Dr Aldo Meizoso Huesca
Postdoctoral Research Fellow
School of Biomedical Sciences
Aldo is part of the Launikonis Group - Muscle research.
Journal Articles
Pearce, Luke, Meizoso‐Huesca, Aldo, Seng, Crystal, Lamboley, Cedric R., Singh, Daniel P. and Launikonis, Bradley S. (2023). Ryanodine receptor activity and store‐operated Ca
2+
entry: critical regulators of Ca
2+
content and function in skeletal muscle. The Journal of Physiology, 601 (19), 4183-4202. doi: 10.1113/jp279512
Singh, Daniel P., Pearce, Luke, Choi, Rocky H., Meizoso-Huesca, Aldo, Wette, Stefan G., Scott, John W., Lamboley, Cedric R., Murphy, Robyn M. and Launikonis, Bradley S. (2023). Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals. Proceedings of the National Academy of Sciences, 120 (4) e2117503120, 1-12. doi: 10.1073/pnas.2117503120
Seng, Crystal, Pearce, Luke, Meizoso-Huesca, Aldo, Singh, Daniel P., Murphy, Robyn M., Lamboley, Cedric and Launikonis, Bradley S. (2022). Tiny changes in cytoplasmic [Ca2+] cause large changes in mitochondrial Ca2+: what are the triggers and functional implications?. American Journal of Physiology-Cell Physiology, 323 (4), C1285-C1289. doi: 10.1152/ajpcell.00092.2022
Meizoso-Huesca, Aldo, Pearce, Luke, Barclay, Christopher J. and Launikonis, Bradley S. (2022). Ca2+ leak through ryanodine receptor 1 regulates thermogenesis in resting skeletal muscle. Proceedings of the National Academy of Sciences, 119 (4) e2119203119, 1-8. doi: 10.1073/pnas.2119203119
Lamboley, Cedric R., Pearce, Luke, Seng, Crystal, Meizoso-Huesca, Aldo, Singh, Daniel P., Frankish, Barnaby P., Kaura, Vikas, Lo, Harriet P., Ferguson, Charles, Allen, Paul D., Hopkins, Philip M., Parton, Robert G., Murphy, Robyn M., van der Poel, Chris, Barclay, Christopher J. and Launikonis, Bradley S. (2021). Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle. Science Advances, 7 (44) eabi7166, 1-15. doi: 10.1126/sciadv.abi7166
Meizoso-Huesca, Aldo and Launikonis, Bradley S. (2021). The Orai1 inhibitor BTP2 has multiple effects on Ca2+ handling in skeletal muscle. Journal of General Physiology, 153 (1) e202012747, 1-12. doi: 10.1085/jgp.202012747
Flores-Espinoza, Emmanuel, Meizoso-Huesca, Aldo, Villegas-Comonfort, Sócrates, Reyes-Cruz, Guadalupe and García-Sáinz, J. Adolfo (2020). Effect of docosahexaenoic acid, phorbol myristate acetate, and insulin on the interaction of the FFA4 (short isoform) receptor with Rab proteins. European Journal of Pharmacology, 889 173595, 1-10. doi: 10.1016/j.ejphar.2020.173595
de Jesus Lopez-Fuentes, Antonio, Meizoso-Huesca, Aldo and Peraza-Reyes, Leonardo (2020). An endoplasmic reticulum domain is associated with the polarized growing cells of Podospora anserina hyphae. Fungal Genetics and Biology, 137 103338, 1-3. doi: 10.1016/j.fgb.2020.103338
Azimi, Iman, Stevenson, Ralph J., Zhang, Xuexin, Meizoso-Huesca, Aldo, Xin, Ping, Johnson, Martin, Flanagan, Jack U., Chalmers, Silke B., Yoast, Ryan E., Kapure, Jeevak S., Ross, Benjamin P., Vetter, Irina, Ashton, Mark R., Launikonis, Bradley S., Denny, William A., Trebak, Mohamed and Monteith, Gregory R. (2020). A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions. ACS Pharmacology and Translational Science, 3 (1) acsptsci.9b00081, 135-147. doi: 10.1021/acsptsci.9b00081
Meizoso‐Huesca, Aldo, Villegas‐Comonfort, Sócrates, Romero‐Ávila, M. Teresa and García‐Sáinz, J. Adolfo (2018). Free fatty acid receptor 4 agonists induce lysophosphatidic acid receptor 1 (
LPA
1
) desensitization independent of
LPA
1
internalization and heterodimerization. FEBS Letters, 592 (15), 2612-2623. doi: 10.1002/1873-3468.13179
Alcántara-Hernández, Rocío, Hernández-Méndez, Aurelio, Campos-Martínez, Gisselle A., Meizoso-Huesca, Aldo and García-Sáinz, J. Adolfo (2015). Phosphorylation and internalization of lysophosphatidic acid receptors LPA1, LPA2, and LPA3. PLoS ONE, 10 (10) e0140583, e0140583. doi: 10.1371/journal.pone.0140583
Conference Paper
Huesca, Aldo Meizoso, Choi, Rocky, Lamboley, Cedric, Beard, Nicole A., Blackmore, Daniel and Launikonis, Bradley S. (2025). BPS2025 - Ryanodine receptor Ca2+ leak signaling remains functionally intact and regulates energy expenditure in sedentary, aged mouse muscle. BPS2025, Los Angeles, CA, United States, 15 - 19 February 2025. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2024.11.1540