernst J. and Cooper-White, Justin J. (2011). A defined medium and substrate for expansion of human mesenchymal stromal cell progenitors that enriches for osteo- and chondrogenic precursors. Stem Cells and Development, 20 (1), 77-87. doi: 10.1089/scd.2009.0497
Mills, Richard J., Frith, Jessica E., Hudson, James E. and Cooper-White, Justin J. (2011). Effect of geometric challenges on cell migration. Tissue Engineering. Part C. Methods, In press (10), 999-1010. doi: 10.1089/ten.tec.2011.0138
Hudson, James E., Frith, Jessica E., Donose, Bogdan C., Rondeau, Elisabeth, Mills, Richard J., Wolvetang, Ernst J., Brooke, Gary P. and Cooper-White, Justin J. (2010). A synthetic elastomer based on acrylated polypropylene glycol triol with tunable modulus for tissue engineering applications. Biomaterials, 31 (31), 7937-7947. doi: 10.1016/j.biomaterials.2010.07.007
Markway, BD, Tan, GK, Brooke, G, Hudson, JE, Cooper-White, JJ and Doran, MR (2010). Enhanced chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in low oxygen environment micropellet cultures. Cell Transplantation, 19 (1), 29-42. doi: 10.3727/096368909X478560
Rowlands, Andrew, Hudson, James and Cooper-White, Justin J. (2007). From scrawny to brawny: the quest for neomusculogenesis; smart surfaces and scaffolds for muscle tissue engineering. Expert Review of Medical Devices, 4 (5), 709-728. doi: 10.1586/17434440.4.5.709
Conference Papers
Nguyen, Quan H., Lukowski, Samuel W., Chiu, Han S., Friedman, Clayton E., Senabouth, Anne, Crowhurst, Liam, Bruxner, Timothy J. C., Christ, Angelika N., Hudson, James, Ding, Jun, Bar-Joseph, Ziv, Tam, Patrick P. L., Palpant, Nathan J. and Powell, Joseph E. (2018). Genetic networks modulating cell fate specification and contributing to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution. Human Genome Meeting 2018, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications LLP. doi: 10.1186/s40246-018-0138-6
Hidalgo-Gonzalez, Alejandro, Ovchinnikov, Dmitry A., Hudson, James, Cooper-White, Justin and Ernst, Wolvetang (2013). A Separable Upstream Promoter of the Slc8a1 (NCX1) Gene Efficiently Marks Cardiac Cell Populations Derived from Human Pluripotent Stem Cells. Scientific Sessions of the American Heart Association on Basic Cardiovascular Sciences, Las Vegas Nv, 22 - 25 July 2013. Baltimore, MD United States: Lippincott Williams & Wilkins.
Frith, Jessica E., Hudson, James E. and Cooper-White, Justin J. (2011). Conference scene: A bright future for tissue engineering and regenerative medicine in the Asia Pacific region. London, United Kingdom: Future Medicine. doi: 10.2217/rme.11.7
Hudson, James, Mills, Richard, Brooke, Gary and Cooper-White, Justin (2009). A degradable biopolymer with tunable modulus for control of human bone marrow mesenchymal stem cells. ISSCR 7th Annual Meeting, Barcelona, Spain, 8 – 11 July 2009. Deerfield, Illinois: International Society for Stem Cell Research.